Krystal Biotech, Inc. Contracts & Agreements

Securities Purchase Agreement, by and among Krystal Biotech, Inc. and the institutional investors listed on the signature pages thereto, dated as of May 21, 2023 (Filed With SEC on May 22, 2023)

Registration Rights Agreement, by and among Krystal Biotech, Inc. and the institutional investors listed on the signature pages thereto, dated as of May 21, 2023 (Filed With SEC on May 22, 2023)

Form of Time-Based Restricted Stock Unit Award Agreement under the 2017 IPO Stock Incentive Plan (Filed With SEC on May 8, 2023)

Form of Performance-Based Restricted Stock Unit Award Agreement under the 2017 IPO Stock Incentive Plan (Filed With SEC on May 8, 2023)

Sales Agreement, dated May 8, 2023, by and between Krystal Biotech, Inc. and Cowen and Company, LLC (Filed With SEC on May 8, 2023)

Description of Common Stock (Filed With SEC on February 27, 2023)

Form of Krystal Biotech, Inc. 2017 IPO Stock Incentive Plan Notice of (Filed With SEC on February 27, 2023)

Executive Employment Agreement, effective May 3, 20201 by and between Krystal Biotech, Inc. and Andy (Filed With SEC on February 28, 2022)

Executive Employment Agreement, effective January 18, 2022, by and between Krystal Biotech, Inc. and Jing Marantz (Filed With SEC on February 28, 2022)

Sixth amendment to Lease Agreement and first amendment to storage space agreement, dated as of January 13, 2021, by and between Wharton Lender Associates, L.P. and Krystal... (Filed With SEC on February 28, 2022)

Seventh amendment to Lease Agreement, dated as of May 11, 2021, by and between Wharton Lender Associates, L.P. and Krystal Biotech, Inc (Filed With SEC on February 28, 2022)

Eighth amendment to Lease Agreement, dated as of July 21, 2021, by and between Wharton Lender Associates, L.P. and Krystal Biotech, Inc (Filed With SEC on February 28, 2022)

Ninth amendment to Lease Agreement, dated as of January 4, 2022, by and between Wharton Lender Associates, L.P. and Krystal Biotech, Inc (Filed With SEC on February 28, 2022)

Underwriting Agreement, dated November 30, 2021, by and among the Company and Goldman Sachs & Co. LLC, BofA Securities, Inc., Cowen and Company, LLC and William Blair & Company,... (Filed With SEC on December 3, 2021)

Guaranteed Maximum Price Amendment dated September 13, 2021 (Filed With SEC on September 16, 2021)

Standard Form of Contract for Construction and the corresponding General Conditions of the Contract for Construction (Filed With SEC on August 9, 2021)

Purchase and Sale Agreement, dated January 29, 2021, by and between Krystal Biotech, Inc. and Northfield I, LLC (incorporated by reference to Exhibit 10.1 to the Companys Current... (Filed With SEC on May 10, 2021)

Description of Common Stock (incorporated by reference to Exhibit 4.3 to the Company's Annual Report on Form 10-K (File No. 001-38210), as filed with the SEC on March 10, 2020) (Filed With SEC on March 1, 2021)

Executive Employment Agreement, effective January 20, 2020, by and between Krystal Biotech, Inc. and Kathryn A. Romano (Filed With SEC on March 1, 2021)

Third amendment to Lease Agreement, dated as of May 31, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Fourth amendment to Lease Agreement, dated as of October 22, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Fifth amendment to Lease Agreement, dated as of December 10, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Lease Agreement, dated as of December 26, 2019, by and between Northfield I, LLC and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

First Amendment to Lease Agreement, dated as of January 17, 2020, between Northfield I, LLC and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Second Amendment to Lease Agreement, dated as of August 12, 2020, between Northfield I, LLC and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Third Amendment to Lease Agreement, dated as of December 14, 2020, between Northfield I, LLC and Krystal Biotech, Inc (Filed With SEC on March 1, 2021)

Underwriting Agreement, dated February 2, 2021, by and among the Company and Goldman Sachs & Co. LLC, Cowen and Company, LLC and Evercore Group L.L.C. as representatives of the... (Filed With SEC on February 5, 2021)

Purchase and Sale Agreement, dated January 29, 2021, by and between Krystal Biotech, Inc. and Northfield I, LLC (Filed With SEC on February 2, 2021)

Sales Agreement, dated December 31, 2020, by and between Krystal Biotech, Inc. and Cowen and Company, LLC (Filed With SEC on December 31, 2020)

Underwriting Agreement, dated May 18, 2020, by and among the Company and Cowen and Company, LLC and Evercore Group L.L.C. as representatives of the several Underwriters named... (Filed With SEC on May 21, 2020)

Executive Employment Agreement, effective January 20, 2020, by and between Krystal Biotech, Inc. and Kathryn A. Romano (Filed With SEC on May 4, 2020)

Executive Employment Agreement, effective January 20, 2020, by and between Krystal Biotech, Inc. and Jennifer Chien (Filed With SEC on May 4, 2020)

Description of Common Stock (Filed With SEC on March 10, 2020)

Third amendment to Lease Agreement, dated as of May 31, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 10, 2020)

Fourth amendment to Lease Agreement, dated as of October 22, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 10, 2020)

Fifth amendment to Lease Agreement, dated as of December 10, 2018, by and between Wharton Lender Associate, L.P. and Krystal Biotech, Inc (Filed With SEC on March 10, 2020)

Lease Agreement, dated as of December 26, 2019, by and between Northfield I, LLC and Krystal Biotech, Inc (Filed With SEC on March 10, 2020)

Underwriting Agreement, dated June 24, 2019, by and among the Company and Goldman Sachs & Co. LLC and Cowen and Company, LLC as representatives of the several Underwriters named... (Filed With SEC on June 27, 2019)

Sales Agreement, dated as of March 12, 2019, between Krystal Biotech, Inc. and Cowen and Company, LLC (Filed With SEC on March 13, 2019)

Underwriting Agreement, dated October 18, 2018, by and among the Company and Cowen and Company, LLC, William Blair & Company, L.L.C. and Cantor Fitzgerald & Co. as representatives... (Filed With SEC on October 19, 2018)

Offer of employment to Antony Riley (Filed With SEC on March 12, 2018)

Form of Underwriting Agreement (Filed With SEC on September 14, 2017)

Form of Common Stock Certificate (Filed With SEC on September 14, 2017)

Form of Indemnification Agreement by and between Krystal Biotech, Inc. and each of its directors and officers listed on Schedule A thereto (Filed With SEC on September 14, 2017)

Krystal Biotech, LLC 2016 Equity Incentive Plan (Filed With SEC on September 14, 2017)

Krystal Biotech, Inc. 2017 Stock Incentive Plan (Filed With SEC on September 14, 2017)

Krystal Biotech, Inc. 2017 IPO Stock Incentive Plan (Filed With SEC on September 14, 2017)

Form of Krystal Biotech, Inc. 2017 Stock Incentive Plan Notice of Stock Option Award (Filed With SEC on September 14, 2017)

Form of Krystal Biotech, Inc. 2017 IPO Stock Incentive Plan Notice of Stock Option Award (Filed With SEC on September 14, 2017)

Executive Employment Agreement, effective July 1, 2017, by and between Krystal Biotech, Inc. and Krish S. Krishnan (Filed With SEC on September 7, 2017)

Executive Employment Agreement, effective May 1, 2017, by and between Krystal Biotech, Inc. and Suma M. Krishnan (Filed With SEC on September 7, 2017)

Executive Employment Agreement, effective May 1, 2017, by and between Krystal Biotech, Inc. and Pooja Agarwal (Filed With SEC on September 7, 2017)

Lease Agreement, dated as of May 26, 2016, by and between Wharton Lender Associates, L.P. and Krystal Biotech, LLC (Filed With SEC on September 7, 2017)

Second Amendment to Lease Agreement, dated as of February 27, 2017, by and between Wharton Lender Associates, L.P. and Krystal Biotech, LLC (Filed With SEC on September 7, 2017)

INVESTORS RIGHTS AGREEMENT (Filed With SEC on August 21, 2017)

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Krystal Biotech, Inc. Contracts & Agreements