BIOSPHERE MEDICAL INC Contracts & Agreements

CONVERTIBLE PROMISSORY NOTE (Filed With SEC on August 13, 2010)

GUARANTY (Filed With SEC on August 13, 2010)

AMENDMENT NO. 1 TO STOCKHOLDER AND VOTING AGREEMENT (Filed With SEC on June 3, 2010)

AGREEMENT AND PLAN OF MERGER by and among MERIT MEDICAL SYSTEMS, INC. MERIT BIOACQUISITION CO. and BIOSPHERE MEDICAL, INC. Dated as of May 13, 2010 (Filed With SEC on May 14, 2010)

FIFTHAMENDMENT TO LEASE (Filed With SEC on March 12, 2010)

ConfidentialMaterials omitted and filed separately with the Securitiesand Exchange Commission. Asterisks denote omissions. INTERNATIONAL DISTRIBUTION AGREEMENT (Filed With SEC on August 13, 2009)

BIOSPHEREMEDICAL, INC. 2006STOCK INCENTIVE PLAN (Filed With SEC on May 20, 2009)

BIOSPHERE MEDICAL, INC. 2000 Employee Stock Purchase Plan (Filed With SEC on May 20, 2009)

Rider # 3 to the January 5, 1998 Agreement (Filed With SEC on March 20, 2009)

FOURTHAMENDMENT TO LEASE (Filed With SEC on January 8, 2009)

SECOND ACKNOWLEDGEMENT AND AMENDMENT AGREEMENT (Filed With SEC on December 23, 2008)

ACKNOWLEDGEMENTAND AMENDMENT AGREEMENT (Filed With SEC on December 23, 2008)

FOURTHACKNOWLEDGEMENT AND AMENDMENT AGREEMENT (Filed With SEC on December 23, 2008)

BIOSPHEREMEDICAL, INC. 2006STOCK INCENTIVE PLAN (Filed With SEC on May 20, 2008)

BIOSPHERE MEDICAL, INC. 2000 Employee Stock Purchase Plan (Filed With SEC on May 20, 2008)

ConfidentialMaterials omitted and filed separately with the Securities andExchange Commission. Asterisks denoteomissions. (Filed With SEC on March 26, 2008)

ACKNOWLEDGEMENTAND AMENDMENT AGREEMENT (Filed With SEC on October 12, 2007)

THIRDACKNOWLEDGEMENT AND AMENDMENT AGREEMENT (Filed With SEC on October 12, 2007)

FOURTHMODIFICATION TO CREDIT AGREEMENT AND PROMISSORY NOTE (Filed With SEC on July 3, 2007)

ACKNOWLEDGEMENTAND AMENDMENT AGREEMENT (Filed With SEC on May 14, 2007)

SECONDACKNOWLEDGEMENT AND AMENDMENT AGREEMENT (Filed With SEC on May 14, 2007)

CERTIFICATE OF AMENDMENT OF THE AMENDED CERTIFICATE OF INCORPORATION OF BIOSPHERE MEDICAL, INC. Pursuant toSection 242 of the General Corporation Law of the State of Delaware (Filed With SEC on March 27, 2007)

BIOSPHEREMEDICAL, INC. AMENDMENTNO. 1 TO 2006 STOCK INCENTIVE PLAN (Filed With SEC on August 9, 2006)

BIOSPHERE MEDICAL, INC. 2006 STOCK INCENTIVE PLAN (Filed With SEC on May 16, 2006)

BioSphere Medical, Inc. Incentive Stock Option Agreement Granted Under 2006 StockIncentive Plan (Filed With SEC on May 16, 2006)

BioSphere Medical, Inc. Nonstatutory Stock Option Agreement Granted Under 2006 Stock Incentive Plan (Filed With SEC on May 16, 2006)

BioSphere Medical, Inc. Restricted Stock Agreement Granted Under 2006 Stock Incentive Plan (Filed With SEC on May 16, 2006)

THIRDAMENDMENT TO LEASE (Filed With SEC on February 28, 2006)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on February 21, 2006)

REGISTRATION RIGHTS AGREEMENT (Filed With SEC on February 21, 2006)

SEPARATION AND SETTLEMENT AGREEMENT AND RELEASE (Filed With SEC on June 17, 2005)

AMENDMENTNO. 1 TO CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTSOF SERIES A PREFERRED STOCK OF BIOSPHERE MEDICAL, INC. Pursuant to Section 242 ofthe General Corporation Law... (Filed With SEC on May 23, 2005)

BioSphere Medical Inc. NON-STATUTORY STOCK OPTION AGREEMENT (Filed With SEC on March 29, 2005)

BioSphere Medical, Inc. Incentive Stock OptionAgreement (Filed With SEC on March 29, 2005)

BioSphere Medical, Inc. Form of NonstatutoryStock Option Agreement Granted Under 1997 Stock Incentive Plan (Filed With SEC on March 29, 2005)

BioSphere Medical, Inc. Form of Restricted Stock Agreement Granted Under 1997 Stock Incentive Plan (Filed With SEC on March 29, 2005)

COMPENSATIONOF EXECUTIVE OFFICERS OF BIOSPHERE MEDICAL, INC. (Filed With SEC on March 29, 2005)

COMPENSATIONPROGRAM FOR NON-EMPLOYEE DIRECTORS OF BIOSPHERE MEDICAL, INC. (Filed With SEC on March 29, 2005)

SECONDAMENDMENT TO LEASE (Filed With SEC on January 27, 2005)

SEVERANCE AGREEMENT ANDGENERAL RELEASE (Filed With SEC on January 27, 2005)

RESTRICTIVECOVENANTS AGREEMENT (Filed With SEC on December 30, 2004)

AMENDMENT NO. 1 TO WARRANT NO. 2004-1 TO PURCHASE 200,000 SHARES OF COMMON STOCK, PAR VALUE $0.01 PER SHARE (Filed With SEC on December 30, 2004)

AMENDMENTNO. 1 TO WARRANT NO. 2004-2 TO PURCHASE 200,000 SHARES OF COMMON STOCK, PAR VALUE $0.01 PER SHARE (Filed With SEC on December 30, 2004)

CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF (Filed With SEC on November 15, 2004)

SECURITIES PURCHASE AGREEMENT (Filed With SEC on November 15, 2004)

INVESTOR RIGHTS AGREEMENT (Filed With SEC on November 15, 2004)

COMMON STOCK, PAR VALUE $0.01 PER SHARE (Filed With SEC on November 15, 2004)

SECOND MODIFICATION TO CREDIT AGREEMENT AND PROMISSORY NOTE (Filed With SEC on November 12, 2004)

SEVERANCE AGREEMENT AND GENERAL RELEASE (Filed With SEC on November 8, 2004)

BIOSPHERE MEDICAL, INC. (Filed With SEC on November 8, 2004)

BIOSPHERE MEDICAL, INC. (Filed With SEC on May 17, 2004)

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BIOSPHERE MEDICAL INC Contracts & Agreements