PTC THERAPEUTICS, INC. Contracts & Agreements

Amended and Restated Exclusive License and Supply Agreement, dated June 2, 2023, by and between PTC Therapeutics, Inc. and Faes Farma, S.A (Filed With SEC on August 8, 2024)

Amendment No. 1 to Amended and Restated Royalty Purchase Agreement and First Put Option Exercise Agreement, dated June 17, 2024, by and among PTC Therapeutics, Inc., Royalty... (Filed With SEC on August 8, 2024)

Employment Agreement between PTC Therapeutics, Inc. and Lee Golden (Filed With SEC on April 25, 2024)

Amended and Restated Royalty Purchase Agreement, dated as of October 18, 2023, among the Registrant, Royalty Pharma Investments 2019 ICAV, and solely for the purposes of Section... (Filed With SEC on February 29, 2024)

Amendment No. 5 to License Agreement dated April 28, 2023 by and between Shiratori Pharmaceutical Co. Ltd. and PTC Therapeutics MP, Inc (Filed With SEC on August 3, 2023)

Employment Agreement between PTC Therapeutics, Inc. and Pierre Gravier (Filed With SEC on July 17, 2023)

Sponsored Research Agreement, as amended dated as of June 1, 2006, by and between the Registrant and Spinal Muscular Atrophy Foundation (Filed With SEC on April 27, 2023)

Funding Agreement, dated as of May 26, 2010, by and between the Registrant and The Wellcome Trust Limited (Filed With SEC on April 27, 2023)

Amended and Restated Employment Agreement between PTC Therapeutics, Inc. and Matthew Klein (Filed With SEC on April 18, 2023)

Consulting Agreement between PTC Therapeutics, Inc. and Stuart W. Peltz (Filed With SEC on March 24, 2023)

Form of Incentive Stock Option Agreement under Amended and Restated 2013 Long Term Incentive Plan (Filed With SEC on February 21, 2023)

Form of Nonstatutory Stock Option Agreement under Amended and Restated 2013 Long Term Incentive Plan (Filed With SEC on February 21, 2023)

Form of Nonstatutory Stock Option Agreement under Amended and Restated 2013 Long Term Incentive PlanNon-employee Director (Filed With SEC on February 21, 2023)

Form of Restricted Stock Unit Agreement under Amended and Restated 2013 Long Term Incentive Plan (Filed With SEC on February 21, 2023)

Amendments to the Funding Agreement, dated as of May 26, 2010, by and between the Registrant and The Wellcome Trust Limited (Filed With SEC on February 21, 2023)

Consulting Services Agreement between the Registrant and Dawn Svoronos (Filed With SEC on December 6, 2022)

Letter Agreement re: Collaboration and License Agreement, dated July 25, 2022, by and between Akcea Therapeutics, Inc. and PTC Therapeutics International Limited (Filed With SEC on October 27, 2022)

Letter Agreement re: Collaboration and License Agreement, dated September 14, 2022, by and between Akcea Therapeutics, Inc. and PTC Therapeutics International Limited (Filed With SEC on October 27, 2022)

Lease Agreement dated May 24, 2022, between Warren CC Acquisitions, LLC and PTC Therapeutics, Inc (Filed With SEC on August 4, 2022)

Irrevocable Transferable Standby Letter of Credit, dated June 22, 2022, issued by HSBC Bank USA, N.A. in favor of Warren CC Acquisitions LLC c/o Vision Real Estate Partners for... (Filed With SEC on August 4, 2022)

PTC Therapeutics, Inc. Amended and Restated 2013 Long-Term Incentive Plan (Filed With SEC on June 9, 2022)

Collaborative Research Agreement Amendment 11, dated as of January 31, 2022 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on May 3, 2022)

Commercial Manufacturing Agreement, dated as of September 18, 2015, as amended, by and between Alcami Corporation (f/k/a/ AAI Pharma Services Corp.) and Complete Pharma Holdings,... (Filed With SEC on May 3, 2022)

Description of Registered Securities (Filed With SEC on February 22, 2022)

Employment Agreement, as amended, between the Registrant and Matthew Klein (Filed With SEC on February 22, 2022)

Collaborative Research Agreement Amendment 10, dated as of November 1, 2021 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on February 22, 2022)

PTC Therapeutics, Inc. Amended and Restated 2016 Employee Stock Purchase Plan (Filed With SEC on June 9, 2021)

Collaborative Research Agreement Amendment 9, dated as of March 21, 2021 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on May 4, 2021)

Collaborative Research Agreement Amendment 7, dated as of September 14, 2020 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on February 25, 2021)

Collaborative Research Agreement Amendment 8, dated as of December 5, 2020 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on February 25, 2021)

Collaborative Research Agreement Amendment 5, dated as of January 17, 2020 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on October 29, 2020)

Collaborative Research Agreement Amendment 6, dated as of May 30, 2020 by and between National Taiwan University and PTC Therapeutics GT, Inc (Filed With SEC on October 29, 2020)

License Agreement dated as of February 8, 2016, as amended, by and between Shiratori Pharmaceutical Co. Ltd. and Censa Pharmaceuticals Inc (Filed With SEC on August 5, 2020)

Royalty Purchase Agreement, dated as of July 17, 2020, by and among PTC Therapeutics, Inc., RPI 2019 Intermediate Finance Trust, and, solely for the limited purposes set forth... (Filed With SEC on August 5, 2020)

Employment Agreement, as amended, between the Registrant and Matthew Klein (Filed With SEC on August 5, 2020)

Employment Agreement, as amended, between the Registrant and Eric Pauwels (Filed With SEC on August 5, 2020)

Agreement and Plan of Merger, dated May 5, 2020, by and among PTC Therapeutics, Inc., Hydro Merger Sub, Inc., Censa Pharmaceuticals Inc. and, solely in its capacity as... (Filed With SEC on May 6, 2020)

Second Amendment to Lease Agreement dated as of March 25, 2020 by and between Bristol-Myers Squibb Company and PTC Therapeutics, Inc (Filed With SEC on April 30, 2020)

Rights Exchange Agreement, by and among PTC Therapeutics, Inc., the Rightholders set forth therein, and, for the limited purposes set forth therein, Shareholder Representative... (Filed With SEC on April 30, 2020)

Description of Registered Securities (Filed With SEC on March 2, 2020)

License and Technology Transfer Agreement Amendment No. 2, dated December 1, 2019, by and among National Taiwan University, Professor Wu-Lian (Paul) Hwu and PTC Therapeutics GT,... (Filed With SEC on March 2, 2020)

First Amendment to Lease Agreement dated as of October 7, 2019 by and between Bristol-Myers Squibb Company and PTC Therapeutics, Inc (Filed With SEC on March 2, 2020)

Amendment No. 2 to Credit and Security Agreement, dated as of August 7, 2019, by and among PTC Therapeutics, Inc., MidCap Financial Trust and the Lenders as defined therein (Filed With SEC on October 30, 2019)

Amendment No. 3 to Credit and Security Agreement, dated as of August 29, 2019, by and among PTC Therapeutics, Inc., MidCap Financial Trust and the Lenders as defined therein (Filed With SEC on October 30, 2019)

Amendment No. 4 to Credit and Security Agreement, dated as of September 17, 2019, by and among PTC Therapeutics, Inc., MidCap Financial Trust and the Lenders as defined therein (Filed With SEC on October 30, 2019)

Omnibus Amendment No. 5 and Joinder to Credit and Security Agreement and Amendment and Joinder to Pledge Agreement, dated as of October 1, 2019, by and among PTC Therapeutics,... (Filed With SEC on October 30, 2019)

Irrevocable Standby Letter of Credit, dated September 3, 2019, issued by HSBC Bank USA, N.A. in favor of Bristol-Myers Squibb Company for the Account of PTC Therapeutics, Inc., as... (Filed With SEC on October 30, 2019)

Lease Agreement dated as of August 3, 2019, by and between Bristol-Myers Squibb Company and PTC Therapeutics, Inc (Filed With SEC on October 30, 2019)

Asset Purchase Agreement by and between PTC Therapeutics, Inc. and BioElectron, dated October 1, 2019 (Filed With SEC on October 30, 2019)

Underwriting Agreement, dated as of September 18, 2019, by and between PTC Therapeutics Inc. and Credit Suisse Securities (USA) LLC, as the Underwriter (Filed With SEC on September 20, 2019)

Indenture (including Form of Note), dated as of September 20, 2019, by and between PTC Therapeutics, Inc. and U.S. Bank National Association, a national banking association, as... (Filed With SEC on September 20, 2019)

At the Market Offering Sales Agreement, dated August 7, 2019, among PTC Therapeutics, Inc., Cantor Fitzgerald & Co. and RBC Capital Markets, LLC (Filed With SEC on August 7, 2019)

Employment Agreement, as amended, between the Registrant and Emily Hill (Filed With SEC on August 6, 2019)

Employment Agreement, as amended, between the Registrant and Christine Utter (Filed With SEC on August 6, 2019)

Underwriting Agreement, dated January 22, 2019, by and between PTC Therapeutics, Inc. and RBC Capital Markets, LLC, as the Underwriter (Filed With SEC on January 25, 2019)

Collaborative Research Agreement, dated September 30, 2015, as amended, by and between National Taiwan University and Agilis Biotherapeutics, Inc. (formerly Agilis... (Filed With SEC on November 5, 2018)

License and Technolgy Transfer Agreement, dated December 23, 2015, by and between National Taiwan University and Agilis Biotherapeutics, Inc. (formerly Agilis Biotherapeutics, LLC) (Filed With SEC on November 5, 2018)

Collaboration and License Agreement, dated August 1, 2018, by and between PTC Therapeutics International Limited and Akcea Therapeutics, Inc (Filed With SEC on November 5, 2018)

Underwriting Agreement, dated March 28, 2018, by and among PTC Therapeutics, Inc. and Credit Suisse Securities (USA) LLC and Citigroup Global Markets Inc., as representatives of... (Filed With SEC on April 3, 2018)

Consulting Services Agreement between the Registrant and Dr. C. Geoffrey McDonough (Filed With SEC on September 18, 2017)

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. EXCLUSIVE LICENSE AND SUPPLY AGREEMENT (Filed With SEC on August 9, 2017)

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. COMMERCIAL MANUFACTURING AGREEMENT (Filed With SEC on August 9, 2017)

EMPLOYMENT AGREEMENT (Filed With SEC on August 9, 2017)

PTC CONSULTING SERVICES AGREEMENT (Filed With SEC on August 8, 2017)

CREDIT AND SECURITY AGREEMENT dated as of May 5, 2017 by and among PTC THERAPEUTICS, INC., and any additional borrower that hereafter becomes party hereto, each as Borrower, and... (Filed With SEC on May 8, 2017)

PLEDGE AGREEMENT (Filed With SEC on May 8, 2017)

INTELLECTUAL PROPERTY SECURITY AGREEMENT (Filed With SEC on May 8, 2017)

PTC THERAPEUTICS, INC. RESTRICTED STOCK AWARD AGREEMENT (Filed With SEC on March 16, 2017)

ASSET PURCHASE AGREEMENT by and between PTC Therapeutics, Inc., as Buyer and Marathon Pharmaceuticals, LLC, as Seller Dated as of March 15, 2017 TABLE OF CONTENTS (Filed With SEC on March 16, 2017)

PTC SERVICES AGREEMENT (Filed With SEC on April 27, 2016)

PTC Therapeutics, Inc. Nonstatutory Stock Option Agreement Granted Under 2013 Long-Term Incentive Plan (Filed With SEC on February 29, 2016)

PTC THERAPEUTICS, INC. RESTRICTED STOCK UNIT AGREEMENT (Filed With SEC on February 29, 2016)

PTC THERAPEUTICS, INC. AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of August 14, 2015 3.00% Convertible Senior Notes due 2022 (Filed With SEC on August 14, 2015)

PTC Therapeutics, Inc. Inducement Grant Nonstatutory Stock Option Agreement (Filed With SEC on March 2, 2015)

PTC Therapeutics, Inc. Incentive Stock Option Agreement Granted Under 2013 Long-Term Incentive Plan (Filed With SEC on March 2, 2015)

PTC Therapeutics, Inc. Nonstatutory Stock Option Agreement Granted Under 2013 Long-Term Incentive Plan (Filed With SEC on March 2, 2015)

SEPARATION AND GENERAL RELEASE AGREEMENT (Filed With SEC on March 2, 2015)

PTC THERAPEUTICS, INC. 3,000,000 Shares of Common Stock Underwriting Agreement (Filed With SEC on October 10, 2014)

EMPLOYMENT AGREEMENT (Filed With SEC on May 6, 2014)

PTC THERAPEUTICS, INC. Shares of Common Stock Underwriting Agreement (Filed With SEC on February 10, 2014)

PTC THERAPEUTICS, INC. Shares of Common Stock Underwriting Agreement (Filed With SEC on June 5, 2013)

EMPLOYMENT AGREEMENT (Filed With SEC on June 5, 2013)

PTC Therapeutics, Inc. NOTICE OF AWARD FOR INCENTIVE STOCK OPTION (Filed With SEC on May 28, 2013)

PTC Therapeutics, Inc. NOTICE OF AWARD FOR NONSTATUTORY STOCK OPTION (Filed With SEC on May 28, 2013)

PTC Therapeutics, Inc. 2013 Long-Term Incentive Plan (Filed With SEC on May 28, 2013)

PTC Therapeutics, Inc. Incentive Stock Option Agreement Granted Under 2013 Long-Term Incentive Plan (Filed With SEC on May 28, 2013)

PTC Therapeutics, Inc. Nonstatutory Stock Option Agreement Granted Under 2013 Long-Term Incentive Plan (Filed With SEC on May 28, 2013)

AMENDED AND RESTATED EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2013)

EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2013)

AMENDED AND RESTATED EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2013)

EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2013)

PTC THERAPEUTICS, INC. SECOND AMENDED AND RESTATED INVESTORS RIGHTS AGREEMENT Dated as of March 7, 2013 (Filed With SEC on May 16, 2013)

PTC THERAPEUTICS, INC. EIGHTH AMENDED AND RESTATED 1998 EMPLOYEE, DIRECTOR AND CONSULTANT STOCK OPTION PLAN (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. INCENTIVE STOCK OPTION CERTIFICATE (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. NON-QUALIFIED STOCK OPTION CERTIFICATE (Filed With SEC on May 16, 2013)

PTC THERAPEUTICS, INC. 2009 EQUITY AND LONG TERM INCENTIVE PLAN (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. NOTICE OF AWARD FOR INCENTIVE STOCK OPTION (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. NOTICE OF AWARD FOR NONSTATUTORY STOCK OPTION (Filed With SEC on May 16, 2013)

PTC THERAPEUTICS, INC. 2013 STOCK INCENTIVE PLAN (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. Restricted Stock Agreement Granted Under 2013 Stock Incentive Plan (Filed With SEC on May 16, 2013)

PTC Therapeutics, Inc. Nonstatutory Stock Option Agreement Granted Under 2013 Stock Incentive Plan (Filed With SEC on May 16, 2013)

EX-4.2: FIFTH AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (Filed With SEC on March 31, 2006)

EX-4.3: WARRANT (Filed With SEC on March 31, 2006)

EX-4.4: WARRANT (Filed With SEC on March 31, 2006)

EX-4.5: WARRANT (Filed With SEC on March 31, 2006)

EX-4.6: WARRANT (Filed With SEC on March 31, 2006)

EX-4.7: WARRANT (Filed With SEC on March 31, 2006)

EX-4.8: WARRANT (Filed With SEC on March 31, 2006)

EX-4.9: WARRANT (Filed With SEC on March 31, 2006)

EX-4.10: WARRANT (Filed With SEC on March 31, 2006)

EX-10.1: SIXTH AMENDED AND RESTATED 1998 STOCK OPTION PLAN (Filed With SEC on March 31, 2006)

EX-10.4: RESEARCH COLLABORATION AND EXCLUSIVE OPTION AGREEMENT (Filed With SEC on March 31, 2006)

EX-10.5: COLLABORATION AND LICENSE AGREEMENT (Filed With SEC on March 31, 2006)

EX-10.12: LEASE AGREEMENT (Filed With SEC on March 31, 2006)

EX-10.13: MASTER SECURITY AGREEMENT (Filed With SEC on March 31, 2006)

EX-10.14: FORM OF PROMISSORY NOTE (Filed With SEC on March 31, 2006)

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PTC THERAPEUTICS, INC. Contracts & Agreements