obtain regulatory approval for our PharmacoSurgery product candidates OMS103HP, OMS302 and OMS201

Exhibit 10.32

AMENDMENT dated 8 May 2007

of the

EXCLUSIVE LICENSE AND SPONSORED RESEARCH AGREEMENT
dated 31 October 2005

By and between

MEDICAL RESEARCH COUNCIL and OMEROS CORPORATION

     This is an amendment (this “Amendment”) effective 8 May 2007 of the Exclusive License and Sponsored Research Agreement between Medical Research Council (“MRC”) and Omeros Corporation (“Omeros”) dated 31 October 2005 (“the Agreement”). All initial capitalized terms used herein below shall have the same definition as set forth in the Agreement.

     Section 2.5 of the Agreement provides for payments for Sponsored Research during each year of a three year Sponsored Research Term to be paid on a quarterly basis, with twenty five percent (25%) of the annual amount to be paid each quarter. In as much as the third year of the Sponsored Research Terms comprises only a ten (10) month Sponsored Research period, not withstanding the payment schedule set forth in Section 2.5 of the Agreement, Omeros and MRC hereby agree that payments during the third year of the Sponsored Research Term shall be due and payable as follows:

Quarterly Payment		Amount		Due Date
1st		[†]		1 November 2007
2nd		[†]		1 March 2008
3rd		[†]		1 July 2008
4th		[†]		31 August 2008

     The total amount of funding for the third year of the Sponsored Research Term [†], as well as each party’s right to terminate the Agreement early in accordance with the provisions of Section 14 of the Agreement, and all other terms of the Agreement remain unchanged and in force.

     This Amendment is accepted and acknowledged by each party, as of the effective date set forth herein above, through the signature of its authorized representatives below:

MEDICAL RESEARCH COUNCIL						OMEROS CORPORATION
By:		/s/ Anne Marie Coriat				By:		/s/ Gregory A. Demopulos
Name:		Anne Marie Coriat PhD				Name:		Gregory A. Demopulos, M.D.
Title:		Head of MRC Centre, Oxforshire				Title:		Chairman & CEO
		MRC Centre Oxfordshire
		MRC Harwell
		DIDCOT
		Oxfordshire OX11 0RD
		Tel: 01235 841000