EMPLOYMENT AGREEMENT

Exhibit 10.8

EMPLOYMENT AGREEMENT

THIS AGREEMENT made as of the 13^th day of May, 2015.

BETWEEN:

CYNAPSUS THERAPEUTICS INC.

(hereinafter called “Cynapsus”)

- and -

thierry bilbault

(hereinafter called the “Executive”)

WHEREAS Cynapsus is developing a sublingual thin filmstrip for the acute rescue of OFF motor symptoms of Parkinson’s disease;

AND WHEREAS Cynapsus and the Executive entered into an original employment agreement dated as of October 6^th, 2014, as amended on January 1, 2015;

AND WHEREAS Cynapsus and the Executive have agreed to further amend the terms of the employment relationship.

NOW THEREFORE THIS AGREEMENT WITNESSES that in consideration of the mutual covenants and agreements contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties covenant and agree as follows:

Article 1 - DUTIES

1.1                        The Executive will be the Chief Scientific Officer and Executive Vice President, Chemistry, Manufacturing and Controls, and will exercise all of the duties and responsibilities of such office and will perform such other services as the board of directors of Cynapsus (the “Board”) may reasonably request of the Executive from time to time. The duties of the Executive shall include, but are not limited to, assisting with strategic planning, vendor selection, product formulation and development, API sourcing, specifications and analytics, bioanalytics, packaging, intellectual property, supporting clinical research activities and regulatory affairs, partnering, and communicating with institutional investors and biotechnology analysts. The Executive will report to the President and CEO. In addition, the Executive shall serve in such other capacities, perform such other duties and exercise such other powers consistent with the Executive’s position, training and experience as may from time to time be assigned to or vested in him by the Board. In carrying out his duties hereunder, the Executive agrees to comply with all applicable laws.

1.2                        During his employment hereunder, the Executive shall devote his full time and attention to the business and affairs of Cynapsus and shall well, honestly and faithfully serve Cynapsus and use his best efforts to promote the best interests and goodwill of Cynapsus. This does not preclude the Executive from investing in private investment opportunities it being understood that such opportunities will take immaterial time commitments, and provided that such opportunities are not competitive with Cynapsus or its suppliers.

1.3                        During his employment hereunder, the Executive agrees to spend no less than four working days per work week working in the office of Cynapsus in Toronto, Ontario, unless otherwise mutually agreed between the Executive and Cynapsus, and subject to travel required in connection with his duties hereunder.

1.4                        The Executive hereby confirms his employment with Cynapsus on the terms and conditions set forth in this Agreement.

Article 2 - TERM

2.1                        The parties acknowledge that the Executive has already commenced employment with Cynapsus and that such employment shall continue for an indefinite term until terminated in accordance with the provisions of this Agreement.

Article 3 - COMPENSATION

3.1                        For the performance of his services hereunder and commencing on January 1, 2015, the Executive shall be paid:

(a)          A base salary (the “Base Salary”) of $267,500 per annum, less statutory withholdings, which Cynapsus shall pay to the Executive in equal instalments on those dates on which Cynapsus normally makes salary payments to its employees and in accordance with Cynapsus’ regular practices in this regard.

(b)          A discretionary bonus (the “Annual Bonus”), as determined by the President and CEO and the Board, for each year of the Executive’s employment hereunder, in an amount equal to 30% of the Base Salary, based on the achievement of agreed-upon corporate objectives. The Annual Bonus may be increased to up to 40% of the Base Salary, as determined by the Board, based on an overachievement of goals. The Annual Bonus shall be based on criteria to be approved by the Board, and relayed to the Executive, which criteria shall reflect the annual corporate goals of Cynapsus and individual goals relating to the Executive’s areas of oversight.

3.2                        The Executive shall be entitled to annual reviews of his Base Salary and Annual Bonus or any changes to the bonus plan or other forms of compensation paid or granted to the Executive by Cynapsus as may be determined from time to time by the Board. The Base Salary will take into account the prevailing market conditions and comparative base salaries as well as changes in Cynapsus’ financial conditions, market capitalization, growth and corporate size, however measured.

3.3                         The Executive may be granted options to acquire common shares in the capital of Cynapsus at the discretion of the Board and pursuant to the terms and conditions of Cynapsus’ stock option plan (the “Plan”). Upon a Change of Control (as defined below) of Cynapsus all stock options will vest immediately upon approval by the Board.

Article 4 - EXPENSES

4.1                        It is understood and agreed that the Executive will incur expenses in connection with performing his duties hereunder. Cynapsus will reimburse the Executive for all expenses reasonably and properly incurred by the Executive on behalf of Cynapsus, provided that the Executive provides to Cynapsus receipts acceptable to Cynapsus within a reasonable period after they have been incurred. All expenses shall be incurred in accordance with agreed-upon corporate policies and budgets.

Article 5 - BENEFITS

5.1                        The Executive shall be entitled to five weeks’ paid vacation per year to be taken at such times and for such durations as are acceptable to Cynapsus and the Executive. Up to two weeks’ vacation which, if not taken in any year, may be taken in any subsequent year or the Executive shall be entitled to such vacation pay as may be required pursuant to the Employment Standards Act, 2000 (Ontario). The Executive shall also be entitled to vacation time: (i) during the week between Christmas day and New Year’s day during which Cynapsus’s office is closed; and (ii) on all statutory holidays in the Province of Ontario.

5.2                        The Executive shall be eligible to participate in the group insurance and benefit plan provided to all senior executives of Cynapsus, to the extent he qualifies for such benefits. The Executive’s insurance and benefit entitlements shall be subject to and governed by the terms and conditions of the plan, as amended from time to time.

Article 6 - TERMINATION

(a)          Cynapsus shall be entitled, in its sole discretion, to terminate the employment of the Executive hereunder, without notice or payment in lieu of notice, for Cause (as hereinafter defined). Cynapsus shall have no obligation to the Executive after the effective date of termination pursuant to this Section 6.1 except for payment of any Base Salary accrued to the date of termination and any other amounts which have accrued but not yet been paid in accordance with any benefit plan prior to the date of termination. The Executive shall not be entitled to receive any bonus whatsoever in the event of termination pursuant to this Section 6.1.

(a)          Except as otherwise provided, Cynapsus shall be entitled in its sole discretion to terminate this Agreement at any time without Cause upon six months’ plus one additional month’s notice to the Executive for every full year of employment (starting from October 4, 2014), to a maximum of 12 months, or payment in lieu of notice.

(b)          Upon termination by Cynapsus in accordance with this Section 6.2, Cynapsus shall provide the Executive with written notice or payment in lieu thereof and an amount equal to the average of the Annual Bonus paid to the Executive in each of the three most recent completed financial years of Cynapsus (or such fewer number of recent completed financial years if the Executive was employed for less than the three most recent completed financial years), pro-rated to the effective date of termination (the “Deemed Annual Bonus”), together with all amounts which the Executive would have been entitled to during such period and a continuation of benefits coverage during such period in respect of the elements which are permitted to be continued in accordance with the terms of any benefit plan then in place and applicable laws. Cynapsus shall have the option to pay the amount equal to the Base Salary on its regular payroll dates or in a lump sum as of the effective date of termination.

(a)          The Executive shall be entitled in his sole discretion to terminate this Agreement for any reason whatsoever at any time upon 60 days’ prior written notice to Cynapsus.

(b)          Upon termination by the Executive in accordance with this Section 6.3, Cynapsus shall have no obligation to the Executive after the effective date of termination except for payment of any Base Salary accrued to the date of termination, the Deemed Annual Bonus and any other amounts which have accrued but not yet been paid prior to the date of termination, including any amounts owing in accordance with any benefit plan.

(b)          In the event of termination by the Executive in accordance with Section 6.4(a)(i) or 6.4(a)(ii), Cynapsus shall pay to the Executive a lump sum equal to six months plus one additional month for every full year of employment (starting from October 4, 2014) of Base Salary, to a maximum of 12 months, and the Deemed Annual Bonus, together with all amounts which the Executive would have been entitled to during such period and a continuation of benefits coverage during such period in respect of the elements which are permitted to be continued in accordance with the terms of any benefit plan then in place and applicable laws.

(c)          In the event of termination by Cynapsus in accordance with Section 6.4(a)(i) or 6.4(a)(ii), Cynapsus shall have no obligation to the Executive after the effective date of termination except for payment of any Base Salary accrued to the date of termination and any other amounts which have accrued but not yet been paid prior to the date of termination, including any amounts owing in accordance with any benefit plan. The Executive shall not be entitled to receive any bonus whatsoever in the event of termination by Cynapsus pursuant to Section 6.4(a)(i) or 6.4(a)(ii).

(a)          Upon a Change of Control (as defined below) and for a period of nine months thereafter, in the event of termination of this Agreement by Cynapsus, or the purchaser or other third party, as the case may be, other than for Cause, or by the Executive for Good Reason (as defined below), Cynapsus, or the purchaser or other third party, as the case may be, shall pay to the Executive a lump sum equal to 12 months of Base Salary and the Deemed Annual Bonus, together with all amounts which the Executive would have been entitled to during such period and a continuation of benefits coverage during such period in respect of the elements which are permitted to be continued in accordance with the terms of the benefit plan then in place and applicable laws.

(c)          For the purposes hereof, “Good Reason” shall mean an adverse material change to the terms and conditions of the Executive’s employment including, but not limited to:

(a)          In the event of the Executive’s death then this Agreement shall immediately terminate. In the event of the Disability (as hereinafter defined) of the Executive, Cynapsus shall have the right to terminate this Agreement upon written notice given to the Executive while the Disability is continuing, which termination shall be effective on the date that the notice is given.

(b)          In the event of the death or Disability of the Executive, Cynapsus shall pay to the Executive an amount equal to the Base Salary accrued to the date of termination and the Deemed Annual Bonus, together with all amounts which have accrued but not yet been paid prior to the date of termination, including any amounts owing in accordance with any benefit plan.

in the opinion of a qualified medical practitioner who shall be satisfactory to Cynapsus, acting reasonably; or

6.7                        Upon termination of this Agreement by either party for any reason, other than termination by Cynapsus pursuant to Section 6.1 or Section 6.4(a)(i), the Executive shall have the right to exercise any options granted by Cynapsus in accordance with the Plan.

6.8                        Upon termination of this Agreement by Cynapsus pursuant to Section 6.1 or Section 6.4(a)(i), any options granted by Cynapsus or any unexercised portion thereof shall immediately terminate.

(a)          The parties confirm that the provisions contained in this Article 6, including the notice and pay in lieu of notice provisions contained therein, are valid and reasonable and are fair and equitable. The parties agree that upon any termination of the Executive’s employment by Cynapsus in accordance with the provisions of this Agreement, the Executive shall have no action, cause of action, claim or demand against Cynapsus or any other person as a consequence of such termination. The Executive further acknowledges and agrees that the payments and/or notices required pursuant to this Agreement shall be in full satisfaction of all claims for termination of his employment, including termination pay and/or severance pay pursuant to the Employment Standards Act, 2000 (Ontario) (as the same may be amended or replaced, from time to time). Except as otherwise provided in this Article 6, the Executive shall not be entitled to any further termination or severance payments, damages or other compensation whatsoever.

(b)          As a condition precedent to any payment pursuant to this Article 6, the Executive agrees to deliver to Cynapsus contemporaneously with any such payment, a full and final release of and from all actions or claims in connection therewith in favour of Cynapsus and their respective directors, officers, employees and agents, in form and substance satisfactory to Cynapsus, acting reasonably. If the Executive is an officer or director of Cynapsus at the relevant time of termination of his employment in accordance with the terms hereof, the Executive agrees that contemporaneously with or as soon as is practicable after the termination of his employment hereunder for any reason whatsoever, he will tender his resignation from any position he may hold as an officer and/or director of Cynapsus.

Article 7 - NON-DISCLOSURE, NON-SOLICITATION AND NON-COMPETITION AGREEMENT

7.1                        The Executive has entered into a Non-Disclosure, Non-Solicitation and Non-Competition Agreement in substantially the same form entered into between Cynapsus and its other senior officers.

7.2                        The Executive acknowledges and agrees that the employment relationship will be governed by this Agreement and the standards and terms established by Cynapsus’ policies as they are amended from time to time. The Executive agrees to comply with the terms of Cynapsus’ current and future policies so long as they are not inconsistent with the provisions of this Agreement. In the event Cynapsus’ policies or procedures are in conflict with this Agreement the terms of this Agreement shall prevail.

Article 8 - NEW AND ADDITIONAL CONSIDERATION

8.1                        The Executive acknowledges and agrees that the increase in the amount payable to the Executive pursuant to this Agreement upon a Change of Control constitutes new and additional consideration in favour of the Executive in connection with the execution and delivery of this Agreement by the Executive.

Article 9 - NOTICES

9.1                        Any notice required or permitted to be given to the Executive shall be sufficiently given if delivered to the Executive personally or if mailed by registered mail to the Executive’s address last known to Cynapsus or by e-mail at ***@***.

9.2                        Any notice required or permitted to be given to Cynapsus shall be sufficiently given if mailed by registered mail to Cynapsus’ head office at its address last known to the Executive.

Article 10 - GENERAL

In the event that any provision or part of this Agreement shall be deemed void or invalid by a court of competent jurisdiction, the remaining provisions or parts shall be and remain in full force and effect.

This Agreement shall enure to the benefit of, and be binding on, the parties and their respective heirs, administrators, executors, successors and permitted assigns. Cynapsus shall have the right to assign this Agreement to any successor (whether direct or indirect, by purchase, amalgamation, arrangement, merger, consolidation or otherwise) to all or substantially all of the business and/or assets of Cynapsus provided that such entity assumes all obligations of Cynapsus hereunder. The Executive shall not assign or transfer, whether absolutely, by way of security or otherwise, all or any part of the Executive’s rights or obligations under this Agreement.

This Agreement, together with the Non-Disclosure, Non-Solicitation and Non-Competition Agreement dated as of October 6, 2014, constitutes the entire agreement between the parties with respect to the employment and appointment of the Executive and any and all other previous agreements, written or oral, express or implied, between the parties or on their behalf, relating to the employment and appointment of the Executive by Cynapsus, including but not limited to any previous Consulting Agreements between the Executive and Cynapsus, are hereby terminated and cancelled and each of the parties releases and forever discharges the other of and from all manner of actions, causes of action, claims and demands whatsoever, under or in respect of any such agreements so terminated and cancelled.

Any modification to this Agreement must be in writing and signed by the parties or it shall have no effect and shall be void. No waiver of any breach or default hereunder shall be considered valid unless in writing, and no such waiver shall be deemed a waiver of any subsequent breach or default of the same or similar nature.

The headings used in this Agreement are for convenience only and are not to be construed in any way as additions to or limitations of the covenants and agreements contained in it.

This Agreement shall be construed in accordance with the laws of the Province of Ontario.

Time shall be of the essence of this Agreement.

All amounts payable pursuant to this Agreement are expressed in and shall be paid in Canadian currency.

The Executive acknowledges that he has had an opportunity to seek independent legal advice prior to their execution of this Agreement. The Executive acknowledges that he has sought and obtained such independent advice, or has declined seeking such advice, despite having been given the opportunity to do so.

This Agreement may be signed in one or more counterparts, each of which so signed shall be deemed to be an original, and such counterparts together shall constitute one and the same instrument. Notwithstanding the date of execution or transmission of any counterpart, each counterpart shall be deemed to have the effective date first written above.

[Signature Page Follows]

IN WITNESS WHEREOF this Agreement has been executed by the parties as of the date first written above.