Compromise Agreement, dated as of October 5, 2019, by and between Jazz Pharmaceuticals Ireland Limited and Paul Treacy

(Each a “Party” and collectively the “Parties”)

IT IS HEREBY AGREED as follows:

After deleting such material, the Employee shall at the Company’s request warrant in writing that he has complied with this clause.

Except as disclosure may be required by law (including corporate filing requirements), the Parties agree that the terms of this Agreement are confidential as between the Parties and that they shall not voluntarily divulge or publish, directly or indirectly, any information whatsoever regarding the substance, terms or existence of this Agreement. Notwithstanding the foregoing, the Parties may disclose this Agreement to their legal and other professional advisors, and the Employee may disclose this Agreement in confidence to his immediate family members.

The Employee shall not at any time make any negative or adverse remarks whatsoever concerning the Company or any Associated Undertaking or any of its or their shareholders, directors, officers, employees or agents or concerning the business, operations, technologies, products, services, marketing strategies, pricing policies, management affairs, financial condition, systems and procedures, controls, books and records, or service provider of the Company or any Associated Undertaking. The following individuals shall be instructed not to make negative or adverse remarks whatsoever concerning the Employee’s employment with the Company: Bruce Cozadd, Chief Executive Officer; Daniel Swisher, President and Chief Operating Officer; Heidi Manna, Chief Human Resources Officer; and the members of the Board of Directors of Jazz Pharmaceuticals plc.

The Employee acknowledges that the payment of the Termination Payment is conditional upon the Employee signing and returning the Supplemental Waiver of Claims (set out in Schedule A to this Agreement) to Heidi Manna, Chief Human Resources Officer, on or within 7 days from the Termination Date.

of such matters and each Party acknowledges that in agreeing to enter into this Agreement they have not relied on any representations or warranties except for those contained in this Agreement.

Jazz Pharmaceuticals Ireland Limited

Fifth Floor,

Waterloo Exchange,

Waterloo Road,

Dublin 4

Dear Sirs

I refer to the ex gratia Termination Payment referenced in clause 3.1 of the Compromise Agreement between me and Jazz Pharmaceuticals Ireland Limited (the “Company”), to be paid to me by the Company in connection with the termination of my employment.

The term “Termination Date” has the same meaning as in the Compromise Agreement that I entered into with the Company.

I confirm that I have not made a claim under section 123, section 201 or Schedule 3 of the Taxes Consolidation Act 1997 (as amended) within the period of ten years prior to the Termination Date.

I further confirm that the aggregate amount of all tax free payments made to me in respect of any and all ex-gratia payments received by me during my lifetime, including the tax exempt amount in respect of the proposed ex-gratia payment in clause 3.1 of the Compromise Agreement, does not exceed the limit of €200,000 as set out in section 201(8) of the Taxes Consolidation Act 1997 (as amended).

I am entitled to receive a tax-free lump sum in the future under the Company’s occupational pension plan. The net present value as at the Termination Date of the future tax-free lump sum is approximately €164,491.70

In further consideration of the terms and conditions of the Compromise Agreement executed by me on 05 October 2019, I accept the terms and conditions of this supplemental waiver of claims (“Waiver”) and waive as a full and final settlement, and satisfaction of any and all claims, actions or causes of action, suits, complaints, contracts or liabilities of whatsoever nature made and/or which may be made by me in Ireland and/or in any other jurisdiction anywhere in the world against the Company and any Associated Undertakings and/or each and all of their respective directors, officers, employees, shareholders and agents in connection with and/or arising out of and/or concerning my employment with the Company and/or the termination of such employment.

Without prejudice to the generality of the foregoing, I hereby acknowledge and agree that the provisions made in the Compromise Agreement constitute a full and final settlement of all claims, actions or causes of action and demands made and/or which may be made by me against the Company, any Associated Undertakings and the other persons referred to above, whether such claims arise at common law, in equity, pursuant to Statute (including but not limited to the Redundancy Payments Acts 1967 - 2014; the Terms of Employment (Information) Acts 1994 -2014; the Minimum Notice and Terms of Employment Acts 1973 - 2005; the Protection of Employment Act 1977-2014; the Protection of Employment (Exceptional Collective Redundancies and Related Matters) Act 2007; the Organisation of Working Time Act 1997; the Payment of Wages Act 1991; the Unfair Dismissals Acts 1977 - 2015; the Protected Disclosures Act 2014; the Employment Equality Acts 1998 - 2015; the European Communities (Protection of Employees on Transfer of Undertakings) Regulations 2003; the Maternity Protection Acts 1994 and 2004; the Adoptive Leave Acts 1995 and 2005; the Parental Leave Acts 1998 and 2006; the Paternity Leave and Benefit Act 2016; the National Minimum Wage Acts 2000 and 2015; the Carer’s Leave Act 2001 (as amended); the Protection of Employees (Part-Time Work) Act 2001; the Protection of Employees (Fixed-Term Work) Act 2003; the Industrial Relations Acts, 1946 - 2015; the Data Protection Acts 1988 - 2018; the Workplace Relations Act 2015; the Employment (Miscellaneous Provisions) Act 2018, and the Safety Health and Welfare at Work Act 2005-2014) or pursuant to contract, in tort (including personal injury claims) or otherwise, howsoever arising.

I acknowledge that I have read, advised of and been given an opportunity to take legal advice on the Compromise Agreement and the provisions hereof and that I understand, accept and agree to the contents of the same and, furthermore, that I am signing this Waiver voluntarily without coercion of any description and with full understanding that I am releasing and compromising any and all claims and demands of every nature whatsoever that I have or might have against the Company and its Associated Undertakings and the other persons referred to above, save only in respect of the obligations of the Company as set out in the Compromise Agreement.