TG THERAPEUTICS, INC. Contracts & Agreements

Master Services Agreement between FUJIFILM DIOSYNTH BIOTECHNOLOGIES NORTH CAROLINA, INC, FUJIFILM DIOSYNTH BIOTECHNOLOGIES DENMARK APS and TG Therapeutics, Inc., effective October... (Filed With SEC on November 7, 2024)

Amendment to the TG Therapeutics, Inc. 2022 Incentive Plan (Filed With SEC on June 17, 2024)

License Agreement, dated January 7, 2024, by and between TG Therapeutics, Inc., TG Cell Therapy, Inc., and Precision BioSciences, Inc (Filed With SEC on February 29, 2024)

Commercialization Agreement by and between TG Therapeutics, Inc. and Neuraxpharm Pharmaceuticals, S.L., dated as of July 28, 2023 (Filed With SEC on August 4, 2023)

First Amendment to Amended and Restated Loan and Security Agreement, dated March 31, 2023, by and among TG Therapeutics, Inc., TG Biologics, Inc. and Hercules Capital, Inc (Filed With SEC on May 8, 2023)

Amended and Restated Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Capital Inc (Filed With SEC on May 8, 2023)

Amended and Restated Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Funding IV, LLC (Filed With SEC on May 8, 2023)

Amended and Restated Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Private Credit Fund 1 L.P (Filed With SEC on May 8, 2023)

Amended and Restated Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Private Global Venture Growth Fund I L.P (Filed With SEC on May 8, 2023)

Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Capital Inc (Filed With SEC on May 8, 2023)

Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Private Credit Fund 1 L.P (Filed With SEC on May 8, 2023)

Warrant Agreement, dated March 31, 2023, by and between TG Therapeutics, Inc. and Hercules Private Global Venture Growth Fund I L.P (Filed With SEC on May 8, 2023)

TG Therapeutics, Inc. 2022 Incentive Plan (Filed With SEC on June 23, 2022)

Amended and Restated Loan and Security Agreement, dated December 30, 2021, by and among TG Therapeutics, Inc., TG Biologics, Inc. and Hercules Capital, Inc (Filed With SEC on March 1, 2022)

Warrant Agreement, dated December 30, 2021, by and between TG Therapeutics, Inc. and Hercules Capital Inc (Filed With SEC on March 1, 2022)

Warrant Agreement, dated December 30, 2021, by and between TG Therapeutics, Inc. and Hercules Private Credit Fund I L.P (Filed With SEC on March 1, 2022)

Warrant Agreement, dated December 30, 2021, by and between TG Therapeutics, Inc. and Hercules Private Global Venture Growth Fund I L.P (Filed With SEC on March 1, 2022)

Amended and Restated Employment Agreement by and between TG Therapeutics, Inc. and Michael S. Weiss, dated June 18, 2021 (Filed With SEC on August 6, 2021)

Description of Securities of TG Therapeutics, Inc (Filed With SEC on March 1, 2021)

Underwriting Agreement, dated December 14, 2020, by and among TG Therapeutics, Inc. and J.P. Morgan Securities LLC, Goldman Sachs & Co. LLC, Evercore Group L.L.C. and Cantor... (Filed With SEC on December 16, 2020)

Amendment to TG Therapeutics, Inc. Amended and Restated 2012 Incentive Plan (Filed With SEC on June 24, 2020)

Underwriting Agreement, dated May 14, 2020, by and among TG Therapeutics, Inc. and J.P. Morgan Securities LLC, Jefferies LLC, Evercore Group L.L.C. and Cantor Fitzgerald & Co., as... (Filed With SEC on May 18, 2020)

At Market Issuance Sales Agreement, among the Company and Jefferies LLC, Cantor Fitzgerald & Co. and B. Riley FBR, Inc., dated March 20, 2020 (Filed With SEC on March 20, 2020)

Description of Securities of TG Therapeutics, Inc (Filed With SEC on March 2, 2020)

Master Services Agreement between Samsung Biologics Co., Ltd. and TG Therapeutics, Inc., effective February 21, 2018 (Filed With SEC on August 9, 2019)

Amended and Restated Collaboration Agreement by and between TG Therapeutics, Inc. and Checkpoint Therapeutics, Inc., dated June 19, 2019 (Filed With SEC on August 9, 2019)

Underwriting Agreement, dated March 1, 2019, by and between TG Therapeutics, Inc. and Cantor Fitzgerald & Co (Filed With SEC on March 5, 2019)

Warrant Agreement, dated February 28, 2019, by and between TG Therapeutics, Inc. and Hercules Capital, Inc (Filed With SEC on March 5, 2019)

Warrant Agreement, dated February 28, 2019, by and between TG Therapeutics, Inc. and Hercules Technology III, L.P (Filed With SEC on March 5, 2019)

Loan and Security Agreement, dated February 28, 2019, by and among TG Therapeutics, Inc., TG Biologics, Inc. and Hercules Capital, Inc (Filed With SEC on March 5, 2019)

Master Services Agreement, effective February 21, 2018 (Filed With SEC on March 1, 2019)

License Agreement between TG Therapeutics, Inc. and Novimmune S.A., dated June 18, 2018 (Filed With SEC on August 9, 2018)

License Agreement between TG Therapeutics, Inc. and Jiangsu Hengrui Medicine Co., dated January 8, 2018 (Filed With SEC on March 15, 2018)

UNDERWRITING AGREEMENT between TG THERAPEUTICS, INC. and JEFFERIES LLC as Representative of the Several Underwriters (Filed With SEC on March 9, 2017)

SUBLICENSE AGREEMENT (Filed With SEC on August 9, 2016)

CollaborationAGREEMENT (Filed With SEC on May 11, 2015)

LICENSINGAGREEMENT BYAND BETWEEN TGTHERAPEUTICS, INC. AND RHIZENPHARMACEUTICALS S A (Filed With SEC on January 20, 2015)

AMENDMENT TO RESTRICTED STOCK SUBSCRIPTIONAGREEMENTS (Filed With SEC on January 7, 2015)

AMENDMENT TO RESTRICTED STOCK SUBSCRIPTIONAGREEMENT (Filed With SEC on November 14, 2014)

LICENSINGAGREEMENT BYAND BETWEEN TGTHERAPEUTICS, INC. AND RHIZENPHARMACEUTICALS S A (Filed With SEC on November 14, 2014)

LICENSEAGREEMENT Dated as of June 23, 2014 by and between Ligand Pharmaceuticals Incorporated and TG Therapeutics, Inc. (Filed With SEC on July 24, 2014)

STOCKHOLDER PROTECTION RIGHTS AGREEMENT dated as of July 18, 2014 between TG THERAPEUTICS, INC. and AMERICAN STOCK TRANSFER & TRUST COMPANY,LLC as Rights Agent (Filed With SEC on July 21, 2014)

AMENDMENT TO RESTRICTED STOCK SUBSCRIPTIONAGREEMENT (Filed With SEC on November 15, 2013)

Alston&Birdllp 90 Park Avenue New York, NY 10016 ###-###-#### Fax ###-###-#### www.alston.com July 23, 2013 (Filed With SEC on July 23, 2013)

AMENDMENT TO RESTRICTED STOCK AGREEMENT (Filed With SEC on July 16, 2013)

TG THERAPEUTICS, INC. Common Stock (par value $0.001 per share) At-the-Market Issuance Sales Agreement (Filed With SEC on June 21, 2013)

SUBLICENSE AGREEMENT By AndBetween TGBIOLOGICS, INC. And ILDONG PHARMACEUTICAL CO. LTD. November 13, 2012 CONFIDENTIAL (Filed With SEC on March 21, 2013)

JOINTVENTURE AND LICENSE OPTION AGREEMENT BYAND BETWEEN TGTHERAPEUTICS, INC. AND RHIZENPHARMACEUTICALS S A (Filed With SEC on November 14, 2012)

COMMON STOCK PURCHASE WARRANT (Filed With SEC on November 13, 2012)

SECURITIES EXCHANGE AGREEMENT (Filed With SEC on November 13, 2012)

AMENDMENT NO. 1 TO EXCHANGE TRANSACTION AGREEMENT (Filed With SEC on August 8, 2012)

RESTRICTED STOCK SUBSCRIPTION AGREEMENT (Filed With SEC on March 14, 2012)

EMPLOYMENT AGREEMENT (Filed With SEC on March 14, 2012)

RESTRICTED STOCK SUBSCRIPTION AGREEMENT (Filed With SEC on March 14, 2012)

EMPLOYMENT AGREEMENT (Filed With SEC on March 14, 2012)

WARRANT TO PURCHASE COMMON STOCK OF Manhattan Pharmaceuticals, Inc. (Filed With SEC on March 14, 2012)

EXCLUSIVE LICENSE AGREEMENT BY AND AMONG GTCBIOTHERAPEUTICS, INC., LFBBIOTECHNOLOGIES S.A.S., LFB/GTCLLC and TG THERAPEUTICS, INC. January, 30th , 2012 CONFIDENTIAL (Filed With SEC on March 14, 2012)

EXCHANGE TRANSACTION AGREEMENT (Filed With SEC on January 5, 2012)

By:Swiss Pharma Contract Ltd. S:/ Dr. Rob Aspbury Dr. Rob Aspbury Encls. (Filed With SEC on December 19, 2011)

ARISTON PHARMACEUTICALS, INC. Amended and Restated Convertible Promissory Note (Filed With SEC on March 7, 2011)

WAIVERAND FORBEARANCE AGREEMENT (Filed With SEC on February 14, 2011)

SETTLEMENT AND RELEASEAGREEMENT (Filed With SEC on January 10, 2011)

MANHATTANPHARMACEUTICALS, INC. FORM OFWARRANT (Filed With SEC on November 3, 2009)

MANHATTANPHARMACEUTICALS, INC. SUBSCRIPTIONAGREEMENT (Filed With SEC on November 3, 2009)

MANHATTANPHARMACEUTICALS, INC. 12% Original Issue DiscountSenior Subordinated Convertible Debenture (Filed With SEC on November 3, 2009)

MANHATTANPHARMACEUTICALS, INC. WARRANT (Filed With SEC on November 3, 2009)

AMENDMENTNO. 1 TO REGISTRATIONRIGHTS AGREEMENT (Filed With SEC on April 10, 2009)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on November 25, 2008)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on November 25, 2008)

SECURITY AGREEMENT (Filed With SEC on November 25, 2008)

DEFAULT AGREEMENT (Filed With SEC on November 25, 2008)

MANHATTAN PHARMACEUTICALS, INC. 12% Senior Secured Promissory Note (Filed With SEC on November 25, 2008)

MANHATTAN PHARMACEUTICALS, INC. FORM OF WARRANT (Filed With SEC on November 25, 2008)

AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT (Filed With SEC on November 25, 2008)

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT (Filed With SEC on November 25, 2008)

MANHATTAN PHARMACEUTICALS, INC. FORM OF WARRANT (Filed With SEC on November 25, 2008)

JOINT VENTURE AGREEMENT (Filed With SEC on October 3, 2008)

OMNIBUS AMENDMENT TO JOINT VENTURE AGREEMENT AND ADDITIONAL AGREEMENTS (Filed With SEC on October 3, 2008)

Manhattan Pharmaceuticals, Inc. 810 Seventh Avenue, 4th Floor New York, New York 10019 September 17, 2008 (Filed With SEC on October 3, 2008)

MANHATTAN PHARMACEUTICALS, INC. Warrant for the Purchase of Shares of Common Stock (Filed With SEC on September 15, 2008)

SECURED PROMISSORY NOTE (Filed With SEC on September 15, 2008)

OMNIBUS AMENDMENT TO JOINT VENTURE AGREEMENT AND ADDITIONAL AGREEMENTS (Filed With SEC on June 13, 2008)

MANHATTAN PHARMACEUTICALS, INC. Warrant for the Purchase of Shares of Common Stock (Filed With SEC on May 1, 2008)

AMENDMENT TO EMPLOYMENT AGREEMENT BY AND BETWEEN MANHATTAN PHARMACEUTICALS, INC. AND DOUGLAS ABEL (Filed With SEC on March 31, 2008)

ASSIGNMENT AND CONTRIBUTION AGREEMENT (Filed With SEC on March 31, 2008)

JOINT VENTURE AGREEMENT (Filed With SEC on March 31, 2008)

SEPARATION AND RELEASE AGREEMENT (Filed With SEC on March 31, 2008)

MANHATTAN PHARMACEUTICALS, INC. 2003 STOCK OPTION PLAN (as amended through May 24, 2007) (Filed With SEC on May 31, 2007)

MANHATTAN PHARMACEUTICALS, INC. Warrant for the Purchase of Shares of Common Stock No. 2007PBI-1 509,275Shares (Filed With SEC on April 5, 2007)

SUBSCRIPTION AGREEMENT (Filed With SEC on April 5, 2007)

MANHATTAN PHARMACEUTICALS, INC. Warrant for the Purchase of Shares of Common Stock (Filed With SEC on April 5, 2007)

Manhattan Pharmaceuticals, Inc. Non-employee Director Compensation Arrangement (Filed With SEC on February 5, 2007)

Manhattan Pharmaceuticals, Inc. 810 Seventh Avenue, 4th Floor New York, NY 10019 (Filed With SEC on July 12, 2006)

EMPLOYMENT AGREEMENT (Filed With SEC on July 12, 2006)

SUBSCRIPTION AGREEMENT (Filed With SEC on September 1, 2005)

MANHATTAN PHARMACEUTICALS, INC. Warrant for the Purchase of Shares of Common Stock No. [ ] ______Shares (Filed With SEC on September 1, 2005)

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TG THERAPEUTICS, INC. Contracts & Agreements