Beau Standish Letter Agreement, dated May 22, 2021

STRICTLY CONFIDENTIAL

May 20, 2021

We are pleased to announce that as of May 20, 2021, SeaSpine Holdings Corporation (“SeaSpine,” which term, unless the context requires otherwise, includes all of SeaSpine’s affiliates, including its parent, subsidiary, and sibling companies, whether direct or indirect) will acquire your current employer 7D Surgical Inc.

In connection with the acquisition, and in exchange for the consideration below, including our one-time grant of a stock option award, we are pleased to extend you an offer to join SeaSpine as an employee of 7D Surgical ULC. Please note that it is a condition of employment that you review, accept, and sign SeaSpine’s Confidentiality, Invention Assignment & Restrictive Covenants Agreement, attached as Appendix A (the “Confidentiality Agreement”), and SeaSpine’s Dispute Resolution Agreement, attached as Appendix B (the “Dispute Resolution Agreement”). Please also note that your employment will be governed by and you must comply with SeaSpine’s policies and procedures, including the 7D Surgical Employee Handbook, effective January 1, 2021 (the “Employee Handbook”).

This letter, the Confidentiality Agreement, and the Dispute Resolution Agreement (collectively, the “Agreement”), as well as SeaSpine’s policies and procedures, including the Employee Handbook, will govern the terms and conditions of your employment, in accordance with all applicable legislation. Your modified terms of employment are outlined below.

EMPLOYER: 7D Surgical ULC

EFFECTIVE DATE: May 20, 2021

WORK LOCATION: Toronto, Ontario

TITLE: President, Enabling Technologies

MANAGER: Keith Valentine

President & CEO, SeaSpine

COMPENSATION: As an exempt (not eligible for overtime) employee, you will be paid a salary on a “salary basis.” Your gross annual base salary will be increased to CAD $340,000.00. This salary will be paid, less applicable deductions for income tax, as well as Canada Pension Plan and Employment Insurance remittances, in accordance with our standard payroll practices, which currently is bi-weekly.

ONE-TIME STOCK OPTION AWARD: We expect to grant you a nonqualified stock option award to purchase 100,000 shares of SeaSpine’s common stock (the calculated value of which is approximately USD $800,000.00), which option would, subject to your continued employment (as described below under “Active Employment”), vest as follows: 25% of the underlying shares would vest on January 1, 2023, with the remaining shares vesting in substantially equal quarterly installments over the following 12 quarters. We expect this award to be granted under one of our equity award plans following a meeting of SeaSpine’s Board of Directors, scheduled to take place on June 2, 2021. The exercise price will be the fair market value of SeaSpine’s common stock on the grant date. Your eligibility to receive any award is subject to your executing certain award-related documentation. You will receive additional grant information from the company’s equity plan administrator separately. SeaSpine reserves the right to amend its equity plan at any time.

BONUS PROGRAM: Your annual target under SeaSpine’s variable cash incentive award program for 2021 is 45% of your base salary. The general terms and conditions of the program are provided to you concurrently with this letter. In general, employees are eligible to participate in the program

provided employment begins before October 1 of the program year. Variable cash incentive awards will be prorated for eligible employees with a hire date on or after April 1 of the program year. Under this discretionary pay-for-performance program, payout of this incentive is subject to the company achieving its performance targets and you meeting your individual performance objectives. Employees must be employed with the company on the date the variable cash incentive award is paid to have earned and be eligible for the award. The terms and conditions of future incentive opportunities will be based on the company’s future circumstances. Any payment arising out of the above-noted bonus program is discretionary and not designed to be part of your regular compensation. SeaSpine reserves the right to amend its bonus program at any time.

TERMINATION: This Agreement, and therefore, your employment may be terminated as set forth below in full satisfaction of any claims that could be made in respect of such termination of employment, whether arising under statute, this contract of employment, or at common law. For clarity, if you are terminated from employment for any of the reasons below, your entitlements will be as set forth below, and you will have no entitlement to vesting or payments under SeaSpine’s above-noted equity plan(s) or bonus program(s), unless you are actively employed as set out above.

a.Resignation: You may voluntarily resign by providing SeaSpine two (2) weeks’ written notice, which may be waived in whole or in part at SeaSpine’s sole discretion, in which case you would be paid to the end of the two (2) weeks.

b.Wilful Misconduct, Disobedience, or Wilful Neglect of Duty: SeaSpine has the right, at any time, to terminate your employment under this Agreement without notice or pay in lieu thereof, or severance pay, in accordance with the Employment Standards Act, 2000 and applicable Regulation, in the event you engage in wilful misconduct, disobedience, or wilful neglect of duty that is not trivial and has not been condoned by SeaSpine. In the event your employment is terminated in accordance with this provision, you shall only receive any accrued but unpaid wages and vacation pay owed to you as of the date of termination.

c.Frustration of Contract: In the event of long term disability, your employment contract will be considered to be frustrated if you are not able to perform or fulfil the essential duties and requirements of your job, and there is no reasonable expectation that you will be able to do so in the foreseeable future. Any such frustration is subject to any required accommodation pursuant to the Human Rights Code to be provided by SeaSpine, and subject to all requirements of the Employment Standards Act, 2000, including, without limitation, benefits continuation, pension contributions, holiday eligibility (if applicable), and vacation pay accrual, along with pay in lieu of notice for the statutory notice period and severance pay (if any). You expressly understand and agree that, in the event of frustration, satisfaction of all requirements of the Employment Standards Act, 2000 will also satisfy any claims you could make under common law.

d.Without Cause: At its sole direction, SeaSpine may terminate your employment at any time, after successfully completing your probation (if applicable), without cause, on providing you with your entitlements under the Employment Standards Act, 2000, including any outstanding wages and notice or pay in lieu of notice and/or severance pay, less any applicable deductions. Any entitlements you would have under the Employment Standards Act, 2000 will continue for the statutory notice period, including, without limitation, benefits continuation, pension contributions, holiday eligibility, and vacation pay, where applicable. SeaSpine’s compliance with this clause and the Employment Standards Act, 2000 shall fully satisfy any of your statutory, contractual, and common law entitlements.

SEVERABILITY: In the event that any provision of this Agreement (including this letter, the Confidentiality Agreement, and the Dispute Resolution Agreement) is found to be void, invalid, illegal, or unenforceable, such finding will not affect any other provision of this Agreement (including this letter, the Confidentiality Agreement, and the Dispute Resolution Agreement), which will continue to be in full force and effect.

WAIVER: Except as expressly provided in this Agreement, no amendment or waiver of this Agreement shall be binding unless executed in writing. The waiver by either party of any breach or violation of any provision of this Agreement shall not operate or be construed as a waiver of any subsequent breach or violation.

ENTIRE AGREEMENT: This Agreement constitutes the entire agreement between you and SeaSpine with respect to your employment and supersedes any previous agreements, whether written or oral, express or implied, regarding the same, which are superseded, terminated, and/or cancelled, and you and SeaSpine release and forever discharge the other of and from all manner of actions, causes of action, claims, and demands, under or in respect of, any and all such previous agreements.

MODIFICATION: Any modification of this Agreement must be in writing and signed by both you and SeaSpine or it shall have no effect and shall be void.

GOVERNING LAW: This Agreement shall be governed by and construed in accordance with the laws of the Province of Ontario and federal laws applicable therein.

Please sign (either by hand or electronically) and return a copy of the Agreement (including this letter, the Confidentiality Agreement, and the Dispute Resolution Agreement) to me by May 31, 2021 to confirm your acceptance of these terms. Your signature on this document certifies that you agree with all terms of the Agreement.

I, Beau Standish, confirm that I have read and agree with the terms of this Agreement. I have had a reasonable opportunity to consider this Agreement and the matters set out herein and to obtain independent legal advice if required. By my signature below (whether electronic or handwritten), I voluntarily accept the modified terms of employment with SeaSpine on the terms and conditions set out in this Agreement, including this letter, the Confidentiality Agreement, and the Dispute Resolution Agreement, and SeaSpine’s policies and procedures, including the Employee Handbook, which hereafter constitutes my contract of employment.

I acknowledge that, in this position, I may be considered a “Section 16 reporting person,” which means I am required to report changes in holdings of Company securities to the U.S. Securities and Exchange Commission (“SEC”), am subject to sanctions against “short-swing” trading, and am prohibited from engaging in short sales of Company securities. In addition, the Company may be required to disclose certain personal information about me in its filings with the SEC and its other public disclosures, and I agree and consent to the Company’s disclosure of such information: