ARQULE INC | Business Contracts

First Amendment to Agreement and Plan of Merger, dated December 17, 2019, among ArQule, Inc., Merck Sharp & Dohme Corp. and Argon Merger Sub, Inc (Filed With SEC on December 17, 2019)

1.1Underwriting Agreement dated June 24, 2019 (Filed With SEC on June 25, 2019)

Separation of Employment Agreement, dated March 13, 2019, between the Company and Robert Weiskopf (Filed With SEC on May 1, 2019)

Form of Non-Statutory Stock Option Agreement to the Companys 2014 Equity Incentives Plan (Filed With SEC on March 7, 2019)

Agreement and Plan of Merger, dated December 6, 2019, among ArQule, Inc., Merck Sharp & Dohme Corp. and Argon Merger Sub, Inc (Filed With SEC on December 9, 2019)

Fifth Amendment to Employment Agreement, dated as of March 29, by and between the Company and Paolo Pucci (Filed With SEC on May 1, 2019)

Sixth Amendment to Employment Agreement, dated as of March 29, by and between the Company and Peter S. Lawrence (Filed With SEC on May 1, 2019)

Sixth Amendment to Employment Agreement, dated as of March 29, by and between the Company and Brian Schwartz (Filed With SEC on May 1, 2019)

Letter Agreement, dated April 11, 2019, by and between the Company and Marc Schegerin (Filed With SEC on May 1, 2019)

Form of Incentive Stock Option Agreement to the Companys 2014 Equity Incentives Plan (Filed With SEC on March 7, 2019)

ARQULE INC (10)