LA JOLLA PHARMACEUTICAL CO Contracts & Agreements

Agreement and Plan of Merger by and among the Parent, the Purchaser and the Company, dated as of July 10, 2022 (Filed With SEC on July 11, 2022)

Support Agreement, dated as of July 10, 2022, by and among the Parent, the Purchaser and the stockholders named therein (Filed With SEC on July 11, 2022)

Description of Securities (Filed With SEC on March 9, 2022)

Amended Employment Offer Letter by and between La Jolla Pharmaceutical Company and Larry Edwards (Filed With SEC on November 4, 2021)

PAION AG Exclusive Licensing Agreement, dated January 12, 2021 (Filed With SEC on March 8, 2021)

License Agreement, dated as of August 3, 2006, by and between the Registrant and the President and Fellows of Harvard College, as amended (Filed With SEC on March 8, 2021)

Amendment, dated as of December 5, 2017, by and between the Registrant and the President and Fellows of Harvard College, as amended (Filed With SEC on March 8, 2021)

Employment Offer Letter by and between La Jolla Pharmaceutical Company and Larry Edwards dated as of July 28, 2020 (Filed With SEC on November 9, 2020)

Contingent Value Rights Agreement, dated as of July 17, 2020, between La Jolla Pharmaceutical Company and American Stock Transfer & Trust Company, LLC, as Rights Agent (Filed With SEC on July 29, 2020)

Agreement and Plan of Merger by and among the La Jolla, Merger Sub and Tetraphase, dated June 24, 2020 (Filed With SEC on June 24, 2020)

Form of Contingent Value Rights Agreement, by and between La Jolla and the Rights Agent (Filed With SEC on June 24, 2020)

Form of Support Agreement, dated June 24, 2020, by and among La Jolla, Merger Sub and the stockholder named therein (Filed With SEC on June 24, 2020)

Form of Exchange Agreement, dated June 24, 2020, by and among La Jolla, Merger Sub and the holder named therein (Filed With SEC on June 24, 2020)

Description of Securities (Filed With SEC on March 2, 2020)

Form of Indemnification Agreement (Filed With SEC on March 2, 2020)

Employment Offer Letter by and between La Jolla Pharmaceutical Company and Darryl Wellinghoff dated as of February 25, 2019 (Filed With SEC on March 2, 2020)

Revenue Interest Agreement, dated May 10, 2018, among La Jolla Pharma, LLC, HealthCare Royalty Partners III, L.P., HCRP Overflow Fund, L.P. and HCR Molag Fund, L.P (Filed With SEC on May 14, 2018)

Underwriting Agreement, dated March 14, 2018, between La Jolla Pharmaceutical Company and Cowen and Company, LLC (Filed With SEC on March 19, 2018)

Amended and Restated Patent License Agreement by and between La Jolla Pharmaceutical Company and the George Washington University dated March 1, 2016 (Filed With SEC on February 22, 2018)

3,731,344 Shares LaJolla Pharmaceutical Company UNDERWRITING AGREEMENT (Filed With SEC on March 24, 2017)

EXHIBIT A RELEASE AND WAIVER OF CLAIMS TO BE SIGNED AT TIME OF TERMINATION WITHOUT CAUSE OR RESIGNATION FOR GOOD REASON (Filed With SEC on February 25, 2016)

2,550,000 Shares LaJolla Pharmaceutical Company UNDERWRITING AGREEMENT (Filed With SEC on September 15, 2015)

Dated:March 16, 2015/s/ Dennis M. MulroyDennis M. Mulroy (Filed With SEC on April 10, 2015)

4,800,000 Shares La Jolla Pharmaceutical Company UNDERWRITING AGREEMENT (Filed With SEC on July 25, 2014)

CERTIFICATE OF DETERMINATION of SERIES FCONVERTIBLE PREFERRED STOCK of LA JOLLA PHARMACEUTICAL COMPANY Pursuant to Section 401 of the California General Corporation Law (Filed With SEC on September 25, 2013)

AMENDED AND RESTATED ARTICLES OF INCORPORATION OF LA JOLLAPHARMACEUTICAL COMPANY Pursuant to Section 910 of the California General Corporation Law (Filed With SEC on September 25, 2013)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on September 25, 2013)

CONSENT AND WAIVER AGREEMENT (Filed With SEC on September 25, 2013)

EXCHANGE AGREEMENT (Filed With SEC on September 25, 2013)

LA JOLLA PHARMACEUTICAL COMPANY RESTRICTED STOCK AGREEMENT (Filed With SEC on September 25, 2013)

LA JOLLA PHARMACEUTICAL COMPANY 2013 EQUITY INCENTIVE PLAN (Filed With SEC on September 25, 2013)

CONSENT, WAIVER AND AMENDMENT AGREEMENT (Filed With SEC on April 1, 2013)

AGREEMENT AND PLAN OF MERGER OF LA JOLLA PHARMACEUTICAL COMPANY, ADELAWARE CORPORATION AND LJPC MERGER SUB, INC., A CALIFORNIA CORPORATION (Filed With SEC on June 20, 2012)

APPENDIX C 2010 Equity Incentive Plan LA JOLLA PHARMACEUTICAL COMPANY 2010 EQUITY INCENTIVE PLAN ARTICLE I GENERAL PROVISIONS (Filed With SEC on March 30, 2012)

ASSET PURCHASE AGREEMENT (Filed With SEC on January 20, 2012)

CONSENT AND AMENDMENT AGREEMENT (Filed With SEC on January 20, 2012)

CONFIDENTIAL SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS (Filed With SEC on January 20, 2012)

LA JOLLA PHARMACEUTICAL COMPANY (Filed With SEC on January 20, 2012)

SECOND AMENDMENT AGREEMENT (Filed With SEC on August 25, 2011)

AMENDMENT AGREEMENT (Filed With SEC on July 5, 2011)

ASSET PURCHASE AGREEMENT (Filed With SEC on April 5, 2011)

CONSENT AND AMENDMENT AGREEMENT (Filed With SEC on April 5, 2011)

Current assets (Filed With SEC on November 12, 2010)

SECURITIES PURCHASE AGREEMENT Dated as of May 24, 2010 by and among LA JOLLA PHARMACEUTICAL COMPANY and THE PURCHASERS LISTED ON EXHIBIT A SECURITIES PURCHASE AGREEMENT (Filed With SEC on May 28, 2010)

FORM OF SERIES C-2 PREFERRED STOCK PURCHASE WARRANT LA JOLLA PHARMACEUTICAL COMPANY (Filed With SEC on May 28, 2010)

FORM OF SERIES D-1 PREFERRED STOCK PURCHASE WARRANT LA JOLLA PHARMACEUTICAL COMPANY (Filed With SEC on May 28, 2010)

FORM OF SERIES D-2 PREFERRED STOCK PURCHASE WARRANT LA JOLLA PHARMACEUTICAL COMPANY (Filed With SEC on May 28, 2010)

CHIEF EXECUTIVE OFFICER EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2010)

CONFIDENTIAL RETENTION AGREEMENT (Filed With SEC on May 28, 2010)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on May 28, 2010)

CONFIDENTIAL RETENTION AGREEMENT (Filed With SEC on May 28, 2010)

VIA FACSIMILE AND EMAIL March 3, 2010 Adamis Pharmaceutical Corporation 2658 Del Mar Heights Road, #555 Del Mar, California 92014 Attention: President Re: Termination of Merger... (Filed With SEC on March 5, 2010)

AGREEMENT AND PLAN OF REORGANIZATION among LA JOLLA PHARMACEUTICAL COMPANY a Delaware corporation, JEWEL MERGER SUB, INC., a Delaware corporation and ADAMIS PHARMACEUTICALS... (Filed With SEC on December 7, 2009)

RETENTION AND SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS (Filed With SEC on December 7, 2009)

VOTING AGREEMENT (Filed With SEC on December 7, 2009)

Current assets (Filed With SEC on May 18, 2009)

Sell or out-license our remaining assets, including our SSAO compounds, although we do not expect to receive any substantive value for them (Filed With SEC on March 31, 2009)

AMENDMENT NO. 1 TO AMENDED AND RESTATED RIGHTS AGREEMENT (Filed With SEC on January 26, 2009)

Entry into a Material Definitive Agreement (Filed With SEC on May 14, 2008)

Entry into a Material Definitive Agreement (Filed With SEC on May 7, 2008)

PROMISSORY NOTE (Filed With SEC on March 17, 2008)

* * * (Filed With SEC on March 4, 2008)

Current assets (Filed With SEC on August 7, 2007)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on May 10, 2007)

Focus on higher doses all new patients entering the study will be randomized in equal numbers to receive weekly doses of either 300 mg or 900 mg of Riquent or placebo, with no... (Filed With SEC on March 16, 2007)

Current assets (Filed With SEC on August 8, 2006)

/s/ Michael Tansey 7/14/06 Michael Tansey, BSc, MB ChB, MD, FFPM Date (Filed With SEC on July 18, 2006)

EXHIBIT 10.1 LA JOLLA PHARMACEUTICAL COMPANY 1995 EMPLOYEE STOCK PURCHASE PLAN (Filed With SEC on May 22, 2006)

CHIEF EXECUTIVE OFFICER EMPLOYMENT AGREEMENT (Filed With SEC on March 20, 2006)

SEPARATION AGREEMENT (Filed With SEC on March 20, 2006)

LA JOLLA PHARMACEUTICAL COMPANY 2004 EQUITY INCENTIVE PLAN ARTICLE I GENERAL PROVISIONS (Filed With SEC on March 13, 2006)

AMENDMENT NO. 3 TO RIGHTS AGREEMENT (Filed With SEC on March 1, 2006)

AMENDED AND RESTATED EMPLOYMENT AGREEMENT (Filed With SEC on March 1, 2006)

AMENDMENT NO. 2 TO RIGHTS AGREEMENT (Filed With SEC on December 16, 2005)

LA JOLLA PHARMACEUTICAL COMPANY 2004 EQUITY INCENTIVE PLAN ARTICLE I GENERAL PROVISIONS (Filed With SEC on December 16, 2005)

Current assets (Filed With SEC on November 7, 2005)

Current assets (Filed With SEC on August 9, 2005)

EXHIBIT 10.1 LA JOLLA PHARMACEUTICAL COMPANY 2004 EQUITY INCENTIVE PLAN ARTICLE I GENERAL PROVISIONS (Filed With SEC on May 20, 2005)

EXHIBIT 10.2 LA JOLLA PHARMACEUTICAL COMPANY 1995 EMPLOYEE STOCK PURCHASE PLAN (Filed With SEC on May 20, 2005)

Current assets (Filed With SEC on May 9, 2005)

Entry Into A Material Definitive Agreement (Filed With SEC on January 28, 2005)

Current assets (Filed With SEC on November 5, 2004)

Current assets (Filed With SEC on August 6, 2004)

Current assets (Filed With SEC on May 7, 2004)

Exhibit No (Filed With SEC on February 20, 2004)

PART I. FINANCIAL INFORMATION (Filed With SEC on November 10, 2003)

Exhibit No (Filed With SEC on August 12, 2003)

PART I. FINANCIAL INFORMATION (Filed With SEC on August 5, 2003)

PART I. FINANCIAL INFORMATION (Filed With SEC on May 13, 2003)

PART I. FINANCIAL INFORMATION (Filed With SEC on November 7, 2002)

PART I. FINANCIAL INFORMATION (Filed With SEC on August 14, 2002)

PART I. FINANCIAL INFORMATION (Filed With SEC on May 14, 2002)

Form of Stock Purchase Agreement between the Company and Purchasers (Filed With SEC on January 16, 2002)

PART I. FINANCIAL INFORMATION (Filed With SEC on August 14, 2001)