Addendum to Statement of Work dated December 8, 2023 pursuant to Master Contract Services Agreement between Synlogic, Inc. and Azzur Group (d/b/a Azzur of New England LLC), SOW P-10558-01 Addendum

To: Synlogic OperatingCompany, Inc. CR3 License Fee, SOW P-10558-01

From: Azzur Cleanrooms on Demand, Waltham
Re: Addendum to Scope of Work for Cleanroom 3 Use, SOW P-10558-01

Synlogic Operating Company, Inc. (“Synlogic”) has notified Azzur Cleanrooms on Demand (“Azzur”) that it shall be exercising its First and Second Option to extend its use of Azzur facilities until December 31, 2024. The purpose of this addendum is to outline the 2024 License fee term for Synlogic Operating Company, Inc. and to confirm that the Addendum includes additional Ambient storage, Personnel hours and BSC sampling once a week. All other terms remain the same.

Please refer to Table 1 for additional information

Table 1: License Fee 2024