DEBT AND WARRANT SETTLEMENT AGREEMENT

Exhibit 10.53

DEBT AND WARRANT SETTLEMENT AGREEMENT

THIS DEBT AND WARRANT SETTLEMENT AGREEMENT (“Agreement”) dated this 31st day of March, 2017 (the “Agreement Date”), is made and entered into by and among (i) Dorsar Investment Company (together with all affiliates, collectively referred to herein as “Dorsar”), (ii) Alco Investment Company (“Alco”), (iii) Two Daughters LLC (“Two Daughters” and, together with Dorsar and Alco, collectively, the “Feinberg Parties” and each, individually, a “Feinberg Party”), (iv) Agent (as defined below) and (v) Napo Pharmaceuticals, Inc., a Delaware corporation (“Company”).

1.              RECITALS

a.             Company is indebted to the Feinberg Parties pursuant to the terms of (i) that certain Amendment and Extension of Convertible Promissory Note, Series No. 2014-1, dated April 30, 2014, by Company in favor of Dorsar in the original principal amount of $632,020.92 (as amended, modified or supplemented, the “Dorsar Note”), (ii) that certain Amendment and Extension of Convertible Promissory Note, Series No. 2014-2, dated April 30, 2014, by Company in favor of Alco in the original principal amount of $1,274,235.61 (as amended, modified or supplemented, the “Alco Note”) and (iii) that certain Amendment and Extension of Convertible Promissory Note, Series No. 2014-3, dated April 30, 2014, by Company in favor of Two Daughters in the original principal amount of $100,668.86 (as amended, modified or supplemented, the “Two Daughters Note” and together with the Dorsar Note and the Alco Note, collectively, the “Notes” and each, individually, a “Note”).  The Notes are secured by that certain Subordinated Pledge and Security Agreement (as amended, modified or supplemented, the “Security Agreement”) dated as of October 10, 2014 by Company in favor of Dorsar in its capacity as collateral agent for the Feinberg Parties (“Agent”).  The security interests granted pursuant to the Security Agreement have been perfected by a UCC-1 Financing Statement (the “UCC-1”) naming Company as debtor and recorded with the Secretary of State of the State of Delaware on or about October 10, 2014.  The Notes are further secured pursuant to a Stock Pledge Agreement by certain stock pledged by Lisa A. Conte (the “Pledge Agreement”).

b.             Company has issued to each Feinberg Party certain warrants for the purchase of common stock of Company, including, without limitation, those warrants identified on Schedule 1 attached hereto (the “Existing Warrants”).

c.             As of January 31, 2017, the (i) unpaid principal balance of the Dorsar Note is $416,346.64 and the accrued, but unpaid interest thereon is $211,250.63, (ii) unpaid principal balance of the Alco Note is $839,404.17 and the accrued, but unpaid interest thereon is $425,907.00 and (iii) the unpaid principal balance of the Two Daughters Note is $65,399.46 and the accrued, but unpaid interest thereon is $33,257.27.

d.             As a complete settlement and satisfaction of the loans evidenced by the Notes, Company has offered, subject to the terms and conditions hereof, to (i) pay in kind all outstanding obligations of Company under the Dorsar Note by, pursuant to the Merger

Agreement (as defined below), causing Jaguar (as defined below) to issue and deliver to Dorsar upon consummation of the Merger (as defined below) 678,483 non-voting shares of common stock of Jaguar (the “Dorsar Debt Settlement Securities”), (ii) pay in kind all outstanding obligations of Company under the Alco Note by, pursuant to the Merger Agreement, causing Jaguar to issue and deliver to Alco upon consummation of the Merger 1,367,903 non-voting shares of common stock of Jaguar (the “Alco Debt Settlement Securities”) and (iii) pay in kind all outstanding obligations of Company under the Two Daughters Note by, pursuant to the Merger Agreement, causing Jaguar to issue and deliver to Two Daughters upon consummation of the Merger 106,655 non-voting shares of common stock of Jaguar (the “Two Daughters Debt Settlement Securities” and, together with the Dorsar Debt Settlement Securities and the Alco Debt Settlement Securities, collectively, the “Debt Settlement Securities”).

e.             Pursuant to the terms of the Merger Agreement, in settlement and exchange for the Existing Warrants, (i) Dorsar will receive, upon consummation of the Merger, warrants to purchase, in the aggregate, 995,855 shares of common stock of Jaguar at $0.08 per share (the “Dorsar Exchange Warrants”), (ii) Alco will receive, upon consummation of the Merger, warrants to purchase 223,751 shares of common stock of Jaguar at $0.08 per share (the “Alco Exchange Warrants”) and (iii) Two Daughters will receive, upon consummation of the Merger, warrants to purchase 17,677 shares of common stock of Jaguar at $0.08 per share (the “Two Daughters Exchange Warrants” and, together with the Dorsar Exchange Warrants and Alco Exchange Warrants, collectively, the “Exchange Warrants”).

f.             The Feinberg Parties are willing to accept Company’s offer to pay in kind the obligations of the Company under the Notes to such Feinberg Parties by delivering the applicable Debt Settlement Securities to such Feinberg Parties, and to accept the Exchange Warrants in exchange for the Existing Warrants, in each case, upon consummation of the Merger, as a complete settlement and satisfaction of the Loan, upon the terms and conditions set forth in this Agreement.

g.             All Debt Settlement Securities and Exchange Warrants shall be appropriately adjusted for any stock splits, combinations, reclassifications, reorganizations and similar transactions effected after the Effective Date as necessary to reflect the intention of the parties hereto. The Debt Settlement Securities, Warrants and all securities underlying and/or issuable under the Warrants, collectively, the “Debt Settlement Securities”)

2.     CONDITIONS PRECEDENT.  The following are conditions precedent to the Feinberg Parties’ obligations under Section 5 of this Agreement:

a.             Receipt by Agent of a fully executed copy of this Agreement.

b.             Receipt by Agent of a fully executed copy of that certain Agreement and Plan of Merger (the “Merger Agreement”) between Company and Napo Acquisition Corporation, a Delaware corporation (“Merger Sub”), a wholly owned subsidiary of Jaguar Animal Health, Inc., a Delaware corporation (“Jaguar”) in substantially the form attached hereto as Exhibit A.

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c.             The consummation of the merger between Company and Merger Sub pursuant to the terms of the Merger Agreement (the “Merger”).

d.             The representations and warranties of the Company contained in this Agreement are true and correct in all material respects on the date hereof.

e.             Upon consummation of the Merger Company shall deliver or cause to be delivered to Agent, for the benefit of the applicable Feinberg Parties, certificates representing the Debt Settlement Securities.

f.             Upon consummation of the Merger Company shall deliver or cause to be delivered to Agent, for the benefit of the applicable Feinberg Parties, the Exchange Warrants.

3.     COMPANY’S REPRESENTATIONS AND WARRANTIES.  Company represents and warrants that:

a.             it is duly authorized to execute this Agreement and has all requisite power, authority, and approval required to enter into, execute, and deliver this Agreement;

b.             this Agreement is the legal, valid and binding obligation of Company enforceable against Company in accordance with its terms (except as such enforcement may be limited by bankruptcy, insolvency, reorganization, receivership, moratorium or other laws or equitable principles limiting to the rights of creditors generally); and

c.             it has the right to enter into this Agreement without the consent of any third party (other than consents which have been obtained) and the execution and delivery of this Agreement does not violate any agreement to which Company is a party or otherwise bound (after giving effect to contemporaneous amendments and consents to any such agreements).

4.     FEINBERG PARTIES’ REPRESENTATIONS AND WARRANTIES.  Each Feinberg Party represents and warrants to Company and Jaguar that:

a.             Agent and each Lender have all necessary power and authority to execute and deliver this Agreement and to carry out its provisions.  All action on Agent’s and each Lenders’ part required for the lawful execution and delivery of this Agreement has been taken.  Upon its execution and delivery, this Agreement will be a valid and binding obligation of Agent and each Lender, enforceable in accordance with its terms (except as such enforcement may be limited by bankruptcy, insolvency, reorganization, receivership, moratorium or other laws or equitable principles limiting to the rights of creditors generally).

b.             Agent and each Lender are aware that the Debt Settlement Securities to be issued to each Lender have not been registered under the Securities Act of 1933, as amended (the “Securities Act”), and that the Debt Settlement Securities are deemed to constitute “restricted securities” under Rule 144 promulgated under the Securities Act (“Rule 144”).  Agent and each Lender also understand that the Debt Settlement Securities are being offered and sold pursuant to

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an exemption from registration contained in the Securities Act based in part upon each Lenders’ representations contained in this Agreement.

c.             Each Lender is obtaining the Debt Settlement Securities for such Lender’s own account and each such Lender has no present intention of distributing or selling the securities except as permitted under the Securities Act and applicable state securities laws.

d.             Each Lender has sufficient knowledge and experience in business and financial matters to evaluate Jaguar, its proposed activities and the risks and merits of this investment.  Each Lender has the ability to accept the high risk and lack of liquidity inherent in this type of investment.  Each Lender has conducted its own independent investigation of Jaguar and has reached its own conclusions regarding the risks and merits of this investment.  No Lender is relying upon any representations or warranties from Company or Jaguar except as explicitly set forth herein.

e.             Each Lender had an opportunity to discuss Jaguar’s business, management and financial affairs with directors, officers and management of Jaguar.  Each Lender has also had the opportunity to ask questions of and receive answers from Jaguar and its management regarding the terms and conditions of this investment.  Each Lender understands the significant risks of this investment.

f.             Each Lender has the capacity to protect its own interests in connection with the purchase of the Debt Settlement Securities by virtue of its business or financial expertise.

g.             Each Lender understands that the Debt Settlement Securities must be held indefinitely unless they are subsequently registered under the Securities Act or an exemption from such registration is available.  Each Lender has been advised or is aware of the provisions of Rule 144, as in effect from time to time, which permit limited resale of shares purchased in a private placement subject to the satisfaction of certain conditions, including, among other things, the availability of certain current public information about Jaguar, the resale occurring following the required holding period under Rule 144, and the number of shares being sold during any three month period not exceeding specified limitations.

h.             Each Lender acknowledges and agrees that the Debt Settlement Securities upon issuance shall bear customary restrictive legends referencing their restrictions on transfer in accordance with the Securities Act.

i.              If Agent or any Lender is not a United States person (as defined by Section 7701(a)(30) of the Internal Revenue Code of 1986, as amended (the “Code”)), Agent and each such Lender, as applicable, hereby represents that Agent and such Lender, as applicable, has satisfied itself as to the full observance of the laws of its jurisdiction in connection with any invitation to subscribe for or otherwise acquire the Debt Settlement Securities or any use of this Agreement, including (i) the legal requirements within its jurisdiction for the purchase of the Debt Settlement Securities, (ii) any foreign exchange restrictions applicable to such purchase, (iii) any government or other consents that may need to be obtained in connection with such purchase, and (iv) the income tax and other tax consequences, if any, that may be relevant to the

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purchase, holding, redemption, sale or transfer of the Debt Settlement Securities.  Jaguar’s offer and sale and each Lender’s subscription and payment for and continued beneficial ownership of (or Company’s transfer of, as applicable) the Debt Settlement Securities will not violate any applicable securities or other laws of Agent’s or any Lenders’ jurisdiction.

j.              Agent and each Lender has reviewed this Agreement in its entirety, has had an opportunity to obtain the advice of counsel prior to executing this Agreement and fully understands all provisions of this Agreement. Agent and each Lender acknowledges that no other representations or warranties, oral or written, have been made by Company or any agent thereof except as set forth in this Agreement.

k.             The office or offices of Agent and each Lender in which its investment decision was made is located at the address or addresses of Agent and each such Lender set forth on the signature page hereto.

l.              Each Lender is an “accredited investor” as that term is defined under Regulation D promulgated under the Securities Act.

m.           Agent and each Lender is aware that Company and Jaguar are relying on the accuracy of the above representations to establish compliance with Federal and State securities laws.  If any such warranties or representations are not true and accurate in any respect as of the Effective Date (as defined below), Agent shall so notify Company in writing immediately and shall be cause for rescission by Company at its sole election.  Agent and each Lender represents that neither Agent, any Lender, nor any person or entity with whom Agent or any Lender shares beneficial ownership of Jaguar’s securities, is subject to any of the “Bad Actor” disqualifications described in Rule 506(d)(1)(i) to (viii) under the Securities Act, attached hereto as Annex I.

5.     FEINBERG PARTIES’ OBLIGATIONS AND AGREEMENTS.  Upon satisfaction (or waiver by Agent) of the conditions precedent in Section 2 of this Agreement (the “Effective Date”), Agent and the Feinberg Parties agree that:

a.             all Obligations and liabilities of Company and its affiliates under the Notes, the Security Agreement and all other documents executed or delivered in connection therewith (collectively, the “Loan Documents”) shall be deemed paid in full and extinguished;

b.             neither Agent nor any Feinberg Party shall have any further rights under the Note, the Security Agreement or any other Loan Document;

c.             neither Company nor any of its affiliates shall have any further obligation under the Notes, the Security Agreement or any of the other Loan Documents;

d.             the Notes, the Security Agreement, the Pledge Agreement and all other Loan Documents shall automatically terminate and be of no further force and effect;

e.             all security interests and liens granted to the Agent or any Feinberg Party on any personal property (including, but not limited to, any intellectual property) and real property of

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the Company and any of its affiliates under the Security Agreement or otherwise to secure the obligations of Company under the Notes are automatically terminated and of no further force and effect;

f.             all security interests and liens granted to the Agent or any Feinberg Party on any personal property of Lisa A. Conte pursuant to the Pledge Agreement or otherwise to secure the obligations of Company under the Notes are automatically terminated and of no further force and effect;

g.             the Company, its affiliates and designees are hereby authorized to file on behalf of Agent and any Feinberg Party, all Uniform Commercial Code termination statements with respect to any UCC financing statements filed by or on behalf of Agent and/or such Feinberg Party against Lisa A. Conte, the Company or any of its affiliates, including, without limitation, the UCC-1;

h.             the Agent each Feinberg Party will promptly (y) deliver to the Company or Lisa A. Conte, as applicable, all possessory collateral held by the Agent or such Feinberg Party and (z) deliver such other documents and take such other actions as Company may request in order to effectuate the termination of the Company’s obligations under the Notes and the release and termination of its security interests in the property of Company and its affiliates; and

i.              each Feinberg Party will promptly deliver to Company its original Note and all Existing Warrants held by such Feinberg Party, marked cancelled.

6.     FORBEARANCE.  In reliance upon Company’s representations, warranties and covenants contained in this Agreement, and subject to the terms and conditions of this Agreement, the Agent and the Feinberg Parties hereby agree, during the period commencing on the Agreement Date and ending at 5:00 pm Eastern Time on July 31, 2017 to forbear from exercising any of their respective rights and remedies under the Notes, the Security Agreement, any other agreement or document relating thereto, applicable law or otherwise, or in any way seeking to collect the amounts owed under the Notes except as expressly contemplated in this Agreement, including without limitation, by commencing any proceeding with respect thereto, as a result of any default, event of default or other breach occurring under any such Notes, Security Agreement or other agreement relating thereto.

7.     MUTUAL RELEASE.  In consideration of the agreements set forth herein, Company, Agent and each Feinberg Party hereby agree as follows, effective upon consummation of the Merger and satisfaction of all other Conditions Precedent in Section 2:

a.             Release by Company:

i.                      Company does hereby release, acquit and forever discharge Agent, each Feinberg Party and their respective past and present officers, directors, attorneys, affiliates, members, managers, employees and agents, of and from any and all claims, demands, obligations, liabilities, indebtedness, breaches of contract, breaches of duty or of any relationship, acts,

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omissions, misfeasance, malfeasance, causes of action, defenses, offsets, debts, sums of money, accounts, compensation, contracts, controversies, promises, damages, costs, losses and expenses, of every type, kind, nature, description or character, whether known or unknown, suspected or unsuspected, liquidated or unliquidated, each as though fully set forth herein at length (each, a “Company Released Claim” and collectively, the “Company Released Claims”), that Company hereunder has as of the date of the consummation of the Merger or may acquire in any way arising out of, connected with or related to the Notes or any Loan Document.

ii.                  Each person signing below on behalf of Company hereunder acknowledges that he or she has read each of the provisions of this Section 7(a).  Each such person fully understands that this Section 7(a) has important legal consequences, and each such person realizes that they are releasing any and all Company Released Claims that Company may have.  Company hereby acknowledges that each of them has had an opportunity to obtain a lawyer’s advice concerning the legal consequences of each of the provisions of this Section 7(a).

iii.              Company hereby specifically acknowledges and agrees that:  (i) none of the provisions of this Section 7(a) shall be construed as or constitute an admission of any liability on the part of Agent or any Feinberg Party; (ii) the provisions of this Section 7(a) shall constitute an absolute bar to any Company Released Claim of any kind, whether any such Company Released Claim is based on contract, tort, warranty, mistake or any other theory, whether legal, statutory or equitable; and (iii) any attempt to assert a Company Released Claim barred by the provisions of this Section 7(a) shall subject Company to the provisions of applicable law setting forth the remedies for the bringing of groundless, frivolous or baseless claims or causes of action.

iv.               Company expressly waives any and all rights and benefits conferred upon it by Section 1542 of the Civil Code of the State of California (and any similar or like statute or other law which may be applicable), which states as follows:

“A general release does not extend to claims which the creditor does not know or suspect to exist in his or her favor at the time of executing the release, which if known by him or her must have materially affected his or her settlement with the debtor.”

Company expressly agrees and understands that the release given by it pursuant to this provision applies to all unknown, unsuspected and unanticipated Claims which it may have against Agent and the Feinberg Parties that it has released.  Company understands and acknowledges that the significance and consequence of this waiver of Section 1542 of the California Civil Code (and any similar or like statute or other law which

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may be applicable) is that even if it should eventually suffer additional damages relating in any way to any dispute, that Company will not be permitted to make any claim for those damages against Agent and the Feinberg Parties that it has released pursuant to this Agreement.  Furthermore, Company acknowledges that it intends these consequences even as to claims for damages that may now exist as of the date of this Agreement but which are not known to exist, and which, if known would materially affect its decision to execute these releases, regardless of whether their lack of knowledge, or the lack of knowledge of any one of them, is the result of ignorance, oversight, error, negligence, or any other cause.

b.             Release by Agent and the Feinberg Parties.

i.                      Agent and each Feinberg Party hereunder, for itself and on behalf of its respective successors and assigns, do hereby release, acquit and forever discharge Company and Jaguar and all of their respective past and present officers, directors, attorneys, affiliates, employees and agents, of and from any and all claims, demands, obligations, liabilities, indebtedness, breaches of contract, breaches of duty or of any relationship, acts, omissions, misfeasance, malfeasance, causes of action, defenses, offsets, debts, sums of money, accounts, compensation, contracts, controversies, promises, damages, costs, losses and expenses, of every type, kind, nature, description or character, whether known or unknown, suspected or unsuspected, liquidated or unliquidated, each as though fully set forth herein at length (each, a “Feinberg Party Released Claim” and collectively, the “Feinberg Party Released Claims”), that Agent or any Feinberg Party hereunder now has as of the date of the consummation of the Merger or may acquire in any way arising out of, connected with or related to the Notes or any Loan Document.

ii.                  Each person signing below on behalf of Agent or any Feinberg Party hereunder acknowledges that he or she has read each of the provisions of this Section 7(b).  Each such person fully understands that this Section 7(b) has important legal consequences, and each such person realizes that they are releasing any and all Feinberg Party Released Claims that Agent or any such Feinberg Party may have.  Agent and each Feinberg Party hereunder hereby acknowledge that each of them has had an opportunity to obtain a lawyer’s advice concerning the legal consequences of each of the provisions of this Section 7(b).

iii.              Agent and each Feinberg Party hereby specifically acknowledge and agree that:  (i) none of the provisions of this Section 7(b) shall be construed as or constitute an admission of any liability on the part of Company; (ii) the provisions of this Section 7(b) shall constitute an absolute bar to any Feinberg Party Released Claim of any kind, whether any such Feinberg

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Party Released Claim is based on contract, tort, warranty, mistake or any other theory, whether legal, statutory or equitable; and (iii) any attempt to assert a Feinberg Party Released Claim barred by the provisions of this Section 7(b) shall subject Agent and each Feinberg Party to the provisions of applicable law setting forth the remedies for the bringing of groundless, frivolous or baseless claims or causes of action.

iv.               Agent and each Feinberg Party expressly waives any and all rights and benefits conferred upon it by Section 1542 of the Civil Code of the State of California (and any similar or like statute or other law which may be applicable), which states as follows:

“A general release does not extend to claims which the creditor does not know or suspect to exist in his or her favor at the time of executing the release, which if known by him or her must have materially affected his or her settlement with the debtor.”

Agent and each Feinberg Party expressly agrees and understands that the release given by it pursuant to this provision applies to all unknown, unsuspected and unanticipated Claims which it may have against the Company that it has released.  Agent and each Feinberg Party understands and acknowledges that the significance and consequence of this waiver of Section 1542 of the California Civil Code (and any similar or like statute or other law which may be applicable) is that even if it should eventually suffer additional damages relating in any way to any dispute, that neither Agent nor any Feinberg Party will be permitted to make any claim for those damages against the Company that it has released pursuant to this Agreement.  Furthermore, Agent and each Feinberg Party acknowledges that it intends these consequences even as to claims for damages that may now exist as of the date of this Agreement but which are not known to exist, and which, if known would materially affect its decision to execute these releases, regardless of whether their lack of knowledge, or the lack of knowledge of any one of them, is the result of ignorance, oversight, error, negligence, or any other cause.

8.             REGISTRATION RIGHTS.  Company represents that as a condition of the Merger Agreement, Company, Agent and each Feinberg Party agree, that the following terms shall be effective upon consummation of the Merger:

a.             No later than thirty (30) days following the consummation of the Merger (the “Filing Date”), Jaguar shall prepare and file with the Securities and Exchange Commission (the “Commission”), a Registration Statement on Form S-3 (or such other form available) covering the public resale of the Debt Settlement Securities and shall cause such Registration Statement to be filed by the Filing Date for such Registration Statement and use reasonable best efforts to have the Registration Statement declared effective under the Securities Act as soon as possible thereafter (the “Effectiveness Date”).  Jaguar shall use its reasonable best efforts to keep such

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Registration Statement continuously effective under the Securities Act during the entire Effectiveness Period.

b.             Each Feinberg Party agrees to furnish to Jaguar a completed selling stockholder questionnaire in the customary form to be presented to such Feinberg Party.  Jaguar shall not be required to include the Debt Settlement Securities in the Registration Statement if any Feinberg Party fails to furnish to Jaguar a fully completed questionnaire at least two Trading Days prior to the Effectiveness Date.

c.             Notwithstanding anything in this Section to the contrary, Jaguar may delay or suspend the effectiveness of the Registration Statement for up to thirty (30) days (a “Delay Period”) if the board of directors of Jaguar determines in good faith that (i) effectiveness of the Registration Statement must be suspended in accordance with the rules and regulations under the Securities Act or that (ii) the disclosure of material non-public information (“Pending Developments”) at such time would be detrimental to Jaguar and its subsidiaries, taken as a whole.  Notwithstanding the foregoing, Jaguar shall use its reasonable best efforts to ensure that the Registration Statement is declared effective and its permitted use is resumed following a Delay Period as promptly as practicable.

d.             In addition to the covenants set forth herein, following the consummation of the Merger, Jaguar shall:

(i)            furnish to Agent such reasonable number of copies of the registration statement, preliminary prospectus, final prospectus and such other documents as it may reasonably request in order to facilitate the public offering of the Debt Settlement Securities;

(ii)           use its reasonable best efforts to register or qualify the Debt Settlement Securities under such state securities or blue sky laws of such jurisdictions as any Feinberg Party may reasonably request in writing within twenty (20) days following the original filing of such registration statement, except that Jaguar shall not for any purpose be required to execute a general consent to service of process or to qualify to do business as a foreign corporation in any jurisdiction wherein it is not so qualified;

(iii)          notify Agent, promptly after it shall receive notice thereof, of the time when such registration statement or a supplement to any prospectus forming a part of such registration statement has become effective;

(iv)          notify Agent promptly of any request by the Staff of the Commission for the amending or supplementing of such registration statement or prospectus or for additional information;

(v)           prepare and file with the Commission any amendments or supplements to such registration statement or prospectus which is required under the Securities Act or the rules and regulations promulgated thereunder in connection with the distribution of the Debt Settlement Securities;

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(vi)          prepare and promptly file with the Commission and promptly notify Agent of the filing of such amendment or supplement to such registration statement or prospectus as may be necessary to correct any statements or omissions if, at the time when a prospectus relating to the Debt Settlement Securities is required to be delivered under the Securities Act, any event shall have occurred as the result of which any such prospectus or any other prospectuses then in effect would include an untrue statement of a material fact or omit to state any material fact necessary to make the statements therein, in the light of the circumstances in which they were made, not misleading;

(vii)         advise Agent promptly after it shall receive notice or obtain knowledge thereof, of the issuance of any stop order by the Division of Enforcement of the Commission suspending the effectiveness of such registration statement or the initiation or threatening of any proceeding for that purpose and promptly use its reasonable best efforts to prevent the issuance of any stop order or to obtain its withdrawal if such stop order should be issued; and

(viii)        indemnify and hold harmless each Feinberg Party against any and all losses, claims, damages or liabilities to which such Feinberg Party shall become subject, under the Securities Act or otherwise, that arise out of or are based upon any untrue statement or alleged untrue statement of any material fact contained in the effective registration statement or any prospectus that forms a part thereof or any amendment or supplement thereto, or arise out of or are based upon any omission or alleged omission to state therein a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading; provided, however, that no such indemnification shall be available to any Feinberg Party (and each Feinberg Party shall indemnify and hold harmless Jaguar) with respect to, and to the extent there is liability attributable to, written information provided by any Feinberg Party to Jaguar for use in such registration statement or prospectus thereunder or any amendment or supplement thereto, or any related preliminary prospectus.

e.             All fees and expenses incident to the performance of or compliance with this Section by Jaguar shall be borne by Jaguar whether or not any Debt Settlement Securities are sold pursuant to a Registration Statement.

f.             As used in this Section, the following terms have the respective meanings:

“Change of Control” means (i) any merger, consolidation or other business combination of Jaguar with any entity in which the stockholders of Jaguar immediately prior to such transaction in the aggregate cease to own at least 50% of the voting power of the voting securities of the entity surviving or resulting from such transaction (or the ultimate parent thereof), or (ii) any sale, transfer, lease, assignment or other disposal of all or substantially all of the assets of Jaguar and its subsidiaries, taken as a whole.

“Effectiveness Period” means, the period commencing on the Effectiveness Date of the Registration Statement and ending on the earlier of (i) the time as all of the Debt

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Settlement Securities covered by such Registration Statement have been sold (either pursuant to a Registration Statement or otherwise), (ii) the time as all of the Debt Settlement Securities are eligible to be sold by the Holders without compliance with the volume limitations or public information requirements of Rule 144; or (iii) a Change of Control.

“Holder” or “Holders” means the holder or holders, as the case may be, from time to time, of the Debt Settlement Securities.

“Registration Statement” means the registration statements required to be filed in accordance with this Section and any additional registration statements required to be filed under this this Section, including in each case the prospectus, amendments and supplements to such registration statements or prospectus, including pre and post effective amendments, all exhibits thereto, and all material incorporated by reference or deemed to be incorporated by reference therein.

“Trading Day” means a day on which the Nasdaq Stock Market is open for trading.

9.              GENERAL PROVISIONS

a.             Each party to this Agreement acknowledges and warrants that it has been represented by independent counsel of its own choice throughout all negotiations which preceded the negotiation and execution of this Agreement, specifically Kemp Smith LLP has represented the Feinberg Parties and Agent and Boies, Schiller & Flexner LLP has represented the Company.  Each party has read or had read to it all of this Agreement and had it explained to it by its attorney and fully understands all the terms used and their significance;

b.             The parties hereto are sophisticated and have been represented by attorneys throughout the transactions contemplated hereby who have carefully negotiated the provisions hereof.  As a consequence, the parties do not intend that the presumptions of laws or rules relating to the interpretation of contracts against the drafter of any particular clause should be applied to this Agreement or any agreement or instrument executed in connection herewith, and therefore waive their effects;

c.             Each of the parties to this Agreement shall bear its own expenses with respect to the negotiation, execution, delivery and enforcement of this Agreement, the transactions referenced herein and all other transactions relating hereto;

d.             This Agreement contains the entire agreement and understanding concerning the subject matter hereof between the parties, and supersedes and replaces all prior negotiations, proposed agreements and agreements written or oral.  Each of the parties to this Agreement acknowledges that no other party to this Agreement, nor any agent or attorney of any such party, has made any promise, representation or warranty whatsoever, express or implied, not contained in this Agreement, to induce him to execute this Agreement.  Each of the parties further acknowledge that he is not executing this Agreement in reliance on any promise, representation or warranty not contained in this Agreement;

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e.             Whenever, in this Agreement, the context may so require, the masculine or neuter gender shall be deemed to refer to and include the feminine, masculine, and neuter, and the singular to refer to and include the plural;

f.             This Agreement shall in all respects be interpreted, enforced and governed by the laws of the State of New York (without reference to conflict of laws rules or principles);

g.             Jaguar is an intended third-party beneficiary of this Agreement;

h.             This Agreement may be executed in several counterparts, all of which shall be an original and enforceable against any party who signed it, and all of which shall constitute one and the same document.  Signatures submitted via facsimile or .pdf email shall be acceptable to bind the parties hereunder;

i.              CONFIDENTIALITY.  The parties agree that the terms of this Agreement, the information contained in this Agreement and all information delivered by or on behalf of Company pursuant to or in connection with this agreement shall remain strictly confidential and neither Agent, Feinberg Party nor Company, shall release any such information to any other person or entity (other than Jaguar, Dorsar Investment Company, Alco Investment Company, Two Daughters LLC, Boies, Schiller & Flexner LLP, Dan Becka, Nantucket Investments Limited and any lender to or equity holder in Company or Jaguar and their respective officers, directors, shareholders, attorneys and advisors), without the prior written consent of the other parties hereto.  Notwithstanding the foregoing, prior written consent of the Agent and the Feinberg Parties shall not be required for the disclosure of information regarding this Agreement to Company’s officers, directors, shareholders, attorneys and advisors and to the extent required by legal process or court order;

j.              EXCLUSIVE JURISDICTION. AGENT, THE FEINBERG PARTIES AND COMPANY AGREE THAT ALL ACTIONS TO ENFORCE THIS AGREEMENT AND ALL DISPUTES AMONG OR BETWEEN THEM ARISING OUT OF, CONNECTED WITH, RELATED TO, OR INCIDENTAL TO THE RELATIONSHIP ESTABLISHED AMONG OR BETWEEN THEM IN CONNECTION WITH THIS AGREEMENT, AND WHETHER ARISING IN CONTRACT, TORT, EQUITY, OR OTHERWISE, SHALL BE RESOLVED ONLY BY A COURT LOCATED IN NEW YORK, NEW YORK, AND AGENT, THE FEINBERG PARTIES AND COMPANY HEREBY CONSENT AND SUBMIT TO THE JURISDICTION OF SUCH COURT;

k.             WAIVER OF RIGHT TO TRIAL BY JURY.  EACH PARTY TO THIS AGREEMENT HEREBY EXPRESSLY WAIVES ANY RIGHT TO TRIAL BY JURY OF ANY CLAIM, DEMAND, ACTION OR CAUSE OF ACTION ARISING UNDER THIS AGREEMENT, OR IN ANY WAY CONNECTED WITH OR RELATED OR INCIDENTAL TO THE DEALINGS OF THE PARTIES HERETO OR ANY OF THEM WITH RESPECT TO THE AGREEMENT (AS NOW OR HEREAFTER MODIFIED) OR ANY OTHER INSTRUMENT, DOCUMENT OR AGREEMENT EXECUTED OR DELIVERED IN CONNECTION HEREWITH, OR THE TRANSACTIONS RELATED HERETO OR

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THERETO, IN EACH CASE WHETHER NOW EXISTING OR HEREAFTER ARISING, AND WHETHER SOUNDING IN CONTRACT OR TORT OR OTHERWISE; AND EACH PARTY HEREBY AGREES AND CONSENTS THAT ANY SUCH CLAIM, DEMAND, ACTION OR CAUSE OF ACTION SHALL BE DECIDED BY COURT TRIAL WITHOUT A JURY, AND THAT ANY PARTY TO THIS AGREEMENT MAY FILE AN ORIGINAL COUNTERPART OR A COPY OF THIS SECTION WITH ANY COURT AS WRITTEN EVIDENCE OF THE CONSENT OF THE PARTIES HERETO TO THE WAIVER OF THEIR RIGHT TO TRIAL BY JURY; AND

l.              Wherever possible, each provision of this Agreement shall be interpreted in such manner as to be valid under applicable law.  To the extent any such provision is found to be invalid or unenforceable under applicable law in a given jurisdiction, then (a) such provision shall be ineffective only to such extent; (b) the remainder of such provision and the other provisions of this Agreement shall remain in full force and effect in such jurisdiction; and (c) such provision shall remain in full force and effect in any other jurisdiction.

[The remainder of this page is intentionally left blank.  Signatures follow.]

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IN WITNESS WHEREOF, Company, Agent and the Feinberg Parties have caused this Agreement to be duly executed as of the date first written above.

Signature Page to

Debt and Warrant Settlement Agreement (Feinberg)

ANNEX I

BAD ACTOR

Rule 506(d)(1)(i) to (viii) under the Securities Act of 1933, as amended

(i) Has been convicted, within ten years before such sale (or five years, in the case of issuers, their predecessors and affiliated issuers), of any felony or misdemeanor:

(A) In connection with the purchase or sale of any security;

(B) Involving the making of any false filing with the Commission; or

(C) Arising out of the conduct of the business of an underwriter, broker, dealer, municipal securities dealer, investment adviser or paid solicitor of purchasers of securities;

(ii) Is subject to any order, judgment or decree of any court of competent jurisdiction, entered within five years before such sale, that, at the time of such sale, restrains or enjoins such person from engaging or continuing to engage in any conduct or practice:

(A) In connection with the purchase or sale of any security;

(B) Involving the making of any false filing with the Commission; or

(C) Arising out of the conduct of the business of an underwriter, broker, dealer, municipal securities dealer, investment adviser or paid solicitor of purchasers of securities;

(iii) Is subject to a final order of a state securities commission (or an agency or officer of a state performing like functions); a state authority that supervises or examines banks, savings associations, or credit unions; a state insurance commission (or an agency or officer of a state performing like functions); an appropriate federal banking agency; the U.S. Commodity Futures Trading Commission; or the National Credit Union Administration that:

(A) At the time of such sale, bars the person from:

(1) Association with an entity regulated by such commission, authority, agency, or officer;

(2) Engaging in the business of securities, insurance or banking; or

(3) Engaging in savings association or credit union activities; or

(B) Constitutes a final order based on a violation of any law or regulation that prohibits fraudulent, manipulative, or deceptive conduct entered within ten years before such sale;

(iv) Is subject to an order of the Commission entered pursuant to section 15(b) or 15B(c) of the Securities Exchange Act of 1934 (15 U.S.C. 78o(b) or 78o-4(c)) or section 203(e) or (f) of the Investment Advisers Act of 1940 (15 U.S.C. 80b-3(e) or (f)) that, at the time of such sale:

(A) Suspends or revokes such person’s registration as a broker, dealer, municipal securities dealer or investment adviser;

(B) Places limitations on the activities, functions or operations of such person; or

(C)Bars such person from being associated with any entity or from participating in the offering of any penny stock;

(v) Is subject to any order of the Commission entered within five years before such sale that, at the time of such sale, orders the person to cease and desist from committing or causing a violation or future violation of:

(A) Any scienter-based anti-fraud provision of the federal securities laws, including without limitation section 17(a)(1) of the Securities Act of 1933 (15 U.S.C. 77q(a)(1)), section 10(b) of the Securities Exchange Act of 1934 (15 U.S.C. 78j(b)) and 17 CFR 240.10b-5, section 15(c)(1) of the Securities Exchange Act of 1934 (15 U.S.C. 78o(c)(1)) and section 206(1) of the Investment Advisers Act of 1940 (15 U.S.C. 80b-6(1)), or any other rule or regulation thereunder; or

(B) Section 5 of the Securities Act of 1933 (15 U.S.C. 77e).

(vi) Is suspended or expelled from membership in, or suspended or barred from association with a member of, a registered national securities exchange or a registered national or affiliated securities association for any act or omission to act constituting conduct inconsistent with just and equitable principles of trade;

(vii) Has filed (as a registrant or issuer), or was or was named as an underwriter in, any registration statement or Regulation A offering statement filed with the Commission that, within five years before such sale, was the subject of a refusal order, stop order, or order suspending the Regulation A exemption, or is, at the time of such sale, the subject of an investigation or proceeding to determine whether a stop order or suspension order should be issued; or

(viii) Is subject to a United States Postal Service false representation order entered within five years before such sale, or is, at the time of such sale, subject to a temporary restraining order or preliminary injunction with respect to conduct alleged by the United States Postal Service to constitute a scheme or device for obtaining money or property through the mail by means of false representations.

Schedule 1

Existing Warrants