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EX-10.50A 2 e500246_ex10-50a.htm LETTER AGREEMENT EFFECTIVE 1/1/02 10-K

Exhibit 10.50a

Certain confidential information contained in this document, marked by brackets and the word “Redacted” ([REDACTED]), has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 promulgated under the Securities Exchange Act of 1934, as amended.

December 22, 2004

Dennis A. Rossi Senior Vice President, General Manager, Genomics
Gene Logic Inc.
610 Professional Drive
Gaithersburg, MD 20879

  Re: Letter Agreement ("Letter Agreement") amending the terms of the Amended and Restated Agreement entered into by and between Gene Logic Inc. ("Gene Logic") and Affymetrix, Inc. ("Affymetrix") effective January 1, 2002, as amended ("Agreement")

Dear Mr. Rossi:

By entering into this Letter Agreement, Gene Logic and Affymetrix hereby agree to amend the Agreement as follows:

1. Revise section 2.29 to read:

  2.29 “Temporary Period” shall mean the period commencing on July 1, 2003 and continuing through December 31, 2005.

2. The Price List attached as Exhibit I-1 to the amendment dated September 23, 2003, as amended by the letter dated April 4, 2004, shall continue to apply to orders placed during the remaining portion of the Temporary Period. For convenience, a copy of such Price List is attached hereto as Exhibit A.

3. After Section 5.1, insert new sections 5.1.1 through 5.1.4 as follows:

5.1.1.        Notwithstanding Section 5.1 above and in lieu of the annual payment of $4,000,000 for 2005 otherwise required thereby, during the period commencing on January 1, 2005, and continuing through December 31, 2005, Gene Logic shall pay to Affymetrix a fee of $500,000, payable in $125,000 increments due at the end of each calendar quarter during such period.

5.1.2.        Gene Logic agrees to purchase the following products at the following prices, to be shipped to the address set forth above by Affymetrix on or before December 31, 2004. Such purchase shall not count toward Gene Logic’s 2005 purchase commitment described in Section 5.1.3 below.

Description Quantity Unit price* Subtotal**
Human Genome U133 2.0 Plus array [REDACTED] $[REDACTED]/array $[REDACTED]
IVT kits [REDACTED] $[REDACTED]/kit $[REDACTED]
Rat Genome 230 2.0 arrays [REDACTED] $[REDACTED]/array $[REDACTED]
TOTAL PRICE**: $500,080

  *Theseprices do not include use for Services or Tox Services; if such products are intended for use, or are used, for Services or Tox Services, the pricing in Exhibit I-1 (as amended) shall apply instead.

  **Excludes freight and handling.

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5.1.3.        Gene Logic agrees to purchase $9,500,000 worth of Probe Arrays, reagents, services under maintenance and service agreements and/or instrumentation during the period commencing on January 1, 2005, and continuing through December 31, 2005, to be shipped (or in the case of services to be provided) by Affymetrix on or before December 31, 2005. Probe Arrays purchased for database upgrades/re-runs and priced at the volume discount upgrade\re-run pricing attached hereto as Exhibit B shall count toward such purchase commitment. If Gene Logic fails to purchase such amount of such products by December 31, 2005 (for shipment within 2005), then Gene Logic shall pay upon receipt of Affymetrix’ invoice the difference between $9,500,000 and the amount of such purchases actually made by Gene Logic in 2005.

5.1.4.        Gene Logic agrees to purchase one GeneChip Array Station for $[REDACTED]and one GeneChipHT array scanner for $[REDACTED] (such prices exclude freight and handling) during the period commencing on January 1, 2005, and continuing through December 31, 2005, for shipment by Affymetrix on or before December 31, 2005. Such purchases shall count toward Gene Logic’s 2005 purchase commitment described in Section 5.1.3 above.

Unless otherwise modified herein, all capitalized terms used in this letter shall have the meaning ascribed to them in the Agreement. All other aspects of the Agreement remain unchanged and in full force and effect.

AGREED AND ACKNOWLEDGED:

Affymetrix, Inc.


BY: /S/ Barbara A Caulfield
——————————————

Name: Barbara A. Caulfield

Title: Executive Vice President and General Counsel


Date: December 22, 2004
Gene Logic Inc.


BY: /S/ Dennis A. Rossi
——————————————

Name: Dennis Ross

Title: Senior Vice President and General
          Manager, Genomics Business Unit

Date: December 22, 2004

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Exhibit A
Temporary Period Price List
Standard Probe Arrays
Per array pricing in US Dollars

    A B
Part Number Array Name Standard
Pricing
Service Provider
Supplemental Charge
Human Array      
900466,900467
900470
Human Genome U133 2.0 Plus [REDACTED] [REDACTED]
900468, 900469
900471
Human Genome U133A 2.0 [REDACTED] [REDACTED]
900366, 900367, 900368,
900369, 900370, 900444
510681, 510682
Human Genome U133A or U133B
array
[REDACTED] [REDACTED]
900303, 900304 Human GenomeU95Av2 Array [REDACTED] [REDACTED]
900376, 900377 Human Genome Focus Array [REDACTED] [REDACTED]
       
Rat Array      
900505, 900506, 900507 Rat Genome 230 2.0 [REDACTED] [REDACTED]
900404, 900405, 900406,
900407, 900408, 900442
Rat Expression Array 230A
or 230B
[REDACTED] [REDACTED]
900249, 900286
510338
Rat Genome U34A Array [REDACTED] [REDACTED]
900250, 900251, 900287, 900288
510339, 510340
Rat Genome U34B or U34C
Array
[REDACTED] [REDACTED]
       
Mouse Array      
900495, 900496
900497
Mouse Genome 430 2.0 [REDACTED] [REDACTED]
900498, 900499
900500
Mouse Genome 430A 2.0 [REDACTED] [REDACTED]
900412, 900413, 900414,
900415, 900416, 900443
Mouse Expression Array 430A
or 430B
[REDACTED] [REDACTED]
900343, 900344
510568
Murine Genome U74Av2 Array [REDACTED] [REDACTED]
900357, 900358, 900359, 900360
510570, 510571
Murine Genome U74Bv2 or U74Cv2 Array [REDACTED] [REDACTED]
       
900489, 900490 Canine [REDACTED] [REDACTED]
       
520049 Human X3P [REDACTED] [REDACTED]
       
900487, 900488 Zebrafish [REDACTED] [REDACTED]
       
900491, 900492 Xenopus [REDACTED] [REDACTED]
       
Customexpress Array      
510685 Canine Array [REDACTED] [REDACTED]

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Exhibit B Database upgrade/re-run pricing

  New Samples Database Upgrade/Rerun
  Std Volume Based (Committed)
2005 Proposed Pricing   10,000 15,000 20,000
Cartridge Arrays        
Human Genome U133 2.0 Plus $[REDACTED] $[REDACTED] $[REDACTED] $[REDACTED]
Rat Genome 230 2.0 $[REDACTED] $[REDACTED] $[REDACTED] $[REDACTED]
Mouse Genome 430 2.0 $[REDACTED] $[REDACTED] $[REDACTED] $[REDACTED]
HTA Peg Arrays        
Total Peg Arrays and Reagents (Price Per Well) $[REDACTED] $[REDACTED] $[REDACTED] $[REDACTED]

For accounting purposes, Gene Logic needs to notify Affymetrix by January 15, 2005, which volume bracket Gene Logic is committing to for database upgrade/re-runs for 2005. Gene Logic shall indicate on its purchase orders which Probe Arrays will be used for database upgrades/re-runs.

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