FIRST AMENDMENT TO REVOLVING CREDIT AGREEMENT Between: THEKOSKI FAMILY LIMITED PARTNERSHIP, a Texas Limited Partnership as Lender and ORAGENICS, Inc., a Florida Corporation as Borrower. Additional Loan Amount: $500,000.00 Date: January 24, 2011 FIRST AMENDMENT TO REVOLVING CREDIT AGREEMENT

Exhibit 10.2

FIRST AMENDMENT TO

REVOLVING CREDIT AGREEMENT

Between:

THE KOSKI FAMILY LIMITED PARTNERSHIP,

a Texas Limited Partnership

as “Lender”

and

ORAGENICS, Inc.,

a Florida Corporation

as “Borrower”.

Additional Loan Amount: $500,000.00

Date: January 24, 2011

FIRST AMENDMENT TO

REVOLVING CREDIT AGREEMENT

THIS FIRST AMENDMENT to the REVOLVING CREDIT AGREEMENT (the “Amendment”) is made and entered into as of the 24^th day of January, 2011, by and between THE KOSKI FAMILY LIMITED PARTNERSHIP, a Texas Limited Partnership (“Lender”), having an address for the purposes hereof of 3525 Turtle Creek Boulevard, Unit 19-B, Dallas, Texas 75219 and ORAGENICS, INC., a Florida corporation (“Borrower”), having an address of 3000 Bayport Drive, Suite 685, Tampa, Florida 33607.

W I T N E S S E T H:

WHEREAS, Borrower applied to Lender for a revolving loan in the principal amount of up to $2,000,000.00, upon and subject to the terms and conditions hereof;

WHEREAS, Lender and Borrower entered into the Revolving Credit Agreement on July 30, 2010 (the “Agreement”) pursuant to which the Borrower could borrow up to $2,000,000;

WHEREAS, Borrow drew down $1,000,000 under the Agreement on September 13, 2010 and drew down the remaining $1,000,000 in available funds under the Agreement on November 8, 2010; and

WHEREAS, Borrower and Lender hereby seek to enter into this Amendment to increase the availability under the original Agreement by an additional $500,000.

NOW, THEREFORE, for and in consideration of the sum of $10.00 and for other good and valuable considerations, the receipt and sufficiency of which are hereby acknowledged, Lender and Borrower agree as follows:

In Sections 2.01 and 2.02 “$2,000,000” is replaced with “2,500,000.”

IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed and delivered as of the date first above written.