AMENDMENT TO INVESTMENT AGREEMENT

Exhibit 10.1

AMENDMENT TO INVESTMENT AGREEMENT

This Amendment to the Investment Agreement (this “Amendment”) is made as of June 1, 2017 (the “Effective Date”), by and between Opiant Pharmaceuticals, Inc. (formerly known as Lightlake Therapeutics Inc.), a Nevada corporation (“Company”) and Ernst Welmers (the “Investor”). Capitalized terms used but not defined herein have the meanings given to them in the Investment Agreement (as defined below).

RECITALS

WHEREAS, the parties entered into that certain Investment Agreement, dated as of May 15, 2014 (and clarified in a letter agreement dated October 15, 2014) (the “Investment Agreement”), pursuant to which Investor agreed to invest certain funds into the Company, and the Company has agreed to assign the Investor the right to receive a certain amount of the financial return produced by the Product in accordance with the terms and conditions set forth therein;

WHEREAS, the Company is currently planning on developing a specific product that is not for the treatment of a specific addiction, that the Company internally references under the name “DAVINCI” and that is undergoing a study during Q1 2017 (“DAVINCI”);

WHEREAS, the parties desire to amend the Investment Agreement to provide for the Company’s right to buyback the Interest or any portion of the Interest from the Investor;

WHEREAS, in consideration of the Company’s right to buyback the Interest or any portion of the Interest from the Investor, the Company is willing to pay the Investor the DAVINCI Interest and the Payment (both terms as defined herein); and

WHEREAS, pursuant to Section 6.4 of the Investment Agreement, the parties desire to amend, modify and supplement the Investment Agreement in the manner specified in this Amendment.

NOW, THEREFORE, for other good and valuable consideration, the receipt and adequacy of which are hereby acknowledged, the parties hereby agree as follows:

1.       Amendment to Article 1 of the Investment Agreement. Article 1 of the Investment Agreement is hereby amended by adding a new Section 1.2 thereto, immediately after Section 1.1, as follows:

“1.2          Notwithstanding any other provisions of this Agreement, from the Effective Date until five (5) years from the date of the Investment, the Company shall have the right to buyback the Interest or any portion of the Interest from the Investor by providing written or electronic notice to the Investor. Any such notice shall include the percentage amount of the Interest to be bought back by the Company, and such notice shall also include the dollar amount invested by the Investor that equals the percentage amount of the Interest to be bought back by the Company based on a rate of one and a half percent (1.5%) per Three Hundred Thousand Dollars (US$300,000.00) of investment (the “Buyback Amount”). In the event that such notice is provided within three and one quarter (3¼) years of the date of the Investment, then the Company shall pay the Investor one point eight (1.8) times the Buyback Amount within ten (10) business days of providing such notice. In the event that such notice is provided after three and one quarter (3¼) years from the date of the Investment and no later than five (5) years from the date of the Investment, then the Company shall pay the Investor three point fifteen (3.15) times the Buyback Amount within ten (10) business days of providing such notice. Upon the Company’s paying to the Investor the Buyback Amount with respect to the Interest or any portion of the Interest, such Interest or portion of the Interest, as appropriate, shall be deemed either extinguished or transferred or sold back to the Company, at the Company’s direction, and have no further legal effect and the Investor shall have no rights with respect to such amount of Interest bought back by the Company.”

2.       As consideration for the amendment made to the Investment Agreement as provided herein, the Company shall pay the Investor as follows:

3.       The Company previously entered into a Purchase and Sale Agreement (the “SWK Agreement”) with SWK Funding LLC (“SWK”) pursuant to which, inter alia the Company sold SWK a portion of the royalties the Company could have received pursuant to the License Agreement dated December 15, 2014 (the “Adapt Agreement”), by and between the Company and Adapt Pharma Operations Limited, an Irish limited company (“Adapt”). The transactions contemplated by the SWK Agreement are referred to herein collectively as the “SWK Transaction.” The Company and the Investor hereby agree that upon the Company receiving subsequent to the Effective Date at least $3 million from SWK pursuant to the SWK Transaction and/or from Adapt pursuant to the Adapt Agreement, fifty percent (50%) of all actual amounts received by the Company from SWK pursuant to the SWK Transaction shall be deemed “pre-tax revenue received by the Company that was derived from the sale of the Product” and therefore such amount shall be used in determination of the Net Profit.

4.       This Amendment and the Investment Agreement, attached as Exhibit A, constitute the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior agreements and understanding between the parties (whether written or oral) relating thereto. No modification shall be effective unless made in writing and signed by a duly authorized representative of each party.

5.       All other terms and conditions of the Investment Agreement shall remain in full force and effect.

6.       This Amendment may be executed in counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. This Amendment may be executed by facsimile or electronically transmitted signatures and such signatures shall be deemed to bind each party hereto as if they were original signatures.

7.       This Amendment, and any interpretation, dispute or controversy arising out of this Amendment, shall be governed by and construed in accordance with the laws of the State of Nevada without regard to the conflicts of laws principles thereof.

IN WITNESS WHEREOF the parties hereto have caused this Amendment to be executed by their duly authorized officers as of the day and year first above written.

EXHIBIT A

Investment Agreement, dated May 15, 2014, and letter agreement clarifying the Investment Agreement, dated October 15, 2014.