G1 Therapeutics, Inc. Contracts & Agreements

First Amend (Filed With SEC on November 1, 2023)

G1 Therapeutics, Inc. Deferred Compensation Plan for Non-Employee Directors (Filed With SEC on August 2, 2023)

Form of Performance-Based Restricted Stock Unit Award Agreement under the Amended and Restated 2017 Employee, Director and Consultant Equity Plan (Filed With SEC on May 3, 2023)

Employment Agreement by and between the Registrant and John W. Umstead V, dated as of February 28, 2023 (Filed With SEC on March 1, 2023)

Senior Advisor Agreement between Registrant and Jennifer K. Moses dated February 28, 2023 (Filed With SEC on March 1, 2023)

Underwriting Agreement dated November 17, 2022 by and among G1 Therapeutics, Inc. and Cowen and Company, LLC and Raymond James & Associates, Inc., as representatives of the... (Filed With SEC on November 21, 2022)

Fourth Amendment to Loan and Security Agreement by and between Registrant and Hercules Capital, Inc., dated November 1, 2022 (Filed With SEC on November 2, 2022)

Third Amendment to Loan and Security Agreement, by and between the Registrant and Hercules Capital, Inc., dated June 24, 2022 (Filed With SEC on August 3, 2022)

G1 Therapeutics, Inc. Amended and Restated 2021 Inducement Equity Incentive Plan (Filed With SEC on May 4, 2022)

Sales Agreement by and between the Registrant and Cowen and Company, LLC, dated as of February 23, 2022 (Filed With SEC on February 23, 2022)

Mutual Termination, Release, and Settlement Agreement by and between G1 Therapeutics, Inc. and Boehringer Ingelheim Pharmaceuticals, Inc., dated as of December 15, 2021 (Filed With SEC on February 23, 2022)

Description of Securities of the Registrant (Filed With SEC on February 23, 2022)

G1 Therapeutics, Inc. 2021 Sales Force Inducement Equity Incentive Plan (Filed With SEC on November 3, 2021)

Second Amendment to Loan and Security Agreement, by and between the Registrant and Hercules Capital, Inc., dated November 1, 2021 (Filed With SEC on November 3, 2021)

Employment Agreement by and between Registrant and Andrew Perry dated July 28, 2021 (Filed With SEC on August 4, 2021)

Scientific, Clinical, and Regulatory Advisor Agreement by and between the Registrant and Seth A. Rudnick, MD, effective July 1, 2021 (Filed With SEC on August 4, 2021)

Second Amended and Restated Non-Employee Director Compensation Policy (Filed With SEC on June 21, 2021)

First Amendment to Loan and Security Agreement, by and between the Registrant and Hercules Capital, Inc., dated March 31, 2021 (Filed With SEC on May 5, 2021)

Description of Securities of the Registrant (Filed With SEC on February 24, 2021)

G1 Therapeutics, Inc. 2021 Inducement Equity Incentive Plan (Filed With SEC on February 24, 2021)

Employment Agreement by and between Registrant and John E. Bailey, Jr. dated September 29, 2020 (Filed With SEC on November 4, 2020)

Senior Advisor Agreement between Registrant and John E. Bailey, Jr. dated September 29, 2020 (Filed With SEC on November 4, 2020)

Senior Advisor Agreement between Registrant and Mark A. Velleca, M.D., Ph.D. dated September 29, 2020 (Filed With SEC on November 4, 2020)

Loan and Security Agreement, by and between the Registrant and Hercules Capital, Inc., dated May 29, 2020 (Filed With SEC on August 5, 2020)

Co-Promotion Agreement by and between the Registrant and Boehringer Ingelheim Pharmaceuticals, Inc., dated June 29, 2020 (Filed With SEC on August 5, 2020)

Scientific, Clinical, and Regulatory Advisor Agreement, by and between the Registrant and Seth A. Rudnick, M.D., effective July 1, 2020 (Filed With SEC on August 5, 2020)

Inducement Grant Option Agreement by and between the Registrant and Soma Gupta dated March 31, 2020 (Filed With SEC on May 6, 2020)

Employment Agreement by and between the Registrant and Soma Gupta dated March 12, 2020 (Filed With SEC on May 6, 2020)

Description of Securities of the Registrant (Filed With SEC on February 26, 2020)

Employment Agreement by and between the Registrant and Mark Avagliano, dated as of July 29, 2019 (Filed With SEC on August 7, 2019)

Separation and Transition Agreement by and between Registrant and Barclay Phillips, dated as of May 8, 2019 (Filed With SEC on August 7, 2019)

Amended and Restated Non-Employee Director Compensation Policy (Filed With SEC on June 13, 2019)

Employment Agreement, by and between the Registrant and Rajesh K. Malik, M.D., dated July 1, 2014, as amended; First Amendment effective May 5, 2017, filed as Exhibit 10.5 to the... (Filed With SEC on June 13, 2019)

Employment Agreement, by and between the Registrant and Terry Murdock, dated as of August 1, 2017, as amended; filed as Exhibit 10.1 to the Registrants Quarterly Report on Form... (Filed With SEC on June 13, 2019)

Amended and Restated Employment Agreement by and between the Registrant and Jennifer K. Moses dated May 8, 2019 (Filed With SEC on May 9, 2019)

Underwriting Agreement dated September 18, 2018 by and among G1 Therapeutics, Inc. and J.P. Morgan Securities LLC and Cowen and Company, LLC, as representatives of the several... (Filed With SEC on September 19, 2018)

Employment Agreement by and between the Registrant and John Demaree, dated as of July 3, 2018 (Filed With SEC on August 8, 2018)

Employment Agreement by and between the Registrant and James S Hanson, dated as of June 25, 2018 (Filed With SEC on August 8, 2018)

Amended and Restated 2017 Employee, Director and Consultant Equity Plan (Filed With SEC on August 8, 2018)

Advisory Board Members Agreement, by and between the Registrant and Seth A. Rudnick, M.D., dated July 27, 2018 (Filed With SEC on August 8, 2018)

Form of Underwriting Agreement (Filed With SEC on March 5, 2018)

Third Amendment to Office Lease, by and between the Registrant and Raleigh RC Green, LLC as successor in interest to Highwoods Realty Limited Partnership, dated January 31, 2018 (Filed With SEC on March 5, 2018)

Non-Qualified Stock Option Agreement by and between the Registrant and Barclay A. Phillips, dated December 6, 2017 (Filed With SEC on February 21, 2018)

Employment Agreement between the Company and Barclay A. Phillips, effective as of November 13, 2017 (Filed With SEC on November 13, 2017)

Employment Agreement by and between the Registrant and Terry Murdock, dated as of August 1, 2017 (Filed With SEC on November 8, 2017)

G1 THERAPEUTICS, INC. 2017 EMPLOYEE, DIRECTOR AND CONSULTANT EQUITY INCENTIVE PLAN (Filed With SEC on May 8, 2017)

[ ] G1 THERAPEUTICS, INC. Common Stock UNDERWRITING AGREEMENT (Filed With SEC on May 8, 2017)

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on May 8, 2017)

INDEMNIFICATION AGREEMENT (Filed With SEC on May 8, 2017)

THIRD AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on May 8, 2017)

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on May 8, 2017)

G1 THERAPEUTICS, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY (Filed With SEC on May 8, 2017)

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT (Filed With SEC on May 8, 2017)

CONSULTING AGREEMENT (Filed With SEC on April 13, 2017)

CONFIDENTIAL TREATMENT REQUESTED AMENDMENT NO. 1 TO EXCLUSIVE LICENSE AGREEMENT (Filed With SEC on April 13, 2017)

CONFIDENTIAL TREATMENT REQUESTED EXCLUSIVE LICENSE AGREEMENT (Filed With SEC on April 13, 2017)

SECOND AMENDMENT TO OFFICE LEASE (Filed With SEC on April 13, 2017)

ADVISORY BOARD MEMBER AGREEMENT (Filed With SEC on April 13, 2017)

DIRECTOR AGREEMENT (Filed With SEC on April 13, 2017)

EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on April 13, 2017)

SECOND AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT (Filed With SEC on April 13, 2017)

SIXTH AMENDMENT TO G1THERAPEUTICS, INC. 2011 EQUITY INCENTIVE PLAN (Filed With SEC on April 13, 2017)

SECOND AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT (Filed With SEC on April 13, 2017)

THIRD AMENDED AND RESTATED STOCKHOLDERS AGREEMENT (Filed With SEC on April 13, 2017)

STOCK WARRANT (Filed With SEC on April 13, 2017)

G1 THERAPEUTICS, INC. WARRANT TOPURCHASE STOCK (Filed With SEC on April 13, 2017)