Statement of Work dated January 21, 2022 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW P-10558-01

Exhibit 10.30

[***] = CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS, HAS BEEN OMITTED BECAUSE THE INFORMATION (I) IS NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED.

EXHIBIT A

Scope of Work (SOW)

Scope of Work

P-10558-01

Scope of Work for Cleanroom 3 Use and Customization/Expansion of Cleanroom Space

(January 1^st, 2022 to March 31^st 2023)

P:01532524.1:74232.001

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Section 1 - Background/Scope

Azzur Cleanrooms On Demand (“COD”) facilities are designed for clients to utilize controlled clean areas and services related to early phase cGMP manufacturing. This Scope of Work (“SOW”) is for 15 months, subject to terms and conditions specified in the LICENSE AND SERVICES AGREEMENT, of cleanroom use (“CR3”) and support related services at the COD facility located at 411 Waverley Oaks Rd., #126, Waltham, MA 02452.  This SOW replaces P-9717 for the duration of January 2022 to March 2023.  This SOW is entered into by and COD (“Licensor”) and Synlogic (“Licensee”) effective as of the approval date of this SOW. Upon execution of this SOW, this SOW will be incorporated into a mutually approved License and Services Agreement (“LSA”) that contains additional terms and conditions of the COD Cleanrooms and support services use.

A Purchase Order (“PO”) for the license fees for the duration of 15 months and the first monthly pre-payment of the license fees, as identified this SOW, will be due no later than 30 days after the execution of this SOW and the related LSA.

Section 2 – License and Technical Requirements

Commencing on the Effective Date and subject to the terms and conditions of the LSA, Licensor grants to Licensee a license to access and use the cleanroom with specification described in Section 3. Licensor will provide the support services described in this Section 3 using Licensor personnel. Licensor personnel will perform the services in a timely, professional and workmanlike manner and in accordance with all applicable laws, regulations and guidelines. Licensor will maintain all permits, licenses or other approvals necessary for the operation of the Cleanroom in accordance with the requirements set forth herein. Specifically, Licensor will perform Services in accordance with the following:

Licensor personnel will be experienced with FDA facility compliance expectations. Licensor has based this Statement of Work upon the following documents.

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Licensee personnel using the classified areas are to be trained on Licensor SOPs on gowning, personnel movement, material control, gowning training, safety training etc.

Section 3 – Detailed Scope

This SOW provides details of the licensed cleanroom space, office space, support services and the related inclusions.

Remote alarm management is performed by Licensor.

NOTE: BSC cleaning and disinfection during routine use is Licensee’s responsibility.

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NOTE: Changes in cleaning regimen including type of agents and frequency as well as enhanced cleaning for changeover can be implemented, the costs for which are not included in this SOW.

NOTE: Changes in environmental monitoring including additional in-process monitoring costs are included in Table 4 of this SOW.

* Client [***] will not be powered by the Back-Up Emergency Power Generators.

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Section 4 – Fees

The License Fee will be pre-paid on a monthly basis and includes items listed under the relevant category in Table 1 below. A monthly Variable Budget for support services overage compared to SMU amounts and out of scope activities has been established at $[***] per month. Specifically, the variable budget will cover the following known items, as needed:

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Table 4 below shows the costs related to support services for monthly overages and other services to be covered by the Variable Budget, if required. Note that the unit costs of overages are higher than unit costs included in the License Fees as unplanned activities result in additional costs such as offsite storage, material movement and personnel time.

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COD (“Licensor”)  has agreed to perform facility customizations upgrades on behalf of Synlogic (“Licensee”)

for $650,000.00. [***]% Payment upon agreement and [***]% payment upon turnover of the completed space, subject to Section 6, below.

Facility Customization project and Payment Terms will be outlined in separate scope of work P-10558-02.

Section 5 – Payments and Invoicing

All invoices are due net +30 days from the invoice date. Fixed amounts for the monthly License Fee   will be generated at the start of each month. Monthly invoices for variable amounts will be generated out at the end of each month, if required based on actual usage.

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The total amount for CR3 use and related services for 15 months starting January 2022 to March 2023 is $2,271,699.  In addition, the variable budget of $[***]/month, total amount $150,000 will also be required.  A Purchase Order (“PO”) for the total amount is required for the reservation of the cleanroom and related services specified in this SOW.

Section 6 – Timing

In accordance with the facility customization and build-out schedule (“Facility Customization”) in Appendix 1, COD shall complete Facility Customization no later than [***].  COD acknowledges and agrees that time is of the essence in the completion of the Facility Customization. COD shall use its best efforts to ensure that Facility Customization is completed by [***], and represents and warrants that it is not aware of any fact or circumstance that would delay completion of Facility Customization after this date.  [***].

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Section 7 – Approvals

SOW Generated by (COD):

/s/ Joseph Sollecito

Date: 21JAN2022

Name: Joseph Sollecito, Senior Director Azzur Cleanrooms on Demand-Boston

Email: ***@***

SOW Accepted by (Synlogic):

/s/ Gregg Beloff

NAME:  Gregg Beloff

TITLE: Chief Financial Officer

DATE: 1/21/22

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Appendix 1 – Facility Customization Schedule:

[***]

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