Letter Agreement between the Company and Ronald E. Bruehlman, effective on August 1, 2020

/s/ Trudy Stein

Name: Ron Bruehlman

Annual Incentive Target: 100% of your annual base salary. Your manager will communicate performance parameters at a later date. Incentive payouts are not guaranteed and are prorated based on start date and time worked. Your start date must occur on or before September 30 to be eligible to participate in an incentive plan for the year.

Long-Term Incentive Award: As a part of your new hire offer, you have been nominated for a one­ time Restricted Stock ( Unit award (the “One-Time RSU”) with a nominal value of $2,700,000 to be effective August 3, 2020 (the “Grant Date”) subject to final approval by the Leadership Development and Compensation Committee (the “Committee”) of the Board of Directors of IQVIA Holdings Inc.

IQVIA will determine the number of One-Time RSUs by dividing the nominal value of $2,700,000 by the closing price of a share of IQVIA common stock as of the Grant Date. An RSU is the promise of a share of stock on a future date (the “Vesting Date”). It is “restricted” because until it vests, you cannot sell it and you have no voting rights. It is a “unit” because the share under1ying the unit isn't transferred to you until the Vesting Date. The One-Time RSUs will vest in equal installments on each of the first three anniversaries of the Grant Date. If you leave our employment for any reason, you will forfeit any One-Time RSUs that are unvested at that time.

One-Time RSUs approved by the Committee will be subject to the various terms and conditions of the IQVIA Holdings Inc. 2017 Incentive and Stock Award Plan (the “Plan”) and the grant agreement, including provisions regarding vesting and forfeiture.

Your One-Time RSU is contingent upon proper execution of a Confidentiality and Restrictive Covenant Agreement (CRCA) and Work Product Assignment Agreement (WPAA) relating to the protection of IQVIA intellectual property, including confidentiality, ownership, non-competition and non-solicitation. These documents will be provided to you separately.

    Vacation Days:        Discretionary Time-off

    Company Holidays:    10 Days

This offer of employment with IQVIA™ is contingent upon (a) receipt of acceptable references and credential qualifications; (b) having no existing restrictions which would prohibit you from accepting this offer or, by working for IQVIA, would infringe the rights of others; (c) your signing and returning the attached Confidentiality & Policy Agreement as well as the Third Party Confidential Information Notice; and (d) receipt of proof of your eligibility to work in the United States as required by the Immigration

Reform and Control Act of 1986. You will need to bring certain documents on your first day of employment (by law, no later than three business days from your start date). Please refer to the enclosed list of acceptable documents for Employment Eligibility Verification.

This offer letter shall not be construed as constituting a contract for employment, or otherwise set forth a length of employment. You are an employee at-will, which means that either you or IQVIA may end the employment relationship without cause or notice.

Upon your start date, any agreement(s) between you and the company with regard to your current role as a senior advisor to the CEO will terminate and will no longer be in force.

/s/ Trudy Stein