REVISEDBUDGET YEAR16 PERIOD:March 1, 2014 – August 31, 2014

March 1, 2014

Judy Brown
Senior Manager - Contracts Research & Industrial Grants
Office of Research, Needles Hall Room 1043
University of Waterloo
200 University Ave W
Waterloo, ON N2L 3G1

Dear Ms. Brown:

Pursuant to the Research Agreement effective September 1, 1998, as amended on June 11, 2012 and September 1, 2013 (the “Agreement”), copy attached, between the University of Waterloo (“Waterloo”), Dr. John E. Thompson (“Thompson”), and Senesco, Inc. (“Senesco”), Waterloo, Thompson and Senesco hereby agree to amend the Budget set forth in the Revised Budget for Year 16, effective March 1, 2014, through August 31, 2014 and (ii) that Article IV, Section A of the Agreement is hereby amended and restated in its entirety to read: “Senesco agrees to pay for the cost of work specified in the Budget as set forth in Exhibit A, which Budget may be revised from time to time upon mutual agreement of the Parties. Payment shall be made according to the Payment Schedule provided in Exhibit B. Payment is to be made by Senesco in Canadian dollars.” The Amended Revised Budget for Year 16 supercedes and replaces the previous Budget for Year 16 of the Agreement for all work commencing on or after March 1, 2014.

Agreed and Accepted:

University of Waterloo

/s/ Dr. John Thompson, Ph.D.

Dr. John Thompson, Ph.D.

REVISED BUDGET

YEAR 16

PERIOD: March 1, 2014 – August 31, 2014