Amendment No. 2 to Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. and DURECT Corporation

Summary

This amendment, dated November 22, 2004, updates the Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. and DURECT Corporation. The amendment changes certain key dates in the original agreement, moving deadlines from January 1 and January 31, 2005, to January 1 and January 31, 2006. All other terms of the original agreement remain unchanged. Both parties have agreed to these modifications as indicated by their signatures.

EX-10.41 2 dex1041.htm AMENDMENT 2 TO DEVELOPMENT, COMMERCIALIZATION AND SUPPLY LICENSE AGREEMENT Amendment 2 to Development, Commercialization and Supply License Agreement

Exhibit 10.41

 

                                November 22, 2004

 

BY FACSIMILE AND EXPRESS MAIL

CONFIDENTIAL

Peter A. Lankau

President

Endo Pharmaceuticals Inc.

100 Painters Drive

Chadds Ford, PA 19317

 

Re: Amendment 2 to Development, Commercialization and Supply License Agreement

 

Dear Peter:

 

Reference is made to the Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. (“Endo”) and DURECT Corporation (“DURECT”) effective November 8, 2002, as amended effective January 28, 2004 (“Agreement”). Effective on the date written above, Endo and DURECT hereby agree to amend the Agreement as follows:

 

  1. Amendment to Section 4.6(a). Section 4.6(a) of the Agreement shall be amended to replace each instance of “January 1, 2005” with “January 1, 2006”.

 

  2. Amendment to Section 4.6(c). Section 4.6(c) of the Agreement shall be amended to replace each instance of “January 1, 2005” with “January 1, 2006”.

 

  3. Amendment to Section 13.3(e). Section 13.3(e) of the Agreement shall be amended to replace “January 1, 2005” with “January 1, 2006” and “January 31, 2005” with “January 31, 2006”.

 

Except as set forth above, all other terms of the Agreement shall remain the same. Please sign below to indicate Endo’s agreement to the foregoing.

 

Very truly yours,

/s/ James E. Brown


James E. Brown

President and CEO

 

AGREED TO BY ENDO:

By:

 

/s/ Peter A. Lankau


   

Peter A. Lankau

   

President

 

Date: Nov. 22, 2004