LEAP THERAPEUTICS, INC. Contracts & Agreements

Form of Securities Purchase Agreement by and among the Company and the purchasers named therein (Filed With SEC on April 11, 2024)

Form of Pre-Funded Warrant (Filed With SEC on April 11, 2024)

Amendment No. 1 to Leap Therapeutics, Inc. 2022 Equity Incentive Plan (Filed With SEC on March 18, 2024)

Form of Warrant, dated May 6, 2020, by and among the Flame Biosciences, Inc. and the Warrantholders (Filed With SEC on May 15, 2023)

Strategic Partnership and License Agreement, dated August 13, 2021, by and between NovaRock Biotherapeutics Ltd. and Flame Biosciences, Inc (Filed With SEC on May 15, 2023)

Collaboration Agreement, dated August 10, 2020, by and between Adimab, LLC and Flame Biosciences, Inc (Filed With SEC on May 15, 2023)

Second Amendment to Executive Employment Agreement, dated April 3, 2023, by and between the Company and John Mark OMahony (Filed With SEC on May 15, 2023)

Executive Employment Agreement, by and between the Company and Jason S. Baum (Filed With SEC on May 15, 2023)

First Amendment to Executive Employment Agreement, dated April 3, 2023, by and between the Company and Jason S. Baum (Filed With SEC on May 15, 2023)

Second Amendment to Executive Employment Agreement, by and between the Company and Dr. Cynthia Sirard, dated as of April 3, 2023 (Filed With SEC on April 7, 2023)

Continuing Clinical Collaboration Letter Agreement (Filed With SEC on March 16, 2023)

Registration Rights Agreement, dated January 17, 2023, by and among the Company and the Holders (Filed With SEC on January 23, 2023)

Agreement and Plan of Merger, dated January 17, 2023, by and among Leap Therapeutics, Inc., Fire Merger Sub, Inc., Flame Biosciences LLC, Flame Biosciences, Inc., and the... (Filed With SEC on January 23, 2023)

Support Agreement by and between Leap Therapeutics, Inc. and HealthCare Ventures IX L.P., dated January 17, 2023 (Filed With SEC on January 23, 2023)

Support Agreement by and between Leap Therapeutics, Inc. and HealthCare Ventures VIII Liquidating Trust, dated January 17, 2023 (Filed With SEC on January 23, 2023)

Third Amendment to Lease by and between Bullfinch Square Limited Partnership and Leap Therapeutics, Inc., dated as of May 16, 2022 (Filed With SEC on August 12, 2022)

Second Amendment to Lease by and between Bulfinch Square Limited Partnership and Leap Therapeutics, Inc. dated as of October 1, 2021 (Filed With SEC on March 11, 2022)

First Amendment to Lease by and between Bullfinch Square Limited Partnership and Leap Therapeutics, Inc., dated as of August 17, 2021 (Filed With SEC on November 12, 2021)

Underwriting Agreement, dated September 22, 2021, by and among Leap Therapeutics, Inc. and Piper Sandler & Co. and Raymond James & Associates, Inc., as representatives of the... (Filed With SEC on September 22, 2021)

Form of Pre-Funded Warrant to Purchase Common Stock (Filed With SEC on September 22, 2021)

First Amendment, dated as of April 15, 2021, to Employment Agreement, by and between the Company and Cynthia Sirard, dated as of April 10, 2020 (Filed With SEC on August 13, 2021)

First Amendment, dated as of April 20, 2021, to Employment Agreement, by and between the Company and John Mark OMahony, dated as of April 10, 2020 (Filed With SEC on August 13, 2021)

Employment Agreement, by and between the Company and Cynthia Sirard, dated as of April 10, 2020 (Filed With SEC on March 12, 2021)

Employment Agreement, by and between the Company and John Mark O Mahony, dated as of April 10, 2020 (Filed With SEC on March 12, 2021)

Employment Agreement, by and between the Company and Christine Granfield, dated as of August 16, 2020 (Filed With SEC on November 12, 2020)

Underwriting Agreement, dated June 18, 2020, by and among Leap Therapeutics, Inc. and Piper Sandler & Co. and Raymond James & Associates, Inc., as representatives of the... (Filed With SEC on June 18, 2020)

Form of Pre-Funded Warrant to Purchase Common Stock (Filed With SEC on June 18, 2020)

Exclusive Option and License Agreement dated as of January 3, 2020, by and between the Company and BeiGene, Ltd (Filed With SEC on May 14, 2020)

Employment Agreement, by and between the Company and Douglas E. Onsi, dated as of April 10, 2020 (Filed With SEC on April 15, 2020)

Description of the Registrant's Securities registered pursuant to Section 12 of the Securities Exchange Act of 1934 (Filed With SEC on March 16, 2020)

Form of Series B Coverage Warrant (Filed With SEC on January 7, 2020)

Form of Series A Coverage Warrant (Filed With SEC on January 7, 2020)

Form of Pre-Funded Warrant (Filed With SEC on January 7, 2020)

Registration Rights Agreement dated as of July 10, 2019, by and between the Company and Lincoln Park Capital Fund, LLC (Filed With SEC on July 11, 2019)

Purchase Agreement dated as of July 10, 2019, by and between the Company and Lincoln Park Capital Fund, LLC (Filed With SEC on July 11, 2019)

Purchase Agreement dated as of July 11, 2019, by and between the Company and Lincoln Park Capital Fund, LLC (Filed With SEC on July 11, 2019)

Form of Warrant (Filed With SEC on February 1, 2019)

Underwriting Agreement, dated February 1, 2019, by and among Leap Therapeutics, Inc., Raymond James & Associates, Inc. and Ladenburg Thalmann & Co. Inc., as representatives of the... (Filed With SEC on February 1, 2019)

Lease, dated November 13, 2018, by and between the Company and Bulfinch Square Limited Partnership (Filed With SEC on November 19, 2018)

Distribution Agreement dated September 7, 2018 (Filed With SEC on September 7, 2018)

Underwriting Agreement, dated March 23, 2018, by and among Leap Therapeutics, Inc. and Raymond James & Associates, Inc. and Ladenburg Thalmann & Co. Inc., as representatives of... (Filed With SEC on March 23, 2018)

Voting Agreement, dated as of November 14, 2017, by and among Leap Therapeutics, Inc., HealthCare Ventures VIII, L.P., HealthCare Ventures IX, L.P. and HealthCare Ventures... (Filed With SEC on November 17, 2017)

Placement Agency Agreement, dated as of November 14, 2017, by and between Leap Therapeutics, Inc., Raymond James & Associates, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on November 17, 2017)

Form of Purchase Agreement, dated as of November 14, 2017, by and among Leap Therapeutics, Inc. and the purchasers identified on the schedule thereto (Filed With SEC on November 17, 2017)

Form of Warrant, dated as of November 14, 2017 by and among Leap Therapeutics, Inc. and the purchasers identified on the schedule thereto (Filed With SEC on November 17, 2017)

AMENDMENT NO. 2 TO WARRANT (Filed With SEC on March 31, 2017)

LEAP THERAPEUTICS, INC. NOTICE OF GRANT OF STOCK OPTION (Filed With SEC on March 31, 2017)

LEASE BY AND BETWEEN BULFINCH SQUARE LIMITED PARTNERSHIP LANDLORD AND HEALTHCARE VENTURES LLC TENANT 43-47 Thorndike Street Cambridge, Massachusetts (Filed With SEC on March 31, 2017)

AMENDMENT TO LEASE (Filed With SEC on March 31, 2017)

FIRST AMENDMENT TO LEASE (Filed With SEC on March 31, 2017)

CONSENT TO ASSIGNMENT AND ASSUMPTION OF LEASE (Filed With SEC on March 31, 2017)

LETTER AGREEMENT (Filed With SEC on January 26, 2017)

SUBSCRIPTION AGREEMENT (Filed With SEC on January 26, 2017)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on January 26, 2017)

ROYALTY AGREEMENT BETWEEN LEAP THERAPEUTICS, INC. AND LEAP SHAREHOLDER ROYALTY VEHICLE, LLC EFFECTIVE AS OF JANUARY 23, 2017 (Filed With SEC on January 26, 2017)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on September 26, 2016)

ROYALTY AGREEMENT BETWEEN LEAP THERAPEUTICS, INC. AND [LEAP SHAREHOLDER ROYALTY VEHICLE, LLC] EFFECTIVE AS OF [], 2016 (Filed With SEC on September 26, 2016)

LICENCE AGREEMENT between LONZA SALES AG and HEALTHCARE PHARMACEUTICALS, INC. (Filed With SEC on September 26, 2016)

LICENSE AGREEMENT BETWEEN ELI LILLY AND COMPANY AND DEKKUN CORPORATION EFFECTIVE AS OF JANUARY 3, 2011 (Filed With SEC on September 26, 2016)

LEAP THERAPEUTICS, INC. 2016 EQUITY INCENTIVE PLAN (Filed With SEC on September 26, 2016)

LEAP THERAPEUTICS, INC. AMENDED AND RESTATED 2012 EQUITY INCENTIVE PLAN (Filed With SEC on September 26, 2016)

AMENDMENT NO. 2 TO WARRANT (Filed With SEC on September 26, 2016)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on September 26, 2016)

AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (Filed With SEC on September 26, 2016)

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LEAP THERAPEUTICS, INC. Contracts & Agreements