CONFIDENTIAL TREATMENT REQUESTED

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT

1. CONTRACT ID CODE

PAGE OF PAGES

N/A

2. AMENDMENT/MODIFICATION NO.

0006

3. EFFECTIVE DATE

[See block 16C, below]

4. REQUISITION/PURCHASE REQ. NO.

5 PROJECT NO, (If applicable)

N/A

6. ISSUED BY

7. ADMINISTERED BY (If other than Item 6)

National Institutes of Health

National Institute of Allergy and Infectious Diseases

DEA, Office of Acquisitions

Room 3214, Msc 7612

6700-B Rockledge Drive

Bethesda, MD 20892-7612

        MID RCB-B

8. NAME AND ADDRESS OF CONTRACTOR (No., Street, County, State and ZIP Code)

9A. AMENDMENT OF SOLICITATION NO.

Pfenex, Inc

10790 Roselle Street

San Diego, Ca 92121

9B. DATED (SEE ITEM 11)

  X  

10A. MODIFICATION OF CONTRACT/ORDER NO.

  HHSN272201200033C

10B. DATED (SEE ITEM 13)

09/27/2012

CODE

FACILITY CODE

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

¨ The above numbered solicitation is amended as set forth in Item 14. The hour end date specified for receipt of Offers        ¨ is extended,             ¨ is not extended Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing Items 8 and 15, and returning one (1) copy of the amendment; (b) By acknowledging receipt of this Amendment on each copy of the offer submitted; or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGEMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

12. ACCOUNTING AND APPROPRIATION DATA (if required)

13. THIS ITEM ONLY APPLIES TO MODIFICATION OF CONTRACTS/ORDERS.

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

  (¨)  

THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation data, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF

THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

Mutual Agreement of the Parties

D.

E.  IMPORTANT:    Contractor        ¨ is not,        x is required to sign this document and return 2 copies to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

PURPOSE:  The purpose of the modification is to revise ARTICLE G.2.

TOTAL FUNDS CURRENTLY ALLOTTED : $3,031,414 (Unchanged)

TOTAL ESTIMATED COST: $3,031,414 (Unchanged)

FUNDED THROUGH DATE: March 31, 2016 (Unchanged)

COMPLETION DATE: March 31, 2016 (Uncharged)

15A. NAME AND TITLE OF SIGNER (Type or print)

16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

HUBERT CHEN - CHIEF MEDICAL OFFICER

Michael P. Welsh

Contracting Officer, MID RCB-B, OA, DEA, NIAID, NIH, DHHS

15B. CONTRACTOR/OFFEROR

15C. DATE SIGNED  

16C. DATE SIGNED

/s/ Hubert Chen                                       

Oct 30, 2015

By: /s/ Michael P. Welsh               

Nov 2, 2015

(Signature of person authorized to sign)

Contract No: HHSN272201200033C

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Principal Investigator

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Deputy Principle Investigator

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Clinician focused on pre-clinical and clinical studies

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Director Downstream Processing (DSP) and Analytical Biochemistry

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Project Manager

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Project Control Manager