SYNLOGIC, INC. Contracts & Agreements

Amendment to Separation Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of February 17, 2024 (Filed With SEC on November 12, 2024)

Amendment to Retention Bonus Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of March 7, 2024 (Filed With SEC on November 12, 2024)

Amendment to Separation Agreement by and between Synlogic, Inc. and Mary Beth Dooley, dated as of February 17, 2024 (Filed With SEC on November 12, 2024)

Amendment to Retention Bonus Agreement by and between Synlogic, Inc. and Mary Beth Dooley, dated as of March 7, 2024 (Filed With SEC on November 12, 2024)

Lease Termination Agreement by and between BMR-Rogers Street LLC and Synlogic, Inc (Filed With SEC on August 8, 2024)

First Amendment to Separation Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of February 17, 2024 (Filed With SEC on August 8, 2024)

First Amendment to Retention Bonus Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of March 7, 2024 (Filed With SEC on August 8, 2024)

First Amendment to Separation Agreement by and between Synlogic, Inc. and Mary Beth Dooley, dated as of February 17, 2024 (Filed With SEC on August 8, 2024)

First Amendment to Retention Bonus Agreement by and between Synlogic, Inc. and Mary Beth Dooley, dated as of March 7, 2024 (Filed With SEC on August 8, 2024)

Statement of Work dated May 3, 2024 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW P-Cleanroom... (Filed With SEC on May 14, 2024)

2023 Inducement Equity Incentive Award Plan (Filed With SEC on March 19, 2024)

Form of Stock Option Grant Notice and Stock Option Agreement under 2023 Inducement Equity Incentive Award Plan (Filed With SEC on March 19, 2024)

Separation Agreement by and between Synlogic, Inc. and Aoife M. Brennan, MB, BCh, BAO, MMSc, dated as of February 17, 2024 (Filed With SEC on March 19, 2024)

Separation Agreement by and between Synlogic, Inc. and Michael Jensen, dated as of November 13, 2023 (Filed With SEC on March 19, 2024)

Separation Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of February 17, 2024 (Filed With SEC on March 19, 2024)

Retention Bonus Agreement by and between Synlogic, Inc. and Antoine Awad, dated as of March 7, 2024 (Filed With SEC on March 19, 2024)

Employment Letter Agreement dated April 11, 2018 by and between Synlogic, Inc. and Mary Beth Dooley (Filed With SEC on March 19, 2024)

Retention Bonus Agreement by and between Synlogic, Inc. and Mary Beth Dooley, dated as of March 7, 2024 (Filed With SEC on March 19, 2024)

Addendum to Statement of Work dated December 8, 2023 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW... (Filed With SEC on March 19, 2024)

Rights Agreement, dated as of February 20, 2024, between Synlogic, Inc. and Equiniti Trust Company LLC, as rights agent (Filed With SEC on February 20, 2024)

Amendment to Employment Agreement dated December 26, 2023, by and between the Company and Aoife Brennan (Filed With SEC on December 29, 2023)

Amendment to Employment Agreement dated December 26, 2023, by and between the Company and Antoine Awad (Filed With SEC on December 29, 2023)

Amendment to Pilot Collaboration and Option Agreement, dated as of August 16, 2023, among Synlogic Operating Company, Inc. and Hoffman-La Roche Inc (Filed With SEC on November 9, 2023)

Form of Underwriting Agreement dated September 28, 2023 (Filed With SEC on September 29, 2023)

Form of Pre-Funded Warrant (Filed With SEC on September 29, 2023)

Form of Purchase Warrant (Filed With SEC on September 29, 2023)

Form of Underwriting Agreement, by and between the Registrant and Chardan Capital Markets LLC (Filed With SEC on September 27, 2023)

Form of Pre-Funded Warrant (Filed With SEC on September 27, 2023)

Form of Common Warrant (Filed With SEC on September 27, 2023)

Statement of Work dated January 21, 2022 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW P-10558-01 (Filed With SEC on March 17, 2022)

Statement of Work dated January 21, 2022 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW P-10558-2 (Filed With SEC on March 17, 2022)

Employment Agreement dated as of January 24, 2022, by and between the Company and Michael Jensen (Filed With SEC on March 3, 2022)

Underwriting Agreement, dated September 22, 2021, among Synlogic, Inc. and Jefferies LLC and SVB Leerink LLC, as representatives of the several underwriters named therein (Filed With SEC on September 23, 2021)

License and Services Agreement and Statement of Work, dated April 28, 2021, by and between Synlogic Operating Company, Inc. and Azzur Cleanrooms-On-Demand Boston, LLC (Filed With SEC on August 12, 2021)

Pilot Collaboration and Option Agreement, dated June 16, 2021, among Synlogic Operating Company, Inc. and Hoffman-La Roche Inc (Filed With SEC on August 12, 2021)

Underwriting Agreement, dated April 15, 2021, among Synlogic, Inc. and SVB Leerink LLC, as representative of the several underwriters named therein (Filed With SEC on April 16, 2021)

Employment Letter Agreement dated July 17, 2019, by and between Synlogic and Richard Riese (Filed With SEC on March 25, 2021)

Employment Letter Agreement dated November 28, 2018, by and between Synlogic and Antoine Awad (Filed With SEC on March 25, 2021)

Promotion Letter, dated July 21, 2020, for Antoine Awad (Filed With SEC on March 25, 2021)

Amendment No. 1 to the Subscription Agreement dated as of April 1, 2020, by and between the Company and Ginkgo Bioworks, Inc (Filed With SEC on May 8, 2020)

Description of Securities (Filed With SEC on March 12, 2020)

Non-Employee Director Compensation Program (Filed With SEC on January 31, 2020)

Synlogic, Inc. 2015 Employee Stock Purchase Plan, as amended (Filed With SEC on December 20, 2019)

Consulting Agreement effective as of October 13, 2019, by and between the Company and Danforth Advisors, LLC, as amended (Filed With SEC on October 24, 2019)

Foundry Terms of Service Agreement, dated as of June 11, 2019, by and between Synlogic Operating Company, Inc., and Ginkgo Bioworks, Inc (Filed With SEC on August 8, 2019)

Pre-Funded Warrant (Filed With SEC on June 12, 2019)

Subscription Agreement, dated as of June 11, 2019, by and between Synlogic, Inc. and Ginkgo Bioworks, Inc (Filed With SEC on June 12, 2019)

Separation Agreement, dated as of December 17, 2018 by and between Andrew Gengos and Synlogic, Inc (Filed With SEC on May 9, 2019)

Third Amendment to Agreement and Plan of Merger and First Amendment to License Agreement by and among AbbVie S..r.l., Synlogic IBDCo, Inc. and Synlogic Operating Company, Inc.,... (Filed With SEC on March 12, 2019)

Master Contract Services Agreement, dated as of September 8, 2018, between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC) (Filed With SEC on March 12, 2019)

Statement of Work dated September 10, 2018 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC) (Filed With SEC on March 12, 2019)

Statement of Work dated December 7, 2018 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC) (Filed With SEC on March 12, 2019)

Amended and Restated Letter Agreement by and between Synlogic, Inc. and Aoife M. Brennan, MB, BCh, BAO, MMSc, dated as of October 1, 2018 (Filed With SEC on November 13, 2018)

Second Amendment to Agreement and Plan of Merger by and among AbbVie S..r.l., Synlogic IBDCo, Inc. and Synlogic Operating Company, Inc., dated as of September 27, 2018 (Filed With SEC on November 13, 2018)

Third Amendment to Offer Letter dated as of June 5, 2018, between Synlogic, Inc. and Aoife Brennan, MB, BCh, BAO, MMSc (Filed With SEC on August 9, 2018)

Amendment to Option Agreements dated as of June 5, 2018, between Synlogic, Inc. and Jose-Carlos Gutirrez-Ramos (Filed With SEC on August 9, 2018)

Letter Agreement dated as of May 9, 2018, between Synlogic, Inc. and Jose-Carlos Gutirrez-Ramos (Filed With SEC on May 15, 2018)

Placement Agency Agreement dated as of April 6, 2018, by and between Synlogic, Inc. and Leerink Partners LLC (Filed With SEC on April 6, 2018)

Form of Subscription Agreement, dated as of April 6, 2018, by and among Synlogic, Inc. and the Investors (Filed With SEC on April 6, 2018)

2015 Equity Incentive Award Plan (Filed With SEC on March 20, 2018)

2017 Stock Incentive Plan (Filed With SEC on March 20, 2018)

NonEmployee Director Compensation Program (Filed With SEC on March 20, 2018)

Lease by and between BMR-Rogers Street LLC and the registrant (Filed With SEC on March 20, 2018)

Underwriting Agreement, dated January 23, 2018, among Synlogic, Inc. and Leerink Partners LLC and Piper Jaffray & Co., as representatives of the several underwriters named therein (Filed With SEC on January 24, 2018)

2017 Stock Incentive Plan (Filed With SEC on November 13, 2017)

Form of Stock Option Grant Notice and Stock Option Agreement under 2017 Stock Incentive Plan (Filed With SEC on November 13, 2017)

Sales Agreement, dated as of October 13, 2017, between the Company and Cowen and Company, LLC (Filed With SEC on October 16, 2017)

Employment Agreement, dated as of September 4, 2017, by and between the Company and Andrew W. Gengos (Filed With SEC on October 10, 2017)

Offer Letter by and between Synlogic and Jose Carlos Gutierrez-Ramos, Ph.D., dated as of March 20, 2015 (Filed With SEC on August 28, 2017)

First Amendment to Offer Letter by and between Synlogic and Jose Carlos Gutierrez-Ramos, Ph.D., dated as of May 8, 2017 (Filed With SEC on August 28, 2017)

Offer Letter by and between Synlogic and Todd Shegog, dated as of June 17, 2016 (Filed With SEC on August 28, 2017)

First Amendment to Offer Letter by and between Synlogic and Todd Shegog, dated as of May 8, 2017 (Filed With SEC on August 28, 2017)

Offer Letter by and between Synlogic and Aoife M. Brennan, MB, BCh, BAO, MMSc, dated as of June 22, 2016 (Filed With SEC on August 28, 2017)

First Amendment to Offer Letter by and between Synlogic and Aoife M. Brennan, MB, BCh, BAO, MMSc, dated as of November 7, 2016 (Filed With SEC on August 28, 2017)

Second Amendment to Offer Letter by and between Synlogic and Aoife M. Brennan, MB, BCh, BAO, MMSc, dated as of May 8, 2017 (Filed With SEC on August 28, 2017)

Amended and Restated Letter Agreement by and between Paul Miller, Ph.D., dated as of May 16, 2017 (Filed With SEC on August 28, 2017)

Separation Agreement by and between the Company and Paul Lammers, dated as of August 20, 2017 (Filed With SEC on August 28, 2017)

Separation Agreement by and between the Company and Alan Fuhrman, dated as of August 20, 2017 (Filed With SEC on August 28, 2017)

Agreement and Plan of Merger by and among AbbVie S..r.l., Suffolk Merger Sub, Inc., Synlogic IBDCo, Inc., Synlogic, LLC, Synlogic, Inc. and the founders named therein, dated as of... (Filed With SEC on August 28, 2017)

License Agreement by and between Synlogic, Inc. and Synlogic IBDCo, Inc., dated as of July 16, 2015 (Filed With SEC on August 28, 2017)

License Agreement by and among Trustees of Boston University, Massachusetts Institute of Technology and Synlogic, Inc., dated as of October 18, 2015 (Filed With SEC on August 28, 2017)

Exclusive Patent License Agreement by and between Massachusetts Institute of Technology and Synlogic, Inc., dated as of November 9, 2015; as amended by a Letter Agreement by and... (Filed With SEC on August 28, 2017)

LEASE TERMINATION AGREEMENT AND RELEASE (Filed With SEC on June 21, 2017)

AGREEMENT AND PLAN OF MERGER AND REORGANIZATION among: MIRNA THERAPEUTICS, INC., a Delaware corporation; MEERKAT MERGER SUB, INC., a Delaware corporation; and SYNLOGIC, INC., a... (Filed With SEC on May 16, 2017)

FORM OF SUPPORT AGREEMENT (Filed With SEC on May 16, 2017)

FORM OF LOCK-UP AGREEMENT (Filed With SEC on May 16, 2017)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on March 15, 2017)

Exhibit 10.26(B) (Filed With SEC on March 15, 2017)

LEASE (Filed With SEC on August 15, 2016)

SEPARATION AGREEMENT (Filed With SEC on August 15, 2016)

TRANSITION AND SEPARATION AGREEMENT (Filed With SEC on August 15, 2016)

PATENT LICENSE AGREEMENT (Filed With SEC on March 30, 2016)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on October 6, 2015)

APPENDIX (Filed With SEC on September 30, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on September 25, 2015)

MIRNA THERAPEUTICS, INC. (a Delaware corporation) Shares of Common Stock UNDERWRITING AGREEMENT (Filed With SEC on September 18, 2015)

AMENDMENT No. 1 to LICENSE AGREEMENT (Filed With SEC on September 18, 2015)

APPENDIX (Filed With SEC on September 18, 2015)

AMENDMENT No. 2 to LICENSE AGREEMENT (Filed With SEC on September 18, 2015)

MIRNA THERAPEUTICS, INC. 2015 EQUITY INCENTIVE AWARD PLAN* ARTICLE 1. PURPOSE (Filed With SEC on September 18, 2015)

MIRNA THERAPEUTICS, INC. 2015 EMPLOYEE STOCK PURCHASE PLAN* ARTICLE I. PURPOSE, SCOPE AND ADMINISTRATION OF THE PLAN (Filed With SEC on September 18, 2015)

MIRNA THERAPEUTICS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM* (Filed With SEC on September 18, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on September 18, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] AMENDMENT NO. 1 TO THE EMPLOYMENT AGREEMENT (Filed With SEC on September 18, 2015)

[MIRNA THERAPEUTICS LOGO] (Filed With SEC on September 18, 2015)

MIRNA THERAPEUTICS, INC. THIRD AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (Filed With SEC on September 11, 2015)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on September 11, 2015)

LICENSE AGREEMENT (Filed With SEC on September 11, 2015)

AMENDMENT No. 1 to LICENSE AGREEMENT (Filed With SEC on September 11, 2015)

APPENDIX (Filed With SEC on September 11, 2015)

AMENDMENT No. 2 to LICENSE AGREEMENT (Filed With SEC on September 11, 2015)

Mirna Therapeutics Inc. | 2150 Woodward St., Suite 100 | Austin, TX 78744 | 1 ###-###-#### | www.mirnarx.com (Filed With SEC on September 11, 2015)

AMENDED AND RESTATED AGREEMENT (Filed With SEC on September 11, 2015)

LICENSE AGREEMENT (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. 2015 EQUITY INCENTIVE AWARD PLAN ARTICLE 1. PURPOSE (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. 2015 EQUITY INCENTIVE AWARD PLAN STOCK OPTION GRANT NOTICE (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. 2015 EQUITY INCENTIVE AWARD PLAN RESTRICTED STOCK AWARD GRANT NOTICE (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. 2015 EMPLOYEE STOCK PURCHASE PLAN ARTICLE I. PURPOSE, SCOPE AND ADMINISTRATION OF THE PLAN (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. CHANGE IN CONTROL SEVERANCE AGREEMENT (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. INDEMNIFICATION AGREEMENT (Filed With SEC on September 11, 2015)

STOCK PURCHASE AGREEMENT (Filed With SEC on September 11, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on September 11, 2015)

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on September 11, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on September 11, 2015)

WITNESSETH (Filed With SEC on September 11, 2015)

[MIRNA THERAPEUTICS LETTERHEAD] (Filed With SEC on September 11, 2015)

MIRNA THERAPEUTICS, INC. SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (Filed With SEC on August 24, 2015)

SERVICES AGREEMENT Between ASURAGEN, INC. and MIRNA THERAPEUTICS, INC. Dated January 1, 2013 (Filed With SEC on August 24, 2015)

AMENDMENT NO.1 TO THE SERVICES AGREEMENT (Filed With SEC on August 24, 2015)

CROSS LICENSE AGREEMENT (Filed With SEC on August 24, 2015)

FIRST AMENDMENT TO THE CROSS LICENSE AGREEMENT (Filed With SEC on August 24, 2015)

LICENSE AGREEMENT (Filed With SEC on August 24, 2015)

APPENDIX (Filed With SEC on August 24, 2015)

AMENDMENT No. 1 to LICENSE AGREEMENT (Filed With SEC on August 24, 2015)

APPENDIX (Filed With SEC on August 24, 2015)

AMENDED AND RESTATED AGREEMENT (Filed With SEC on August 24, 2015)

LICENSE AGREEMENT (Filed With SEC on August 24, 2015)

CANCER PREVENTION & RESEARCH INSTITUTE OF TEXAS (Filed With SEC on August 24, 2015)

Supply Agreement for a Liposomal Formulation November 2012 (Filed With SEC on August 24, 2015)

MIRNA THERAPEUTICS, INC. 2008 LONG TERM INCENTIVE PLAN (Filed With SEC on August 24, 2015)

MIRNA THERAPEUTICS, INC. 2150 Woodward St. #100 Austin, Texas 78744 , 20 NOTICE OF GRANT OF STOCK OPTION (Filed With SEC on August 24, 2015)

MIRNA THERAPEUTICS, INC. 2008 LONG TERM INCENTIVE PLAN STOCK OPTION AGREEMENT (Filed With SEC on August 24, 2015)

SUBLEASE (Filed With SEC on August 24, 2015)

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SYNLOGIC, INC. Contracts & Agreements