WORK ORDER NO. 12

Exhibit 10.11

WORK ORDER NO. 12

THIS WORK ORDER NO. 12 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

RADIUS hereby engages Manufacturer to provide Services, as follows:

1.             API/Drug Substance and Product.

BA058

Peptide Sequence:  H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2

2.             Services.  Manufacturer will render to RADIUS the following Services:

Activity 1:

Activity 2:

Activity_3:

Activity_4:

Radius shall place purchase orders with Manufacturer in accordance with Work Order 12 and shall not be permitted to terminate the Services covered by such purchase orders.

3.             Facilities.  The Services described above will be rendered at the Facility unless another facility of Manufacturer is indicated below:

N/A

4.             RADIUS Materials.  RADIUS will provide to Manufacturer the following materials to be used by Manufacturer to perform the Services:

None

5.             RADIUS Equipment.

None

6.             Manufacturer Representative.

Richard W. Coombs,, Sales Manager, Lonza

7.                         RADIUS Representative.

David Hanley, Executive Director, Technical Operations

8.                         Compensation.

Radius will be invoiced 100% upon execution of this Work Order 57’130€.

The total compensation due Manufacturer for Services under this Work Order is not expected to exceed 60’000€

9.                          General: RADIUS and Manufacturer must agree in advance of either party making any change in the compensation due hereunder. Manufacturer will invoice RADIUS to the attention of David Hanley, for Services rendered under this Work Order.  Manufacturer will invoice RADIUS for all amounts due under this Work Order.  All undisputed payments will be made by RADIUS within thirty (30) days of receipt of invoice.

All other terms and conditions of the Agreement will apply to this Work Order.