Amendment 1 to Monitoring Services Agreement between Cubist Pharmaceuticals, Inc. and Clindev (Proprietary) Limited

Summary

This amendment updates the original monitoring services agreement between Cubist Pharmaceuticals, Inc. (the Sponsor) and Clindev (Proprietary) Limited. It revises payment terms, specifying that Clindev will be paid a set amount per completed patient for services related to a clinical study, covering all activities from protocol review to study closeout. The amendment is effective as of June 21–22, 2000, and is signed by authorized representatives of both parties. Some financial details are confidential and have been omitted from the public version.

EX-10.56 9 a2042768zex-10_56.txt EXHIBIT 10.56 EXHIBIT 10.56 CONFIDENTIAL TREATMENT CONTRACT OF MONITORING SERVICES AMENDMENT 1 Between CUBIST PHARMACEUTICALS, INC Duly represented by Michael F. de Bruin (Hereinafter referred to as "SPONSOR") And CLINDEV (PROPRIETARY) LIMITED Duly represented by MRS. A. LESSING (Hereinafter referred to as "Clindev") *Confidential treatment requested: Material has been omitted and filed with the Commission. -2- Upon mutual agreement of the parties the following sections of the contract are amended as follows: *Confidential treatment requested: Material has been omitted and filed with the Commission. -3- SECTION 4. PAGE 3 PAYMENT FOR SERVICES 4.1 SPONSOR shall pay to Clindev $[ ]* (the "Contract Price") for the services rendered under the Agreement in accordance with the payment schedule set forth in section 4.2. For the purposes of the Agreement, the contract value is based on the inclusion of [ ]* patients ($[ ]* per completed patient) and includes all activities from the first review of the Protocol till the Study is finally closed out and all correction log forms have been processed subject to section 3. In witness whereof, the parties have caused this Amendment to the Agreement to be executed by the respective duly authorized officers as of the dates set forth below. Thus done and signed at: CPI on this the 21st Day of June, 2000. For: the SPONSOR By: /s/ MICHAEL F. DEBRUIN ---------------------- Name: Michael F. DeBruin Title: Vice President, Clinical Research WITNESS: 1. By: /s/ EDWARD S. CAMPANARO ----------------------- Name: Edward S. Campanaro Title: Director, Clinical Operations *Confidential treatment requested: Material has been omitted and filed with the Commission. -4- 2. By: /s/ TANIA ASSAYLEEN ------------------- Name: Tania Assayleen Title: Clinical Trial Manager Thus done and signed at Lynnwood, Pretoria, on this the 22nd Day of June 2000. For: Clindev (Pty) Ltd By: /s/ ANITA LESSING ----------------- Name: Anita Lessing Title: Director WITNESS: 1. By: /s/ SONIA SUTHERLAND -------------------- Name: Sonia Sutherland Title: Research Associate 2. By: /s/ C.S. NASH ------------- Name: C.S. Nash Title: Clinical Research Associate *Confidential treatment requested: Material has been omitted and filed with the Commission.