SYNERGY PHARMACEUTICALS, INC. Contracts & Agreements

Amended and Restated Asset Purchase Agreement by and among, Synergy Pharmaceuticals Inc., Synergy Advanced Pharmaceuticals, Inc., Bausch Health Companies Inc. and Bausch Health... (Filed With SEC on January 10, 2019)

Asset Purchase Agreement by and among, Synergy Pharmaceuticals Inc., Synergy Advanced Pharmaceuticals, Inc., Bausch Health Companies Inc. and Bausch Health Ireland Limited, dated... (Filed With SEC on December 13, 2018)

Term Sheet, dated December 11, 2018, by and between Synergy Pharmaceuticals Inc. and CRG Servicing, LLC (Filed With SEC on December 13, 2018)

Amendment to Limited Forbearance Agreement, dated as of December 5, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative... (Filed With SEC on December 6, 2018)

Limited Forbearance Agreement, dated as of November 21, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative agent and... (Filed With SEC on November 26, 2018)

Amendment and Waiver No. 6, dated as of November 16, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative agent and... (Filed With SEC on November 19, 2018)

Amendment and Waiver No. 5, dated as of November 13, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative agent and... (Filed With SEC on November 14, 2018)

Separation Agreement dated September 17, 2018 by and between Marino Garcia and Synergy Pharmaceuticals Inc (Filed With SEC on November 9, 2018)

Separation Agreement dated October 30, 2018 by and between Gary S. Jacob and Synergy Pharmaceuticals Inc (Filed With SEC on November 9, 2018)

License, Development and Commercialization Agreement dated as of August 3, 2018 by and between Synergy Pharmaceuticals Inc. and Shandong Luoxin Pharmaceutical Group Stock Co., Ltd (Filed With SEC on November 9, 2018)

Waiver No. 4, dated as of November 6, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative agent and collateral agent and... (Filed With SEC on November 6, 2018)

Amendment and Waiver No. 3, dated as of October 30, 2018, among Synergy Pharmaceuticals Inc., certain of its subsidiaries, CRG Servicing LLC, as administrative agent and... (Filed With SEC on October 31, 2018)

Amendment No. 2 to Term Loan Agreement, dated August 28, 2018, among Synergy Pharmaceuticals Inc., the Subsidiary Guarantors as from time to time party hereto, the Lenders listed... (Filed With SEC on August 31, 2018)

Form of Waiver No 2 dated as of June 12, 2018 (Filed With SEC on June 13, 2018)

Executive Employment Agreement dated as of December 22, 2017 between Synergy Pharmaceuticals Inc. and Troy Hamilton (Filed With SEC on March 1, 2018)

Seventh Amended Executive Employment Agreement dated the 18th day of December 2017 by and between Synergy Pharmaceuticals Inc. and Gary S. Jacob, Ph.D (Filed With SEC on March 1, 2018)

Amendment No. 1 dated as of February 26, 2018 to Term Loan Agreement dated as of September 1, 2017 between Synergy Pharmaceuticals Inc. and CRG Servicing LLC (Filed With SEC on March 1, 2018)

Underwriting Agreement by and between Synergy Pharmaceuticals Inc. and Jefferies LLC, as representative of the several underwriters, dated November 13, 2017 (Filed With SEC on November 15, 2017)

Form of Warrant Agency Agreement (including the form of Warrant certificate) (Filed With SEC on November 15, 2017)

SEPARATION AND RELEASE AGREEMENT (Filed With SEC on May 26, 2017)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on April 17, 2017)

SYNERGY PHARMACEUTICALS INC. AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of February 28, 2017 to Indenture Dated as of November3,... (Filed With SEC on March 1, 2017)

FIFTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 1, 2017)

20,325,204 Shares SYNERGY PHARMACEUTICALS INC. Common Stock UNDERWRITING AGREEMENT (Filed With SEC on February 2, 2017)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on May 5, 2016)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on February 25, 2016)

WITNESSETH: (Filed With SEC on February 25, 2016)

AMENDMENT TO THIRD AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on February 25, 2016)

WITNESSETH: (Filed With SEC on February 25, 2016)

AMENDMENT TO FOURTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on January 22, 2016)

AMENDMENT TO FOURTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on January 21, 2016)

FOURTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 16, 2015)

THIRD AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 16, 2015)

AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 16, 2015)

SYNERGY PHARMACEUTICALS INC. AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of November 3, 2014 7.50% Convertible Senior Notes due 2019 (Filed With SEC on November 3, 2014)

SECOND AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on April 3, 2014)

SYNERGY PHARMACEUTICALS INC. CONTROLLED EQUITY OFFERINGSM AMENDMENT NO. 1 TO SALES AGREEMENT (Filed With SEC on March 5, 2014)

16,375,000 Shares SYNERGY PHARMACEUTICALS INC. Common Stock UNDERWRITING AGREEMENT (Filed With SEC on April 11, 2013)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 18, 2013)

CONSULTING AGREEMENT (Filed With SEC on March 18, 2013)

ASSET PURCHASE AGREEMENT between BRISTOL-MYERS SQUIBB COMPANY, and SYNERGY PHARMACEUTICALS, INC. Dated as of August 17, 2012 (Filed With SEC on March 18, 2013)

ASSET PURCHASE AGREEMENT between BRISTOL-MYERS SQUIBB COMPANY, and SYNERGY PHARMACEUTICALS, INC. Dated as of August 17, 2012 (Filed With SEC on October 25, 2012)

AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER (Filed With SEC on October 16, 2012)

AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on August 9, 2012)

AGREEMENT AND PLAN OF MERGER by and between SYNERGY PHARMACEUTICALS INC. and CALLISTO PHARMACEUTICALS, INC. Dated as of July 20, 2012 (Filed With SEC on July 23, 2012)

10,000,000 Shares of Common Stock SYNERGY PHARMACEUTICALS INC. UNDERWRITING AGREEMENT (Filed With SEC on May 4, 2012)

AGREEMENT AND PLAN OF MERGER (Filed With SEC on March 15, 2012)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on March 15, 2012)

AMENDED AND RESTATED SYNERGY PHARMACEUTICALS, INC. WARRANT AGENCY AGREEMENT (Filed With SEC on December 16, 2011)

AMENDED AND RESTATED SYNERGY PHARMACEUTICALS, INC. UNIT AGENCY AGREEMENT (Filed With SEC on December 16, 2011)

$15,000,000 of Units SYNERGY PHARMCEUTICALS, INC. Units Consisting of Two Shares of Common Stock and One Warrant to Purchase One Share of Common Stock UNDERWRITING AGREEMENT (Filed With SEC on December 1, 2011)

SYNERGY PHARMACEUTICALS, INC. WARRANT AGENCY AGREEMENT (Filed With SEC on December 1, 2011)

SYNERGY PHARMACEUTICALS, INC. UNIT AGENCY AGREEMENT (Filed With SEC on December 1, 2011)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. (Filed With SEC on November 15, 2011)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on November 15, 2011)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. (Filed With SEC on October 14, 2011)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on October 14, 2011)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. (Filed With SEC on October 6, 2011)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on October 6, 2011)

SYNERGY PHARMACEUTICALS, INC. SUBSCRIPTION AGREEMENT SECTION 1. (Filed With SEC on August 3, 2011)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. (Filed With SEC on May 6, 2011)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on May 6, 2011)

SECOND AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on May 6, 2011)

SECOND AMENDED AND RESTATED CONSULTING AGREEMENT (Filed With SEC on May 6, 2011)

SYNERGY PHARMACEUTICALS, INC. 17% Note Due: April 1, 2011 (Filed With SEC on March 16, 2011)

LOAN AGREEMENT (Filed With SEC on March 16, 2011)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. Warrant Shares: Initial Exercise Date: (Filed With SEC on March 10, 2011)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on March 10, 2011)

MASTERSERVICES AGREEMENT (CMCServices) (Filed With SEC on November 9, 2010)

MASTER SERVICES AGREEMENT (Filed With SEC on November 9, 2010)

COMMONSTOCK PURCHASE WARRANT SYNERGYPHARMACEUTICALS, INC. (Filed With SEC on October 5, 2010)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on October 5, 2010)

COMMON STOCK PURCHASE WARRANT SYNERGY PHARMACEUTICALS, INC. (Filed With SEC on July 7, 2010)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on July 7, 2010)

SYNERGY PHARMACEUTICALS, INC. 2009 DIRECTORS STOCK OPTION PLAN (Filed With SEC on March 15, 2010)

AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on February 5, 2010)

AMENDEDAND RESTATED CONSULTING AGREEMENT (Filed With SEC on February 5, 2010)

SYNERGY PHARMACEUTICALS, INC. SECURITIES PURCHASE AGREEMENT (Filed With SEC on November 5, 2009)

SYNERGYPHARMACEUTICALS, INC. SECURITIESPURCHASE AGREEMENT (Filed With SEC on August 14, 2009)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on April 15, 2009)

CONSULTING AGREEMENT (Filed With SEC on April 15, 2009)

EXCHANGE AGREEMENT (Filed With SEC on July 18, 2008)

PAWFECT FOODS, INC. 2008 EQUITY COMPENSATION INCENTIVE PLAN (Filed With SEC on July 18, 2008)

SYNERGY PHARMACEUTICALS INC. RESTRICTED STOCK PURCHASE AGREEMENT (Filed With SEC on July 18, 2008)

SYNERGYPHARMACEUTICALS INC. NON-STATUTORYSTOCK OPTION AGREEMENT (Filed With SEC on July 18, 2008)

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SYNERGY PHARMACEUTICALS, INC. Contracts & Agreements