Novan, Inc. | Business Contracts

Form of Securities Purchase Agreement, dated June 9, 2022, by and between the Company and the purchaser identified therein (Filed With SEC on June 10, 2022)

Placement Agent Agreement, dated June 9, 2022, by and between the Company and Oppenheimer & Co. Inc (Filed With SEC on June 10, 2022)

Master Manufacturing and Supply Agreement, dated August 16, 2018, by and between DPT Laboratories, Ltd. and EPI Health, LLC (as successor-in-interest to Allergan Sales, LLC) (Filed With SEC on May 16, 2022)

Novan Patent and Know-How License Agreement, dated December 29, 2015, by and between Novan, Inc. and KNOW Bio, LLC (Filed With SEC on May 16, 2022)

Non-Employee Director Compensation Policy (Filed With SEC on May 16, 2022)

Lease, dated as of January 18, 2021, by and between Novan, Inc. and Copper II 2020, LLC, and as amended by the First Amendment to Lease as of March 18, 2021 (Filed With SEC on May 11, 2021)

Form of Pre-Funded Warrant (Filed With SEC on June 10, 2022)

Form of Common Warrant (Filed With SEC on June 10, 2022)

UNC Sublicense Agreement, dated December 29, 2015, by and between Novan, Inc. and KNOW Bio, LLC (Filed With SEC on May 16, 2022)

Second Amendment, dated April 12, 2016, to the Amended, Restated and Consolidated License Agreement between The University of North Carolina and Novan, Inc., dated as of June 27,... (Filed With SEC on May 16, 2022)

Amended, Restated and Consolidated License Agreement between The University of North Carolina and Novan, Inc., dated as of June 27, 2012, and as amended on November 30, 2012 (Filed With SEC on May 16, 2022)

Assignment and License Agreement, effective as of August 3, 2009, by and between Aspect Pharmaceuticals, LLC and EPI Health, LLC (as successor-in-interest to Vicept Therapeutics,... (Filed With SEC on May 16, 2022)

Amended and Restated Promotion and Collaboration Agreement, effective as of January 1, 2022, by and between MC2 Therapeutics Limited and EPI Health, LLC (Filed With SEC on May 16, 2022)

Employment Agreement, dated March 11, 2022, by and between Novan, Inc. and John Donofrio (Filed With SEC on May 16, 2022)

Form of Award Agreement Awarding Restricted Stock Units under the Novan, Inc. 2016 Incentive Award Plan (Filed With SEC on May 16, 2022)

Unit Purchase Agreement, dated as of (Filed With SEC on March 11, 2022)

Equity Distribution Agreement, dated (Filed With SEC on March 11, 2022)

Secured Promissory Note and Security Agreement, dated as of (Filed With SEC on March 11, 2022)

Development Funding and Royalties Agreement, dated May 4, 2019, by and between Novan, Inc. and Ligand Pharmaceuticals Incorporated (Filed With SEC on February 18, 2022)

Royalty and Milestone Payments Purchase Agreement, dated April 29, 2019, by and between Novan, Inc. and Reedy Creek Investments LLC (Filed With SEC on February 18, 2022)

Fifth Amendment, dated September 24, 2021, to the Amended, Restated and Consolidated License Agreement between the University of North Carolina and Novan, Inc., dated as of June... (Filed With SEC on February 18, 2022)

Fourth Amendment, dated November 26, 2018, to the Amended, Restated and Consolidated License Agreement between the University of North Carolina and Novan, Inc., dated as of June... (Filed With SEC on February 18, 2022)

Employment Agreement, dated November 1, 2021, by and between Novan, Inc. and Brian M. Johnson (Filed With SEC on February 18, 2022)

Description of Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 18, 2022)

First Amendment to Amended and Restated Employment Agreement, dated November (Filed With SEC on November 10, 2021)

First Amendment to Employment Agreement, dated August 11, 2021, by and between Novan, Inc. and John M. Gay (Filed With SEC on August 12, 2021)

Underwriting Agreement, dated June 17, 2021, by and between the Company and Cantor Fitzgerald & Co (Filed With SEC on June 21, 2021)

Novan, Inc. Tangible Stockholder Return Plan, as amended and restated (Filed With SEC on May 25, 2021)

Novan, Inc. 2016 Incentive Award Plan, as amended and restated (Filed With SEC on May 25, 2021)

Novan, Inc. 2016 Incentive Award Plan, as amended and restated (Filed With SEC on May 6, 2021)

Non-Employee Director Compensation Policy (Filed With SEC on March 2, 2021)

Description of Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 24, 2021)

Form of Director and Executive Officer Indemnification Agreement (Filed With SEC on October 30, 2020)

Lease Termination Agreement, dated July 16, 2020, by and between Novan, Inc. and Durham Hopson, LLC (Filed With SEC on October 30, 2020)

Letter Amendment, dated (Filed With SEC on October 30, 2020)

Employment Agreement, dated September 23, 2020, by and between Novan, Inc. and John M. Gay (Filed With SEC on September 24, 2020)

Non-Employee Director Compensation Policy (Filed With SEC on September 24, 2020)

Common Stock Purchase Agreement, dated July 21, 2020, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on July 22, 2020)

Registration Rights Agreement, dated July 21, 2020, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on July 22, 2020)

Common Stock Purchase Agreement, dated June 15, 2020, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on June 17, 2020)

Registration Rights Agreement, dated June 15, 2020, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on June 17, 2020)

Paycheck Protection Program Term Note, dated April 22, 2020, in favor of PNC Bank, National Association (Filed With SEC on April 23, 2020)

Form of Pre-Funded Warrant (Filed With SEC on March 26, 2020)

Securities Purchase Agreement, dated March 24, 2020, by and between the Company and each Purchaser thereto (Filed With SEC on March 26, 2020)

Form of Placement Agent Warrant (Filed With SEC on March 26, 2020)

Underwriting Agreement, dated February 27, 2020, by and between the Company and H.C. Wainwright & Co., LLC (Filed With SEC on March 3, 2020)

Form of Common Warrant (Filed With SEC on March 3, 2020)

Form of Pre-Funded Warrant (Filed With SEC on March 3, 2020)

Form of Underwriter Warrant (Filed With SEC on March 3, 2020)

Stock Appreciation Right Grant Notice and Agreement between Novan, Inc. and Paula Brown Stafford (Filed With SEC on February 24, 2020)

Amended and Restated Employment Agreement dated December 17, 2019, by and between Novan, Inc. and Paula Brown Stafford (Filed With SEC on February 24, 2020)

Description of Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on February 24, 2020)

Common Stock Purchase Agreement, dated August 30, 2019, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on September 5, 2019)

Registration Rights Agreement, dated August 30, 2019, between Novan, Inc. and Aspire Capital Fund, LLC (Filed With SEC on September 5, 2019)

Development Funding and Royalties Agreement, dated May 4 2019, by and between Novan, Inc. and Ligand Pharmaceutical Incorporated (Filed With SEC on August 13, 2019)

Royalty and Milestone Payments Purchase Agreement, dated April 29, 2019, by and between Novan, Inc. and Reedy Creek Investments LLC (Filed With SEC on August 13, 2019)

Novan, Inc. 2016 Incentive Award Plan, as amended and restated (Filed With SEC on August 6, 2019)

Third Amendment, dated November 1, 2018, to the Amended, Restated and Consolidated License Agreement between The University of North Carolina and Novan, Inc., dated as of June 27,... (Filed With SEC on March 27, 2019)

Consulting Agreement, dated January 29, 2019, by and between Novan, Inc. and Jeff N. Hunter (Filed With SEC on March 27, 2019)

Separation and General Release Agreement, dated January 29, 2019, by and between Novan, Inc. and Jeff N. Hunter (Filed With SEC on March 27, 2019)

Second Amendment, dated November 2, 2018, to the UNC Sublicense Agreement, dated December 29, 2015, by and between Novan, Inc. and KNOW Bio, LLC (Filed With SEC on March 27, 2019)

Second Amendment, dated November 2, 2018 to the Novan Patent and Know-How License Agreement, dated December 29, 2015, by and between Novan, Inc. and KNOW Bio, LLC (Filed With SEC on March 27, 2019)

Employment Agreement, dated January 29, 2019, by and between Novan, Inc. and Paula Brown Stafford (Filed With SEC on March 27, 2019)

Separation and General Release Agreement, dated January 4, 2019, by and between Novan, Inc. and Nathan Stasko (Filed With SEC on January 7, 2019)

Novan, Inc. (64)