EXICURE, INC. Contracts & Agreements

Employment Agreement, dated April 27, 2023, among Exicure, Inc. and Jung S. Kim (Filed With SEC on August 11, 2023)

Separation and Release Agreement, dated April 26, 2023, among Exicure, Inc. and Matthias Schroff (Filed With SEC on August 11, 2023)

Separation and Release Agreement, dated April 26, 2023, among Exicure, Inc. and Elias Papadimas (Filed With SEC on August 11, 2023)

Convertible Bond Subscription Agreement, dated May 3, 2023, among Cyworld Z Co., Ltd. and Exicure, Inc (Filed With SEC on August 11, 2023)

Convertible Bond Subscription Agreement, dated May 16, 2023, among Cyworld Z Co., Ltd. and Exicure, Inc (Filed With SEC on August 11, 2023)

Separation and Release Agreement, dated May 27, 2023, among Exicure, Inc. and Sarah Longoria (Filed With SEC on August 11, 2023)

Amended and Restated Employment Agreement, dated May 24, 2023, among Exicure, Inc. and Joshua Miller (Filed With SEC on August 11, 2023)

Retention Agreement, dated May 24, 2023, among Exicure, Inc. and Joshua Miller (Filed With SEC on August 11, 2023)

First Amendment to the Separation and Release Agreement of Matthias Schroff, dated June 12, 2023, among Exicure, Inc. and Matthias Schroff (Filed With SEC on August 11, 2023)

First Amendment to the Separation and Release Agreement of Matthias Schroff, dated June (Filed With SEC on June 14, 2023)

Separation and Release Agreement (Filed With SEC on June 1, 2023)

Amended and Restated Employment Agreement (Filed With SEC on June 1, 2023)

Convertible Bond Subscription Agreement, dated May 16, 2023, among Cyworld Z Co., Ltd. and Exicure, Inc (Filed With SEC on May 18, 2023)

Convertible Bond Subscription Agreement, dated May 3, 2023, among Cyworld Z Co., Ltd. and Exicure, Inc (Filed With SEC on May 9, 2023)

Employment Agreement, dated April 27, 2023, among Exicure, Inc. and Jung S. Kim (Filed With SEC on May 2, 2023)

Separation and Release Agreement, dated April 26, 2023, among Exicure, Inc. and Matthias Schroff (Filed With SEC on May 2, 2023)

Separation and Release Agreement (Filed With SEC on May 2, 2023)

Employment Agreement by and between Exicure, Inc. and Sarah Longoria, dated March 5, 2021 (Filed With SEC on March 27, 2023)

First Amendment to Employment Agreement by and between Exicure, Inc. and Sarah Longoria, dated December 10, 2021 (Filed With SEC on March 27, 2023)

Second Amendment to Employment Agreement by and between Exicure, Inc. and Sarah Longoria, dated September 23, 2022 (Filed With SEC on March 27, 2023)

Mutual Termination Agreement, dated December 12, 2022, by and between Exicure, Inc. and Ipsen Biopharm Limited (Filed With SEC on December 14, 2022)

Letter Agreement, dated December 13, 2022, by and between Exicure, Inc. and Allergan Pharmaceuticals International Limited (Filed With SEC on December 14, 2022)

Amendment Six to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of October 10, 2022 (Filed With SEC on November 14, 2022)

Side Letter to Securities Purchase Agreement, dated October 31, 2022, by and between Exicure, Inc. and CBI USA, Inc (Filed With SEC on October 31, 2022)

Securities Purchase Agreement, dated September 26, 2022, by and between Exicure, Inc. and CBI USA (Filed With SEC on September 27, 2022)

Registration Rights Agreement, dated September 26, 2022, by and between Exicure, Inc. and CBI USA (Filed With SEC on September 27, 2022)

First Amendment to the Second Amended and Restated Employment Agreement, by and between Exicure, Inc. and Matthias Schroff, dated September 23, 2022 (Filed With SEC on September 27, 2022)

Second Amendment to the Amended and Restated Employment Agreement, by and between Exicure, Inc. and Elias Papadimas, dated September 23, 2022 (Filed With SEC on September 27, 2022)

Form of Restricted Stock Unit Award Agreement under the 2017 Equity Incentive Plan (Filed With SEC on August 15, 2022)

Securities Purchase Agreement, dated May 9, 2022, by and among Exicure, Inc. and the purchasers party thereto (Filed With SEC on May 13, 2022)

Registration Rights Agreement, dated May 9, 2022, by and among Exicure, Inc. and the purchasers party thereto (Filed With SEC on May 13, 2022)

Retention Agreement by and between Exicure, Inc. and Elias D. Papadimas (Filed With SEC on March 25, 2022)

Advisor Agreement by and between Exicure, Inc. and Brian C. Bock (Filed With SEC on February 4, 2022)

Second Amended and Restated Employment Agreement by and between Exicure, Inc. and Matthias Schroff, Ph.D (Filed With SEC on February 4, 2022)

Separation and Transition Agreement by and between Exicure, Inc. and David A. Giljohann, Ph.D (Filed With SEC on February 4, 2022)

First Amendment to Amended and Restated Employment Agreement between (Filed With SEC on January 18, 2022)

Form of Warrant (Filed With SEC on December 16, 2021)

Form of Pre-Funded Warrant (Filed With SEC on December 16, 2021)

Form of Securities Purchase Agreement, dated December 14, 2021 by and among Exicure, Inc. and the purchasers party thereto (Filed With SEC on December 16, 2021)

Amendment No. 4 dated as of December 10, 2021 to Credit and Security Agreement, dated as of September 25, 2020 by and among Exicure, Inc., Exicure Operating Company, the lenders... (Filed With SEC on December 10, 2021)

First Amendment to the Employment Agreement, by and between Exicure, Inc. and Brian Bock, dated December 10, 2021 (Filed With SEC on December 10, 2021)

Second Amendment to the Employment Agreement, by and between Exicure, Inc. and Matthias Schroff, dated December 10, 2021 (Filed With SEC on December 10, 2021)

Collaboration, Option and License Agreement between Exicure, Inc. and Ipsen Biopharm Limited dated as of July 30, 2021 (Filed With SEC on November 19, 2021)

Side Agreement to Northwestern Agreements by and among Exicure Inc., Northwestern University and Ipsen Biopharm Limited dated as of July 30, 2021 (Filed With SEC on November 19, 2021)

Amendment Five to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of September 8, 2021 (Filed With SEC on November 19, 2021)

Amendment No. 3, dated as of September 30, 2021, to Credit and Security Agreement, dated as of September 25, 2020, by and among Exicure, Inc., Exicure Operating Company, the... (Filed With SEC on October 6, 2021)

Amended and Restated Employment Agreement between Exicure, Inc. and Elias D. Papadimas, dated June 1, 2021 (Filed With SEC on August 12, 2021)

Amendment No. 2 dated as of July 30, 2021 to Credit and Security Agreement, dated as of September 25, 2020 by and among Exicure, Inc., Exicure Operating Company, the lenders party... (Filed With SEC on August 12, 2021)

Employment Agreement between the Company and Brian Bock, dated April 16, 2021 (Filed With SEC on May 13, 2021)

Inducement Award Agreement between the Company and Brian Bock, dated May 13, 2021 (Filed With SEC on May 13, 2021)

Form of Restricted Share Unit Award Agreement (Filed With SEC on May 12, 2021)

Amendment No. 1 (Filed With SEC on November 12, 2020)

Credit and Security Agreement, dated as of September 25, 2020, by and among Exicure, Inc., Exicure Operating Company, the lenders party thereto from time to time and MidCap... (Filed With SEC on October 1, 2020)

Amended and Restated Employment Agreement dated as of (Filed With SEC on August 12, 2020)

Form of Executive Employment Side Letter Agreement (Filed With SEC on June 9, 2020)

Lease Agreement dated as of February 28, 2020 by and between 2430 N. Halsted, LLC and Exicure, Inc (Filed With SEC on May 14, 2020)

Description of Securities (Filed With SEC on March 10, 2020)

Amended and Restated Employment Agreement as of December 10, 2019 by and between Exicure, Inc. and Matthias G. Schroff, Ph.D (Filed With SEC on March 10, 2020)

Amendment Two to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of November 30, 2017 (Filed With SEC on March 10, 2020)

Amendment Four to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of November 13, 2019 (Filed With SEC on March 10, 2020)

Amendment One dated and effective as of June 11, 2018 to the License Agreement between Exicure OpCo and Northwestern University dated as of February 10, 2016 and effective as of... (Filed With SEC on March 10, 2020)

Amendment Two dated and effective as of November 13, 2019 to the License Agreement between Exicure OpCo and Northwestern University dated as of February 10, 2016 and effective as... (Filed With SEC on March 10, 2020)

Side Agreement to Northwestern Agreements by and among Exicure Inc., Northwestern University and Allergan Pharmaceuticals International Limited dated as of November 13, 2019 (Filed With SEC on March 10, 2020)

Amendment One dated and effective June 11, 2018 to the License Agreement between Exicure OpCo and Northwestern University dated as of June 17, 2016 (Filed With SEC on March 10, 2020)

Amendment Three to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of January 1, 2019 (Filed With SEC on March 10, 2020)

Collaboration, Option and License Agreement between Exicure, Inc. and Allergan Pharmaceuticals International Limited dated as of November 13, 2019 (Filed With SEC on March 10, 2020)

Underwriting Agreement, dated December 19, 2019, between the Company and Guggenheim Securities, LLC, as representative of the several underwriters named therein (Filed With SEC on December 23, 2019)

Underwriting Agreement, dated July 30, 2019, between the Company and Guggenheim Securities, LLC, as representative of the several underwriters named therein (Filed With SEC on August 2, 2019)

License and Development Agreement between Exicure, Inc. and DERMELIX LLC dated February 17, 2019 (Filed With SEC on May 8, 2019)

Amendment No. 4 to Loan and Security Agreement dated as of March 8, 2019 by and between the Company and Hercules (Filed With SEC on March 14, 2019)

Amendment No. 3 to Loan and Security Agreement dated as of December 28, 2018 by and between Exicure OpCo and Hercules (Filed With SEC on March 8, 2019)

Form of Registration Rights Agreement by and among the Company and the persons named therein (Filed With SEC on August 28, 2018)

Form of Subscription Agreement by and between the Company and each investor in connection with the initial closing of the Private Placement (Filed With SEC on August 28, 2018)

Offer Letter dated as of January 18, 2018 by and between Exicure, Inc. and Matthias G. Schroff, Ph.D (Filed With SEC on May 15, 2018)

Amendment No. 2 to Loan and Security Agreement dated as of January 15, 2018 by and between Exicure OpCo and Hercules (Filed With SEC on January 26, 2018)

Restated License Agreement between Exicure OpCo and Northwestern University dated as of August 15, 2015 (Filed With SEC on November 7, 2017)

License Agreement between Exicure OpCo and Northwestern University dated as of February 10, 2016 and effective as of May 27, 2014 (Filed With SEC on November 7, 2017)

License Agreement between Exicure OpCo and Northwestern University dated as of June 17, 2016 (Filed With SEC on November 7, 2017)

Amendment One to the Amended Restated License Agreement between Exicure OpCo and Northwestern University dated as of September 27, 2016 (Filed With SEC on November 7, 2017)

Form of Subscription Agreement by and between the Company and each investor in connection with the Subsequent Closing (Filed With SEC on November 2, 2017)

Form of Purchaser Rights Letter to be delivered by the Company to each investor in the initial closing of the Private Placement (Filed With SEC on November 2, 2017)

Agreement and Plan of Merger and Reorganization, dated September 26, 2017, by and among Max-1 Acquisition Corporation, Acquisition Sub, a Delaware corporation and wholly-owned... (Filed With SEC on October 2, 2017)

Form of Warrant to Purchase Shares of Common Stock issued to Placement Agent (Filed With SEC on October 2, 2017)

Form of Registration Rights Agreement by and among the Company and the persons named therein (Filed With SEC on October 2, 2017)

2015 Equity Incentive Plan and forms of awards thereunder, assumed in the Merger (Filed With SEC on October 2, 2017)

2017 Equity Incentive Plan and forms of award agreements thereunder (Filed With SEC on October 2, 2017)

2017 Employee Stock Purchase Plan (Filed With SEC on October 2, 2017)

Form of Indemnification Agreement by and between the Company and each of its directors and executive officers (Filed With SEC on October 2, 2017)

Form of Subscription Agreement by and between the Company and each investor in the Offering (Filed With SEC on October 2, 2017)

Form of Amended and Restated Board Member Service Agreement by and between Exicure OpCo and each of its non-executive directors (Filed With SEC on October 2, 2017)

Employment Agreement dated as of February 2, 2016 by and between Exicure OpCo and David A. Giljohann, Ph.D (Filed With SEC on October 2, 2017)

Amended and Restated Employment Agreement dated as of February 2, 2016 by and between Exicure OpCo and David S. Snyder (Filed With SEC on October 2, 2017)

Employment Offer Letter dated as of September 16, 2015 by and between Exicure OpCo and Ekambar Kandimalla, Ph.D (Filed With SEC on October 2, 2017)

First Amendment to Offer Letter dated as of January 8, 2016 by and between Exicure OpCo and Ekambar Kandimalla, Ph.D (Filed With SEC on October 2, 2017)

Consulting Agreement dated as of October 1, 2011 by and between AuraSense Therapeutics, LLC and Chad A. Mirkin, Ph.D (Filed With SEC on October 2, 2017)

Lease Agreement dated as of February 13, 2012 by and between AuraSense Therapeutics, LLC and FC Skokie SPE, LLC (Filed With SEC on October 2, 2017)

Letter dated as of March 12, 2012 regarding the Lease Agreement by and between AuraSense Therapeutics, LLC and FC Skokie SPE, LLC (Filed With SEC on October 2, 2017)

First Amendment to Lease dated as of March 31, 2014 by and between AuraSense Therapeutics, LLC and FC Skokie PQ, LLC, as successor in interest to FC Skokie SPE, LLC (Filed With SEC on October 2, 2017)

Second Amendment to Lease dated as of May 26, 2016 by and between Exicure OpCo and FC Skokie PQ, LLC, as successor in interest to FC Skokie SPE, LLC (Filed With SEC on October 2, 2017)

Loan and Security Agreement dated as of February 17, 2016 by and between Exicure OpCo and Hercules (Filed With SEC on October 2, 2017)

Amendment No. 1 to Loan and Security Agreement dated as of October 10, 2016 by and between Exicure OpCo and Hercules (Filed With SEC on October 2, 2017)

Form of Pre-Merger Indemnity Agreement (Filed With SEC on October 2, 2017)

Form of Common Stock Purchase Agreement (Filed With SEC on June 19, 2017)

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EXICURE, INC. Contracts & Agreements