Amendment No. 1 to Second Amended and Restated Registration Rights Agreement by and among Perlegen Sciences, Inc., Pfizer Overseas Pharmaceuticals, and Prior Purchasers
This amendment, effective December 22, 2005, updates the existing Registration Rights Agreement between Perlegen Sciences, Inc. and its preferred stockholders to add Pfizer Overseas Pharmaceuticals as a party. It extends registration rights to shares of Series D-1 Preferred Stock and their convertible common stock, ensuring these securities are covered under the agreement. The amendment also updates definitions and contact information, while keeping all other terms of the original agreement in effect. The parties involved include Perlegen Sciences, Pfizer, and several investment funds.
2900 Cork Airport Business Park
Airport Road
Cork, Ireland
Attn: Legal Director
235 East 42nd Street
New York, NY 10017
Attn: General Counsel
50 Pequot Avenue
New London, CT 06320
Attn: General Counsel
PERLEGEN SCIENCES, INC. | ||||||
By: | /s/ Brad A. Margus | |||||
Name: | ||||||
Title: | President and Chief Executive Officer | |||||
Address: | ||||||
Perlegen Sciences, Inc. | ||||||
2021 Stierlin Court | ||||||
Mountain View, California 94043 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
MAVERICK FUND LDC | |||||||
By: | /s/ John McCafferty | ||||||
Name: | |||||||
Title: | |||||||
Address: | |||||||
Maverick Capital | |||||||
300 Crescent Court, 18th Floor | |||||||
Dallas, TX 75201 | |||||||
Attn: | John McCafferty, General Counsel |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
MAVERICK FUND USA, LTD. | ||||||
By: | /s/ John McCafferty | |||||
Name: | ||||||
Title: | ||||||
Address: Maverick Capital | ||||||
300 Crescent Court, 18th Floor | ||||||
Dallas, TX 75201 | ||||||
Attn: | John McCafferty, General Counsel |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
MAVERICK FUND II, LTD. | ||||||
By: | /s/ John McCafferty | |||||
Name: | ||||||
Title: | ||||||
Address Maverick Capital | ||||||
300 Crescent Court, 18th Floor | ||||||
Dallas, TX 75201 | ||||||
Attn: | John McCafferty, General Counsel |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
VULCAN VENTURES INC. | ||||||
By: | /s/ W. Lance Conn | |||||
Name: | W. Lance Conn | |||||
Title: | Executive Vice President | |||||
Address: | ||||||
Michael Kranda | ||||||
505 5th Avenue South, Suite 900 | ||||||
Seattle, WA 98104 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
UNILEVER TECHNOLOGY VENTURES FUND B.V. | ||||||
By: | /s/ Loek Helderman | |||||
Name: | Loek Helderman | |||||
Title: | | |||||
By: | /s/ W. G. M. Mulders | |||||
Name: | W. G. M. Mulders | |||||
Title: | Director | |||||
Address: | ||||||
455 Weena | ||||||
3013 AL Rotterdam The Netherlands |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
BIOMEDICAL SCIENCES INVESTMENT FUND PTE LTD | ||||||
By: | /s/ Chu Swee Yeok | |||||
Name: | Chu Swee Yeok | |||||
Title: | Director | |||||
Address: | ||||||
20 Biopolis Way | ||||||
#09-01 Centros | ||||||
Singapore 138668 | ||||||
Attention: Sim Sze Kuan |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
SB LIFE SCIENCE VENTURES I, L.P. Mr. Kazuhiko Kasai, Director SB Life Science Pte. Ltd. as general partner of SB Life Science Partners, L.P. as general partner of SB Life Ventures I, L.P. | ||||||
By: | /s/ Kazuhiko Kasai | |||||
Name: | Kazuhiko Kasai | |||||
Title: | Director | |||||
Address: | ||||||
24F, Tokyo Shiodone Building | ||||||
1-9-1 Higashi-shimbashi Minato-ku Tokyo, 105-7303 Japan | ||||||
Attention: Mayo Hotta |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CMEA VENTURES LIFE SCIENCES 2000, L.P. | ||||||
By: | /s/ Tom Baruch | |||||
Name: | Tom Baruch | |||||
Title: | General Partner | |||||
Address: | ||||||
CMEA Ventures Life Sciences 2000 Limited | ||||||
Partnership | ||||||
One Embarcadero Center, Suite 3250 | ||||||
San Francisco, CA 94111-3600 | ||||||
Attn: | Tom Baruch |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CMEA VENTURES LIFE SCIENCES 2000, CIVIL LAW PARTNERSHIP | ||||||
By: | /s/ Tom Baruch | |||||
Name: | Tom Baruch | |||||
Title: | General Partner | |||||
Address: | ||||||
CMEA Ventures Life Sciences 2000 Civil Law | ||||||
Partnership | ||||||
One Embarcadero Center, Suite 3250 | ||||||
San Francisco, CA 94111-3600 | ||||||
Attn: | Tom Baruch |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
BSI SA. | ||||||
By: | /s/ Thomas Streule | |||||
Name: | Thomas Streule | |||||
Title: | Assistant Vice President | |||||
By: | /s/ Patrizia Solari | |||||
Name: | Patrizia Solari | |||||
Title: | Vice President | |||||
Address: | ||||||
BSI SA | ||||||
Thomas Streule | ||||||
Assistant Vice President | ||||||
Securities Administration | ||||||
Via Magatti 2 | ||||||
6901 Lugano | ||||||
Switzerland |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
BSI NEW BIOMEDICAL FRONTIER (SICAV) | ||||||
By: | /s/ Raoul Paglia | |||||
Name: | Raoul Paglia | |||||
Title: | Manager | |||||
Address: | BSI-New BioMedical Frontier | |||||
(SICAV) | ||||||
Via Peri 23 | ||||||
6900 Lugano | ||||||
Switzerland | ||||||
Attn: Francesco Badaracco |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ZAFFARONI REVOCABLE TRUST 1/24/86 | ||||||
By: | /s/ Alejandro Zaffaroni | |||||
Name: | Alejandro Zaffaroni | |||||
Title: | Trustee | |||||
Address: | ||||||
Gonzalo M. Silveira | ||||||
c/o Technofyn Associates, LLC | ||||||
4005 Miranda Avenue, Suite 180 | ||||||
Palo Alto, CA ###-###-#### |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CSK VENTURE CAPITAL CO., LTD. as Investment Manager for Hitachi CSK Internet Business Fund | ||||||
By: | /s/ Shunichi Ishimura | |||||
Name: | Shunichi Ishimura | |||||
Title: | President | |||||
Address: | ||||||
5th Floor, Reviera Minami Aoyama Bldg. | ||||||
3-3-3 Minai-Aoyama, Minato-ku | ||||||
Tokyo 107-0062 | ||||||
Japan | ||||||
Attn: Makoto Kaneshiro |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CSK VENTURE CAPITAL CO., LTD. as Investment Manager CSK-4 Investment Fund | ||||||
By: | /s/ Shunichi Ishimura | |||||
Name: | Shunichi Ishimura | |||||
Title: | President | |||||
Address: | ||||||
5th Floor, Reviera Minami Aoyama Bldg. | ||||||
3-3-3 Minai-Aoyama, Minato-ku | ||||||
Tokyo 107-0062 | ||||||
Japan | ||||||
Attn: | Makoto Kaneshiro |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Laura L. De Surraco | ||
LAURA L. DE SURRACO | ||
Address: | ||
1732 West Selby Lane | ||
Redwood City, CA 94061 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
THE 1989 LEECH LIVING TRUST | ||||
By: | /s/ Ana M. Leech | |||
Name: | Ana M. Leech | |||
Title: | Trustee | |||
Address: The 1989 Leech Living Trust | ||||
3701 Brandy Rock Way | ||||
Redwood City, CA 94061 | ||||
Attn: | Ana Leech |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Matilda Nieri | ||
MATILDA NIERI | ||
Address: Matilda Nieri | ||
c/o Technofyn Associates L.L.C. | ||
4005 Miranda Avenue | ||
Suite 180 | ||
Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Alejandro A. Zaffaroni | ||
ALEJANDRO A. ZAFFARONI | ||
Address: | ||
Gonzalo M. Silveira | ||
c/o Technofyn Associates, LLC | ||
4005 Miranda Avenue, Suite 180 | ||
Palo Alto, CA ###-###-#### |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ALEXANDER PETER ZAFFARONI 12/29/88 TRUST | ||||
By: | /s/ Matilda Nieri | |||
Name: | Matilda Nieri | |||
Title: | Trustee | |||
Address: | ||||
Guillermo S. Surraco | ||||
c/o Technofyn Associates L.L.C. | ||||
4005 Miranda Avenue | ||||
Suite 180 | ||||
Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CHARLES ADAM ZAFFARONI 12/29/88 TRUST | ||||
By: | /s/ Matilda Nieri | |||
Name: | Matilda Nieri | |||
Title: | Trustee | |||
Address: | ||||
Guillermo S. Surraco | ||||
c/o Technofyn Associates L.L.C. | ||||
4005 Miranda Avenue | ||||
Suite 180 | ||||
Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Elisa Zaffaroni | ||
ELISA ZAFFARONI | ||
Address: | ||
Guillermo S. Surraco | ||
c/o Technofyn Associates L.L.C. | ||
4005 Miranda Avenue | ||
Suite 180 | ||
Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Leah Zaffaroni | ||
LEAH ZAFFARONI | ||
Address: | ||
Guillermo S. Surraco | ||
c/o Technofyn Associates L.L.C. | ||
4005 Miranda Avenue | ||
Suite 180 Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Donna L. Swanson | ||
DONNA L. SWANSON | ||
Address: Donna Swanson | ||
c/o Technofyn Associates L.C. | ||
4005 Miranda Avenue | ||
Suite 180 | ||
Palo Alto, CA 94304 |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
AFFYMETRIX, INC. | ||||
By: | /s/ Barbara A. Caufield/mcs | |||
Name: | Barbara A. Caufield | |||
Title: | Executive Vice President & General Counsel | |||
Address: | ||||
Affymetrix, Inc. | ||||
3380 Central Expressway | ||||
Santa Clara, CA 95051 | ||||
Attn: Greg Schiffman |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
SCHWEIZERHALL HOLDING AG SCHWEIZERHALI MANAGEMENT | ||||
By: | /s/ L. Von Bidder | |||
Name: | L. Von Bidder | |||
Title: | Chief Executive Officer | |||
By: | /s/ D. Kazi | |||
Name: | D. Kazi | |||
Title: | Investment Analyst | |||
Address: | ||||
c/o Mr. Luzi von Bidder | ||||
Nuschelerstrasse 30 | ||||
8023 Zurich | ||||
Switzerland |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ZAFFARONI FAMILY PARTNERSHIP, LP | ||||
By: | /s/ Alejandro Zaffaroni | |||
Name: | Alejandro Zaffaroni | |||
Title: | General and Limited Partner | |||
Address: | ||||
Gonzalo M. Silveira | ||||
c/o Technofyn Associates, LLC | ||||
4005 Miranda Avenue, Suite 180 | ||||
Palo Alto, CA ###-###-#### |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
COLUMBIA ACORN TRUST (f.k.a. | ||||
LIBERTY ACORN TRUST | ||||
By: /s/ Bruce H. Lauer | ||||
Name: | Bruce H. Lauer | |||
Title: Treasurer | ||||
Address: | ||||
227 West Monroe, Suite 3000 | ||||
Chicago, IL 60606 | ||||
Attention: Geoff Wilson |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CALIFORNIA EMERGING VENTURES, LLC | ||||
By: GSA Partners, LLC, its Manager | ||||
By: Grove Street Advisors, LLC, its Manager | ||||
By: /s/ Ann St. German | ||||
Name: | Ann St. German | |||
Title: | Member & CFO | |||
Address: | ||||
Grove Street Advisors | ||||
20 William Street, Suite 230 | ||||
Wellesley, MA 024581 | ||||
Attention: Ann St. German |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CSK FINANCE CO., LTD. | ||||
By: /s/ Syoji Wakita | ||||
Name: Syoji Wakita | ||||
Title: President | ||||
Address: | ||||
5th Floor, Reviera Minami Aoyama Bldg. | ||||
3-3-3 Minai-Aoyama, Minato-ku | ||||
Tokyo 107-0062 | ||||
Japan | ||||
Attn: Makoto Kaneshiro |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
CSK VENTURE CAPITAL CO., LTD., | ||||
As Investment Manager for CSK-VC Life | ||||
Science Investment Fund | ||||
By: /s/ Shunichi Ishimura | ||||
Name: Shunichi Ishimura | ||||
Title: President | ||||
Address: | ||||
5th Floor, Reviera Minami Aoyama Bldg. | ||||
3-3-3 Minai-Aoyama, Minato-ku | ||||
Tokyo 107-0062 | ||||
Japan | ||||
Attn: Makoto Kaneshiro |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
/s/ Guillermo Surraco | ||||
GUILLERMO SURRACO |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ALEJANDRO ZAFFARONI, TRUSTEE | ||||
OF ZAFFARONI RETIREMENT TRUST FBO | ||||
GONZALO M. SILVEIRA, U/A/D 1/1/02 | ||||
By: | /s/ Alejandro Zaffaroni | |||
Name: Alejandro Zaffaroni | ||||
Title: Trustee | ||||
Address: | ||||
Gonzalo M. Silveira | ||||
c/o Technofyn Associates, LLC | ||||
4005 Miranda Avenue, Suite 180 | ||||
Palo Alto, CA ###-###-#### |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ALEJANDRO ZAFFARONI, TRUSTEE OF | ||||
ZAFFARONI RETIREMENT TRUST FBO M. | ||||
LORETTE VIAUD, U/A/D 1/1/02 | ||||
By: | /s/ Alejandro Zaffaroni | |||
Name: Alejandro Zaffaroni | ||||
Title: Trustee | ||||
Address: | ||||
Gonzalo M. Silveira | ||||
c/o Technofyn Associates, LLC | ||||
4005 Miranda Avenue, Suite 180 | ||||
Palo Alto, CA ###-###-#### |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
ALSTERTOR PRIVATE LIFE GMBH & CO. | ||||
KG | ||||
By: | /s/ Erich Waller / Dieter Reinhardt | |||
Name: Waller/Reinhardt | ||||
Title: Managing Partners | ||||
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
MPM BIOEQUITIES MASTER FUND, LP | ||||
By: | MPM BioEquities GP, LP, its General Partner | |||
By: | MPM BioEquities GP, LLC its General | |||
Partner | ||||
By: | /s/ Kurt Von Emster | |||
Name: Kurt Von Emster | ||||
Title: Manager | ||||
Address: | ||||
MPM Capital, LP | ||||
601 Gateway Blvd. #350 | ||||
South San Francisco, CA 94080 | ||||
Attention: Kurt H. Von Emster |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement
PRIVATE LIFE BIOMED AG | ||||
By: | /s/ Marie M. Warburg / /s/ R. Gerlinger | |||
Name: Marie M. Warburg/R. Gerlinger | ||||
Title: Managing Director | ||||
Address: | ||||
Katja Nehrbaß | ||||
M.M. Warburrg & CO Schiffahrtstreuhand | ||||
Gesellschaft mit beschränkter Haftung | ||||
Ferdinandstraße 65-67 | ||||
D20095 Hamburg, Germany |
Amendment No. 1 to the Second Amended and Restated Registration Rights Agreement