Amendment and Extension of Advisory Engagement Agreement between Epoch Biosciences, Inc. and Bay City Capital BD LLC

Summary

Epoch Biosciences, Inc. and Bay City Capital BD LLC have agreed to extend the term of their existing advisory engagement, originally set to end on November 7, 2001, until May 7, 2002. All other terms of the original agreement remain unchanged. This letter serves as a binding amendment to the original agreement, confirming the extension of the advisor's services for the specified period.

EX-10.26.1 6 a79178ex10-26_1.txt EXHIBIT 10.26.1 EXHIBIT 10.26.1 November 13, 2001 Bay City Capital LLC 750 Battery Street, Suite 600 San Francisco, CA 94111 Attn: Sanford S. Zweifach Re: Extension of Letter Agreement between Epoch Biosciences, Inc. and Bay City Capital BD LLC Dear Mr. Zweifach: Reference is made to the Letter Agreement between Epoch Biosciences, Inc. (the "Company") and Bay City Capital BD, LLC., (the "Advisor") dated November 7, 2000 with respect to the engagement of Advisor by the Company (the "Agreement"). Pursuant to Paragraph 13 of the Agreement, the term of Advisor's engagement ends effective November 7, 2001. This Letter is to document our mutual agreement that the term of Advisor's engagement shall continue until May 7, 2002, pursuant to the terms of the Agreement. All other provisions of the Agreement shall remain in full force and effect. If the foregoing correctly sets forth the understanding agreement between Advisor and Company, please so indicate in the space provided below, whereupon this letter shall constitute a binding amendment and extension of the Agreement. Very truly yours, EPOCH BIOSCIENCES, INC. /s/ William G. Gerber ------------------------------------ William G. Gerber, M.D., Chief Executive Officer Agreed to and accepted this 15th day of November, 2001 /s/ Sanford S. Zweifach - -------------------------------------- Bay City Capital BD LLC By: Sanford S. Zweifach Its: President