Homology Medicines, Inc. Contracts & Agreements

Subscription Agreement, dated November 16, 2023, by and among Q32 Bio Operations Inc. (formerly Q32 Bio Inc.) and certain parties thereto (Filed With SEC on March 27, 2024)

Registration Rights Agreement, dated March 25, 2024, by and among Q32 Bio Operations Inc. (formerly Q32 Bio Inc.) and certain parties thereto (Filed With SEC on March 27, 2024)

Form of Lock-Up Agreement (Filed With SEC on March 27, 2024)

Contingent Value Rights Agreement dated March 23, 2024, by and between Homology Medicines Inc. and Equiniti Trust Company, LLC (Filed With SEC on March 27, 2024)

Consent and Eighth Amendment to Loan and Security Agreement, by and between Q32 Bio, Inc. and Silicon Valley Bank, a division of First-Citizens Bank & Trust Company, dated March... (Filed With SEC on March 27, 2024)

Form of Indemnification Agreement for Officers of Q32 Bio Inc (Filed With SEC on March 27, 2024)

Form of Indemnification Agreement for Directors of Q32 Bio Inc (Filed With SEC on March 27, 2024)

Q32 Bio Inc. 2017 Stock Incentive Plan, and form of award agreements thereunder (Filed With SEC on March 27, 2024)

Q32 Bio Inc. 2024 Stock Option and Incentive Plan, and form of award agreements thereunder (Filed With SEC on March 27, 2024)

Q32 Bio Inc. 2024 Employee Stock Purchase Plan (Filed With SEC on March 27, 2024)

Q32 Bio Inc. Non-Employee Director Compensation Policy (Filed With SEC on March 27, 2024)

Q32 Bio Inc. Senior Executive Cash Incentive Bonus Plan (Filed With SEC on March 27, 2024)

Q32 Bio Inc. Warrant to Purchase Common Stock dated December 11, 2020 (Filed With SEC on March 27, 2024)

Q32 Bio Inc. Warrant to Purchase Common Stock dated July 12, 2023 (Filed With SEC on March 27, 2024)

Employment Agreement between Q32 Bio Inc. and Jodie Morrison, dated March 25, 2024 (Filed With SEC on March 27, 2024)

Employment Agreement between Q32 Bio Inc. and Lee Kalowski, dated March 25, 2024 (Filed With SEC on March 27, 2024)

Employment Agreement between Q32 Bio Inc. and Jason Campagna, dated March 25, 2024 (Filed With SEC on March 27, 2024)

Employment Agreement between Q32 Bio Inc. and Shelia Violette, dated March 25, 2024 (Filed With SEC on March 27, 2024)

Description of Securities (Filed With SEC on March 13, 2024)

Agreement and Plan of Merger, dated as of November 16, 2023, by and among Homology Medicines, Inc., Kenobi Merger Sub, Inc., and Q32 Bio Inc (Filed With SEC on December 18, 2023)

Form of Support Agreement by and between Homology Medicines, Inc. and certain stockholders of Q32 Bio Inc (Filed With SEC on December 18, 2023)

Form of Support Agreement by and between Q32 Bio Inc. and certain stockholders of Homology Medicines, Inc (Filed With SEC on December 18, 2023)

Form of CVR Agreement (Filed With SEC on December 18, 2023)

Amended and Restated Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and Paul Alloway, Ph.D (Filed With SEC on December 18, 2023)

Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and Charles Michaud, Jr (Filed With SEC on December 18, 2023)

Consulting Agreement, dated November 17, 2023, by and between Homology Medicines, Inc. and W. Bradford Smith (Filed With SEC on December 18, 2023)

Asset Purchase Agreement, dated August 12, 2022, by and between Q32 Bio Inc. and Horizon Therapeutics Ireland DAC (Filed With SEC on December 18, 2023)

Collaboration and Option Agreement, dated August 12, 2022, by and between Q32 Bio Inc. and Horizon Therapeutics Ireland DAC (Filed With SEC on December 18, 2023)

Termination Agreement, dated November 10, 2023, between Q32 Bio Inc. and Horizon Therapeutics DAC (Filed With SEC on December 18, 2023)

Exclusive License Agreement, dated August 9, 2017, between Q32 Bio Inc. and The Regents of the University of Colorado (Filed With SEC on December 18, 2023)

First Amendment to the Exclusive License Agreement, dated February 8, 2017, between Q32 Bio Inc. and The Regents of the University of Colorado (Filed With SEC on December 18, 2023)

Second Amendment to the Exclusive License Agreement, dated September 27, 2018, between Q32 Bio Inc. and The Regents of the University of Colorado (Filed With SEC on December 18, 2023)

Third Amendment to the Exclusive License Agreement, dated April 9, 2019, between Q32 Bio Inc. and The Regents of the University of Colorado (Filed With SEC on December 18, 2023)

License Agreement, dated as of September 14, 2019, between Q32 Bio Inc. and Bristol-Myers Squibb Company (Filed With SEC on December 18, 2023)

First Amendment to License Agreement, dated as of August 13, 2021, between Q32 Bio Inc. and Bristol-Myers Squibb Company (Filed With SEC on December 18, 2023)

Second Amendment to License Agreement, dated as of July 26, 2022, between Q32 Bio Inc. and Bristol-Myers Squibb Company (Filed With SEC on December 18, 2023)

Third Amendment to License Agreement, dated as of July 26, 2022, between Q32 Bio Inc. and Bristol-Myers Squibb Company (Filed With SEC on December 18, 2023)

Lease Agreement, dated March 20, 2021, by and between Q32 Bio Inc. and PPF OFF 828-830 WINTER STREET LLC (Filed With SEC on December 18, 2023)

Note Purchase Agreement, dated May 20, 2022, by and between Q32 Bio Inc. and the individuals and entities party thereto (Filed With SEC on December 18, 2023)

Amendment No. 1 to Note Purchase Agreement, dated May 20, 2022, by and between Q32 Bio Inc. and the individuals and entities party thereto (Filed With SEC on December 18, 2023)

Loan and Security Agreement, dated as of December 11, 2020, by and between Q32 Bio Inc. and Silicon Valley Bank, as amended (Filed With SEC on December 18, 2023)

First Amendment to Loan and Security Agreement, dated December 30, 2021, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Second Amendment to Loan and Security Agreement, dated June 30, 2022, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Third Amendment to Loan and Security Agreement, dated August 10, 2022, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Fourth Amendment to Loan and Security Agreement, dated December 21, 2022, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Fifth Amendment to Loan and Security Agreement, dated April 26, 2023, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Sixth Amendment to Loan and Security Agreement, dated July12, 2023, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Seventh Amendment to Loan and Security Agreement, dated November 2, 2023, by and between Q32 Bio Inc. and Silicon Valley Bank (Filed With SEC on December 18, 2023)

Q32 Bio Inc. 2017 Stock Option and Grant Plan (Filed With SEC on December 18, 2023)

Agreement and Plan of Merger, dated November 16, 2023, by and among Homology Medicines, Inc., Kenobi Merger Sub, Inc., and Q32 Bio Inc (Filed With SEC on November 16, 2023)

Form of Support Agreement by and between Homology Medicines, Inc. and certain stockholders of Q32 Bio Inc (Filed With SEC on November 16, 2023)

Form of Support Agreement by and between Q32 Bio Inc. and certain stockholders of Homology Medicines, Inc (Filed With SEC on November 16, 2023)

Form of Lock-Up Agreement by and between Q32 Bio Inc. and directors, officers and certain stockholders of Q32 Bio Inc (Filed With SEC on November 16, 2023)

Form of Lock-Up Agreement by and between Q32 Bio Inc. and certain directors of Homology Medicines, Inc (Filed With SEC on November 16, 2023)

Form of CVR Agreement (Filed With SEC on November 16, 2023)

Amendment to Amended and Restated Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and Albert Seymour, Ph.D (Filed With SEC on November 16, 2023)

Second Amendment to Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and W. Bradford Smith (Filed With SEC on November 16, 2023)

Amended and Restated Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and Paul Alloway, Ph.D (Filed With SEC on November 16, 2023)

Employment Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and Charles Michaud, Jr (Filed With SEC on November 16, 2023)

Consulting Agreement, dated November 16, 2023, by and between Homology Medicines, Inc. and W. Bradford Smith (Filed With SEC on November 16, 2023)

Non-Employee Director Compensation Program (Filed With SEC on November 10, 2022)

Amendment to Employment Agreement, dated as of September 6, 2022, between Homology Medicines, Inc. and Paul G. Alloway, Ph.D (Filed With SEC on November 10, 2022)

Amendment to Employment Agreement, dated as of September 6, 2022, between Homology Medicines, Inc. and Michael Blum (Filed With SEC on November 10, 2022)

Consulting Agreement, dated as of September 6, 2022, between Homology Medicines, Inc. and Arthur O. Tzianabos, Ph.D (Filed With SEC on September 8, 2022)

Amendment to Employment Agreement, dated as of September 6, 2022, between Homology Medicines, Inc. and W. Bradford Smith (Filed With SEC on September 8, 2022)

Amended and Restated Employment Agreement, dated as of April 21, 2022, between Homology Medicines, Inc. and Albert Seymour, Ph.D (Filed With SEC on April 21, 2022)

Assignment and Assumption Agreement, dated March 10, 2022, between Homology Medicines, Inc. and Roadrunner Solutions LLC (Filed With SEC on March 23, 2022)

Sublease Agreement, dated March 10, 2022, between Homology Medicines, Inc. and Roadrunner Solutions LLC (Filed With SEC on March 23, 2022)

Employment Agreement, dated March 18 2020, by and between Homology Medicines, Inc. and Paul Alloway, Ph.D (Filed With SEC on March 23, 2022)

Employment Agreement, dated September 1, 2021, by and between Homology Medicines, Inc. and Michael Blum (Filed With SEC on March 23, 2022)

Equity Securities Purchase Agreement, dated January 28, 2022, by and among Homology Medicines, Inc., Roadrunner Solutions LLC, Oxford Biomedica (US), Inc. and, solely for purposes... (Filed With SEC on March 23, 2022)

Amendment No. 1 to Equity Securities Purchase Agreement dated as of January 28, 2022 by and among Homology Medicines, Inc., Roadrunner Solutions LLC, Oxford Biomedica (US), Inc.... (Filed With SEC on March 23, 2022)

Contribution Agreement, dated March 10, 2022, between Homology Medicines, Inc. and Roadrunner Solutions LLC (Filed With SEC on March 23, 2022)

Amended and Restated Limited Liability Company Agreement, dated March 10, 2022, by and among Oxford Biomedica Solutions LLC (f/k/a Roadrunner Solutions LLC), Homology Medicines,... (Filed With SEC on March 23, 2022)

Manufacturing and Supply Agreement, dated March 10, 2022, by and among Homology Medicines, Inc., Roadrunner Solutions LLC and, solely for purposes of Section 2.3(b)(iii) thereof,... (Filed With SEC on March 23, 2022)

Underwriting Agreement, dated April 6, 2021, by and between the Company and BTIG, LLC (Filed With SEC on April 9, 2021)

Description of Securities (Filed With SEC on March 11, 2021)

2018 Incentive Award Plan, and forms of awards thereunder (Filed With SEC on March 11, 2021)

Amended and Restated Investors Rights Agreement, dated July 28, 2017, by and among Homology Medicines, Inc. and the investors named therein, as amended by Amendment No. 1 Amended... (Filed With SEC on November 9, 2020)

Second Amendment to Collaboration and License Agreement, dated October 30, 2020, between Homology Medicines, Inc. and Novartis Institutes for BioMedical Research, Inc (Filed With SEC on November 9, 2020)

Stock Purchase Agreement, dated November 9, 2020, by and between Homology Medicines, Inc. and Pfizer Inc (Filed With SEC on November 9, 2020)

Amendment to Collaboration and License Agreement, dated December 17, 2018, between Homology Medicines, Inc. and Novartis Institutes for BioMedical Research, Inc (Filed With SEC on August 10, 2020)

Description of Securities (Filed With SEC on March 12, 2020)

Non-Employee Director Compensation Program (Filed With SEC on March 12, 2020)

Employment Agreement, November 12, 2019, by and between Homology Medicines, Inc. and Gabriel M. Cohn, M.D (Filed With SEC on March 12, 2020)

Underwriting Agreement, dated April 9, 2019, by and among the Company and Merrill Lynch, Pierce, Fenner & Smith Incorporated and Cowen and Company, LLC, as representatives of the... (Filed With SEC on April 11, 2019)

Employment Agreement, dated April 2, 2018, by and between Homology Medicines, Inc. and Tim Kelly (Filed With SEC on March 12, 2019)

2018 Employee Stock Purchase Plan Offering Document (Filed With SEC on November 13, 2018)

Collaboration and License Agreement, dated November 6, 2017, between the Registrant and Novartis Institutes for BioMedical Research, Inc (Filed With SEC on March 23, 2018)

Form of Underwriting Agreement (Filed With SEC on March 19, 2018)

Specimen Stock Certificate evidencing the shares of common stock (Filed With SEC on March 19, 2018)

2015 Stock Incentive Plan, as amended, and form of option agreements thereunder (Filed With SEC on March 19, 2018)

2018 Incentive Award Plan and form of option agreements thereunder (Filed With SEC on March 19, 2018)

2018 Employee Stock Purchase Plan (Filed With SEC on March 19, 2018)

Non-Employee Director Compensation Program (Filed With SEC on March 19, 2018)

Form of Indemnification Agreement for Directors and Officers (Filed With SEC on March 19, 2018)

Offer Letter to Arthur O. Tzianabos, dated March 31, 2016 (Filed With SEC on March 19, 2018)

Employment Agreement, by and between the Registrant and Siyamak (Sam) Rasty (to be effective upon the closing of this offering) (Filed With SEC on March 19, 2018)

Employment Agreement, by and between the Registrant and Albert Seymour (to be effective upon the closing of this offering) (Filed With SEC on March 19, 2018)

Employment Agreement, by and between the Registrant and Bradford Smith (to be effective upon the closing of this offering) (Filed With SEC on March 19, 2018)

Employment Agreement, by and between the Registrant and Arthur Tzianabos, Ph.D. (to be effective upon the closing of this offering) (Filed With SEC on March 19, 2018)

Collaboration and License Agreement, dated November 6, 2017, between the Registrant and Novartis Institutes for BioMedical Research, Inc (Filed With SEC on March 19, 2018)

Exclusive License Agreement, dated April 28, 2016, between the Registrant and City of Hope (Filed With SEC on March 19, 2018)

License Agreement, dated September 14, 2016, between the Registrant and California Institute of Technology (Filed With SEC on March 19, 2018)

Amended and Restated Investors Rights Agreement dated July 28, 2017, among the Registrant and the investors named therein (Filed With SEC on March 2, 2018)

2015 Stock Incentive Plan, as amended, and form of option agreements thereunder (Filed With SEC on March 2, 2018)

Lease Agreement, dated August 31, 2016, between the Registrant and ARE-MA Region No. 24, LLC (Filed With SEC on March 2, 2018)

Lease Agreement, dated December 21, 2017, between the Registrant and Bedford Patriots Park, LLC (Filed With SEC on March 2, 2018)

Offer Letter to Siyamak (Sam) Rasty, dated December 7, 2015 (Filed With SEC on March 2, 2018)

Offer Letter to Albert Seymour, dated February 14, 2016 (Filed With SEC on March 2, 2018)

Offer Letter to Arthur O. Tzianabos, dated March 31, 2016 (Filed With SEC on March 2, 2018)

Collaboration and License Agreement, dated November 6, 2017, between the Registrant and Novartis Institutes for BioMedical Research, Inc (Filed With SEC on March 2, 2018)

Exclusive License Agreement, dated April 28, 2016, between the Registrant and City of Hope (Filed With SEC on March 2, 2018)

License Agreement, dated September 14, 2016, between the Registrant and California Institute of Technology (Filed With SEC on March 2, 2018)

First Amendment to License Agreement, dated May 16, 2017, between the Registrant and California Institute of Technology (Filed With SEC on March 2, 2018)

Letter Agreement, dated November 14, 2017, between the Registrant and California Institute of Technology (Filed With SEC on March 2, 2018)

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Homology Medicines, Inc. Contracts & Agreements