Amendment No. 2 to Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. and DURECT Corporation
This amendment, dated November 22, 2004, updates the Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. and DURECT Corporation. The amendment changes certain key dates in the original agreement, moving deadlines from January 1 and January 31, 2005, to January 1 and January 31, 2006. All other terms of the original agreement remain unchanged. Both parties have agreed to these modifications as indicated by their signatures.
Exhibit 10.41
November 22, 2004
BY FACSIMILE AND EXPRESS MAIL
CONFIDENTIAL
Peter A. Lankau
President
Endo Pharmaceuticals Inc.
100 Painters Drive
Chadds Ford, PA 19317
Re: Amendment 2 to Development, Commercialization and Supply License Agreement
Dear Peter:
Reference is made to the Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. (Endo) and DURECT Corporation (DURECT) effective November 8, 2002, as amended effective January 28, 2004 (Agreement). Effective on the date written above, Endo and DURECT hereby agree to amend the Agreement as follows:
1. | Amendment to Section 4.6(a). Section 4.6(a) of the Agreement shall be amended to replace each instance of January 1, 2005 with January 1, 2006. |
2. | Amendment to Section 4.6(c). Section 4.6(c) of the Agreement shall be amended to replace each instance of January 1, 2005 with January 1, 2006. |
3. | Amendment to Section 13.3(e). Section 13.3(e) of the Agreement shall be amended to replace January 1, 2005 with January 1, 2006 and January 31, 2005 with January 31, 2006. |
Except as set forth above, all other terms of the Agreement shall remain the same. Please sign below to indicate Endos agreement to the foregoing.
Very truly yours, |
/s/ James E. Brown |
James E. Brown |
President and CEO |
AGREED TO BY ENDO: | ||
By: | /s/ Peter A. Lankau | |
Peter A. Lankau | ||
President |
Date: Nov. 22, 2004