CONFIDENTIAL TREATMENT REQUESTED

            AMENDMENT OF  SOLICITATION/MODIFICATION OF CONTRACT

1. CONTRACT ID CODE            

    PAGE OF PAGES            

    2. AMENDMENT/MODIFICATION NO.    

            0008

    3. EFFECTIVE DATE                     

    See Block 16C

    6.ISSUED BY                         

National Institutes of Health

National Institute of Allergy and Infectious Diseases

DEA, Office of Acquisitions

Room 3B49, MSC 9821

5601 Fishers Lane

Bethesda, MD 20892-9821

MID RCB-B

    9A. AMENDMENT OF SOLICITATION NO.

Pfenex, Inc.

10790 Roselle Street

San Diego, CA 92121

    9B. DATED (SEE ITEM 11)

    10A. MODIFICATION OF CONTRACT/ORDER NO.

              HHSN272201200033C

    10B. DATED (SEE ITEM 13)

        09/27/2012

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

¨ The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers                 ¨ is extended,                 ¨ is not extended.

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing Items 8 and 15, and returning one (1) copy of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATA SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and data specified.

    12. ACCOUNTING AND APPROPRIATION DATA (If required)

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14. 

    (¨)   

A.    THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

B.    THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation date, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF

    X   

C.    THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

Mutual Agreement of the Parties

D.    OTHER (Specify type of modification and authority)

    E. IMPORTANT:      Contractor        ¨ is not,        x is required to sign this document and return     1     copies to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

PURPOSE: The purpose of this modification is to extend the period of performance for Option 1; exercise quantity Option 2; provide associated funding in

    the amount of $[***]; reduce the contract ceiling; revise the SOW; and update various articles.

Total Funds Currently Obligated

Total Estimated Amount of Contract

Prior to this Mod

This Mod 8

Revised Total

    15A. NAME AND TITLE OF SIGNER (Type or print)

    Patrick Lucy, Chief Business Officer

16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

    Michael P. Welsh

Contracting Officer, MID RCB-B, OA, DEA, NIAID, NIH, DHHS

    15B. CONTRACTOR/OFFEROR

    /s/ Patrick Lucy                                             

    (Signature of person authorized to sign)

15C. DATE SIGNED

May 13, 2016

16B_: UNITED STATES OF AMERICA

By: /s/ Michael P. Welsh                                 

              (Signature of Contracting Officer)

16C. DATE SIGNED

May 16, 2016

NSN 7540-01-152-8070

PREVIOUS EDITION UNUSABLE

30-105

Computer Generated

STANDARD FORM 30 (REV. 10-83)

Prescribed by GSA

FAR (48 CFR) 53,243

Contract No: HHSN272201200033C

The estimated cost of this contract is $[***].

The fixed fee of this contract is $[***]. The fixed fee shall be subject to the withholding provisions of the clauses ALLOWABLE COST AND PAYMENT and FIXED FEE referenced in the General Clauses Listing in Part II, ARTICLE I.1. of this contract.

The total estimated amount of the contract, represented by the sum of the estimated cost plus the fixed fee for the Base Period and Option 1 is $[***].

If the Government exercises its option pursuant to the OPTION PROVISIONS Article in SECTION H of this contract, the Government’s total estimated contract amount represented by the sum of the estimated cost plus the fixed fee will be increased as follows:

Estimated Cost      

Plus Fixed Fee      

Base Period (exercised)

Option 1 (exercised)

Option 2 (exercised)

Option 3

Option 4

Option 5

Option 6

Option 7

Option 8

Option 9

Option 10

Option 11

Option 12

Option 13

Total

Payments shall be made from the PRISM / NBS Line Item Numbers as follows:

Line 1

Line 2

Line 3

Contract No: HHSN272201200033C

Fee Payment Schedule Based on Contract Milestones:

Upon Completion of

the task as described in       

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the task as described in

the SOW

Upon Completion of

the tasks as described in

the SOW

Upon Completion of

the tasks as described in the SOW

Upon Completion of

the tasks as described in the SOW

Upon Completion of

the tasks as described in

the SOW

Contract No: HHSN272201200033C

Upon Completion of

the tasks as described

in the SOW

Option 2 Total

Contract No: HHSN272201200033C

[***]                     

[***]

[***]

[***]

[***]

[***]