First Amendment to Separation and Consulting Agreement dated July 20, 2021, between Registrant and Brandi L. Roberts

Exhibit 10.1

FIRST AMENDMENT TO CONSULTING AGREEMENT

This First Amendment to the Consulting Agreement (the “Amendment”) is entered into as of July 20, 2021 among Brandi L. Roberts, (“Consultant”) and Lineage Cell Therapeutics, Inc., (“Lineage”) (collectively, the “Parties”).

WHEREAS, the Parties have previously entered into that certain Separation and Consulting Agreement, dated January 20, 2021 (the “Agreement”);

WHEREAS, the Parties desire to amend sections of the Agreement.

NOW, THEREFORE, in consideration of the premises and mutual promises and covenants herein and for good and valuable consideration, the Parties agree as follows:

(a) Consulting Period. The Consulting Relationship will be deemed to have commenced on the Separation Date and will continue until August 20, 2021, unless terminated earlier pursuant to Section 3(g) below (the “Consulting Period”). The Consulting Period can be extended only by a writing signed by you and the Chief Executive Officer of Lineage.

[Signatures Found on Following Page]

IN WITNESS WHEREOF, the parties have executed this Amendment by their duly authorized officers as of the date first above written.