Jaguar Health, Inc. Contracts & Agreements

Fourth ATM Amendment, dated November 13, 2024, to ATM Agreement by and among Jaguar Health, Inc., Ladenburg Thalmann & Co. Inc. and Lucid Capital Markets, LLC (Filed With SEC on November 13, 2024)

Third ATM Amendment, dated July 17, 2024, to ATM Agreement by and among Jaguar Health, Inc., Ladenburg Thalmann & Co. Inc. and Lucid Capital Markets, LLC (Filed With SEC on July 18, 2024)

Second Amendment to the At the Market Offering Agreement, dated May 23, 2024, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on May 23, 2024)

First Amendment to Amended and Restated License Agreement, dated March 16, 2024, by and between Napo Pharmaceuticals, Inc. and Nano Therapeutics S.p.A (Filed With SEC on May 14, 2024)

Streeterville Exchange Agreement (Filed With SEC on March 1, 2024)

Form of PIPE Warrant Exchange Agreement (Filed With SEC on March 1, 2024)

First Amendment to 200 Pine Street Office Lease, dated December 24, 2021, between Jaguar Health, Inc. and M & E, LLC (Filed With SEC on December 1, 2023)

Second Amendment to 200 Pine Street Office Lease, dated October 25, 2023, between Jaguar Health, Inc. and M & E, LLC (Filed With SEC on December 1, 2023)

Global Amendment No. 2, dated September 29, 2023, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on October 5, 2023)

Global Amendment No. 2, dated September 29, 2023, by and between Jaguar Health, Inc. and Uptown Capital, LLC (Filed With SEC on October 5, 2023)

Global Amendment, dated September 29, 2023, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on October 5, 2023)

Global Amendment No. 2, dated September 29, 2023, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on October 5, 2023)

Form of Warrant (Filed With SEC on October 5, 2023)

Exchange Agreement, dated September 29, 2023, by and between Jaguar Health, Inc. and Uptown Capital, LLC (Filed With SEC on October 5, 2023)

Binding Memorandum of Understanding, dated June 30, 2023, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc., Iliad Research and Trading, L.P., Uptown Capital, LLC and... (Filed With SEC on August 14, 2023)

Amendment No. 1 to Manufacturing and Supply Agreement, dated July 12, 2023, by and between Napo Pharmaceuticals, Inc. and Glenmark Life Sciences Limited (Filed With SEC on August 14, 2023)

Form of Exchange Agreement (Filed With SEC on July 3, 2023)

First Amendment to the Standstill Agreement, dated June 28, 2023, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc., Iliad Research and Trading, L.P., Uptown Capital,... (Filed With SEC on July 3, 2023)

Second Amendment to the Jaguar Health, Inc. New Employee Inducement Award Plan (Filed With SEC on May 19, 2023)

Form of Warrant (Filed With SEC on May 9, 2023)

Form of Securities Purchase Agreement (Filed With SEC on May 9, 2023)

Standstill Agreement (Filed With SEC on May 9, 2023)

Mutual Termination of License Agreement, dated as of January 31, 2023, by and among Jaguar Health, Inc., SynWorld Technologies Corporation, C&E Telecom, LTD, and Tao Wang (Filed With SEC on February 6, 2023)

Form of Company Stock Option Cancellation Agreement (Filed With SEC on December 30, 2022)

Securities Purchase Agreement, dated November 11, 2022, by and between Jaguar Health, Inc. and SynWorld Technologies Corporation (Filed With SEC on November 16, 2022)

Global Amendment, dated October 17, 2022, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Streeterville Capital, LLC (Filed With SEC on October 21, 2022)

Amended and Restated License and Services Agreement, dated October 11, 2022, by and among Jaguar Health, Inc., SynWorld Technologies Corporation, C&E Telecom, LTD and Tao Wang (Filed With SEC on October 14, 2022)

Royalty Interest, dated August 24, 2022, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on August 30, 2022)

Royalty Interest Purchase Agreement, dated August 24, 2022, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on August 30, 2022)

Manufacturing Services Agreement, dated June 10, 2022, by and between Napo Pharmaceuticals, Inc. and Patheon Pharmaceuticals Inc (Filed With SEC on August 24, 2022)

Securities Purchase Agreement, dated August 18, 2022, by and between Jaguar Health, Inc. and SynWorld Technologies Corporation (Filed With SEC on August 23, 2022)

First Amendment to the License and Services Agreement, dated August 18, 2022, by and between Jaguar Health, Inc. and SynWorld Technologies Corporation (Filed With SEC on August 23, 2022)

Amended and Restated License Agreement, dated July 19, 2022, by and between Napo Pharmaceuticals, Inc. and Napo Therapeutics S.p.A (Filed With SEC on July 20, 2022)

License and Services Agreement, dated June 29 2022, by and among Jaguar Health, Inc., SynWorld Technologies Corporation, C&E Telecom, LTD and Tao Wang (Filed With SEC on June 29, 2022)

Global Amendment, dated April 14, 2022, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on April 15, 2022)

Global Amendment, dated April 14, 2022, by and between Jaguar Health, Inc. and Uptown Capital, LLC (Filed With SEC on April 15, 2022)

Global Amendment, dated April 14, 2022, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on April 15, 2022)

Global Amendment, dated April 14, 2022, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Streeterville Capital, LLC (Filed With SEC on April 15, 2022)

First Amendment to the Jaguar Health, Inc. New Employee Inducement Award Plan (Filed With SEC on April 15, 2022)

First Amendment to the At the Market Offering Agreement, dated February 2, 2022, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on February 2, 2022)

At The Market Offering Agreement, dated December 10, 2021, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on December 10, 2021)

Securities Purchase Agreement, dated September 13, 2021, by and between Jaguar Health, Inc. and the investors named therein (Filed With SEC on September 17, 2021)

License Agreement, dated August 18, 2021, by and between Napo Pharmaceuticals, Inc. and Napo EU S.p.A (Filed With SEC on August 24, 2021)

Subscription Agreement, dated June 1, 2021, by and among Dragon SPAC S.p.A., Napo Pharmaceuticals, Inc. and Joshua Mailman (Filed With SEC on June 4, 2021)

Certain information marked as [****] has been excluded from this exhibit because it is both (i)not material and (ii)would be competitively harmful if publicly disclosed. OFFICE... (Filed With SEC on May 17, 2021)

CONSENT TO SUBLEASE AGREEMENT (Filed With SEC on May 17, 2021)

Certain information marked as [****] has been excluded from this exhibit because it is both (i)not material and (ii)would be competitively harmful if publicly disclosed.... (Filed With SEC on May 17, 2021)

Placement Agency Agreement, dated April 29, 2021, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on April 30, 2021)

Form of Securities Purchase Agreement (Filed With SEC on April 30, 2021)

Common Stock Purchase Warrant, dated April 7, 2021, between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on April 8, 2021)

Office Lease Agreement, dated March 25, 2021, between Jaguar Health, Inc. and M & E, LLC (Filed With SEC on April 8, 2021)

First Amendment to the Equity Purchase Agreement, dated April 7, 2021, between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on April 8, 2021)

Registration Rights Agreement, dated April 7, 2021, between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on April 8, 2021)

Master Services Agreement, dated June 24, 2019, by and among Napo Pharmaceuticals, Inc., Integrium, LLC, and POC Capital, LLC (Filed With SEC on March 31, 2021)

Master Services Agreement, dated October 5, 2020, by and between Napo Pharmaceuticals, Inc. and Integrium, LLC (Filed With SEC on March 31, 2021)

Royalty Interest, dated March 8, 2021, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on March 11, 2021)

Securities Purchase Agreement, dated March 8, 2021, by and between Jaguar Health, Inc. and Streeterville Capital, LLC (Filed With SEC on March 11, 2021)

Secured Promissory Note, dated January 19, 2021, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Streeterville Capital, LLC (Filed With SEC on January 22, 2021)

Note Purchase Agreement, dated January 19, 2021, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Streeterville Capital, LLC (Filed With SEC on January 22, 2021)

Security Agreement, dated January 19, 2021, by and between Napo Pharmaceuticals, Inc. and Streeterville Capital, LLC (Filed With SEC on January 22, 2021)

Placement Agency Agreement, dated January 13, 2021, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on January 14, 2021)

Form of Securities Purchase Agreement (Filed With SEC on January 14, 2021)

Royalty Interest, dated December 22, 2020, by and between Jaguar Health, Inc. and Irving Park Capital, LLC (Filed With SEC on December 29, 2020)

Securities Purchase Agreement, dated December 22, 2020, by and between Jaguar Health, Inc. and Irving Park Capital, LLC (Filed With SEC on December 29, 2020)

Office Sublease Agreement, dated August 31, 2020, by and between Jaguar Health, Inc. and Peacock Construction, Inc (Filed With SEC on November 16, 2020)

Consent to Sublease Agreement, dated August 31, 2020, by and among M&E, LLC, Jaguar Health, Inc., and Peacock Construction, Inc (Filed With SEC on November 16, 2020)

Manufacturing and Supply Agreement, dated September 3, 2020, by and between Glenmark Life Sciences Limited and Napo Pharmaceuticals, Inc (Filed With SEC on November 16, 2020)

Form of Pre-Funded Common Stock Purchase Warrant (Filed With SEC on October 9, 2020)

Fee Settlement Agreement, dated October 7, 2020, by and between Jaguar Health, Inc. and Atlas Sciences, LLC (Filed With SEC on October 9, 2020)

Royalty Interest, dated October 8, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on October 9, 2020)

Royalty Interest Purchase Agreement, dated October 8, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on October 9, 2020)

Exchange Agreement, dated October 8, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on October 9, 2020)

Stock Plan Agreement, dated October 6, 2020, by and between Jaguar Health, Inc. and PoC Capital, LLC (Filed With SEC on October 7, 2020)

At The Market Offering Agreement, dated October 5, 2020, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on October 5, 2020)

Global Amendment, dated September 1, 2020, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Chicago Venture Partners, L.P (Filed With SEC on September 2, 2020)

Exchange Agreement, dated September 1, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on September 2, 2020)

Stock Plan Agreement for Payment of Consulting Services, dated September 1, 2020, by and among Jaguar Health, Inc., Sagard Capital Partners Management Corp. and Sagard Capital... (Filed With SEC on September 2, 2020)

Form of Severance and Change of Control Agreement (Filed With SEC on August 13, 2020)

First Amendment to Purchase Agreement, dated June 26, 2020, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Oasis Capital, LLC (Filed With SEC on August 13, 2020)

First Amendment to Assignment Agreement, dated June 26, 2020, by and between Napo Pharmaceuticals, Inc. and Oasis Capital, LLC (Filed With SEC on August 13, 2020)

First Amendment to Royalty Interest Purchase Agreement and Related Documents, dated July 10, 2020, between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on July 14, 2020)

Jaguar Health, Inc. New Employee Inducement Award Plan (Filed With SEC on June 19, 2020)

Form of Notice of Grant of Stock Option and Stock Option Agreement under the Jaguar Health, Inc. New Employee Inducement Award Plan (Filed With SEC on June 19, 2020)

Form of Notice of Grant of Restricted Stock Units and Restricted Stock Unit Agreement under the Jaguar Health, Inc. New Employee Inducement Award Plan (Filed With SEC on June 19, 2020)

Form of Series 3 Warrant (Filed With SEC on May 22, 2020)

Form of Inducement Letter for Original Warrants (Filed With SEC on May 22, 2020)

Form of Inducement Letter for Bridge Warrants (Filed With SEC on May 22, 2020)

Purchase Agreement, dated May 12, 2020, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Oasis Capital, LLC (Filed With SEC on May 21, 2020)

Assignment Agreement, dated May 12, 2020, by and between Napo Pharmaceuticals, Inc. and Oasis Capital, LLC (Filed With SEC on May 21, 2020)

Purchase Agreement, dated April 15, 2020, by and between Napo Pharmaceuticals, Inc. and Atlas Sciences, LLC (Filed With SEC on April 16, 2020)

License Agreement, dated April 15, 2020, by and between Jaguar Health, Inc. and Atlas Sciences, LLC (Filed With SEC on April 16, 2020)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1945, as amended (Filed With SEC on April 3, 2020)

Jaguar Health, Inc. 2014 Stock Incentive Plan as Amended and Restated Effective October 1, 2019 (Filed With SEC on April 3, 2020)

Securities Purchase Agreement, dated March 23, 2020, by and between Jaguar Health, Inc. and the investors named therein (Filed With SEC on March 26, 2020)

Warrant Exercise and Preferred Stock Amendment Agreement, dated March 24, 2020, by and between Jaguar Health, Inc. and the Holder named therein (Filed With SEC on March 26, 2020)

Leak-Out Agreement, dated March 24, 2020, by and between Jaguar Health, Inc. and the Holder named therein (Filed With SEC on March 26, 2020)

Equity Purchase Agreement, dated March 24, 2020, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on March 26, 2020)

Registration Rights Agreement, dated March 24, 2020, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on March 26, 2020)

Landlord Letter of Credit Agreement, dated March 24, 2020, by and between Jaguar Health, Inc. and Charles Conte (Filed With SEC on March 26, 2020)

Royalty Interest, dated March 4, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on March 6, 2020)

Securities Purchase Agreement, dated March 4, 2020, by and between Jaguar Health, Inc. and Iliad Research and Trading, L.P (Filed With SEC on March 6, 2020)

Form of Warrant Exercise Agreement by and between Jaguar Health, Inc. and the Holder named therein (Filed With SEC on February 28, 2020)

First Amendment to the Exchange Agreement, dated January 22, 2020, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on January 27, 2020)

Form of Warrant (Filed With SEC on December 26, 2019)

Securities Purchase Agreement, dated December 20, 2019, by and between Jaguar Health, Inc. and the investors named therein (Filed With SEC on December 26, 2019)

Exchange Agreement, dated December 23, 2019, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on December 26, 2019)

Lock-Up Agreement, dated December 23, 2019, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on December 26, 2019)

Form of Pre-Funded Common Stock Purchase Warrant (Filed With SEC on November 14, 2019)

Securities Purchase Agreement, dated November 13, 2019, by and between Jaguar Health, Inc. and the purchasers named therein (Filed With SEC on November 14, 2019)

China Life Science Advisory Agreement, dated October 8, 2019, by and between Jaguar Health, Inc. and Angel Pond Capital LLC (Filed With SEC on October 22, 2019)

Promissory Note, dated October 1, 2019, between Napo Pharmaceuticals, Inc. and Michael Tempesta (Filed With SEC on October 7, 2019)

License Termination and Settlement Agreement, dated October 1, 2019, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Michael Tempesta (Filed With SEC on October 7, 2019)

Warrant Exercise Agreement, dated October 2, 2019, between Jaguar Health, Inc. and the purchaser named therein (Filed With SEC on October 3, 2019)

Amendment No. 1 to Registration Rights Agreement, dated May 30, 2019, by and between Jaguar Health, Inc. and Sagard Capital Partners, L.P (Filed With SEC on September 27, 2019)

First Amendment to Landlord Letter of Credit & Warrant Issuance Agreement, dated September 16, 2019, by and between Jaguar Health, Inc. and Pacific Capital Management, LLC (Filed With SEC on September 20, 2019)

Promotion Letter, dated September 6, 2019 (Filed With SEC on September 9, 2019)

Form of Exchange Agreement, between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on August 14, 2019)

Form of Series 1 Warrant (Filed With SEC on July 23, 2019)

Form of Series 2 Warrant (Filed With SEC on July 23, 2019)

Form of Underwriting Agreement (Filed With SEC on July 18, 2019)

Form of Series 1 Warrant to purchase shares of common stock (Filed With SEC on July 18, 2019)

Form of Series 2 Warrant to purchase shares of common stock (Filed With SEC on July 18, 2019)

Form of Leak-out Agreement (Filed With SEC on July 18, 2019)

Form of Underwriting Agreement (Filed With SEC on July 15, 2019)

Form of Series 1 Warrant to purchase shares of common stock (Filed With SEC on July 15, 2019)

Form of Series 2 Warrant to purchase shares of common stock (Filed With SEC on July 15, 2019)

Form of Warrant Agency Agreement between the Company and American Stock Transfer & Trust Company, LLC (Filed With SEC on July 15, 2019)

Form of Amendment Agreement (Filed With SEC on July 5, 2019)

Specimen Common Stock Certificate of Jaguar Health, Inc (Filed With SEC on June 6, 2019)

Secured Promissory Note, dated May 28, 2019, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Chicago Venture Partners, L.P (Filed With SEC on June 3, 2019)

Guaranty and Suretyship Agreement, dated May 28, 2019, made by Jaguar Health, Inc (Filed With SEC on June 3, 2019)

Exchange Agreement, dated May 28, 2019, by and among Jaguar Health, Inc., Napo Pharmaceuticals, Inc. and Chicago Venture Partners, L.P (Filed With SEC on June 3, 2019)

Security Agreement, dated May 28, 2019, between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on June 3, 2019)

Security Agreement, dated May 28, 2019, between Napo Pharmaceuticals, Inc. and Chicago Venture Partners, L.P (Filed With SEC on June 3, 2019)

Form of LOC Common Stock Warrant (Filed With SEC on April 4, 2019)

Letter of Credit Cancellation & Warrant Issuance Agreement, dated March 29, 2019, by and between Jaguar Health, Inc. and the letter of credit beneficiary named therein (Filed With SEC on April 4, 2019)

Common Stock Purchase Agreement, dated April 1, 2019, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on April 1, 2019)

Form of Placement Agent Warrant (Filed With SEC on March 26, 2019)

Placement Agency Agreement, dated March 24, 2019, by and between Jaguar Health, Inc. and Ladenburg Thalmann & Co. Inc (Filed With SEC on March 25, 2019)

Securities Purchase Agreement, dated March 24, 2019, by and between Jaguar Health, Inc. and the Investor (Filed With SEC on March 25, 2019)

Form of 75% Coverage Promissory Note (Filed With SEC on March 22, 2019)

Form of 125% Coverage Promissory Note (Filed With SEC on March 22, 2019)

Form of Common Stock Warrant (Filed With SEC on March 22, 2019)

Form of Securities Purchase Agreement (Filed With SEC on March 22, 2019)

Form of Registration Rights Agreement (Filed With SEC on March 22, 2019)

Common Stock Purchase Agreement, dated January 7, 2019, by and between Jaguar Health, Inc. and Oasis Capital, LLC (Filed With SEC on January 8, 2019)

Suspension, Settlement and Termination Agreement, dated December 4, 2018, by and among Napo Pharmaceuticals, Inc., Jaguar Health, Inc. and SmartPharma, LLC (Filed With SEC on December 10, 2018)

Standstill Agreement, dated October 1, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on October 5, 2018)

Form of Underwriting Agreement (Filed With SEC on October 1, 2018)

Form of Pre-Funded Warrant (Filed With SEC on October 1, 2018)

Convertible Promissory Note, dated September 11, 2018, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on September 12, 2018)

Convertible Promissory Note, dated September 11, 2018, by and between Jaguar Health, Inc. and Charles Conte (Filed With SEC on September 12, 2018)

Common Stock Warrant, dated September 11, 2018, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on September 12, 2018)

Common Stock Warrant, dated September 11, 2018, by and between Jaguar Health, Inc. and Charles Conte (Filed With SEC on September 12, 2018)

Note Purchase Agreement, dated September 11, 2018, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on September 12, 2018)

Note Purchase Agreement, dated September 11, 2018, by and between Jaguar Health, Inc. and Charles Conte (Filed With SEC on September 12, 2018)

Registration Rights Agreement, dated September 11, 2018, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on September 12, 2018)

Registration Rights Agreement, dated September 11, 2018, by and between Jaguar Health, Inc. and Charles Conte (Filed With SEC on September 12, 2018)

Common Stock Warrant, dated August 28, 2018, by and between Jaguar Health, Inc. and the holder named therein (Filed With SEC on September 4, 2018)

Office Lease Agreement, dated August 30, 2018, between Jaguar Health, Inc. and CA-Mission Street Limited Partnership (Filed With SEC on September 4, 2018)

Landlord Letter of Credit & Warrant Issuance Agreement, dated August 28, 2018, by and between Jaguar Health, Inc. and the letter of credit facilitator named therein (Filed With SEC on September 4, 2018)

Amended and Restated Security Agreement, dated July 31, 2017, by and among Napo Pharmaceuticals, Inc., Kingdon Capital Management, L.L.C., and the purchasers named therein (Filed With SEC on August 29, 2018)

Co-Promotion Agreement, dated June 28, 2018, by and between Napo Pharmaceuticals, Inc. and RedHill Biopharma, Inc (Filed With SEC on August 13, 2018)

Offer Letter, dated May 25, 2018 (Filed With SEC on June 11, 2018)

Offer Letter, dated May 25, 2018 (Filed With SEC on May 29, 2018)

Collaboration Agreement, dated December 13, 2017, by and between Jaguar Health, Inc. and Seed Mena Businessmen Services, LLC (Filed With SEC on April 9, 2018)

Secured Promissory Note, dated March 21, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 27, 2018)

Series A Preferred Stock Purchase Agreement, dated March 23, 2018, by and between Jaguar Health, Inc. and Sagard Capital Partners, L.P (Filed With SEC on March 27, 2018)

Registration Rights Agreement, dated March 23, 2018, by and between Jaguar Health, Inc. and Sagard Capital Partners, L.P (Filed With SEC on March 27, 2018)

Form of Common Stock Purchase Agreement, dated March 23, 2018, by and between Jaguar Health, Inc. and the purchasers named therein (Filed With SEC on March 27, 2018)

Management Services Agreement, dated March 23, 2018, by and between Jaguar Health, Inc. and Sagard Capital Partners Management Corp (Filed With SEC on March 27, 2018)

Securities Purchase Agreement, dated March 21, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 27, 2018)

Security Agreement, dated March 21, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 27, 2018)

Secured Promissory Note, dated February 26, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 2, 2018)

Securities Purchase Agreement, dated February 26, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 2, 2018)

Security Agreement, dated February 26, 2018, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on March 2, 2018)

Consent and Payoff Agreement, dated February 27, 2018, by and between Napo Pharmaceuticals, Inc. and the purchasers named therein (Filed With SEC on February 28, 2018)

Form of Second Amended Original Issue Discount Exchangeable Promissory Note (Filed With SEC on February 16, 2018)

Second Amendment to the Note Purchase Agreement and Notes and Payoff Agreement, dated February 16, 2018, by and among Jaguar Health, Inc. and the purchasers named therein (Filed With SEC on February 16, 2018)

Form of First Amended Original Issue Discount Exchangeable Promissory Note (Filed With SEC on January 2, 2018)

First Amendment to the Note Purchase Agreement and Notes, dated December 29, 2017, by and among Jaguar Health, Inc. and the purchasers named therein (Filed With SEC on January 2, 2018)

Secured Promissory Note, dated December 8, 2017, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on December 14, 2017)

Securities Purchase Agreement, dated December 8, 2017, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on December 14, 2017)

Security Agreement, dated December 8, 2017, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on December 14, 2017)

Share Purchase Agreement, dated November 24, 2017, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on November 24, 2017)

Common Stock Purchase Agreement, dated November 24, 2017, by and between Jaguar Health, Inc. and L2 Capital, LLC (Filed With SEC on November 24, 2017)

Share Purchase Agreement, dated July 31, 2017, by and between Jaguar Health, Inc. and Invesco Asset Management Limited (Filed With SEC on November 20, 2017)

Termination, Asset Transfer and Transition Agreement, dated September 22, 2017, by and between Napo Pharmaceuticals, Inc. and Glenmark Pharmaceuticals, Ltd (Filed With SEC on November 20, 2017)

Letter Agreement, dated October 25, 2017, by and between Jaguar Health, Inc. and Maxim Group LLC (Filed With SEC on October 26, 2017)

Underwriting Agreement, dated September 29, 2017, by and between Jaguar Health, Inc. and Maxim Group LLC (Filed With SEC on October 3, 2017)

Letter Agreement, dated September 1, 2017, by and among Napo Pharmaceuticals, Inc., MEF I, L.P. and Riverside Merchant Partners (Filed With SEC on September 14, 2017)

Letter Agreement, dated August 31, 2017, by and among Napo Pharmaceuticals, Inc., M. Kingdon Offshore Master Fund L.P., Kingdon Family Partnership, L.P. and Kingdon Credit Master... (Filed With SEC on September 14, 2017)

Letter Agreement, dated August 28, 2017, by and among Napo Pharmaceuticals, Inc., Dorsar Investment Company, Alco Investment Company and Two Daughters LLC (Filed With SEC on September 14, 2017)

Letter Agreement, dated September 1, 2017, by and between Napo Pharmaceuticals, Inc. and Boies Schiller Flexner LLP (Filed With SEC on September 14, 2017)

Letter Agreement, dated August 30, 2017, by and between Jaguar Health, Inc. and Chicago Venture Partners, L.P (Filed With SEC on September 14, 2017)

[JAGUAR LETTERHEAD] (Filed With SEC on July 31, 2017)

SECURED CONVERTIBLE PROMISSORY NOTE (Filed With SEC on July 3, 2017)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on July 3, 2017)

SUBORDINATION AGREEMENT AND RIGHT TO PURCHASE DEBT (Filed With SEC on July 3, 2017)

SECURITY AGREEMENT (Filed With SEC on July 3, 2017)

EMPLOYEE LEASING AND OVERHEAD ALLOCATION AGREEMENT (Filed With SEC on May 15, 2017)

AMENDMENT NO. 1 TO EMPLOYEE LEASING AND OVERHEAD ALLOCATION AGREEMENT (Filed With SEC on May 15, 2017)

NOTE PURCHASE AGREEMENT (Filed With SEC on April 18, 2017)

FORM OF EXCHANGEABLE PROMISSORY NOTE (Filed With SEC on April 18, 2017)

AMENDED AND RESTATED NOTE PURCHASE AGREEMENT (Filed With SEC on April 18, 2017)

FORM OF CONVERTIBLE PROMISSORY NOTE (Filed With SEC on April 18, 2017)

LIMITED SUBORDINATION AGREEMENT (Filed With SEC on April 18, 2017)

SECURITY AGREEMENT (Filed With SEC on April 18, 2017)

SETTLEMENT AND DISCOUNTED PAYOFF AGREEMENT (Filed With SEC on April 18, 2017)

DEBT AND WARRANT SETTLEMENT AGREEMENT (Filed With SEC on April 18, 2017)

DEBT SETTLEMENT AGREEMENT (Filed With SEC on April 18, 2017)

FORM OF ESCROW AGREEMENT (Filed With SEC on April 18, 2017)

FORM OF RESTRICTED STOCK UNIT INDEMNIFICATION AND FORFEITURE AGREEMENT (Filed With SEC on April 18, 2017)

INVESTOR RIGHTS AGREEMENT by and between JAGUAR ANIMAL HEALTH, INC. and NANTUCKET INVESTMENTS LIMITED Dated as of March 31, 2017 (Filed With SEC on March 31, 2017)

*** TEXT OMITTED AND SUBMITTED PURSUANT TO CONFIDENTIAL TREATMENT REQUEST DISTRIBUTION AGREEMENT (Filed With SEC on February 15, 2017)

*** TEXT OMITTED AND SUBMITTED PURSUANT TO CONFIDENTIAL TREATMENT REQUEST LICENSE, DEVELOPMENT, CO-PROMOTION AND COMMERCIALIZATION AGREEMENT BY AND BETWEEN JAGUAR ANIMAL HEALTH,... (Filed With SEC on February 15, 2017)

[Jaguar ANIMAL HEALTH letterhead] (Filed With SEC on February 15, 2017)

BINDING AGREEMENT OF TERMS FOR JAGUAR ANIMAL HEALTH, INC. ACQUISITION OF NAPO PHARMACEUTICALS, INC. FEBRUARY 8, 2017 (Filed With SEC on February 9, 2017)

COMMON STOCK PURCHASE WARRANT JAGUAR ANIMAL HEALTH, INC. (Filed With SEC on November 29, 2016)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on November 29, 2016)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on November 29, 2016)

*** TEXT OMITTED AND SUBMITTED SEPARATELY PURSUANT TO CONFIDENTIAL TREATMENT REQUEST JAGUAR ANIMAL HEALTH, INC. AND INTEGRATED ANIMAL NUTRITION AND HEALTH INC. (Filed With SEC on November 14, 2016)

[Jaguar ANIMAL HEALTH letterhead] (Filed With SEC on November 14, 2016)

RE: PROPOSED MERGER BETWEEN NAIROBI PHARMACEUTICALS INC (NAIROBI) AND JOHANNESBURG ANIMAL HEALTH INC (JOHANNESBURG OR JOBURG) (Filed With SEC on October 6, 2016)

JAGUAR ANIMAL HEALTH, INC. 2014 STOCK INCENTIVE PLAN AS AMENDED AND RESTATED EFFECTIVE JUNE 14, 2016 (Filed With SEC on June 20, 2016)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on June 9, 2016)

COMMON STOCK PURCHASE AGREEMENT (Filed With SEC on June 9, 2016)

Jaguar Animal Health, Inc. 201 Mission Street 23rdfloor San Francisco, CA 94105 Tel: +1 ###-###-#### Fax: +1 ###-###-#### www.jaguaranimalhealth.com (Filed With SEC on May 3, 2016)

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT AND WAIVER (Filed With SEC on April 27, 2016)

FORM OF UNDERWRITING AGREEMENT between JAGUAR ANIMAL HEALTH, INC. and AEGIS CAPITAL CORP., as Representative of the Several Underwriters (Filed With SEC on January 26, 2016)

Patheon Pharmaceuticals Inc. (Patheon) Jaguar Animal Health (Client) By: /s/ Francis P. McCone By: /s/ Steven R. King Name: Francis P. McCone Name: Steven R. King Title: Secretary... (Filed With SEC on January 7, 2016)

MANUFACTURE AND SUPPLY AGREEMENT (Filed With SEC on November 13, 2015)

LOAN AND SECURITY AGREEMENT (Filed With SEC on August 20, 2015)

SUBLEASE AGREEMENT (Filed With SEC on June 23, 2015)

CONSENT TO SUBLEASE (Filed With SEC on June 23, 2015)

FORM OF UNDERWRITING AGREEMENT between JAGUAR ANIMAL HEALTH, INC. and AEGIS CAPITAL CORP., as Representative of the Several Underwriters (Filed With SEC on April 17, 2015)

AMENDED AND RESTATED STANDBY BRIDGE FINANCING AGREEMENT Dated as of December 3, 2014 By and Among GPB LIFE SCIENCE HOLDINGS LLC (CO-LENDER) 31 GROUP LLC (CO-LENDER) and JAGUAR... (Filed With SEC on April 17, 2015)

JAGUAR ANIMAL HEALTH, INC. FORM OF EXCHANGE WARRANT TO PURCHASE COMMON STOCK (Filed With SEC on April 17, 2015)

Form of Representatives Warrant Agreement (Filed With SEC on April 17, 2015)

FORM OF JAGUAR ANIMAL HEALTH, INC. JUNE/2014 CONVERTIBLE NOTE EXERCISE AMENDMENT (Filed With SEC on April 17, 2015)

FORM OF JAGUAR ANIMAL HEALTH, INC. WARRANT & NOTE EXERCISE AMENDMENT (Filed With SEC on April 17, 2015)

FORM OF JAGUAR ANIMAL HEALTH, INC. NOTE EXERCISE AMENDMENT AND CONVERSION AGREEMENT (Filed With SEC on April 17, 2015)

CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT (Filed With SEC on April 17, 2015)

JAGUAR ANIMAL HEALTH, INC. CONVERTIBLE PROMISSORY NOTE (Filed With SEC on April 17, 2015)

JAGUAR ANIMAL HEALTH, INC. COMMON STOCK WARRANT (Filed With SEC on April 17, 2015)

FORM OF JAGUAR ANIMAL HEALTH, INC. WARRANT EXERCISE AMENDMENT (Filed With SEC on April 17, 2015)

JAGUAR ANIMAL HEALTH, INC. FORM OF AMENDED AND RESTATED EXCHANGE WARRANT TO PURCHASE COMMON STOCK (Filed With SEC on April 17, 2015)

JAGUAR ANIMAL HEALTH, INC. EXCHANGE WARRANT TO PURCHASE COMMON STOCK (Filed With SEC on March 20, 2015)

AMENDMENT NO. 1 TO AMENDED AND RESTATED LICENSE AGREEMENT (Filed With SEC on March 20, 2015)

FORM OF CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT (Filed With SEC on March 20, 2015)

JAGUAR ANIMAL HEALTH, INC. FORM OF CONVERTIBLE PROMISSORY NOTE (Filed With SEC on March 20, 2015)

JAGUAR ANIMAL HEALTH, INC. FORM OF COMMON STOCK WARRANT (Filed With SEC on March 20, 2015)

Jaguar Animal Health, Inc. 185 Berry Street, Suite 1300 San Francisco, CA 94107 Tel: +1 ###-###-#### Fax: +1 ###-###-#### www.jaguaranimalhealth.com (Filed With SEC on March 20, 2015)

JAGUAR ANIMAL HEALTH, INC. 2014 STOCK INCENTIVE PLAN (Filed With SEC on October 31, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF WARRANT TO PURCHASE COMMON STOCK (Filed With SEC on October 31, 2014)

Common Stock JAGUAR ANIMAL HEALTH, INC. UNDERWRITING AGREEMENT (Filed With SEC on October 28, 2014)

Jaguar Animal Health, Inc. 185 Berry Street, Suite 1300 San Francisco, CA 94107 Tel: +1 ###-###-#### Fax: +1 ###-###-#### www.jaguaranimalhealth.com (Filed With SEC on October 10, 2014)

NAPO PHARMACEUTICALS, INC. 185 Berry Street, Suite 1300 San Francisco, CA 94107 (Filed With SEC on October 10, 2014)

LINE OF CREDIT LOAN AGREEMENT (Filed With SEC on September 9, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF COMMON STOCK WARRANT (Filed With SEC on September 9, 2014)

INVESTORS RIGHTS AGREEMENT (Filed With SEC on August 27, 2014)

FORM OF INDEMNIFICATION AGREEMENT (Filed With SEC on August 27, 2014)

Jaguar Animal Health, Inc. 2013 Equity Incentive Plan November 1, 2013 (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF NOTICE OF GRANT OF STOCK OPTION (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF NOTICE OF GRANT OF RESTRICTED STOCK UNITS (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. 2014 STOCK INCENTIVE PLAN (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF NOTICE OF GRANT OF STOCK OPTION (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF NOTICE OF GRANT OF RESTRICTED STOCK (Filed With SEC on August 27, 2014)

JAGUAR ANIMAL HEALTH, INC. FORM OF NOTICE OF GRANT OF RESTRICTED STOCK UNITS (Filed With SEC on August 27, 2014)

EXHIBIT A TO THE OFFER LETTER EMPLOYMENT, CONFIDENTIAL INFORMATION, INVENTION ASSIGNMENT AND ARBITRATION AGREEMENT (Filed With SEC on August 27, 2014)

Jaguar Animal Health, Inc. 185 Berry Street, Suite 1300 San Francisco, CA 94107 Tel: +1 ###-###-#### Fax: +1 ###-###-#### www.jaguaranimalhealth.com (Filed With SEC on August 27, 2014)

EXHIBIT A TO THE OFFER LETTER EMPLOYMENT, CONFIDENTIAL INFORMATION, INVENTION ASSIGNMENT AND ARBITRATION AGREEMENT (Filed With SEC on August 27, 2014)

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