PACIFIC BIOSCIENCES OF CALIFORNIA, INC. Contracts & Agreements

Letter Agreement, dated November 21, 2024, between the Company and SB Northstar LP (Filed With SEC on November 22, 2024)

Letter Agreement, dated November 7, 2024, between the Company and SB Northstar LP (Filed With SEC on November 7, 2024)

Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on June 20, 2024)

Form of Global Stock Option Agreement under the Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on June 20, 2024)

Form of Global Restricted Stock Unit Agreement under the Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on June 20, 2024)

Indenture, dated as of June 30, 2023, by and between Pacific Biosciences of California, Inc. and U.S. Bank Trust Company, National Association, as Trustee (Filed With SEC on June 30, 2023)

Letter Agreement, dated June 23, 2023, between the Company and Chimera Investment LLC (Filed With SEC on June 26, 2023)

Form of Performance-Based Restricted Stock Unit Award Agreement under the Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on February 28, 2023)

Underwriting Agreement, dated as of January 24, 2023 by and among Pacific Biosciences of California, Inc. and Goldman Sachs & Co. LLC, Morgan Stanley & Co. LLC, and Cowen and... (Filed With SEC on January 27, 2023)

Amended and Restated Development and Commercialization Agreement by and between the Registrant and Invitae Corporation dated June 24, 2022 (Filed With SEC on August 8, 2022)

Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on May 26, 2022)

Form of Global Stock Option Agreement under the Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on May 26, 2022)

Form of Global Restricted Stock Unit Agreement under the Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan, as amended (Filed With SEC on May 26, 2022)

Change in Control and Severance Agreement, by and between the Registrant and Denis Zaccarin, Ph.D. effective November 4, 2020 (Filed With SEC on May 6, 2022)

Pacific Biosciences of California, Inc. 2020 Inducement Equity Incentive Plan, as amended, and forms of agreement thereunder (Filed With SEC on November 19, 2021)

Omniome Equity Incentive Plan of Pacific Biosciences of California, Inc. and related forms of agreement thereunder (Filed With SEC on November 5, 2021)

Omniome Equity Incentive Plan of Pacific Biosciences of California, Inc. and related forms of agreement thereunder (Filed With SEC on September 20, 2021)

Letter Relating to Employment Terms by and between the Registrant and Michele Farmer effective May 17, 2021 (Filed With SEC on August 6, 2021)

Amendment to Development and Commercialization Agreement, dated as of June 3, 2021, by and between Pacific Biosciences of California, Inc. and Invitae Corporation (Filed With SEC on August 6, 2021)

Agreement and Plan of Merger and Plan of Reorganization among Pacific Biosciences of California, Inc., Apollo Merger Sub, Inc., Apollo Acquisition Sub, LLC, Omniome, Inc. and... (Filed With SEC on July 20, 2021)

Securities Purchase Agreement, dated as of July 19, 2021, by and between Pacific Biosciences of California, Inc. and each of the Investors (Filed With SEC on July 20, 2021)

Registration Rights Agreement, dated as of July 19, 2021, by and between Pacific Biosciences of California, Inc. and each of the Investors (Filed With SEC on July 20, 2021)

Pacific Biosciences of California, Inc. 2020 Inducement Equity Incentive Plan, as amended, and forms of agreement thereunder (Filed With SEC on April 19, 2021)

Form of Change in Control and Severance Agreement for executive officers (Filed With SEC on February 26, 2021)

Letter Relating to Employment Terms by and between the Registrant and Christian O. Henry effective September 14, 2020 (Filed With SEC on February 26, 2021)

Change in Control and Severance Agreement by and between the Registrant and Christian O. Henry effective September 14, 2020 (Filed With SEC on February 26, 2021)

Amended Change in Control and Severance Agreement by and between the Registrant and Christian O. Henry dated February 3, 2021 (Filed With SEC on February 26, 2021)

Letter Relating to Employment Terms by and between the Registrant and Mark Van Oene effective January 8, 2021 (Filed With SEC on February 26, 2021)

Letter Relating to Employment Terms by and between the Registrant and Peter Fromen effective January 8, 2021 (Filed With SEC on February 26, 2021)

Development and Commercialization Agreement by and between the Registrant and Invitae Corporation dated January 12, 2021 (Filed With SEC on February 26, 2021)

Exclusive License Agreement by and between the Registrant and Cornell Research Foundation, Inc., dated as of February 1, 2004 (Filed With SEC on February 26, 2021)

Indenture, dated February 16, 2021, between Pacific Biosciences of California, Inc. and U.S. Bank National Association, as Trustee (Filed With SEC on February 17, 2021)

Form of Indenture related to 1.50% Convertible Senior Notes due 2028 (Filed With SEC on February 10, 2021)

Investment Agreement, dated as of February 9, 2021, between Pacific Biosciences of California, Inc. and SB Northstar LP (Filed With SEC on February 10, 2021)

2020 Inducement Equity Incentive Plan and forms of agreement thereunder (Filed With SEC on December 4, 2020)

Underwriting Agreement, dated as of November 10, 2020 by and among Pacific Biosciences of California, Inc., Morgan Stanley & Co. LLC and Cowen and Company, LLC, and the Selling... (Filed With SEC on November 13, 2020)

Letter Relating to Employment Terms Susan G. Kim effective as of September 28, 2020 (Filed With SEC on November 3, 2020)

Change in Control and Severance Agreement by and between the Company and Susan G. Kim effective as of September 28, 2020 (Filed With SEC on November 3, 2020)

Underwriting Agreement, dated as of August 11, 2020 by and among Pacific Biosciences of California, Inc., Morgan Stanley & Co. LLC and Cowen and Company, LLC (Filed With SEC on August 14, 2020)

Pacific Biosciences of California, Inc. 2020 Equity Incentive Plan and related forms of agreement (Filed With SEC on August 5, 2020)

Description of Registrants securities registered under Section 12 of the Exchange Act (Filed With SEC on February 28, 2020)

Agreement by and among Pacific Biosciences of California, Inc., Illumina, Inc. and FC Ops Corp., dated January 2, 2020 (Filed With SEC on January 2, 2020)

Amendment No. 1 to Agreement and Plan of Merger dated as of November 1, 2018 (Filed With SEC on September 26, 2019)

Agreement and Plan of Merger, dated as of November 1, 2018, by and among Illumina, Inc., FC Ops Corp. and Pacific Biosciences of California, Inc (Filed With SEC on November 5, 2018)

Underwriting Agreement, dated as of September 11, 2018, by and among Pacific Biosciences of California, Inc., Cowen and Company, LLC and Cantor Fitzgerald & Co (Filed With SEC on September 14, 2018)

2010 Equity Incentive Plan forms of agreement (Filed With SEC on May 2, 2018)

2010 Outside Director Equity Incentive Plan forms of agreement (Filed With SEC on May 2, 2018)

First Amendment of Facility Agreement between the Registrant and Deerfield Private Design Fund II, L.P., Deerfield Private Design International II, L.P. and Deerfield Special... (Filed With SEC on February 26, 2018)

Underwriting Agreement, dated as of February 13, 2018, by and between Pacific Biosciences of California, Inc. and Cantor Fitzgerald & Co (Filed With SEC on February 15, 2018)

Fifth Lease Amendment Agreement by and between Pacific Biosciences of California, Inc. and Peninsula Innovation Partners, LLC, dated September 28, 2017 (Filed With SEC on November 2, 2017)

Letter Relating to Employment Terms by and between the Registrant and Kathy Ordoez effective October 30, 2017 (Filed With SEC on November 2, 2017)

Change in Control Severance Agreement by and between the Registrant and Kathy Ordoez effective October 30, 2017 (Filed With SEC on November 2, 2017)

FOURTH LEASE AMENDMENT AGREEMENT (Filed With SEC on August 2, 2017)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 15,419,354 Shares of Common Stock (par value $0.001 per share) Underwriting Agreement (Filed With SEC on June 20, 2017)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. CHANGE IN CONTROL SEVERANCE AGREEMENT (Filed With SEC on March 6, 2017)

CONFIDENTIAL TREATMENT REQUESTED CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN REDACTED AND HAVE BEEN SEPARATELY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION FIRST... (Filed With SEC on March 6, 2017)

THIRD LEASE AMENDMENT AGREEMENT (Filed With SEC on March 6, 2017)

CONFIDENTIAL TREATMENT REQUESTED CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN REDACTED AND HAVE BEEN SEPARATELY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION SECOND LEASE... (Filed With SEC on August 4, 2016)

LEASE AMENDMENT AGREEMENT (Filed With SEC on August 5, 2015)

CONFIDENTIAL TREATMENT REQUESTED CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN REDACTED AND HAVE BEEN SEPARATELY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION LEASE BY AND... (Filed With SEC on August 5, 2015)

A G R E E M E N T: (Filed With SEC on April 1, 2015)

[Signatures appear on following page] (Filed With SEC on April 1, 2015)

A G R E E M E N T: (Filed With SEC on April 1, 2015)

Pacific Biosciences of California, Inc. Controlled Equity OfferingSM Amendment No. 2 to Sales Agreement (Filed With SEC on February 3, 2015)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. CONTROLLED EQUITY OFFERINGSM AMENDMENT NO. 1 TO SALES AGREEMENT (Filed With SEC on November 12, 2013)

Warrant to Purchase Common Stock of Pacific Biosciences of California, Inc. (Filed With SEC on February 5, 2013)

FACILITY AGREEMENT (Filed With SEC on February 5, 2013)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on February 5, 2013)

SECURITY AGREEMENT (Filed With SEC on February 5, 2013)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. $30,000,000 of Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement (Filed With SEC on October 5, 2012)

SEPARATION AGREEMENT AND RELEASE (Filed With SEC on March 1, 2012)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. EMPLOYMENT AGREEMENT (Filed With SEC on March 1, 2012)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. CHANGE IN CONTROL SEVERANCEAGREEMENT (Filed With SEC on March 1, 2012)

Third Amendment to Industrial Lease (Filed With SEC on March 23, 2011)

First Amendment to Industrial Lease (Filed With SEC on March 23, 2011)

Lease Willow Park Menlo Park, California Willow Park Holding Company I, L.P., a Delaware limited partnership, as Landlord, and Pacific Biosciences of California, Inc., a Delaware... (Filed With SEC on March 23, 2011)

Lease Willow Park Menlo Park, California AMB Property, L.P., a Delaware limited partnership, as Landlord, and Pacific Biosciences of California, Inc., a Delaware corporation dba... (Filed With SEC on March 23, 2011)

Lease Willow Park Menlo Park, California Willow Park Holding Company II, L.P., a Delaware limited partnership, as Landlord, and Pacific Biosciences of California, Inc., a Delaware... (Filed With SEC on March 23, 2011)

COLLABORATION AGREEMENT between PACIFIC BIOSCIENCES OF CALIFORNIA, INC. and GEN-PROBEINCORPORATED Dated as of June 15, 2010 COLLABORATION AGREEMENT (Filed With SEC on October 22, 2010)

EXCLUSIVE LICENSE AGREEMENT (Filed With SEC on October 22, 2010)

LICENSE AGREEMENT (Filed With SEC on October 22, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. Shares of Common Stock UnderwritingAgreement (Filed With SEC on October 20, 2010)

COLLABORATION AGREEMENT between PACIFIC BIOSCIENCES OF CALIFORNIA, INC. and GEN-PROBEINCORPORATED Dated as of June 15, 2010 COLLABORATION AGREEMENT (Filed With SEC on October 19, 2010)

EXCLUSIVE LICENSE AGREEMENT (Filed With SEC on October 19, 2010)

EXCLUSIVE LICENSE AGREEMENT Between INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION Licensor And NANOFLUIDICS, INC. Licensee *** Confidential Treatment Requested (Filed With SEC on October 19, 2010)

COLLABORATION AGREEMENT between PACIFICBIOSCIENCES OF CALIFORNIA, INC. and GEN-PROBE INCORPORATED Dated as of June 15, 2010 COLLABORATION AGREEMENT (Filed With SEC on September 20, 2010)

EXCLUSIVE LICENSE AGREEMENT (Filed With SEC on September 20, 2010)

LICENSE AGREEMENT (Filed With SEC on September 20, 2010)

EXCLUSIVE LICENSE AGREEMENT Between INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION Licensor And NANOFLUIDICS, INC. Licensee *** Confidential Treatment Requested (Filed With SEC on September 20, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. EMPLOYMENT AGREEMENT (Filed With SEC on September 20, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. CHANGE IN CONTROL SEVERANCE AGREEMENT (Filed With SEC on September 20, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. FIFTH AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT TABLE OF CONTENTS (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. INDEMNIFICATION AGREEMENT (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2004 EQUITY INCENTIVE PLAN ADOPTED: MARCH 4, 2004 APPROVED BY STOCKHOLDERS: MARCH 4, 2004 AS AMENDED THROUGH AUGUST 12, 2010 (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2005 STOCK PLAN As amended through August 12, 2010 (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2010 EQUITY INCENTIVE PLAN (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2010 EMPLOYEE STOCK PURCHASE PLAN (Filed With SEC on August 16, 2010)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2010 OUTSIDE DIRECTOR EQUITY INCENTIVE PLAN (Filed With SEC on August 16, 2010)

AMENDED AND RESTATED LEASE BY AND BETWEEN MENLO BUSINESS PARK, LLC, LESSOR AND PACIFIC BIOSCIENCES OF CALIFORNIA, INC., LESSEE Menlo Business Park 1505 Adams Drive and 1525 OBrien... (Filed With SEC on August 16, 2010)

LEASE BY AND BETWEEN MENLO BUSINESS PARK, LLC, LESSOR AND PACIFIC BIOSCIENCES OF CALIFORNIA, INC., LESSEE Menlo Business Park 1605 Adams Drive, Suites A and C Menlo Park,... (Filed With SEC on August 16, 2010)

Industrial Lease Willow Park Menlo Park, California AMB Property, L.P., a Delaware limited partnership, as Landlord, and Pacific Biosciences of California, Inc., a Delaware... (Filed With SEC on August 16, 2010)

First Amendment to Lease Agreement (Filed With SEC on August 16, 2010)

Industrial Lease Willow Park Menlo Park, California AMB Property, L.P., a Delaware limited partnership, as Landlord, and Pacific Biosciences of California, Inc., a Delaware... (Filed With SEC on August 16, 2010)

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PACIFIC BIOSCIENCES OF CALIFORNIA, INC. Contracts & Agreements