Amendment to Development and Marketing Agreement between Boehringer Ingelheim International GmbH and InterMune, Inc.

Summary

Boehringer Ingelheim International GmbH and InterMune, Inc. have agreed to amend their existing Development and Marketing Agreement dated March 23, 2001. The amendment expands the scope of the agreement to include non-Hodgkin's Lymphoma (NHL) as a covered field and indication, and adds a new clinical protocol (GINHL-001) to the agreement. Both parties have accepted these changes by signing this letter, which serves as a formal amendment to the original contract.

EX-10.54 11 a2082633zex-10_54.htm EXHIBIT 10.54

EXHIBIT 10.54

[BOEHRINGER
INGELHEIM LOGO]

Boehringer Ingelheim International GmbH - 55216 Ingelheim am Rhein
InterMune Pharmaceuticals
3280 Bayshore Blvd
Brisbane, CA 94005
U.S.A.
  Boehringer Ingelheim
International GmbH

 

 

1 July 2002

Development and Marketing Agreement dated March 23, 2001
(Agreement)

 

Our reference
CD Dr.Mi-mw

Dear Sirs

 

Dr. David Mitchard
Phone +49/61 32/77-34 08
Fax +49/61 32/77-35 83
E-Mail ***@***

Words and expressions defined or interpreted in the Agreement shall have the same meanings and interpretations when used in this letter.
 
We propose the following changes to the Agreement:

 

Binger Strasse 173
55216 Ingelheim am Rhein
Germany
Phone +49/61 32/77-0
Fax +49/61 32/72-0
www.boehringer-ingelheim.com
1.10
The definition Field is extended to include non-Hodgkin's Lymphoma (NHL).

1.22
The definition New Indications is extended to include NHL.

1.25
The definition Protocols is extended to include the clinical protocol
entitled

    "GINHL-001"

    which InterMune sent to BII with a letter dated May 30, 2002.

If you agree with the above, please signify your acceptance by signing and
returning one original of this letter.

Yours faithfully
BOEHRINGER INGELHEIM
INTERNATIONAL GmbH
ppa.
  
/s/ Dr. Mitchard Jesse
Dr. Mitchard Jesse
  Accepted for and on behalf of
InterMune, Inc.
  
/s/ John J. Wulf
John J. Wulf
by: Sr. V.P. of Corporate Development
Date: July 9, 2002
  Board of Managing Directors
Prof. Dr Dr h.c. Rolf Krebs
(Chairman)
Dr Alessandro Banchi
Dr Dr Andreas Barner
Dr Hans-Jürgen Leuchs
Prof. Dr Marbod Muff
 
Seat Ingelheim am Rhein
Commercial Register
Bingen HR B 1063
 
Deutsche Bank AG
BLZ 550 700 40
Account No. 0122 580
Swift: DEUTDE5M