AMENDMENT TO LETTER OF INTENT

Additional Conditions. The obligations of the parties contained in clause 4 of the Letter of Intent shall be amended so that the Closing will occur as soon as practicable, but the parties desire the Closing be completed no later than April 9, 2007.

No-Shop. The obligations of the parties contained in clause 5 of the Letter of Intent shall remain in effect until the earliest to occur of (a) the Closing, (b) the date on which Samdrew and Illuminex mutually agree in writing to discontinue negotiations regarding such a transaction on the terms set forth herein, or (c) April 9, 2007.

No Material Changes in Business. The obligations of the parties contained in clause 9 of the Letter of Intent shall remain in effect until the earliest to occur of the termination of the Letter of Intent, April 9, 2007 or the date of execution of the Definitive Agreements.

Binding Nature of Letter. The obligations of the parties contained in clause 10 of the Letter of Intent shall be amended so that the Binding Provisions (along with the rest of the Letter of Intent) may be terminated (A) by mutual written consent of both parties; or (B) upon written notice by either party to the other if the Definitive Agreements have not been executed by April 9, 2007, provided, however, that the termination of the Binding Provisions shall not affect the liability for breach of any of the Binding Provisions prior to the termination.