CYGNUS, INC. By: /s/ John C Hodgman Name: John C Hodgman Title: Chairman, President and CEO cc: Arnold & Porter 1600 Tysons Blvd. McLean, Virginia 22102 Attn. L. Stevenson Parker Facsimile No.: (703) 720 7399

Exhibit 10.128

March 24, 2004

Cripple Creek Securities, LLC
195 Maplewood Avenue
Maplewood, New Jersey 07040
Attention: Maurice Hryshko, Counsel and Attorney in Fact
Facsimile No.: (973)  ###-###-####

Re: Notice of Termination of Structured Equity Line Flexible Financing Agreement

Pursuant to Section 10.4 of the Structured Equity Line Flexible Financing Agreement dated as of October 1, 2001 (the “Agreement”), between Cripple Creek Securities, LLC, and Cygnus, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), the Company hereby terminates the Agreement.