First Amendment to Executive Employment Agreement between BioSig Technologies Inc. and Anthony Amato

Exhibit 10.4

First AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT

This First AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT (this “Amendment”), entered into as of the Effective Time (as defined below), by and between Anthony Amato (“Executive”) and BioSig Technologies Inc., a Delaware corporation (the “Company”), for the purpose of amending that certain Executive Employment Agreement, dated as of August 1, 2024 by and between Executive and the Company (the “Agreement”). Terms used in this Amendment with initial capital letters that are not otherwise defined herein shall have the meanings ascribed to such terms in the Agreement.

WHEREAS, the Company and Executive desire to state in writing the terms and conditions of their agreement and understandings with respect to the Amendment of the Agreement effective as of the effective time (the “Effective Time”) of the proposed transaction by and among the BST Sub ULC, an unlimited liability company organized under the laws of the Province of British Columbia and a wholly-owned subsidiary of the Company (“ExchangeCo”), 1540875 B.C. Ltd., a company organized under the laws of the Province of British Columbia and a wholly-owned subsidiary of the Parent (“Callco”), Streamex Exchange Corporation, a corporation organized under the laws of the Province of British Columbia (“Streamex”), each shareholder of Streamex and 1540873 B.C. Ltd., as trustee of the trust formed pursuant to the Exchange Rights Agreement (the “Trustee”), pursuant to which, among other things, the Company, through ExchangeCo, will purchase from each Shareholder, and each Shareholder will sell to the Company, through ExchangeCo, all of the issued and outstanding shares of Streamex (the “Transaction”), which Transaction is governed by the Purchase Agreement by and among each of the Company, ExchangeCo, Callco, Streamex and the Trustee, dated as of May 23, 2025 (the “Purchase Agreement”);

WHEREAS, Section 11(a) of the Agreement provides that any amendment to the Agreement must be executed by all parties to the Agreement; and

WHEREAS, the parties mutually desire to modify certain provisions that would otherwise apply to Executive’s severance provisions pursuant to the Agreement.

NOW, THEREFORE, pursuant to Section 11(a) of the Agreement, in consideration of the mutual provisions, conditions, and covenants contained herein, and other good and valuable consideration, the adequacy of which is hereby acknowledged, the parties hereby agree as follows:

(c) Resignation in Connection with the Transaction. If Executive resigns in accordance with the terms and provisions of the Purchase Agreement, then the following severance provisions shall apply to Executive:

Notwithstanding anything to the contrary in any applicable equity incentive plan, grant agreement, or Company policy, the Company agrees to the following treatment of the Executive’s equity upon

his resignation pursuant to the Purchase Agreement:

As of the Effective Date, all equity awards previously granted to the Executive — including but not limited to vested and unvested stock options, restricted stock units (RSUs), performance stock units (PSUs), and any other equity-based awards —shall be accelerated, deemed fully vested and nonforfeitable. All such awards shall become fully vested and, to the extent applicable, immediately exercisable.

The post-resignation exercise period for all vested stock options (including those that become vested under this Agreement) shall be extended to the later of:

(a) the original expiration date of the applicable option(s), or

(b) 36 months following the Effective Date.

In the event that any payments under this Agreement or otherwise are required to be reduced as described in this Section 7(e), the adjustment will be made by reducing the cash severance, if any, due to Executive pursuant to Section 4(c).

[Remainder of the Page Intentionally Left Blank;

Signature Page Follows]

IN WITNESS WHEREOF, the parties have executed this Amendment to be effective as of the Effective Date.

[Signature Page to First Amendment to Employment Agreement]

Exhibit a

form of RESIGNATION AND RELEASE

[Exhibit A to First Amendment to Employment Agreement]