Amendment No. 2, dated as of April 2

1.Each of the parties hereto agrees that, effective as of the Amendment No. 2 Effective Date (as defined below):

(a)    Section 7.02 of the Existing Credit Agreement is hereby amended to (i) delete the “and” at the end of clause (q), (ii) replace the “.” at the end of clause (r) with “; and” and (iii) insert the following as a new clause (s):

(s)     Guarantees by Borrower of obligations of Restricted Subsidiaries that are not Loan Parties incurred in the ordinary course of such Restricted Subsidiaries’ respective businesses, other than obligations for borrowed money or in respect of Capitalized Leases.

(b) Section 7.03 of the Existing Credit Agreement is hereby amended to (i) delete the “and” at the end of clause (p), (ii) replace the “.” at the end of clause (q) with “; and” and (iii) insert the following as a new clause (r):

(r)    Investments in the ordinary course consisting of deposits of a Loan Party in one or more accounts of a Restricted Subsidiary that is not a Loan Party in connection with Cash Management Services which accounts are not subject to a lien in favor of any Person and for which such Loan Party is the record beneficial owner of the notional balance of such deposit.

(c)     Section 7.09 of the Existing Credit Agreement is hereby amended and restated in its entirety as follows:

Enter into any Contractual Obligation (other than this Agreement or any other Loan Document) that (a) limits the ability (i) of any Restricted Subsidiary to make Restricted Payments to the Borrower or any Guarantor or to otherwise transfer property to the Borrower or any Guarantor, (ii) of any Restricted Subsidiary to Guarantee the Indebtedness of the Borrower or (iii) of the Borrower or any Restricted Subsidiary to create, incur, assume or suffer to exist Liens on property of such Person; provided, however, that clause (i) and clause (iii) shall not prohibit (x) any restriction on transfer or negative pledge incurred or provided in favor of any holder of Indebtedness permitted under Section 7.02(e) (solely to the extent any such restriction on transfer or negative pledge relates to the property financed by or the subject of such Indebtedness) or (y) any requirement to maintain a specified net worth or to satisfy specified financial covenants; or (b) requires the grant of a Lien (other than Liens permitted under Section 7.01) to secure an obligation of such Person if a Lien is granted to secure another obligation of such Person; provided, however, that this Section 7.09 shall not prohibit any such limitations or requirements that are binding on a Person at the time such Person first became a Restricted Subsidiary of the Borrower or is merged into or consolidated with the Borrower or any Restricted Subsidiary, so long as all such limitations and requirements were not entered into in contemplation of such Person becoming a Restricted Subsidiary of the Borrower or merging into or consolidating with the Borrower or any Restricted Subsidiary, together with any replacement agreement thereof so long as the terms thereof are not materially less favorable to the Borrower or such Restricted Subsidiary. Notwithstanding the forgoing, the Borrower and its Restricted Subsidiaries may enter into a Contractual Obligation (t) including any encumbrance or restriction effected in connection with a Qualified Receivables Financing that, in the good faith determination of the Borrower, are necessary or advisable to effect such Qualified Receivables Financing, (u) that has restrictions described in clause (a) above by reason of customary provisions restricting assignments, subletting or other transfers contained in leases, licenses, joint venture agreements and similar agreements entered into in the ordinary course of business, in each case, relating solely to the assets subject to such lease or license or assets relating solely to the assets of such joint venture, (v) that has restrictions described in clause (a)(i) above to the extent such restriction only restricts assignments of such contracts entered into in the ordinary course of business, (w) that has restrictions described in clause (a) above by virtue of customary provisions in asset sale and stock sale agreements and other similar agreements entered into in the ordinary course of business permitted under the terms of this Agreement to the extent such restriction only restricts the transfer of ownership interests in the assets or stock that is to be sold pursuant thereto, pending the sale of such assets, (x) that has restrictions described in clause (a) above by virtue of restrictions on cash or deposits or net worth imposed by customers, suppliers or landlords or required by insurance, surety or bonding

companies under contracts entered into, in each case, in the ordinary course of business, (y) that has restrictions described in clause (a)(iii) above by virtue of restrictions on cash or deposits or net worth imposed in connection with Cash Management Agreements or otherwise imposed by financial institutions, in either case, in the ordinary course of business, and (z) that has restrictions described in clause (a) above imposed by any Governmental Authority or arising by reason of applicable Law, rule, regulation or order or the terms of any license, authorization, concession or permit.

(d)    Section 7.11(a) of the Existing Credit Agreement is hereby amended and restated in its entirety as follows:

2.Borrower’s Certifications. By its execution of this Amendment, the undersigned officer of the Borrower, to the best of his or her knowledge, hereby certifies, solely in his or her capacity as an officer of the Borrower, and not in his or her individual capacity, that:

3.     Amendment No. 2 Effective Date Conditions. This Amendment will become effective on the                 

date (the “Amendment No. 2 Effective Date”) on which each of the following conditions is     

satisfied:

(c)Prior to or substantially concurrently with the Amendment No. 2 Effective Date, the Borrower shall have paid to the Administrative Agent, for the benefit of each Lender that has delivered a counterpart of this Amendment to the Administrative Agent, a consent fee equal to 0.075% multiplied by the sum of (i) the aggregate principal amount of the Revolving Credit Commitment and (ii) the aggregate principal amount of Term Loan, in each case, of such Lender immediately prior to the Amendment No. 2 Effective Date.

4.     Amendment, Modification and Waiver. This Amendment may not be amended, modified or             

waived except by an instrument or instruments in writing signed and delivered on behalf of each

of the parties hereto.

5.     Entire Agreement. This Amendment, the Credit Agreement and the other Loan Documents

constitute the entire agreement among the parties with respect to the subject matter hereof and     

thereof and supersede all other prior agreements and understandings, both written and verbal,

among the parties or any of them with respect to the subject matter hereof.

6.     GOVERNING LAW. THIS AMENDMENT AND ANY CLAIMS, CONTROVERSY,             

8.     Counterparts. This Amendment may, if agreed by the Administrative Agent, be in the form of

an Electronic Record and may be executed using Electronic Signatures (including, without

limitation, facsimile and .pdf) and shall be considered an original, and shall have the same legal

effect, validity and enforceability as a paper record.  This Amendment may be executed in as

many counterparts as necessary or convenient, including both paper and electronic counterparts,

but all such counterparts are one and the same Amendment. For the avoidance of doubt, the

authorization under this paragraph may include, without limitation, use or acceptance by the

Administrative Agent of a manually signed paper Communication which has been converted into

electronic form (such as scanned into PDF format), or an electronically signed Communication

converted into another format, for transmission, delivery and/or retention. Notwithstanding

anything contained herein to the contrary, the Administrative Agent is under no obligation to

accept an Electronic Signature in any form or in any format unless expressly agreed to by it

pursuant to procedures approved by it; provided, further, without limiting the foregoing, (a) to the

extent the Administrative Agent has agreed to accept such Electronic Signature, it shall be

entitled to rely on any such Electronic Signature without further verification and (b) upon the

request of the Administrative Agent any Electronic Signature shall be promptly followed by a

manually executed, original counterpart.

9.     Loan Documents. On and after the Amendment No. 2 Effective Date, this Amendment shall

constitute a “Loan Document” for all purposes of the Credit Agreement and the other Loan

Documents.

11.     Effect of this Amendment. Except as expressly set forth herein, this Amendment shall not by     

implication or otherwise limit, impair, constitute a waiver of, or otherwise affect the rights and

remedies of, the Lenders or the Administrative Agent under the Existing Credit Agreement or any

other Loan Document, and shall not alter, modify, amend or in any way affect any of the terms,

conditions, obligations, covenants or agreements contained in the Existing Credit Agreement or

any other Loan Document, all of which are ratified and affirmed in all respects and shall continue

in full force and effect. The parties hereto acknowledge and agree that this Amendment and the

amendment of the Existing Credit Agreement pursuant to this Amendment and all other Loan

Documents amended and/or executed and delivered in connection herewith shall not constitute a

novation of the Existing Credit Agreement and the other Loan Documents as in effect prior to the

date hereof. Nothing herein shall be deemed to establish a precedent for purposes of interpreting         

the provisions of the Credit Agreement or entitle any Loan Party to a consent to, or a waiver,

amendment, modification or other change of, any of the terms, conditions, obligations, covenants

or agreements contained in the Credit Agreement or any other Loan Document in similar or

different circumstances. This Amendment shall apply to and be effective only with respect to the

provisions of the Credit Agreement and the other Loan Documents specifically referred to herein.

12.     Costs and Expenses. The Borrower agrees to pay, in accordance with Section 10.04 of the Credit     

Agreement, all reasonable out-of-pocket expenses incurred by the Administrative Agent and its

Affiliates in connection with the preparation, execution, delivery and administration of this     

Amendment, including, without limitation, the reasonable and documented fees, charges and

disbursements of counsel to the Administrative Agent with respect hereto and with respect to

advising the Administrative Agent as to its rights and responsibilities hereunder and under the

Credit Agreement.

QUIDELORTHO CORPORATION,
as the Borrower

By:    /s/ Joseph M. Busky

    Name: Joseph M. Busky

    Title: Chief Financial Officer

BANK OF AMERICA, N.A.,
as a Lender

By:    /s/ Joseph L. Corah

    Name: Joseph L. Corah

    Title: Managing Director

PNC BANK, NATIONAL ASSOCIATION
as a Lender

By:    /s/ Courtney Wojcik

    Name: Courtney Wojcik

    Title: Vice President

WELLS FARGO BANK, NATIONAL ASSOCIATION,
as a Lender

By:    /s/ Darin Mullis

    Name: Darin Mullis

    Title: Managing Director

TRUIST BANK,
as a Lender

By:    /s/ Anton Brykalin

    Name: Anton Brykalin

    Title: Director

CITIBANK, N.A.,
as a Lender

By:    /s/ Eugene Yermash

    Name: Eugene Yermash

    Title: Vice President

DNB CAPITAL LLC,
as a Lender

By:    /s/ Kristie Li

    Name: Kristie Li

    Title: Senior Vice President

By:    /s/ Bret Douglas

    Name: Bret Douglas

    Title: Senior Vice President

THE BANK OF NOVA SCOTIA,
as a Lender

By:    /s/ Robb Gass

    Name: Robb Gass

    Title: Managing Director

U.S. BANK NATIONAL ASSOCIATION,
as a Lender

By:    /s/ Tom Priedeman

    Name: Tom Priedeman

    Title: Senior Vice President

CAPITAL ONE, NATIONAL ASSOCIATION,
as a Lender

By:    /s/ Peter Itz

    Name: Peter Itz

    Title: Duly Authorized Signatory

MIZUHO BANK, LTD.,
as a Lender

By:    /s/ John Davies

    Name: John Davies

    Title: Executive Director

THE TORONTO-DOMINION BANK, NEW YORK BRANCH,
as a Lender

By:    /s/ Victoria Roberts

    Name: Victoria Roberts

    Title: Authorized Signatory

MUFG BANK, LTD.,
as a Lender

By:    /s/ Dominic Yung

    Name: Dominic Yung

    Title: Director

HSBC BANK USA, NA,
as a Lender

By:    /s/ Kevin Chinn

    Name: Kevin Chinn

    Title: Senior Vice President

ROYAL BANK OF CANADA,
as a Lender

By:    /s/ Emily Grams

    Name: Emily Grams

    Title: Authorized Signatory

UMPQUA BANK,
as a Lender

By:    /s/ Kevin Foley

    Name: Kevin Foley

    Title: Senior Vice President

BMO BANK, N.A.,
as a Lender

By:    /s/ Douglas Lambell

    Name: Douglas Lambell

    Title: Managing Director

FIFTH THIRD BANK, NATIONAL ASSOCIATION,
as a Lender

By:    /s/ Shailesh Patel

    Name: Shailesh Patel

    Title: Managing Director

THE HUNTINGTON NATIONAL BANK, N.A.,
as a Lender

By:    /s/ Robert Bell

    Name: Robert Bell

    Title: Vice-President

JPMORGAN CHASE BANK, N.A,

as a Lender

By:    /s/ Marcelo Nicolás Osovi Conti

    Name: Marcelo Nicolás Osovi Conti

    Title: Vice President

BARCLAYS BANK PLC,
as a Lender

By:    /s/ Warren Veech III

    Name: Warren Veech III

    Title: Vice President

ING CAPITAL LLC,
as a Lender

By:    /s/ Stephen Farrelly

    Name: Stephen Farrelly

    Title: Managing Director

By:    /s/ Shirin Fozouni

    Name: Shirin Fozouni

    Title: Managing Director

SANTANDER BANK, N.A.,
as a Lender

By:    /s/ Peter Martin

    Name: Peter Martin

    Title: SVP

SOCIETE GENERALE,
as a Lender

By:    /s/ Shelly Yu

    Name: Shelly Yu

    Title: Director

THE GOVERNOR AND COMPANY OF THE BANK OF IRELAND,
as a Lender

By:    /s/ Allise Dowling

    Name: All

    Title: Vice President

If a second signature is necessary:

By:    /s/ Kevin Hughes

    Name: Kevin Hughes

    Title: Director

GOLDMAN SACHS BANK USA,
as a Lender

By:    /s/ Priyankush Goswami

    Name: Priyankush Goswami

    Title: Authorized Signatory

MORGAN STANLEY BANK, N.A.,
as a Lender

By:    /s/ Jake Dowden

    Name: Jake Dowden

    Title: Authorized Signatory

MEGA INTERNATIONAL COMMERCIAL BANK CO., LTD. NEW YORK BRANCH,
as a Lender

By:    /s/ Tsung-Yao Tsai

    Name: Tsung-Yao Tsai

    Title: AVP

BANK OF AMERICA, N.A.,
as the Administrative Agent

By:    /s/ Kevin L. Ahart

    Name: Kevin L. Ahart

    Title: Vice President