KERYX BIOPHARMACEUTICALS INC Contracts & Agreements

First Supplemental Indenture dated November 8, 2018, by and between Keryx Biopharmaceuticals, Inc. and The Bank of New York Mellon Trust Company, N.A. to the Indenture dated as of... (Filed With SEC on November 8, 2018)

Amendment to Employment Agreement with Jodie Morrison effective as of October 31, 2018 (Filed With SEC on November 8, 2018)

First Amendment to Agreement and Plan of Merger dated October 1, 2018, by and among Akebia Therapeutics, Inc., Alpha Therapeutics Merger Sub Inc. and Keryx Biopharmaceuticals, Inc (Filed With SEC on October 1, 2018)

Amendment No. 1 to the Product Manufacture and Supply and Facility Construction Agreement, dated May 5, 2018, by and between Keryx Biopharmaceuticals, Inc. and BioVectra Inc (Filed With SEC on August 9, 2018)

Retention Bonus Award Agreement with Scott A. Holmes dated May 1, 2018 (Filed With SEC on August 9, 2018)

Retention Bonus Award Agreement with John F. Neylan dated May 1, 2018 (Filed With SEC on August 9, 2018)

Retention Bonus Award Agreement with Christine Carberry dated May 1, 2018 (Filed With SEC on August 9, 2018)

Loan and Security Agreement dated July 18, 2018, between Keryx Biopharmaceuticals, Inc. and Silicon Valley Bank (Filed With SEC on July 20, 2018)

Agreement and Plan of Merger, dated as of June 28, 2018, by and among Akebia Therapeutics, Inc., Alpha Therapeutics Merger Sub Inc. and Keryx Biopharmaceuticals, Inc (Filed With SEC on June 28, 2018)

Notes Conversion Agreement, dated as of June 28, 2018, by and among Keryx Biopharmaceuticals, Inc., Baupost Group Securities, L.L.C. and, with respect to certain sections only,... (Filed With SEC on June 28, 2018)

Separation Agreement between Keryx Biopharmaceuticals, Inc. and Mr. Madison, dated June 14, 2018 (Filed With SEC on June 15, 2018)

Amended and Restated License Agreement by and between Panion & BF Biotech, Inc. and Keryx Biopharmaceuticals, Inc. dated March 17, 2008 (Filed With SEC on May 10, 2018)

Employment Agreement with Jodie Morrison dated May 10, 2018 (Filed With SEC on May 10, 2018)

Notes Exchange Agreement dated as of May 8, 2018, between Keryx Biopharmaceuticals, Inc. and Baupost Group Securities, L.L.C (Filed With SEC on May 10, 2018)

Indenture dated as of May 9, 2018, between Keryx Biopharmaceuticals, Inc. and The Bank of New York Mellon Trust Company, N.A (Filed With SEC on May 10, 2018)

Registration Rights Agreement dated as of May 9, 2018, between Keryx Biopharmaceuticals, Inc. and Baupost Group Securities, L.L.C (Filed With SEC on May 10, 2018)

Product Manufacture and Supply and Facility Construction Agreement, dated December 11, 2017, by and between Keryx Biopharmaceuticals, Inc. and BioVectra Inc (Filed With SEC on February 21, 2018)

Master Manufacturing Services and Supply Agreement, dated December 20, 2017, by and between Keryx Biopharmaceuticals, Inc. and Siegfried Evionnaz SA (Filed With SEC on February 21, 2018)

Employment Agreement with Gregory P. Madison dated March 10, 2015 (Filed With SEC on February 21, 2018)

Amended and Restated Sub-License Agreement, dated June 8, 2009, as amended by the First Amendment thereto, dated June 12, 2013, by and between Keryx Biopharmaceuticals, Inc.,... (Filed With SEC on November 7, 2017)

Product Agreement, dated August 29, 2017, by and between Keryx Biopharmaceuticals, Inc. and Patheon Inc. (an affiliate of Patheon Manufacturing Services LLC) related to the Master... (Filed With SEC on November 7, 2017)

FIRSTSUPPLEMENTAL INDENTURE (Filed With SEC on April 10, 2017)

Confidential Materials Omitted, Designated Herein as [***], and Filed Separately with the Securities and Exchange Commission Master Manufacturing Services Agreement September 27,... (Filed With SEC on March 1, 2017)

AMENDMENT TWO TO EMPLOYMENT AGREEMENT (Filed With SEC on March 1, 2017)

ONE MARINA PARK DRIVE OFFICE LEASE (Filed With SEC on March 1, 2017)

EMPLOYMENT AGREEMENT BETWEEN CHRISTINE A.CARBERRY AND KERYX BIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT (Filed With SEC on January 9, 2017)

INDEMNIFICATION AGREEMENT (Filed With SEC on November 9, 2016)

KERYX BIOPHARMACEUTICALS, INC. AMENDED AND RESTATED 2013 INCENTIVE PLAN KERYX BIOPHARMACEUTICALS, INC. AMENDED AND RESTATED 2013 INCENTIVE PLAN (Filed With SEC on May 27, 2016)

KERYX BIOPHARMACEUTICALS, INC. FOURTH AMENDED AND RESTATED DIRECTORS EQUITY COMPENSATION PLAN ARTICLE 1 PURPOSE (Filed With SEC on May 27, 2016)

AMENDMENT ONE TO EMPLOYMENT AGREEMENT (Filed With SEC on October 29, 2015)

NOTESPURCHASE AGREEMENT (Filed With SEC on October 19, 2015)

KERYX BIOPHARMACEUTICALS, INC. ZERO COUPON CONVERTIBLE SENIOR NOTES DUE 2020 INDENTURE DATED AS OF OCTOBER 15, 2015 THE BANK OF NEWYORK MELLON TRUST COMPANY, N.A., AS TRUSTEE... (Filed With SEC on October 19, 2015)

REGISTRATIONRIGHTS AGREEMENT BY AND AMONG KERYX BIOPHARMACEUTICALS, INC. AND BAUPOST GROUPSECURITIES, L.L.C. DATED AS OF OCTOBER 15, 2015 TABLE OF CONTENTS (Filed With SEC on October 19, 2015)

EMPLOYMENT AGREEMENT BETWEEN SCOTT HOLMES AND KERYXBIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT (Filed With SEC on July 27, 2015)

Keryx Biopharmaceuticals Appoints Scott A. Holmes as Chief Financial Officer (Filed With SEC on July 27, 2015)

EMPLOYMENT AGREEMENT BETWEEN GREGORY P.MADISON AND KERYX BIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT TABLE OF CONTENTS (Filed With SEC on May 4, 2015)

EMPLOYMENT AGREEMENT BETWEEN BRIAN R. ADAMS AND KERYXBIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT (Filed With SEC on May 4, 2015)

EMPLOYMENT AGREEMENT BETWEEN JOHN F. NEYLANM.D. AND KERYX BIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT (Filed With SEC on May 4, 2015)

THIRD AMENDMENT to the EMPLOYMENT AGREEMENT Between RON BENTSUR and KERYX BIOPHARMACEUTICALS, INC. (Filed With SEC on May 4, 2015)

EMPLOYMENT AGREEMENT BETWEEN JAMES F.OLIVIERO AND KERYX BIOPHARMACEUTICALS, INC. (Filed With SEC on February 27, 2015)

KeryxBiopharmaceuticals, Inc. 9,166,667 Shares Common Stock ($0.001par value) Underwriting Agreement (Filed With SEC on January 27, 2015)

Manufacturing Services Agreement January 17, 2014 Table of Contents (Filed With SEC on November 6, 2014)

FIRST ADDENDUM TO MANUFACTURING SERVICES AGREEMENT (Filed With SEC on November 6, 2014)

KERYX BIOPHARMACEUTICALS, INC. THIRD AMENDED AND RESTATED DIRECTORS EQUITY COMPENSATION PLAN KERYX BIOPHARMACEUTICALS, INC. THIRD AMENDED AND RESTATED DIRECTORS EQUITY... (Filed With SEC on August 7, 2014)

EMPLOYMENT AGREEMENT BETWEEN GREGORY P.MADISON AND KERYX BIOPHARMACEUTICALS, INC. EMPLOYMENT AGREEMENT (Filed With SEC on February 10, 2014)

KeryxBiopharmaceuticals, Inc. 6,900,000 Shares Common Stock ($0.001par value) Underwriting Agreement (Filed With SEC on January 28, 2014)

SECOND AMENDMENT to the EMPLOYMENT AGREEMENT between RON BENTSUR and KERYX BIOPHARMACEUTICALS, INC. (Filed With SEC on June 13, 2013)

SECOND AMENDMENT TO CHANGE IN CONTROL AGREEMENT (Filed With SEC on June 13, 2013)

Keryx Biopharmaceuticals, Inc. 8,234,000 Shares Common Stock ($0.001 par value) Underwriting Agreement (Filed With SEC on February 5, 2013)

LICENSE TERMINATION AND TECHNOLOGY TRANSFER AGREEMENT (Filed With SEC on May 9, 2012)

CHANGE IN CONTROL AGREEMENT (Filed With SEC on March 2, 2012)

FIRST AMENDMENT to the EMPLOYMENT AGREEMENT between RON BENTSUR and KERYX BIOPHARMACEUTICALS, INC. (Filed With SEC on January 19, 2012)

Amendment to License and Cooperation Agreement for Perifosine between terna Zentaris GmbH (formerly Zentaris GmbH) Weismllerstrae 50 D 60314 Frankfurt Germany - herein Zentaris or... (Filed With SEC on May 10, 2011)

Keryx Biopharmaceuticals, Inc. (Filed With SEC on May 9, 2011)

Alston&Bird llp 90 Park Avenue New York, NY 10016 ###-###-#### Fax ###-###-#### www.alston.com (Filed With SEC on May 9, 2011)

KERYX BIOPHARMACEUTICALS,INC. SECOND AMENDED AND RESTATED DIRECTORSEQUITY COMPENSATION PLAN KERYX BIOPHARMACEUTICALS,INC. SECOND AMENDED AND RESTATED DIRECTORSEQUITY COMPENSATION... (Filed With SEC on August 9, 2010)

SECURITIESPURCHASE AGREEMENT (Filed With SEC on October 1, 2009)

COMMONSTOCK GREENSHOE WARRANT KeryxBiopharmaceuticals, Inc. (Filed With SEC on October 1, 2009)

_________________________________ EMPLOYMENTAGREEMENT BETWEEN RONBENTSUR AND KERYXBIOPHARMACEUTICALS, INC. _________________________________ EMPLOYMENTAGREEMENT (Filed With SEC on September 16, 2009)

AMENDEDAND RESTATED SUBLICENSE AGREEMENT (Filed With SEC on August 12, 2009)

SETTLEMENTAGREEMENT AND GENERAL RELEASE (Filed With SEC on August 12, 2009)

FIRST AMENDMENTTO AMENDED & RESTATEDLICENSE AGREEMENT (Filed With SEC on March 31, 2009)

AMENDED & RESTATED LICENSE AGREEMENT (Filed With SEC on May 12, 2008)

SUBLICENSE AGREEMENT (Filed With SEC on March 27, 2008)

SUBLICENSE AGREEMENT (Filed With SEC on November 9, 2007)

EMPLOYMENT AGREEMENT (Filed With SEC on May 7, 2007)

KERYX BIOPHARMACEUTICALS, INC. 2007 CHIEF ACCOUNTING OFFICER INDUCEMENT STOCK OPTION PLAN SPECIAL NONSTATUTORY STOCK OPTION AGREEMENT (Filed With SEC on May 7, 2007)

KERYX BIOPHARMACEUTICALS, INC. 2007 GENERAL COUNSEL INCENTIVE STOCK OPTION PLAN SPECIAL NONSTATUTORY STOCK OPTION AGREEMENT (Filed With SEC on May 7, 2007)

LICENSE AGREEMENT (Filed With SEC on November 8, 2006)

ASSIGNMENT AND ASSUMPTION AGREEMENT (Filed With SEC on November 8, 2006)

AMENDMENT TO THE KERYX BIOPHARMACEUTICALS, INC. 2004 LONG-TERM INCENTIVE PLAN (Filed With SEC on August 9, 2006)

AMENDMENT TO THE KERYX BIOPHARMACEUTICALS, INC. 2004 LONG-TERM INCENTIVE PLAN (Filed With SEC on May 10, 2006)

W I T N E S S E T H: (Filed With SEC on April 6, 2006)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on March 30, 2006)

EMPLOYMENT AGREEMENT (Filed With SEC on March 8, 2006)

LICENSE AGREEMENT (Filed With SEC on March 8, 2006)

Dated as of January 1, 2001 (Filed With SEC on March 30, 2004)

SUBLICENSE AGREEMENT (Filed With SEC on March 30, 2004)

AMENDMENT TO SUBLICENSE AGREEMENT (Filed With SEC on March 30, 2004)

PUBLIC HEALTH SERVICE PATENT LICENSE AGREEMENT-EXCLUSIVE COVER PAGE (Filed With SEC on March 30, 2004)

RELEASE AGREEMENT (Filed With SEC on March 30, 2004)

COMPREHENSIVE RELEASE AGREEMENT (Filed With SEC on March 30, 2004)

License and Cooperation Agreement FOR PERIFOSINE by and between Zentaris AG Weismüllerstr. 45 60314 Frankfurt am Main Germany - herein "Zentaris" - and AOI Pharma, Inc. 750... (Filed With SEC on March 30, 2004)

OMITTED INFORMATION IS THE SUBJECT OF A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24B-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND HAS BEEN FILED SEPARATELY WITH THE... (Filed With SEC on March 30, 2004)

Cooperative Research and Development Agreement (CACR - 0774) Clinical Development of Perifosine Sherry Ansher, Ph.D. Janet Dancey, M.D. CTEP DCTD Dr. rer. nat. RainerVoegeli ASTA... (Filed With SEC on March 30, 2004)

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KERYX BIOPHARMACEUTICALS INC Contracts & Agreements