EXACT SCIENCES CORP Contracts & Agreements

Fifth Supplemental Indenture, dated April 17, 2024, between the Company and U.S. Bank National Association, as Trustee (including the form of 1.75% Convertible Senior Notes due... (Filed With SEC on April 17, 2024)

The Registrant's Equity Award, Death, Disability and Retirement Policy (Filed With SEC on February 21, 2024)

The Registrants 2019 Omnibus Long-Term Incentive Plan Form Stock Option Award Agreement (Filed With SEC on August 1, 2023)

The Registrants 2019 Omnibus Long-Term Incentive Plan Form Restricted Stock Unit Award Agreement (Filed With SEC on August 1, 2023)

The Registrants 2019 Omnibus Long-Term Incentive Plan Form Restricted Stock Award Agreement (Filed With SEC on August 1, 2023)

The Registrants 2019 Omnibus Long-Term Incentive Plan Form Deferred Stock Unit Award Agreement (Filed With SEC on August 1, 2023)

Amendment No. 2 to Exact Sciences Corporation 2019 Omnibus Long-Term Incentive Plan (Filed With SEC on June 12, 2023)

The Registrant's 2010 Employee Stock Purchase Plan (as amended and restated March 22, 2023) (Filed With SEC on May 9, 2023)

The Registrant's Non-Employee Director Compensation Policy dated January 24, 2023 (Filed With SEC on May 9, 2023)

Fourth Supplemental Indenture, dated March 1, 2023, between the Company and U.S. Bank National Association, as Trustee (including the form of 2.00% Convertible Senior Notes due... (Filed With SEC on March 1, 2023)

Consulting Agreement, dated December 31, 2022, by and between Scott Coward and the Registrant (Filed With SEC on February 21, 2023)

The Registrant's Equity Award, Death, Disability and Retirement Policy (Filed With SEC on February 21, 2023)

Employment Agreement, dated September 2, 2022, by and between Brian Baranick and the Registrant (Filed With SEC on November 3, 2022)

Receivables Financing Agreement dated as of June 29, 2022 by and among Exact Receivables LLC, as borrower, the persons from time to time party thereto as lenders and group agents,... (Filed With SEC on June 30, 2022)

Receivables Purchase Agreement dated as of June 29, 2022 by and among Exact Sciences Corporation, as seller, Exact Sciences Laboratories, LLC, as initial servicer, and Exact... (Filed With SEC on June 30, 2022)

Receivables Purchase Agreement dated as of June 29, 2022 by and among the entities from time to time party thereto as originators, Exact Sciences Laboratories, LLC, as initial... (Filed With SEC on June 30, 2022)

Amendment No. 1 to Exact Sciences Corporation 2019 Omnibus Long-Term Incentive Plan (Filed With SEC on June 10, 2022)

Amended and Restated Exact Sciences Corporation 2010 Employee Stock Purchase Plan (Filed With SEC on June 10, 2022)

2010 Employee Stock Purchase Plan (As Amended and Restated on March 11, 2022) (Filed With SEC on April 26, 2022)

Non-Employee Director Compensation Policy dated January 25, 2022 (Filed With SEC on April 26, 2022)

Employment Agreement, dated November 11, 2021, by and between Everett Cunningham and the Registrant (Filed With SEC on February 22, 2022)

Description of Common Stock (Filed With SEC on February 16, 2021)

Employment Agreement, dated August 22, 2017, by and between Sarah Condella and the Registrant (Filed With SEC on February 16, 2021)

Employment Agreement, dated August 28, 2017, by and between Ana Hooker and the Registrant (Filed With SEC on February 16, 2021)

The Registrant's Non-Employee Director Compensation Policy dated October 22, 2020 (Filed With SEC on February 16, 2021)

First Amendment to Agreement and Plan of Merger dated December 23, 2020 (Filed With SEC on January 5, 2021)

Second Amendment to Agreement and Plan of Merger dated January 4, 2021 (Filed With SEC on January 5, 2021)

Second Amended and Restated License Agreement, effective January 31, 2020, by and between Mayo Foundation for Medical Education and Research and the Registrant (Filed With SEC on October 27, 2020)

Agreement and Plan of Merger, dated as of October 26, 2020, by and among Exact Sciences Corporation, Eagle Merger Sub I, Inc., Eagle Merger Sub II, LLC, Thrive Earlier Detection... (Filed With SEC on October 27, 2020)

Amended & Restated Cologuard Promotion Agreement by and between Exact Sciences Corporation and Pfizer Inc. dated October 6, 2020 (Filed With SEC on October 7, 2020)

Employment Agreement, dated as of April 20, 2020, by and between Gisela Paulsen and the Registrant (Filed With SEC on July 31, 2020)

The Registrants Non-Employee Director Compensation Policy, dated April 21, 2020 (Filed With SEC on July 31, 2020)

Amendment No. 1 to Construction Loan Agreement and Construction Note, dated June 30, 2020, by and between Fifth Third Bank, National Association and CG Growth LLC (Filed With SEC on July 31, 2020)

Severance and Release of Claims Agreement, dated as of February 3, 2020, by and between G. Bradley Cole and Genomic Health, Inc (Filed With SEC on May 6, 2020)

The Registrants Non-Employee Director Compensation Policy, dated January 28, 2020 (Filed With SEC on May 6, 2020)

Non-Employee Director Compensation Policy dated April 22, 2020 (Filed With SEC on April 24, 2020)

Underwriting Agreement, dated February 24, 2020, by and between the Company and BofA Securities, Inc., as representative of the several underwriters named therein (Filed With SEC on February 27, 2020)

Third Supplemental Indenture, dated February 27, 2020, between the Company and U.S. Bank National Association, as Trustee (including the form of 0.3750% Convertible Senior Notes... (Filed With SEC on February 27, 2020)

First Amendment to Lease Agreement, dated October 4, 2019, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

First Amendment to Lease Agreement, dated September 5, 2006, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Second Amendment to Lease Agreement, dated November 30, 2010, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Third Amendment to Lease Agreement, dated November 11, 2015, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Fourth Amendment to Lease Agreement, dated October 4, 2019, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Employment Agreement, dated September 1, 2017, by and between Torsten Hoof and Genomic Health International Srl (Filed With SEC on February 21, 2020)

First Amendment to Employment Agreement, dated September 11, 2017, by and between Torsten Hoof and Genomic Health International Srl (Filed With SEC on February 21, 2020)

Second Amendment to Employment Agreement, dated November 13, 2020, by and between Torsten Hoof and Genomic Health International Srl (Filed With SEC on February 21, 2020)

Retention Bonus and Retention Equity Letter Agreement, dated as of November 15, 2020, by and between G. Brad Cole and the Registrant (Filed With SEC on February 21, 2020)

Employment Agreement, dated February 18, 2019, by and between Jacob Orville and the Registrant (Filed With SEC on February 21, 2020)

The Registrant's 2019 Omnibus Long-Term Incentive Plan Form Stock Option Award Agreement (Filed With SEC on February 21, 2020)

The Registrant's 2019 Omnibus Long-Term Incentive Plan Form Restricted Stock Unit Award Agreement (Filed With SEC on February 21, 2020)

The Registrant's 2019 Omnibus Long-Term Incentive Plan Form Restricted Stock Award Agreement (Filed With SEC on February 21, 2020)

Lease Agreement, dated November 11, 2015, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Lease Agreement, dated September 23, 2005, by and between Metropolitan Life Insurance Company and Genomic Health, Inc (Filed With SEC on February 21, 2020)

Amendment No. 3 to Exact Sciences Corporation 2010 Employee Stock Purchase Plan (Filed With SEC on July 30, 2019)

Agreement and Plan of Merger, dated as of July 28, 2019, by and among Exact Sciences Corporation, Spring Acquisition Corp. and Genomic Health, Inc (Filed With SEC on July 30, 2019)

Underwriting Agreement, dated March 5, 2019, by and between the Company and Merrill Lynch, Pierce, Fenner & Smith Incorporated, as representative of the several underwriters named... (Filed With SEC on March 8, 2019)

Second Supplemental Indenture, dated March 8, 2019, between the Company and U.S. Bank National Association, as Trustee (including the form of 0.3750% Convertible Senior Notes due... (Filed With SEC on March 8, 2019)

Second Amended and Restated Lease Agreement, dated September 28, 2018, by and between University Research Park Incorporated and the Registrant (Filed With SEC on February 21, 2019)

The Registrants Non-Employee Director Compensation Policy dated January 29, 2019 (Filed With SEC on February 21, 2019)

The Registrants Non-Employee Director Compensation Policy dated October 25, 2018 (Filed With SEC on February 21, 2019)

The Registrants Executive Deferred Compensation Plan dated January 1, 2019 (Filed With SEC on February 21, 2019)

Third Amendment dated effective October 1, 2017 to Amended and Restated License Agreement dated effective January 1, 2019, by and among the Registrant, Mayo Foundation for Medical... (Filed With SEC on February 21, 2019)

Employment Agreement dated September 11, 2017 by and between Scott Johnson and the Registrant (Filed With SEC on February 21, 2019)

Employment Agreement dated April 2, 2018 between the Registrant and Mark Stenhouse (Filed With SEC on October 30, 2018)

First Amendment to Rights Agreement, dated as of October 24, 2018, by and between the Registrant and American Stock Transfer & Trust Company, LLC (Filed With SEC on October 25, 2018)

Promotion Agreement by and between Exact Sciences Corporation and Pfizer Inc. dated August 21, 2018 (Filed With SEC on August 22, 2018)

Underwriting Agreement, dated June 7, 2018, by and between the Company and Merrill Lynch, Pierce, Fenner & Smith Incorporated, as representative of the several underwriters named... (Filed With SEC on June 12, 2018)

Non-Employee Director Compensation Policy, dated January 30, 2018 (Filed With SEC on April 26, 2018)

Employee Transition Agreement, between Maneesh Arora and the Registrant, dated April 25, 2018 (Filed With SEC on April 26, 2018)

Second Amendment dated effective October 1, 2017 to Amended and Restated License Agreement dated effective January 31, 2015, by and among the Registrant, MAYO Foundation for... (Filed With SEC on February 22, 2018)

The Registrants 2010 Omnibus LongTerm Incentive Plan (As Amended and Restated Effective July 27, 2017) Form Incentive Stock Option Award Agreement (Filed With SEC on February 22, 2018)

The Registrants 2010 Omnibus LongTerm Incentive Plan (As Amended and Restated Effective July 27, 2017) Form Restricted Stock Award Agreement (Filed With SEC on February 22, 2018)

The Registrants 2010 Omnibus LongTerm Incentive Plan (As Amended and Restated Effective July 27, 2017) Form Restricted Stock Unit Award Agreement (Filed With SEC on February 22, 2018)

Underwriting Agreement, dated January 11, 2018, by and between the Company and Merrill Lynch, Pierce, Fenner & Smith Incorporated, as representative of the several underwriters... (Filed With SEC on January 17, 2018)

Indenture, dated January 17, 2018, between the Company and U.S. Bank National Association, as Trustee (Filed With SEC on January 17, 2018)

First Supplemental Indenture, dated January 17, 2018, between the Company and U.S. Bank National Association, as Trustee (including the form of 1.0% Convertible Senior Notes due... (Filed With SEC on January 17, 2018)

Loan and Security Agreement, dated as of December 15, 2017, by and between MB Financial Bank, N.A., Exact Sciences Corporation and Exact Sciences Laboratories, LLC (Filed With SEC on December 18, 2017)

Loan Agreement, dated as of December 15, 2017, by and between MB Financial Bank, N.A. and CG Growth LLC (Filed With SEC on December 18, 2017)

Exact Sciences Corporation 2010 Omnibus Long-Term Incentive Plan (As Amended and Restated Effective July 27, 2017) (Filed With SEC on October 30, 2017)

Non-Employee Director Compensation Policy, dated January 31, 2017 and effective July 27, 2017 (Filed With SEC on October 30, 2017)

ROYALTY BUY-OUT AGREEMENT (Filed With SEC on April 27, 2017)

EMPLOYMENT AGREEMENT (Filed With SEC on February 21, 2017)

FIRST AMENDMENT TO MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH AMENDED AND RESTATED LICENSE AGREEMENT (Filed With SEC on May 3, 2016)

EXACT SCIENCES CORPORATION 2016 INDUCEMENT AWARD PLAN (Filed With SEC on May 3, 2016)

EMPLOYMENT AGREEMENT (Filed With SEC on February 24, 2016)

.EMPLOYMENT AGREEMENT (Filed With SEC on February 24, 2016)

Exact Sciences Corporation Non-Employee Director Compensation Policy (Filed With SEC on July 31, 2015)

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH AMENDED AND RESTATED LICENSE AGREEMENT (Filed With SEC on May 4, 2015)

EMPLOYMENT AGREEMENT (Filed With SEC on February 27, 2015)

AMENDMENT ONE TO LEASE (Filed With SEC on February 27, 2015)

LEASE AGREEMENT (Filed With SEC on February 27, 2015)

FIRST AMENDMENT TO LEASE (Filed With SEC on February 27, 2015)

CONFIDENTIAL PORTIONS OF THIS AGREEMENT HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR SUCH PORTIONS. ASTERISKS DENOTE... (Filed With SEC on February 28, 2014)

Exact Sciences Corporation Non-Employee Director Compensation Policy (Filed With SEC on November 1, 2013)

LEASE (Filed With SEC on August 2, 2013)

SEPARATION AGREEMENT AND GENERAL RELEASE (Filed With SEC on June 7, 2013)

CONFIDENTIAL (Filed With SEC on March 1, 2013)

AMENDMENT No. 4 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH LICENSE AGREEMENT (Filed With SEC on July 26, 2012)

EMPLOYMENT AGREEMENT (Filed With SEC on May 4, 2012)

EMPLOYMENT AGREEMENT (Filed With SEC on May 6, 2011)

AMENDED AND RESTATED EMPLOYMENT AGREEMENT (Filed With SEC on March 11, 2011)

EXACT SCIENCES CORPORATION 2010 OMNIBUS LONG-TERM INCENTIVE PLAN Restricted Stock Unit Award Agreement (Filed With SEC on March 11, 2011)

Exact Sciences Corporation Non-Employee Director Compensation Policy (Filed With SEC on March 11, 2011)

RIGHTS AGREEMENT Dated as of February 22, 2011 EXACT SCIENCES CORPORATION and AMERICAN STOCK TRANSFER & TRUST COMPANY, LLC as Rights Agent (Filed With SEC on February 23, 2011)

EXACT SCIENCESCORPORATION 2000 EMPLOYEE STOCK PURCHASEPLAN (Filed With SEC on March 12, 2010)

EXACT Sciences Corporation Non-Employee DirectorCompensation Policy (Filed With SEC on March 12, 2010)

EMPLOYMENT AGREEMENT (Filed With SEC on March 12, 2010)

TECHNOLOGY LICENSE AGREEMENT (Filed With SEC on March 12, 2010)

LOAN AGREEMENT BETWEEN THE WISCONSIN DEPARTMENT OF COMMERCE AND EXACT SCIENCES CORPORATION (Filed With SEC on March 12, 2010)

LEASEAGREEMENT (Filed With SEC on March 12, 2010)

COMMON STOCK PURCHASE WARRANT To Purchase Shares of CommonStock of EXACTSCIENCES CORPORATION (Filed With SEC on August 13, 2009)

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH LICENSE AGREEMENT (Filed With SEC on August 13, 2009)

EXACTCORPORATION 2000STOCK OPTION AND INCENTIVE PLAN (Filed With SEC on March 31, 2009)

FIRST AMENDMENT TO AGREEMENT BETWEEN EXACT SCIENCES CORPORATION AND LABORATORY CORPORATION OF AMERICA HOLDINGS (Filed With SEC on March 31, 2009)

SUBLICENSE AGREEMENT (Filed With SEC on March 31, 2009)

EXACT SCIENCES CORPORATION Incentive Stock Option Agreement Terms and Conditions (Filed With SEC on March 31, 2009)

SEVENTH AMENDMENT TO LICENSE AGREEMENT BETWEEN EXACT SCIENCES CORPORATION AND THE JOHNS HOPKINS UNIVERSITY (Filed With SEC on March 31, 2009)

RELEASE AGREEMENT (Filed With SEC on March 31, 2009)

EMPLOYMENT AGREEMENT (Filed With SEC on March 18, 2009)

COLLABORATION, LICENSE and PURCHASE AGREEMENT BETWEEN GENZYME CORPORATION AND EXACT SCIENCES CORPORATION Dated as of January 27, 2009 (Filed With SEC on January 28, 2009)

ASSIGNMENT, SUBLICENSE, CONSENT AND EIGHTH AMENDMENT TO LICENSE AGREEMENT (Filed With SEC on January 28, 2009)

AMENDED AND RESTATED LICENSE AGREEMENT by and between GENZYME CORPORATION and EXACT SCIENCES CORPORATION (formerly EXACT LABORATORIES, INC.) January 27, 2009 (Filed With SEC on January 28, 2009)

COMMON STOCK SUBSCRIPTIONAGREEMENT (Filed With SEC on January 28, 2009)

SUBLEASE AGREEMENT (Filed With SEC on December 15, 2008)

EXACTSciences Corporation Non-EmployeeDirector Compensation Policy (Filed With SEC on December 15, 2008)

AMENDEDAND RESTATED LICENSEAGREEMENT BETWEEN THE JOHNSHOPKINS UNIVERSITY & EXACTSCIENCES CORPORATION JHU Ref:DM 3562 (Filed With SEC on November 7, 2008)

LICENSE AGREEMENT Case Western Reserve University Exact SciencesCorporation (Filed With SEC on August 8, 2008)

FOURTHAMENDMENT TO AGREEMENT BETWEEN EXACTSCIENCES CORPORATION AND LABORATORYCORPORATION OF AMERICA HOLDINGS (Filed With SEC on May 9, 2008)

Exhibit A General Release of Claims (Filed With SEC on April 22, 2008)

THIRDAMENDMENT TO AGREEMENT BETWEEN EXACT SCIENCES CORPORATION AND LABORATORY CORPORATION OF AMERICA HOLDINGS (Filed With SEC on September 7, 2007)

(1) Date of Option (Filed With SEC on September 7, 2007)

EXACTSciences Corporation Non-Employee Director Compensation Policy (Filed With SEC on August 15, 2007)

Performance Level Corporate Calculation for Value of Payout 100% (i.e., 5/5 objectives achieved) 2.5 times Individual Cash Payout 80% (i.e., 4/5 objectives achieved) 2.0 times... (Filed With SEC on August 15, 2007)

SECONDAMENDMENT TO AGREEMENT BETWEEN EXACT SCIENCES CORPORATION AND LABORATORY CORPORATION OF AMERICA HOLDINGS (Filed With SEC on July 3, 2007)

LICENSE AGREEMENT (Filed With SEC on March 15, 2007)

EMPLOYMENTAGREEMENT (Filed With SEC on June 29, 2006)

EXECUTIVE AGREEMENT (Filed With SEC on April 14, 2006)

AMENDMENT NO. 1 TO COMMON STOCKPURCHASE WARRANT (Filed With SEC on June 27, 2005)

EXACT SCIENCES CORPORATION 2000EMPLOYEE STOCK PURCHASE PLAN (Filed With SEC on May 6, 2005)

EXECUTIVE AGREEMENT (Filed With SEC on November 12, 2004)

EXACTSCIENCES CORPORATION Nonstatutory (Non-Qualified) Stock Option Agreement Cover Sheet (Filed With SEC on November 4, 2004)

EXACT SCIENCES CORPORATION Incentive Stock Option Agreement Terms and Conditions (Filed With SEC on October 1, 2004)

SERVICES, MANUFACTURING AND SUPPLYAGREEMENT (Filed With SEC on July 30, 2003)

Warrant No. 4 Number of Shares 1,000,000 (Filed With SEC on August 14, 2002)

AGREEMENT (Filed With SEC on August 14, 2002)

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EXACT SCIENCES CORP Contracts & Agreements