Exhibit A Payments Subject to Section 409A

Exhibit 10.2

May 29, 2020

Dear Jeff,

It is my pleasure to confirm our offer to you for the position of Chief Medical Officer at Constellation Pharmaceuticals, Inc. (“the Company” or “Constellation”).  This letter and accompanying enclosures will summarize important details about your employment, should you accept our offer. 

Employment:  You will be employed to serve on a full-time basis in the position of Chief Medical Officer, reporting to the Chief Executive Officer (CEO).  You agree to devote your full business time, best efforts, skill, knowledge, attention, and energies to the advancement of the Company's business and interests and to the performance of your duties and responsibilities as an employee of the Company, effective on such date as is mutually agreed upon by you and the Company provided, however, that, with the approval of the Board of Directors, you may serve as a director on board(s) of directors of enterprises that do not compete directly or indirectly with the Company or otherwise conflict with Executive's duties and service to the Company.  

Base Salary: Your base salary will be at the rate of $17,307.69 per bi-weekly pay period (which if annualized equals $450,000), less all applicable taxes and withholdings and which will be paid in accordance with the Company’s regular payroll practices, as in effect from time to time.  Such base rate of compensation may be adjusted from time to time in accordance with normal business practices and in the sole discretion of the Company. 

Annual Discretionary Bonus:  Following the end of each fiscal year, and provided that the Board of Directors of the Company (the “Board”) approves funding an annual bonus pool for such fiscal year, you will be eligible for a retention and performance bonus (the “Performance Bonus”).  The target amount of such Performance Bonus will be 40% of your annualized base salary for the applicable fiscal year, based on the Company’s achievement of its performance goals and your achievement of your performance goals for the fiscal year.  The Board or its designee, in its sole discretion, shall determine whether goals have been achieved, whether a Performance Bonus will be awarded, and the amount, if any, of any Performance Bonus.  Any Performance Bonus will be paid to you following the close of the fiscal year to which it relates (but in no event later than March 15^th).  For 2020 the target amount of the Performance Bonus will be 40% of base salary paid in the current fiscal year.  In any event, you must be an active employee of the Company on the date any Performance Bonus is distributed in order to be eligible for and to earn a bonus award, as it also serves as an incentive to remain employed by the Company.

Sign on Bonus:  You will receive a one-time sign-on bonus in the amount of $25,000.00, less all applicable taxes and withholdings, to be paid on the Company’s first regular pay date whose cutoff date follows your commencement of employment.  Please note that if, prior to the one-year anniversary of your start date, you resign your employment without Good Reason (as defined below) or your employment is terminated for Cause (as defined below), you will be required to repay the Company (within thirty (30) days following your separation date) an amount equal to $2,083.33 per complete calendar month remaining between your separation date and the one-year anniversary of your start date You hereby agree that any amount to be repaid to the Company may be deducted from your final pay consistent with applicable law.  

Withholdings:  All compensation payable to you shall be subject to applicable taxes and withholdings.

Initial Stock Option Grant  You will be granted an option to purchase up to 133,000 shares of the Company’s common stock (the “Initial Option”), at a price equal to the fair market value of the common stock on the date of the grant, as determined by the Board.  This Initial Option will be granted within sixty (60) days of your start date of active employment in accordance with the Company’s standard practices for approval of new hire stock option grants, and shall be subject to the standard terms and conditions of the Constellation Pharmaceuticals Stock Option Plan and the stock option agreement provided in connection therewith, as amended from time to time.  As set forth in the stock option agreement, the Initial Option will vest over four years at the rate of 25% after twelve months of the grant date and an additional 6.25% per quarter thereafter in accordance with the specific terms provided in the stock option agreement.  

Performance Stock Option Grant:  Following the end of each fiscal year, and provided that the Board approves employee stock option grants, you will be eligible for a performance-based option grant (the “Performance Grant”).  The target amount of such grant is based on the Company’s achievement of its performance goals and your individual performance for the fiscal year.  The Board or its designee, in its sole discretion, shall determine whether goals have been achieved and whether an option grant will be awarded.  Any Performance Grant will be subject to the terms and conditions of the Constellation Pharmaceuticals Stock Option Plan and the stock option agreement provided in connection therewith, as amended from time to time. 

Relocation: You will receive a relocation bonus in the amount of $75,000, which shall be grossed up for income taxes in accordance with the Company’s tax policies, to be paid on the first pay date following commencement of your employment.  Should you resign your employment without Good Reason (as defined below) or be terminated for Cause (as defined below) by Constellation within the first 24 months of employment, you will be required to repay the Company 1/24^th of the amount paid to you above, including the gross-up, multiplied by each

complete calendar month which remains from your first day of employment to the second anniversary of your start date. You hereby agree that any amount to be repaid to the Company may be deducted from your final pay consistent with applicable law.  

Benefits:   You may participate in any and all benefit programs that the Company establishes and makes available to its employees from time to time, provided that you are eligible under (and subject to all provisions of) the plan documents governing those programs, including the Company’s 401(k) plan, which is currently being offered through Fidelity Investments.  Enclosed is a summary of the benefits that are currently provided to the employees of Constellation Pharmaceuticals.  Please note that the benefits made available by the Company, and the rules, terms, and conditions for participation in such benefit plans, may be changed by the Company at any time, and from time to time without advance notice.

Change In Control: The Company has adopted a Change in Control Severance Plan (the “Plan”), in which you are eligible to participate and that will be provided to you under separate cover.  The Plan is the sole agreement between the Company and you governing any compensation and/or benefits, equity or otherwise, that you may be eligible to receive if your employment with the Company (or its successor in a “Change in Control” (as defined in the Plan)) is terminated other than for “Cause” (as defined in the Plan) or terminates for “Good Reason” (as defined in the Plan) during the Protected Period (as defined in the Plan), but not in the event of death or disability.  In the event there is a conflict between the terms of this offer letter and the terms of the Plan, the terms of the Plan shall govern.  For the avoidance of doubt, if you are eligible for benefits under the Plan, you will not be eligible to receive the Severance Benefits (as defined below).  Any acceleration provisions under the Plan will apply to both the Initial Option and any Performance Grant.

Employment At-Will:  This offer letter is not intended to create or constitute an employment agreement or contract between you and Constellation for any definite period of time. If you accept the Company’s offer of employment, your employment with the Company will be on an “at-will” basis, meaning that you will have the right to terminate your employment relationship with Constellation at any time for any reason, with or without notice. Similarly, Constellation will have the right to terminate its employment relationship with you at any time for any reason, with or without notice.  The at-will nature of your employment may only be changed by a written agreement signed by you and the CEO that expressly states the intention to modify the at-will nature of your employment.  Similarly, nothing in this letter shall be construed as an agreement, either express or implied, to pay you any compensation or grant you any benefit beyond the end of your employment with the Company, except as otherwise explicitly set forth herein.

Severance Benefits Not in Connection With a Change in Control: 

Without limiting the at-will nature of your employment with the Company, in the event that, outside of the Protected Period (as defined in the Plan) Constellation terminates your employment without Cause (as defined below) or you resign your employment for Good Reason (as defined below), and subject to the Severance Conditions set forth below, Constellation shall: (i) pay you in one lump sum a severance payment equivalent to twelve (12) months of your then current base salary which amount shall, if your separation occurs prior to the one-year anniversary of your start date, be multiplied by a fraction, the numerator of which is the number of days from the start date through and including the date employment ends and the denominator of which is 365, less all applicable taxes and withholdings (the “Severance Pay”); and (ii) if you are eligible for and timely elect to continue receiving group medical and/or dental insurance under COBRA, until the earlier of (x) the date that is twelve (12) months following your separation date, and (y) the date on which you obtain alternative coverage (as applicable, the “COBRA Contribution Period”), continue to pay the share of the premiums for such coverage to the same extent it was paying such premiums on your behalf immediately prior to your separation date (though if, as a result of a change in legal requirements, the Company’s provision of payments for COBRA will violate the nondiscrimination requirements of applicable law, this COBRA benefit will not apply) (collectively, the “Severance Benefits”).

The Company’s obligation to provide you with the Severance Benefits is contingent upon your entering into a Severance and Release of Claims Agreement (the “Severance Agreement”) in a form to be provided by the Company (which will include, at a minimum, a release of all releasable claims you may have and your agreement to non-disparagement, confidentiality, and cooperation obligations).  The Severance Agreement must be signed by you, and any applicable revocation period with respect thereto must have expired, by the 60^th day following the end of your employment (or such shorter period as the Company may specify) (the “Severance Conditions”).  Payment of the Severance Pay will be made on the first regular payday after the Severance Agreement becomes effective; provided, however, that if the 60^th day following your separation date occurs in the calendar year following the year of your separation, then payment shall not be made before January 1 of such subsequent calendar year.

Cause:  For purposes of this offer letter, “Cause” shall mean (as determined by the Board in its reasonable judgment) (i) a material breach of any material term of any applicable offer letter or agreement between you and the Company, including the Employee Non-Competition, Non-Solicitation, Confidentiality and Assignment Agreement referred to below, (ii) your plea of guilty or nolo contendere to, or your conviction of, a felony offense or a crime of dishonesty, (iii) your repeated unexplained or unjustified absences or refusals or failures to carry out the lawful directions of the Board or the CEO, or (iv) your willful misconduct that results or is reasonably likely to result in material harm to the Company.  

Good Reason:   For purposes of this offer letter, Good Reason is defined as (i) a material reduction of your base salary; (ii) a material diminution of your authority, duties, or responsibilities; (iii) a requirement that your principal place of providing services to the Company change by more than 50 miles, other than in a direction that reduces your daily commuting distance; or (iv) any material breach by the Company of a material provision of any agreement between you and the Company under which you provide services. Notwithstanding the occurrence of any of the foregoing events or circumstances, a resignation shall not be deemed to constitute resignation for Good Reason unless (x) you give the Company a written notice of the purported Good Reason (no more than 90 days after the initial existence of such event or circumstance), (y) such event or circumstance has not been fully corrected (and you have not been reasonably compensated for any losses or damages resulting therefrom) within 30 days following the Company’s receipt of such notice, and (z) if the Company does not correct, you end your employment not more than 30 days following the period to correct in (y).

Payments Subject to Section 409A: This offer letter, and any payments or other benefits under this offer letter, is intended to be exempt from or to comply with the provisions of Section 409A of the Internal Revenue Code of 1986, as amended ("Section 409A") and shall, to the extent practicable, be construed in accordance with such intention and consistent with Exhibit A to this offer letter.   

Employment Eligibility:  This offer of employment is contingent upon satisfactory reference checks, your signing Constellation’s standard form of Employee Non-Solicitation, Confidentiality and Assignment Agreement (the “Non-Compete”), a copy of which is enclosed, and I-9 Employment Verification.  You will be required to submit documentation that establishes your identity and employment eligibility in accordance with the US Immigration and Naturalization requirements within the first three days of your employment with the Company. 

Company Policies and Procedures:  As an employee of the Company, you will be required to comply with all Company policies and procedures.  Violations of the Company's policies may lead to immediate termination of your employment.  Further, the Company's premises, including all workspaces, furniture, documents, and other tangible materials, and all information technology resources of the Company (including computers, data and other electronic files, and all internet and email) are subject to oversight and inspection by the Company at any time.  Company employees should have no expectation of privacy with regard to any Company premises, materials, resources, or information.

Miscellaneous:  You represent that you are not bound by any employment contract, restrictive covenant or other restriction preventing you from entering into employment with or carrying out your responsibilities for the Company, or which is in any way inconsistent with the terms of this letter.  If there are any agreements of any type that you are aware of which may impact or limit your ability to perform your job at the Company, please let us know as soon as possible.

Please note that this offer letter is your formal offer of employment and supersedes any and all prior or contemporaneous agreements, discussions and understandings, whether written or oral, relating to the subject matter of this letter or your employment with the Company.  The resolution of any disputes under this letter will be governed by Massachusetts law.

Please indicate your acceptance of this offer by signing in the appropriate space below and returning a signed copy of this offer letter along with a signed copy of the Employee Agreement to the attention of Brenda Sousa at Constellation Pharmaceuticals.  

            We are all very excited about the opportunity to work with you, Jeff.  Feel free to contact Brenda Sousa or me if you have any questions or need more information.  On behalf of all our team members, let me extend a sincere welcome.

 Sincerely,

_/s/ Jigar Raythatha___________ 

Jigar Raythatha

President & CEO

Constellation Pharmaceuticals, Inc.

The foregoing correctly sets forth the terms of my at-will employment with Constellation Pharmaceuticals, Inc.  I am not relying on any representations other than those set forth above.

/s/ Jeffrey S. Humphrey, MDMay 27, 2020

Jeffrey S. Humphrey, MD Date

Enclosures:

~Summary of Constellation Benefits

~Constellation’s Employee Non-Solicitation, Confidentiality and Assignment Agreement

Exhibit A

Payments Subject to Section 409A

The following rules shall apply with respect to distribution of the payments and benefits, if any, to be provided under this offer letter in connection with your termination of employment, which must, to the extent required by Section 409A, constitute a “separation from service” (as defined under Section 409A):