INOVIO PHARMACEUTICALS, INC. Contracts & Agreements

Underwriting Agreement, dated December 12, 2024, by and among Inovio Pharmaceuticals, Inc., Oppenheimer & Co. Inc. and Citizens JMP Securities LLC (Filed With SEC on December 16, 2024)

Form of Warrant (Filed With SEC on December 16, 2024)

Equity Distribution Agreement, dated August 13, 2024, by and between Inovio Pharmaceuticals, Inc. and Oppenheimer & Co. Inc (Filed With SEC on August 13, 2024)

Underwriting Agreement, dated April 15, 2024, by and among Inovio Pharmaceuticals, Inc., Oppenheimer & Co. Inc. and Citizens JMP Securities, LLC (Filed With SEC on April 17, 2024)

Form of Pre-Funded Warrant (Filed With SEC on April 17, 2024)

First Amendment to the Amended and Restated License and Collaboration Agreement, dated June 14, 2023, by and between Inovio Pharmaceuticals, Inc. and Beijing Apollo Saturn... (Filed With SEC on March 6, 2024)

Inovio Pharmaceuticals, Inc. Severance Plan and Summary Plan Description (Filed With SEC on March 6, 2024)

Participation Agreement under Severance Plan for Jacqueline Shea (Filed With SEC on March 6, 2024)

Participation Agreement under Severance Plan for Laurent Humeau (Filed With SEC on March 6, 2024)

Participation Agreement under Severance Plan for Michael Sumner (Filed With SEC on March 6, 2024)

Form of Option Grant Package under 2023 Omnibus Incentive Plan (Filed With SEC on August 9, 2023)

Form of RSU Grant Package under 2023 Omnibus Incentive Plan (Filed With SEC on August 9, 2023)

Inovio Pharmaceuticals, Inc. 2023 Omnibus Incentive Plan (Filed With SEC on May 18, 2023)

Separation Agreement, dated as of May 10, 2022, by and between the registrant and J. Joseph Kim (Filed With SEC on August 9, 2022)

ATM Equity OfferingSM Sales Agreement dated November 9, 2021 by and among Inovio Pharmaceuticals, Inc., BofA Securities, Inc., RBC Capital Markets, LLC and Oppenheimer & Co. Inc (Filed With SEC on November 9, 2021)

Amended and Restated Collaboration and License Agreement dated June 7, 2021, by and between Inovio Pharmaceuticals, Inc. and Advaccine Biopharmaceuticals Suzhou Co., Ltd (Filed With SEC on August 9, 2021)

Collaboration and License Agreement dated December 31, 2020 between Inovio Pharmaceuticals, Inc. and Advaccine Biopharmaceuticals Suzhou Co., Ltd (Filed With SEC on March 1, 2021)

Underwriting Agreement, dated January 20, 2021, by and among the Company and the Representatives of the several Underwriters named therein (Filed With SEC on January 22, 2021)

Other Transaction Authority For Prototype Agreement dated June 22, 2020 between Inovio Pharmaceuticals, Inc. and Natick Contracting Division (Filed With SEC on August 10, 2020)

Award Agreement dated June 18, 2020 between Inovio Pharmaceuticals, Inc. and Natick Contracting Division (Filed With SEC on August 10, 2020)

At-The-Market Equity Offering Sales Agreement dated April 3, 2020 between Inovio Pharmaceuticals, Inc. and Stifel, Nicolaus & Company, Incorporated (Filed With SEC on April 3, 2020)

Description of the Registrants Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended (Filed With SEC on March 12, 2020)

Employment Agreement dated March 8, 2019 between Inovio Pharmaceuticals, Inc. and Jacqueline E. Shea (Filed With SEC on March 12, 2020)

Employment Agreement dated as of March 4, 2019 between Inovio Pharmaceuticals, Inc. and Laurent M. Humeau (Filed With SEC on March 12, 2020)

Amendment No. 2 to the At-The-Market Equity Offering Sales Agreement dated March 9, 2020 between Inovio Pharmaceuticals, Inc. and Stifel, Nicolaus & Company, Incorporated (Filed With SEC on March 9, 2020)

Amendment No. 1 to the At-The-Market Equity Offering Sales Agreement dated February 7, 2020 between Inovio Pharmaceuticals, Inc. and Stifel, Nicolaus & Company, Incorporated (Filed With SEC on February 7, 2020)

Convertible Bonds Subscription Agreement, dated December 26, 2019, by and between the Company and the Purchaser (Filed With SEC on January 2, 2020)

Registration Rights Agreement, dated December 26, 2019, by and between the Company and the Purchaser (Filed With SEC on January 2, 2020)

Convertible Bonds Subscription Agreement, dated July 31, 2019, by and among the Company and the Purchasers (Filed With SEC on August 6, 2019)

Inovio Pharmaceuticals, Inc. 2016 Omnibus Incentive Plan, as amended (Filed With SEC on May 10, 2019)

Separation Agreement dated March 26, 2019 by and between Inovio Pharmaceuticals, Inc. and Dr. Mark Bagarazzi (Filed With SEC on May 9, 2019)

Consulting Agreement dated February 21, 2019 by and between Inovio Pharmaceuticals, Inc. and Dr. Niranjan Sardesai (Filed With SEC on March 12, 2019)

Indenture, dated as of February 19, 2019, by and between the Company and U.S. Bank National Association, as trustee (Filed With SEC on February 20, 2019)

At-the-Market Equity Offering Sales Agreement dated May 25, 2018 between Inovio Pharmaceuticals, Inc. and Stifel, Nicolaus & Company, Incorporated (Filed With SEC on May 25, 2018)

Amended and Restated License and Collaboration Agreement, dated December 29, 2017, by and between Inovio Pharmaceuticals, Inc. and Beijing Apollo Saturn Biological Technology... (Filed With SEC on March 14, 2018)

Second Amendment to the Lease Agreement dated June 22, 2017 between Brandywine Operating Partnership, L.P. and Inovio Pharmaceuticals, Inc (Filed With SEC on August 8, 2017)

Sublease dated June 21, 2017 between Accolade, Inc. and Inovio Pharmaceuticals, Inc (Filed With SEC on August 8, 2017)

12,500,000 Shares INOVIO PHARMACEUTICALS, INC. Common Stock UNDERWRITING AGREEMENT (Filed With SEC on July 20, 2017)

INOVIO PHARMACEUTICALS, INC. 2016 OMNIBUS INCENTIVE PLAN NOTICE OF GRANT OF RESTRICTED STOCK UNITS (Filed With SEC on March 15, 2017)

NOTICE OF GRANT OF INCENTIVE STOCK OPTION AWARD INOVIO PHARMACEUTICALS, INC. 2016 OMNIBUS INCENTIVE PLAN (Filed With SEC on March 15, 2017)

NOTICE OF GRANT OF NON-QUALIFIED STOCK OPTION AWARD INOVIO PHARMACEUTICALS, INC. 2016 OMNIBUS INCENTIVE PLAN (Filed With SEC on March 15, 2017)

GENEOS THERAPEUTICS, INC. 2016 EQUITY INCENTIVE PLAN (Filed With SEC on November 9, 2016)

FORM OF INCENTIVE STOCK OPTION AGREEMENT (Filed With SEC on November 9, 2016)

FORM OF NONQUALIFIED STOCK OPTION AGREEMENT (Filed With SEC on November 9, 2016)

NONQUALIFIED STOCK OPTION AGREEMENT (Filed With SEC on November 9, 2016)

GENEOS THERAPEUTICS, INC. FORM OF RESTRICTED STOCK AGREEMENT (Filed With SEC on November 9, 2016)

INOVIO PHARMACEUTICALS, INC. Common Stock ($0.001 par valueper share) AT-THE-MARKET EQUITY OFFERING SALES AGREEMENT (Filed With SEC on June 17, 2016)

COLLABORATIVE RESEARCH AGREEMENT (Filed With SEC on May 9, 2016)

INOVIO BIOMEDICAL CORPORATION 2007 OMNIBUS INCENTIVE PLAN As Amended Adopted by the Board of Directors: March31, 2007 Approved by Stockholders: May4, 2007 As Amended by the Board... (Filed With SEC on March 14, 2016)

DNA CANCER VACCINE COLLABORATION AND LICENSE AGREEMENT (Filed With SEC on November 9, 2015)

9,500,000 Shares INOVIO PHARMACEUTICALS, INC. Common Stock PURCHASE AGREEMENT (Filed With SEC on April 30, 2015)

INOVIO BIOMEDICAL CORPORATION 2007 OMNIBUS INCENTIVE PLAN As Amended Adopted by the Board of Directors: March31, 2007 Approved by Stockholders: May4, 2007 As Amended by the Board... (Filed With SEC on March 16, 2015)

SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on November 10, 2014)

LEASE (Filed With SEC on March 17, 2014)

18,966,000 Shares1 INOVIO PHARMACEUTICALS, INC. Common Stock PURCHASE AGREEMENT (Filed With SEC on February 27, 2014)

TERMINATION OF VOTING TRUST AGREEMENT (Filed With SEC on November 12, 2013)

Collaboration, Option and License Agreement (Filed With SEC on September 12, 2013)

LEASE by and between BMR-WATERIDGE LP, a Delaware limited partnership and INOVIO PHARMACEUTICALS, INC., a Delaware corporation LEASE (Filed With SEC on May 10, 2013)

INOVIO BIOMEDICAL CORPORATION 2007 OMNIBUS INCENTIVE PLAN As Amended Adopted by the Board of Directors: March31, 2007 Approved by Stockholders: May4, 2007 As Amended by the Board... (Filed With SEC on March 18, 2013)

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on March 18, 2013)

INOVIO PHARMACEUTICALS, INC. 27,377,266 Shares of Common Stock and Warrants to Purchase 13,688,633 Shares of Common Stock UNDERWRITINGAGREEMENT (Filed With SEC on March 7, 2013)

INOVIO PHARMACEUTICALS, INC. WARRANT TOPURCHASE COMMON STOCK (Filed With SEC on March 7, 2013)

INOVIO PHARMACEUTICALS, INC. $25,000,000 SALES AGREEMENT (Filed With SEC on June 1, 2012)

EMPLOYMENT AGREEMENT (Filed With SEC on March 15, 2012)

6,737,247 Units INOVIO PHARMACEUTICALS, INC. UNDERWRITING AGREEMENT (Filed With SEC on December 1, 2011)

INOVIO PHARMACEUTICALS, INC. WARRANT TOPURCHASE COMMON STOCK (Filed With SEC on December 1, 2011)

COLLABORATIVE DEVELOPMENT AND LICENSE AGREEMENT BETWEEN VGX INTERNATIONAL, INC. (VGXI) AND INOVIO PHARMACEUTICALS, INC. (INO) (Filed With SEC on November 7, 2011)

EMPLOYMENT AGREEMENT (Filed With SEC on March 16, 2011)

21,130,400 Units (Filed With SEC on January 24, 2011)

INOVIO PHARMACEUTICALS, INC. (Filed With SEC on January 24, 2011)

INOVIOBIOMEDICAL CORPORATION 2007OMNIBUS INCENTIVE PLAN As Amended Adopted bythe Board of Directors: March 31, 2007 Approved byStockholders: May 4, 2007 As Amendedby the Board of... (Filed With SEC on November 13, 2009)

AMENDED AND RESTATED EMPLOYMENT AGREEMENT (Filed With SEC on October 6, 2009)

INDEMNIFICATION AGREEMENT (Filed With SEC on August 19, 2009)

Common Stock Greenshoe Warrant INOVIO BIOMEDICAL CORPORATION (Filed With SEC on July 30, 2009)

SECURITIESPURCHASE AGREEMENT (Filed With SEC on July 30, 2009)

INOVIO BIOMEDICAL CORPORATION VOTING TRUST AGREEMENT (Filed With SEC on June 2, 2009)

INOVIO BIOMEDICAL CORPORATION AMENDED AND RESTATED 2000 STOCK OPTION PLAN (as amended by the Board of Directors through July 2, 2008 with approvals by stockholders through May 29,... (Filed With SEC on June 2, 2009)

AMENDMENT NO. 1 TO AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER (Filed With SEC on March 31, 2009)

ADDENDUM TO CREDIT LINE ACCOUNT APPLICATION AND AGREEMENT (Filed With SEC on December 23, 2008)

ADDENDUM TO EMPLOYMENTAGREEMENT (Filed With SEC on July 8, 2008)

CONSULTINGAGREEMENT (Filed With SEC on May 7, 2008)

Vincent Lum, Managing Partner (Filed With SEC on August 6, 2007)

COMMON STOCKPURCHASE WARRANT To Purchase [ ] Sharesof Common Stock of INOVIO BIOMEDICAL CORPORATION (Filed With SEC on August 6, 2007)

SECURITIESPURCHASE AGREEMENT (Filed With SEC on May 16, 2007)

COMMON STOCKPURCHASE WARRANT To Purchase [ ]Shares of Common Stock of INOVIO BIOMEDICALCORPORATION (Filed With SEC on March 16, 2007)

LICENSE AGREEMENT by and between INOVIO BIOMEDICAL CORPORATION and INOVIO ASIA PTE LTD. September 15, 2006 (Filed With SEC on November 9, 2006)

SECURITIES PURCHASE AND EXCHANGEAGREEMENT (Filed With SEC on November 9, 2006)

REGISTRATIONRIGHTS AGREEMENT (Filed With SEC on November 9, 2006)

AMENDMENT TOSECURITIES PURCHASE AGREEMENT (Filed With SEC on October 16, 2006)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on September 20, 2006)

COMMON STOCKPURCHASE WARRANT To Purchase [ ] Sharesof Common Stock of INOVIO BIOMEDICALCORPORATION (Filed With SEC on September 20, 2006)

OPTION EXERCISEAND LICENSE AGREEMENT (Filed With SEC on June 30, 2006)

Exhibit 4.1 REGISTRATION RIGHTS AGREEMENT (Filed With SEC on January 31, 2005)

STOCK PURCHASE AGREEMENT by and among GENETRONICS BIOMEDICAL CORPORATION, a Delaware corporation, INOVIO AS, a Norway corporation, and the shareholders of INOVIO AS. Dated January... (Filed With SEC on January 31, 2005)

COMMON STOCK PURCHASE WARRANT To Purchase __ Shares of Common Stock of GENETRONICS BIOMEDICAL CORPORATION (Filed With SEC on January 13, 2005)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on January 13, 2005)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on January 13, 2005)

PROMISSORY NOTE (Filed With SEC on January 13, 2005)

ESCROW AGREEMENT (Filed With SEC on January 13, 2005)

[Confidential Portions Omitted] NON-EXCLUSIVE LICENSE AND RESEARCH COLLABORATION AGREEMENT by and between MERCK & CO., INC. and GENETRONICSBIOMEDICAL CORPORATION and... (Filed With SEC on August 13, 2004)

Part I. Financial Information (Filed With SEC on August 14, 2002)

Part I. Financial Information (Filed With SEC on May 15, 2002)

Nine Months (Filed With SEC on April 1, 2002)

Part I. Financial Information (Filed With SEC on November 16, 2001)

Part I. Financial Information (Filed With SEC on August 9, 2001)

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INOVIO PHARMACEUTICALS, INC. Contracts & Agreements