PORTOLA PHARMACEUTICALS INC Contracts & Agreements

Amended and Restated Portola Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (Filed With SEC on May 11, 2020)

Offer Letter by and between Portola Pharmaceuticals, Inc. and Rajiv Patni dated December 19, 2019 (Filed With SEC on May 11, 2020)

Agreement and Plan of Merger, dated as of May 5, 2020, by and among Portola Pharmaceuticals, Inc., Alexion Pharmaceuticals, Inc. and Odyssey Merger Sub Inc (Filed With SEC on May 7, 2020)

Description of securities of Portola Pharmaceuticals, Inc. registered under Section 12 of the Exchange Act (Filed With SEC on February 28, 2020)

Amendment No. 1 to Credit Agreement, dated August 15, 2019, to the Credit Agreement, dated February 28, 2019 (Filed With SEC on November 5, 2019)

Underwriting Agreement, dated August 13, 2019 (Filed With SEC on August 14, 2019)

Amended and Restated Portola Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (Filed With SEC on August 7, 2019)

Sixth Amendment To Lease dated June 28, 2019 (Filed With SEC on August 7, 2019)

Portola Pharmaceuticals, Inc. 2013 Equity Incentive Plan and Amendment dated February 27, 2019 (Filed With SEC on May 8, 2019)

Portola Pharmaceuticals, Inc. Amended and Restated Inducement Plan and Amendment dated February 27, 2019 (Filed With SEC on May 8, 2019)

Offer Letter by and between Portola Pharmaceuticals, Inc. and Ernie Meyer dated June 26, 2018 (Filed With SEC on May 8, 2019)

Offer Letter by and between Portola Pharmaceuticals, Inc. and Sheldon Koenig dated January 17, 2019 (Filed With SEC on May 8, 2019)

Consulting Agreement between Portola Pharmaceuticals, Inc. and Charles Homcy, M.D. dated as of March 28, 2019 (Filed With SEC on May 8, 2019)

Manufacturing Services Agreement by and between Lonza AG and Portola Pharmaceuticals, Inc., effective as of August 15, 2017 (Filed With SEC on May 8, 2019)

Amended and Restated Pharmaceuticals, Inc. Inducement Plan (Filed With SEC on March 1, 2019)

Credit Agreement by and between Portola Pharmaceuticals, Inc. (the Borrower), certain domestic subsidiaries of the Borrower (the Guarantors), HCR Collateral Management, LLC (the... (Filed With SEC on March 1, 2019)

Letter Agreement by and between Portola Pharmaceuticals, Inc. and Tao Fu, dated August 31, 2018 (Filed With SEC on November 7, 2018)

Form of Executive Severance Benefits Agreement (amends and restates the form of Executive Severance Benefits Agreement filed by the Company on August 6, 2014) (Filed With SEC on October 12, 2018)

Offer Letter between Portola Pharmaceuticals, Inc. and Scott Garland, dated September 10, 2018 (Filed With SEC on September 20, 2018)

Letter Agreement with John T. Curnutte, M.D., Ph.D dated June 3, 2018 (Filed With SEC on August 9, 2018)

Letter Agreement with Mardi C. Dier dated June 3, 2018 (Filed With SEC on August 9, 2018)

Letter Agreement with John H. Lawrence, M.D. dated June 3, 2018 (Filed With SEC on August 9, 2018)

Letter Agreement with John B. Moriarty, J.D. dated June 3, 2018 (Filed With SEC on August 9, 2018)

Offer Letter by and between Portola Pharmaceuticals, Inc. and John H. Lawrence, M.D. dated October 18, 2017 (Filed With SEC on August 9, 2018)

Offer Letter by and between Portola Pharmaceuticals, Inc. and John B. Moriarty dated January 18, 2018 (Filed With SEC on August 9, 2018)

Offer Letter by and between Portola Pharmaceuticals, Inc. and Glenn Brame dated June 8, 2018 (Filed With SEC on August 9, 2018)

Letter agreement with Bill Lis dated June 3, 2018 (Filed With SEC on June 4, 2018)

Amended and Restated Non-Employee Director Compensation Policy (Filed With SEC on May 10, 2018)

Portola Pharmaceuticals, Inc. 2013 Employee Stock Purchase Plan (Filed With SEC on November 9, 2017)

Portola Pharmaceuticals, Inc. Inducement Plan (Filed With SEC on November 9, 2017)

Form of Stock Option Grant Notice - Inducement Plan (Filed With SEC on November 9, 2017)

Form of Stock Option Grant Notice for Officers - Inducement Plan (Filed With SEC on November 9, 2017)

Form of Option Agreement - Inducement Plan (Filed With SEC on November 9, 2017)

Form of Restricted Stock Unit Award Grant Notice - Inducement Plan (Filed With SEC on November 9, 2017)

Form of Restricted Stock Unit Award Grant Notice for Officers - Inducement Plan (Filed With SEC on November 9, 2017)

Form of Award Agreement Inducement Plan (Filed With SEC on November 9, 2017)

Underwriting Agreement, dated September 12, 2017 (Filed With SEC on September 13, 2017)

Purchase and Sale Agreement dated as of February 2, 2017 between Portola Pharmaceuticals, Inc., and certain entities managed by Healthcare Royalty Management, LLC (Filed With SEC on May 9, 2017)

2016 SUPPLEMENTAL FUNDING SUPPORT LOAN AGREEMENT (Filed With SEC on March 1, 2017)

Amended and Restated COMMERCIAL SUPPLY (MANUFACTURING SERVICES) AGREEMENT BETWEEN CMC ICOS Biologics, Inc. and Portola Pharmaceuticals, Inc. (Filed With SEC on March 1, 2017)

Portola Pharmaceuticals, Inc. Stock Option Grant Notice 2013 Equity Incentive Plan (Filed With SEC on August 9, 2016)

Portola Pharmaceuticals, Inc. Restricted Stock Unit Award Grant Notice 2013 Equity Incentive Plan (Filed With SEC on August 9, 2016)

PORTOLA PHARMACEUTICALS, INC. PERFORMANCE STOCK UNIT AWARD GRANT NOTICE 2013 EQUITY INCENTIVE PLAN (Filed With SEC on August 9, 2016)

AMENDED AND RESTATED PORTOLA PHARMACEUTICALS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY (Filed With SEC on May 6, 2016)

AMENDED AND RESTATED PORTOLA PHARMACEUTICALS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY (Filed With SEC on February 29, 2016)

Portola Pharmaceuticals, Inc. Performance Stock Unit Award Grant Notice 2013 Equity Incentive Plan (Filed With SEC on February 29, 2016)

3,125,000 Shares Portola Pharmaceuticals, Inc. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT December 3, 2015 (Filed With SEC on December 4, 2015)

AMENDED AND RESTATED PORTOLA PHARMACEUTICALS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY (Filed With SEC on November 9, 2015)

-SIGNATURE ON NEXT PAGE- (Filed With SEC on August 5, 2015)

2,495,652 Shares Portola Pharmaceuticals, Inc. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT March 10, 2015 (Filed With SEC on March 11, 2015)

Portola Pharmaceuticals, Inc. Restricted Stock Unit Grant Notice 2013 Equity Incentive Plan (Filed With SEC on March 2, 2015)

Portola Pharmaceuticals, Inc. Performance Stock Unit Award Grant Notice 2013 Equity Incentive Plan (Filed With SEC on March 2, 2015)

COMMERCIAL SUPPLY (MANUFACTURING SERVICES) AGREEMENT BETWEEN CMC ICOS Biologics, Inc. and Portola Pharmaceuticals, Inc. (Filed With SEC on November 10, 2014)

6,200,000 Shares Portola Pharmaceuticals, Inc. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT October 2, 2014 (Filed With SEC on October 3, 2014)

EXECUTIVE SEVERANCE BENEFITS AGREEMENT (Filed With SEC on July 2, 2014)

[] Shares Portola Pharmaceuticals, Inc. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT [], 2013 (Filed With SEC on October 16, 2013)

Additional abbreviationsmay also be used though not in the above list. (Filed With SEC on May 17, 2013)

Shares Portola Pharmaceuticals, Inc. COMMON STOCK, PAR VALUE $0.001 PER SHARE UNDERWRITING AGREEMENT , 2013 (Filed With SEC on May 7, 2013)

PORTOLA PHARMACEUTICALS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY (Filed With SEC on May 7, 2013)

License and Collaboration Agreement by and between Portola Pharmaceuticals, Inc. and Biogen Idec MA Inc. Table of Contents (continued) (Filed With SEC on May 7, 2013)

PORTOLA PHARMACEUTICALS, INC. INDEMNITY AGREEMENT (Filed With SEC on April 12, 2013)

PORTOLA PHARMACEUTICALS, INC. 2013 EQUITY INCENTIVE PLAN ADOPTED BY THE BOARD OF DIRECTORS:JANUARY 30, 2013 AMENDED BY THE BOARDOF DIRECTORS: FEBRUARY 27, 2013 APPROVED BYTHE... (Filed With SEC on April 12, 2013)

2006 EXECUTIVE CHANGE IN CONTROL SEVERANCE BENEFITS AGREEMENT (Filed With SEC on April 12, 2013)

PORTOLA PHARMACEUTICALS, INC. THIRD AMENDED AND RESTATED INVESTORRIGHTS AGREEMENT November 18, 2011 TABLE OF CONTENTS (Filed With SEC on April 12, 2013)

License and Collaboration Agreement by and between Portola Pharmaceuticals, Inc. and Biogen Idec MA Inc. Table of Contents (continued) (Filed With SEC on April 12, 2013)

TABLE OF CONTENTS (Filed With SEC on April 12, 2013)

ASSET PURCHASE AGREEMENT between: MILLENNIUM PHARMACEUTICALS,INC., a Delaware corporation; and PORTOLA PHARMACEUTICALS,INC., a Delaware corporation Dated as of November 7, 2003... (Filed With SEC on April 12, 2013)

SECOND AMENDED AND RESTATED LICENSE AGREEMENT (Filed With SEC on April 12, 2013)

Clinical Collaboration Agreement by and among Portola Pharmaceuticals, Inc., Bristol-Myers Squibb Company, and Pfizer Inc. CLINICAL COLLABORATION AGREEMENT (Filed With SEC on April 12, 2013)

LEASE (Filed With SEC on April 12, 2013)

FIRST AMENDMENT TO LEASE (Filed With SEC on April 12, 2013)

Portola Pharmaceuticals, Inc. 270 E. Grand Avenue, Ste. 22 South San Francisco, CA 04080 ###-###-#### (Filed With SEC on April 12, 2013)

PORTOLA PHARMACEUTICALS, INC. 2013 EMPLOYEE STOCK PURCHASE PLAN ADOPTED BY THE BOARD OF DIRECTORS:JANUARY 30, 2013 APPROVED BY THESTOCKHOLDERS: MARCH 8, 2013 (Filed With SEC on April 12, 2013)

MASTER CONTRACT SERVICES AGREEMENT FOR PRECLINICAL AND CLINICAL SERVICES (Filed With SEC on April 12, 2013)

DEVELOPMENT AND MANUFACTURING SERVICES AGREEMENT (Filed With SEC on April 12, 2013)

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PORTOLA PHARMACEUTICALS INC Contracts & Agreements