Independent Auditors’ Report and Financial Statements of Cytovia, Inc. for 1998 and 1999
Summary
This document is an independent auditors’ report by Ernst & Young LLP for Cytovia, Inc., a development stage company. It includes audited financial statements for the years ending December 31, 1998 and 1999. The report confirms that the financial statements fairly present the company’s financial position and results in accordance with U.S. accounting standards. The document also provides detailed balance sheets, statements of operations, stockholders’ equity, and cash flows for the specified periods.
EX-2.3 4 ex-2_3.txt EXHIBIT 2.3 Exhibit 2.3 Report of Independent Auditors The Board of Directors Cytovia, Inc. We have audited the accompanying balance sheets of Cytovia, Inc. (a development stage company) as of December 31, 1999 and 1998 and the related statements of operations, stockholders' equity and cash flows for the year ended December 31, 1999 and the periods from January 9, 1998 (inception) through December 31, 1998 and 1999. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits in accordance with auditing standards generally accepted in the United States. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of Cytovia, Inc. (a development stage company) at December 31, 1999 and 1998, and the results of its operations and its cash flows for the year ended December 31, 1999 and the periods from January 9, 1998 (inception) through December 31, 1998 and 1999, in conformity with accounting principles generally accepted in the United States. /s/ Ernst & Young LLP March 24, 2000 1 Cytovia, Inc. (a development stage company) Balance Sheets
SEE ACCOMPANYING NOTES. 2 Cytovia, Inc. (a development stage company) Statements of Operations
SEE ACCOMPANYING NOTES. 3 Cytovia, Inc. (a development stage company) Statement of Stockholders' Equity
SEE ACCOMPANYING NOTES. 4 Cytovia, Inc. (a development stage company) Statements of Cash Flows
SEE ACCOMPANYING NOTES. 5 Cytovia, Inc. (a development stage company) Notes to Financial Statements December 31, 1999 1. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES GENERAL Cytovia, Inc. (the "Company") was formed out of a general partnership in December 1997 between CoCensys, Inc. and a founding partner. On January 9, 1998 the general partnership was dissolved and the Company was incorporated. Cytovia, Inc. is focused on discovering and developing small-molecule therapeutics that modulate key cellular signal pathways involved in programmed cell death, also known as apoptosis. Cytovia has developed a proprietary whole cell screening technology to screen compound libraries and already has uncovered several classes of novel small molecule drug compounds for the treatment of a wide range of diseases including drug resistant cancers, myocardial infarction, stroke, liver failure and other degenerative diseases. CASH, CASH EQUIVALENTS, AND SHORT-TERM INVESTMENTS The Company considers instruments purchased with an original maturity of three months or less to be cash equivalents. Short-term investments consist of highly liquid debt instruments. Management has classified the Company's short-term investments as available-for-sale securities in the accompanying financial statements. Available-for-sale securities are carried at fair value, with the unrealized gains and losses, net of tax, reported as a separate component of stockholders' equity. PROPERTY AND EQUIPMENT Property and equipment are recorded at cost. Depreciation is computed using the straight-line method over the estimated useful lives, generally three to ten years. Maintenance and repair costs are charged to expense as incurred. 6 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 1. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) ACCOUNTING STANDARD ON IMPAIRMENT OF LONG-LIVED ASSETS In accordance with Statement of Financial Accounting Standards ("SFAS") No. 121, ACCOUNTING FOR IMPAIRMENT OF LONG-LIVED ASSETS AND FOR LONG-LIVED ASSETS TO BE DISPOSED OF, the Company regularly evaluates its long-lived assets for indicators of possible impairment and records impairment losses when indicators of impairment are present and the estimated undiscounted cash flows to be generated by those assets are less than the assets' carrying amounts. While the Company's current and historical operating and cash flow losses are indicators of impairment, the Company believes the future cash flows to be received from the long-lived assets will exceed the assets' carrying value, and accordingly the Company has not recognized any impairment losses through December 31, 1999. STOCK-BASED COMPENSATION As permitted by SFAS No. 123, ACCOUNTING FOR STOCK-BASED COMPENSATION, the Company has elected to follow Accounting Principles Board Opinion No. 25, ACCOUNTING FOR STOCK ISSUED TO EMPLOYEES, ("APB 25") and related Interpretations in accounting for its employee stock options. Under APB 25, if the exercise price of the Company's employee stock options equals or exceeds the fair value of the underlying stock on the date of grant, no compensation expense is recognized. Options issued to non-employees are recorded at their fair value in accordance with SFAS No. 123 and EITF 96-18 and recognized over the related service period. RESEARCH AND DEVELOPMENT COSTS Research and development costs are expensed as incurred. USE OF ESTIMATES The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. 7 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 1. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) COMPREHENSIVE INCOME In accordance with SFAS No. 130, REPORTING COMPREHENSIVE INCOME, all components of comprehensive income (loss), including net income (loss), are reported in the financial statements in the period in which they are recognized. Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. Net income (loss) and other comprehensive income (loss), including unrealized gains and losses on investments, are reported, net of their related tax effect, to arrive at comprehensive income (loss). 2. SHORT-TERM INVESTMENTS The following is a summary of available-for-sale securities as of December 31, 1999:
The following is a summary of available-for-sale securities as of December 31, 1998:
As of December 31, 1999, all of the available-for-sale securities have a maturity of less than one year. 8 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 3. PROPERTY AND EQUIPMENT Property and equipment consist of the following at December 31:
Depreciation and amortization amounted to $416,444 and $42,051 for the year ended December 31, 1999 and the period from January 9, 1998 (inception) through December 31, 1998, respectively. Depreciation and amortization expense amounted to $458,495 for the period from January 9, 1998 (inception) through December 31, 1999. 4. STOCKHOLDERS' EQUITY At December 31, 1999, convertible preferred stock authorized and outstanding is as follows:
9 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 4. STOCKHOLDERS' EQUITY (CONTINUED) In the event of a liquidation of the Company, preferred stockholders are entitled to a liquidation preference of $9.31 per share for Series A, $5.37 per share for Series A2 and $16.09 per share for Series B, plus any declared and unpaid dividends as such shares. After distribution to the Series A, A2 and B preferred stockholders, the remaining assets of the Company shall be distributed to the holders of Series A1 preferred and holders of common stock in proportion to the number of shares of Series A1 preferred and common stock then held. In April 1999, the Board of Directors of the Company approved a 2-for-1 stock split of the common stock of the Company. All amounts have been restated to reflect this split as if it had occurred at the inception of the Company. In March 1998, the Company issued 1,084,860 shares of Series A convertible preferred stock for $9.31 per share with gross proceeds to the Company of $10,100,047. In July 1998, the Company issued 124,301 shares of Series B convertible preferred stock for $16.09 per share with gross proceeds to the Company of $2,000,003. In May 1999, CoCensys, Inc., converted its 440,000 shares of common stock in the Company to 450,000 shares of Series A1 convertible preferred stock. As consideration for the conversion, the companies renegotiated a license agreement in effect between them. Originally, the license agreement called for CoCensys to receive 50% of amounts received by the Company for licensing rights under the agreement to products which treat central nervous systems (CNS) disorders, and 12% of amounts received for licensing rights under the agreement to products which treat other indications. In exchange for the conversion, this agreement was amended so that CoCensys would receive 15% of amounts received by the Company for licensing rights to any products under the agreement regardless of indication. In December 1999, the Company issued 558,660 shares of Series A2 convertible preferred stock for $5.37 per share with gross proceeds to the Company of $3,001,615. 10 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 4. STOCKHOLDERS' EQUITY (CONTINUED) Each share of convertible preferred stock is convertible at any time, at the option of the holder, into common stock, on a one-to-one basis, adjusted for stock splits and subject to certain antidilution adjustments. In addition, there is mandatory conversion of each series of convertible preferred stock upon consummation of an initial public offering of common stock with aggregate gross proceeds to the Company in excess of $15 million and a share price which equals two and one-half times the purchase price per share. Each series of convertible preferred stock is also convertible upon a vote of majority of the holders of the outstanding shares of that series of convertible preferred stock. WARRANTS As of December 31, 1999 and 1998, the Company had outstanding warrants to purchase 4,972 and 3,418 shares of Series B preferred stock at a price of $16.09 per share. The warrants are exercisable until August 6, 2005 or 3 years after closing of an initial public offering, whichever is longer. STOCK OPTION PLAN In March 1998, the Company adopted the 1998 Equity Incentive Plan (the "Plan") which provides for the grant of incentive and nonstatutory stock options and other cash and stock based awards to employees, directors or consultants of the Company. The Plan authorizes the Company to issue up to 457,688 shares of common stock as amended. The Plan provides that incentive stock options will be granted at no less than the fair value of the Company's common stock as determined by the board of directors at the date of the grant. The options generally vest and become exercisable over a period of four years. Options expire no more than ten years after the date of grant, or earlier if the employment terminates. 11 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 4. STOCKHOLDERS' EQUITY (CONTINUED) The following table summarizes stock option activity:
As of December 31, 1999, options to purchase 123,641 shares are exercisable and 48,871 shares are available for future grant under the Plan. As of December 31, 1999, the weighted-average remaining contractual life was approximately 9.07 years. Pro forma information regarding net loss is required by SFAS No. 123, and has been determined as if the Company had accounted for its employee stock options under the fair value method prescribed by SFAS No. 123. The fair value of these options was estimated at the date of grant using the minimum value method with the following weighted average assumptions for 1999 and 1998: risk-free interest rate of 5.5%; no annual dividends; and an expected option life of four years. The weighted-average fair value of the options granted during 1999 and 1998 was $.80 and $.11, respectively. The effect of applying the minimum value method of SFAS No. 123 to options granted in 1999 and 1998 did not result in a pro forma net loss that is materially different from the amount reported. Accordingly, such pro forma information is not presented herein. 12 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 4. STOCKHOLDERS' EQUITY (CONTINUED) COMMON STOCK RESERVED FOR FUTURE ISSUANCE Common stock reserved for future issuance consists of the following:
5. RESEARCH AND DEVELOPMENT COLLABORATIONS AURORA BIOSCIENCES, INC. In July 1998, the Company entered into a Collaboration Agreement (the "Agreement") with Aurora Biosciences, Inc. ("Aurora"). During the two-year term of the Agreement, the companies agreed to enter into a screening collaboration in which Aurora will screen compounds for the Company utilizing its high-throughput screening technology with assays developed by the Company. Cytovia can access compounds currently in Aurora's compound libraries or can elect to use compounds purchased from other sources in completing the screens. During the term of the Agreement, Cytovia is to pay Aurora a total of $2,000,000 for screening services. As of December 31, 1999 and 1998, a total of $1,500,000 and $500,000, respectively, has been paid to Aurora and expensed under the terms of the Agreement. Aurora purchased 124,301 shares of Series B convertible preferred stock in connection with the Agreement. The Agreement also provides for the future payment of certain milestones and royalties to Aurora should any of the compounds discovered through the screening collaboration continue through the development process. 13 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 5. RESEARCH AND DEVELOPMENT COLLABORATIONS (CONTINUED) OTHER COLLABORATIVE RELATIONSHIPS In January 1998, the Company signed a License and Development Agreement (the "Agreement") with a collaborative partner. The Company licensed technology developed by the partner to measure the activity of caspases and other enzymes involved in apoptosis or programmed cell death. The Agreement gives the Company exclusive rights to commercially develop the technology for the commercial sector and allows for sublicensing of the technology by the Company. Any revenues derived from sublicensing or sales of products developed using the technology would result in royalty and milestone payments to the partner. In exchange for this license, the Company agreed to pay $2,000,000 over the life of the contract of which $1,000,000 related to 1999. Prior to the end of the Agreement, the Company determined that the collaborative partner was in breach of their responsibilities as outlined in the contract resulting in a notice of constructive breach being sent by the Company. Prior to that time, a total of $750,000 had been paid for the technology covered under the Agreement. An additional amount of $250,000 due under the Agreement in 1998 and $1,000,000 due in 1999 has not been paid. During 1999, the parties to the agreement entered into litigation to determine the responsibilities and obligations of each party. In January 2000, an out of court settlement was reached. The settlement calls for Cytovia to pay a total of $950,000 to the party in settlement of all claims. The amount is payable throughout the course of 2000 and has been accrued for as of December 31, 1999. 6. RELATED PARTY TRANSACTIONS From the Company's inception through October 31, 1998, Cytovia occupied a portion of CoCensys' facilities and utilized a portion of CoCensys' staff and infrastructure. During that period, a total of $1,125,316 was paid to CoCensys for reimbursement of costs incurred on Cytovia's behalf as well as payments for use of CoCensys' facilities, staff, and equipment. As of December 31, 1999 and 1998, no amounts were payable to CoCensys. 14 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 7. LEASE COMMITMENTS The Company leases its facilities and certain equipment under operating lease agreements that expire at various dates through 2004. The minimum annual rents are subject to specified annual rental increases. Rent expense was $521,641 and $188,658 for the years ended December 31, 1999 and 1998, respectively. Rent expense for the period from January 9, 1998 (inception) through December 31, 1999 was $710,299. The Company leases certain equipment under capital lease obligations. Included in property and equipment are capital leases with an original purchase price of $1,320,534 and $781,830 as of December 31, 1999 and 1998, respectively. Annual future minimum obligations for operating and capital leases are as follows:
As of December 31, 1999, the Company has approximately $264,495 of available funding under equipment lease lines. 15 Cytovia, Inc. (a development stage company) Notes to Financial Statements (continued) 8. INCOME TAXES At December 31, 1999, the Company has federal and state tax net operating loss carryforwards of approximately $9,855,000 and $2,470,000, respectively. The federal and state tax loss carryforwards will begin to expire in 2006, unless previously utilized. The Company also has federal and state research and development tax credit carryforwards of approximately $499,000 and $274,000, respectively, which will begin to expire in 2018, unless previously utilized. Pursuant to Internal Revenue Code Sections 382 and 383, use of the Company's net operating loss and credit carryforwards may be limited if a cumulative change in ownership of more than 50% occurs within a three-year period. However, the Company does not believe such limitations will have a material impact upon the utilization of these carryforwards. Significant components of the Company's deferred tax assets as of December 31, 1999 are shown below. A valuation allowance of $5,149,000 has been recognized as realization of such assets is uncertain.
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