COLLEGIUM PHARMACEUTICAL, INC Contracts & Agreements

Authorized Generic Agreement by and between the Company and Hikma Pharmaceuticals USA Inc., dated April 26, 2024 (Filed With SEC on August 8, 2024)

Separation Agreement, by and between the Company and Joseph Ciaffoni, dated May 24, 2024 (Filed With SEC on August 8, 2024)

Letter Agreement, by and between the Company and Michael Heffernan, dated May 24, 2024 (Filed With SEC on August 8, 2024)

Agreement and Plan of Merger, dated as of July 28, 2024, by and among the Company, Ironshore Therapeutics Inc. and Shareholder Representative Services LLC (Filed With SEC on July 29, 2024)

Second Amended and Restated Loan Agreement by and among the Company, its subsidiaries party thereto; BioPharma Credit PLC, as collateral agent and lender; BPCR Limited... (Filed With SEC on July 29, 2024)

Form of Restricted Stock Unit Agreement under the Amended and Restated 2014 Stock Incentive Plan (Filed With SEC on February 22, 2024)

First Amendment and Consent to Amended and Restated Loan Agreement, dated as of January 3, 2023, by and among Collegium Pharmaceutical, Inc., the guarantors party thereto,... (Filed With SEC on February 22, 2024)

Third Amendment to Loan Agreement, dated as of June 23, 2023, by and among Collegium Pharmaceutical, Inc., the guarantors party thereto, BioPharma Credit PLC, and Bio Pharma... (Filed With SEC on August 3, 2023)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 23, 2023)

Second Amendment to Loan Agreement, dated as of February 6, 2023, Amended and Restated Loan Agreement, dated as of March 22, 2022, by and among Collegium Pharmaceutical, Inc., the... (Filed With SEC on February 23, 2023)

Indenture, dated as of February 10, 2023, between Collegium Pharmaceutical, Inc. and The Bank of New York Mellon Trust Company, N.A., as trustee (Filed With SEC on February 13, 2023)

Amendment to Employment Agreement, dated January 20, 2022 by and between Collegium Pharmaceutical, Inc. and Joseph Ciaffoni (Filed With SEC on May 10, 2022)

Amendment to Employment Agreement, dated January 20, 2022 by and between Collegium Pharmaceutical, Inc. and Colleen Tupper (Filed With SEC on May 10, 2022)

Amendment to Employment Agreement, dated January 20, 2022 by and between Collegium Pharmaceutical, Inc. and Shirley Kuhlmann (Filed With SEC on May 10, 2022)

Amendment to Employment Agreement, dated January 20, 2022 by and between Collegium Pharmaceutical, Inc. and Scott Dreyer (Filed With SEC on May 10, 2022)

Employment Agreement, dated March 23, 2022 by and between Collegium Pharmaceutical, Inc. and Thomas Smith (Filed With SEC on May 10, 2022)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 24, 2022)

Agreement and Plan of Merger, dated as of February 14, 2022, by and among Collegium Pharmaceutical, Inc., Bristol Acquisition Company Inc. and BioDelivery Sciences International,... (Filed With SEC on February 14, 2022)

Form of Tender and Support Agreement, dated as of February 14, 2022, by and among Collegium Pharmaceutical, Inc., Bristol Acquisition Company Inc. and certain stockholders of... (Filed With SEC on February 14, 2022)

Employment Agreement, dated May 24, 2021, by and between Colleen Tupper and Collegium Pharmaceutical, Inc (Filed With SEC on August 5, 2021)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 25, 2021)

Amended & Restated Employment Agreement, dated December 27, 2020, by and between Collegium Pharmaceutical, Inc. and Joseph Ciaffoni (Filed With SEC on December 30, 2020)

Amended & Restated Employment Agreement, dated December 28, 2020, by and between Collegium Pharmaceutical, Inc. and Paul Brannelly (Filed With SEC on December 30, 2020)

Amended & Restated Employment Agreement, dated December 27, 2020, by and between Collegium Pharmaceutical, Inc. and Scott Dreyer (Filed With SEC on December 30, 2020)

Amended & Restated Employment Agreement, dated December 29, 2020, by and between Collegium Pharmaceutical, Inc. and Alison B. Fleming, Ph.D (Filed With SEC on December 30, 2020)

Amended & Restated Employment Agreement, dated December 27, 2020, by and between Collegium Pharmaceutical, Inc. and Shirley Kuhlmann (Filed With SEC on December 30, 2020)

Amended & Restated Employment Agreement, dated December 27, 2020, by and between Collegium Pharmaceutical, Inc. and Richard Malamut, M.D (Filed With SEC on December 30, 2020)

Settlement Agreement, dated September 29, 2020, by and among Collegium Pharmaceutical, Inc. and Teva Pharmaceuticals USA, Inc (Filed With SEC on September 30, 2020)

Second Amendment to Loan Agreement, dated as of May 27, 2020, by and among the Company, Collegium Securities Corporation, BioPharma Credit PLC, as collateral agent, BPCR Limited... (Filed With SEC on August 5, 2020)

First Amendment to Loan Agreement, dated as of February 24, 2020, by and among the Company, its subsidiaries, BioPharma Credit PLC, as collateral agent and lender, and BioPharma... (Filed With SEC on May 7, 2020)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 27, 2020)

Underwriting Agreement, dated as of February 10, 2020, between Collegium Pharmaceutical, Inc. and Jefferies LLC (Filed With SEC on February 13, 2020)

Indenture, dated as of February 13, 2020, between Collegium Pharmaceutical, Inc. and The Bank of New York Mellon Trust Company, N.A., as trustee (Filed With SEC on February 13, 2020)

First Supplemental Indenture, dated as of February 13, 2020, between Collegium Pharmaceutical, Inc. and The Bank of New York Mellon Trust Company, N.A., as trustee (Filed With SEC on February 13, 2020)

Purchase Agreement, dated as of February 6, 2020, by and between Collegium Pharmaceutical, Inc. and Assertio Therapeutics, Inc (Filed With SEC on February 10, 2020)

Loan Agreement, dated as of February 6, 2020, by and among the Company, its subsidiaries, BioPharma Credit PLC, as collateral agent and lender, and BioPharma Credit Investments V... (Filed With SEC on February 10, 2020)

Employment Agreement, effective as of April 1, 2019, by and between Richard Malamut and Collegium Pharmaceutical, Inc (Filed With SEC on May 8, 2019)

Employment Agreement, effective as of August 4, 2015, by and between Alison Fleming and Collegium Pharmaceutical, Inc (Filed With SEC on May 8, 2019)

Form of Performance Share Unit Agreement under the Amended and Restated 2014 Stock Incentive Plan (Filed With SEC on May 8, 2019)

Second Amendment, dated August 29, 2018, to Commercialization Agreement by and among Assertio Therapeutics, Inc. and Collegium Pharmaceutical, Inc. and Collegium NF, LLC (Filed With SEC on November 8, 2018)

Second Amendment, dated October 19, 2018, to Lease by and between Park at 95, LLC and Collegium Pharmaceutical, Inc (Filed With SEC on November 8, 2018)

Amended and Restated Loan and Security Agreement, dated November 1, 2018, by and between Silicon Valley Bank and Collegium Pharmaceutical, Inc (Filed With SEC on November 8, 2018)

Warrant, issued November 8, 2018 (Filed With SEC on November 8, 2018)

Amendment No. 3 to Commercialization Agreement, dated November 8, 2018, by and among Collegium Pharmaceutical, Inc., Collegium NF, LLC, and Assertio Therapeutics, Inc (Filed With SEC on November 8, 2018)

Employment Agreement, dated July 10, 2018, by and between Collegium Pharmaceutical, Inc. and Scott Dreyer (Filed With SEC on August 8, 2018)

Amendment to Employment Agreement, dated June 4, 2018, by and between Collegium Pharmaceutical, Inc. and Joseph Ciaffoni (Filed With SEC on June 4, 2018)

Letter Agreement, dated June 4, 2018, by and between Collegium Pharmaceutical, Inc. and Michael T. Heffernan (Filed With SEC on June 4, 2018)

Office Lease agreement by and between Campanelli-Trigate 100 TCD Stoughton, LLC, and Collegium Pharmaceutical, Inc as of March 23, 2018 (Filed With SEC on May 9, 2018)

Employment Agreement, effective as of March 16, 2018, by and between Shirley Kuhlmann and Collegium Pharmaceutical, Inc (Filed With SEC on May 9, 2018)

Seventh Amendment to Loan and Security Agreement, dated March 30, 2018, by and between Silicon Valley Bank and Collegium Pharmaceutical, Inc (Filed With SEC on May 9, 2018)

Consent and Sixth Amendment to Loan and Security Agreement, dated January 9, 2018, by and between Collegium Pharmaceutical, Inc. and Silicon Valley Bank (Filed With SEC on January 10, 2018)

EMPLOYMENT AGREEMENT (Filed With SEC on May 31, 2017)

Collegium Pharmaceutical, Inc. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement (Filed With SEC on March 13, 2017)

5,000,000 Shares Collegium Pharmaceutical, Inc. UNDERWRITING AGREEMENT (Filed With SEC on October 27, 2016)

LICENSE AND DEVELOPMENT AGREEMENT (Filed With SEC on August 11, 2016)

EMPLOYMENT AGREEMENT (Filed With SEC on January 4, 2016)

[ ] Collegium Pharmaceutical, Inc. UNDERWRITING AGREEMENT (Filed With SEC on January 4, 2016)

EMPLOYMENT AGREEMENT (Filed With SEC on August 12, 2015)

EMPLOYMENT AGREEMENT (Filed With SEC on August 10, 2015)

[ ] Collegium Pharmaceutical, Inc. UNDERWRITING AGREEMENT(1) (Filed With SEC on April 27, 2015)

COLLEGIUM PHARMACEUTICAL, INC. 2015 EMPLOYEE STOCK PURCHASE PLAN (Filed With SEC on April 27, 2015)

COLLEGIUM PHARMACEUTICAL, INC. PERFORMANCE BONUS PLAN (Filed With SEC on April 27, 2015)

COLLEGIUM PHARMACEUTICAL, INC. AMENDED AND RESTATED 2014 STOCK INCENTIVE PLAN (Filed With SEC on April 27, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Restricted Stock Award Agreement (Filed With SEC on April 27, 2015)

INDEMNITY AGREEMENT (Filed With SEC on April 27, 2015)

AGREEMENT AND PLAN OF MERGER (Filed With SEC on April 2, 2015)

CONVERTIBLE PROMISSORY NOTE (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. SEVENTH AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. EIGHTH AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (Filed With SEC on April 2, 2015)

PREFERRED SHAREHOLDER AGREEMENT (Filed With SEC on April 2, 2015)

WARRANT TO PURCHASE STOCK (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. AMENDMENT NO. 1 TO THE SIXTH AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (Filed With SEC on April 2, 2015)

780 DEDHAM STREET CANTON, MASSACHUSETTS OFFICE LEASE AGREEMENT BETWEEN 780 DEDHAM STREET HOLDINGS, LLC (LANDLORD) AND COLLEGIUM PHARMACEUTICAL, INC. (TENANT) (Filed With SEC on April 2, 2015)

LOAN AND SECURITY AGREEMENT (Filed With SEC on April 2, 2015)

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT (Filed With SEC on April 2, 2015)

ASSUMPTION AND SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT (Filed With SEC on April 2, 2015)

THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT (Filed With SEC on April 2, 2015)

FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Series B Convertible Preferred Stock Purchase Agreement Dated as of February10, 2012 (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Series C Convertible Preferred Stock Purchase Agreement Dated as of August 27, 2013 (Filed With SEC on April 2, 2015)

AMENDMENT NO. 1 TO SERIES C CONVERTIBLE PREFERRED STOCK PURCHASE AGREEMENT (Filed With SEC on April 2, 2015)

CONVERTIBLE NOTE PURCHASE AGREEMENT (Filed With SEC on April 2, 2015)

SUBORDINATION AGREEMENT (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Restricted Stock Award Agreement Under 2012 Stock Incentive Plan (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. 2014 STOCK INCENTIVE PLAN (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Incentive Stock Option Agreement Under 2014 Stock Incentive Plan (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Non-Statutory Stock Option Agreement Under 2014 Stock Incentive Plan (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Incentive Stock Option Agreement Under 2014 Stock Incentive Plan (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Non-Statutory Stock Option Agreement Under 2014 Stock Incentive Plan (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. INCENTIVE STOCK OPTION AGREEMENT (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. NON-STATUTORY STOCK OPTION AGREEMENT (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. INDEMNIFICATION AGREEMENT (Filed With SEC on April 2, 2015)

SCHEDULE OF MATERIAL DIFFERENCES TO EXHIBIT 10.22 Name Boston Millennia Partners II Limited Partnership Boston Millennia Partners II-A Limited Partnership Boston Millennia... (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. CONFIDENTIALITY AND INVENTIONS AGREEMENT (Filed With SEC on April 2, 2015)

Confidential Offer Letter (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. TRANSACTION BONUS PLAN (Filed With SEC on April 2, 2015)

Collegium Pharmaceutical, Inc. Noncompetition, Confidentiality and Inventions Agreement (Filed With SEC on April 2, 2015)

CONFIDENTIAL (Filed With SEC on April 2, 2015)

| 780 Dedham Street, Suite 800 Canton, MA 02021 | tel ###-###-#### | fax ###-###-#### | (Filed With SEC on April 2, 2015)

COLLEGIUM PHARMACEUTICAL, INC. Series D Convertible Preferred Stock Purchase Agreement Dated as of March 6, 2015 (Filed With SEC on April 2, 2015)

FIRST AMENDMENT TO LEASE (Filed With SEC on April 2, 2015)

Confidential Offer Letter (Filed With SEC on April 2, 2015)

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COLLEGIUM PHARMACEUTICAL, INC Contracts & Agreements