ASSET PURCHASE AGREEMENT

Exhibit 10.25

ASSET PURCHASE AGREEMENT

This Asset Purchase Agreement (“Agreement”) is entered into as of November 30, 2011 (“Effective Date”) by and between SA Pathology, a unit of Central Adelaide Local Health Network Inc, incorporated under the Health Care Act of 2008, having its principal place of business at Frome Road, Adelaide, South Australia, Australia (“SA Pathology”) and BMRN Bears Ltd., an Irish corporation resident in The Bahamas having its principle place of business at 60 Montrose Ave, Nassau, Bahamas (“BioMarin”) (each of the above companies also referred to individually as “Party” and collectively as “Parties”).

RECITALS

WHEREAS, SA Pathology and BioMarin’s Affiliate, BioMarin Pharmaceutical Inc., (“BPI”) have entered into a License Agreement dated February 7, 2007 (“License Agreement”) relating to certain intellectual property related to N-acetylgalactosamine-4-sulfatase whereby BioMarin was granted an exclusive license to such intellectual property, referred to herein as the Transferred Assets; and

WHEREAS, SA Pathology is the exclusive owner of the Transferred Assets; and

WHEREAS, BioMarin desires to acquire from SA Pathology, and SA Pathology desires to assign to BioMarin, the Transferred Assets subject to and in accordance with the provisions of this Agreement.

NOW, THEREFORE, in consideration of the mutual covenants and promises contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, SA Pathology and BioMarin agree as follows:

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If to SA PATHOLOGY:

Berg Lawyers

89 King William Street

Adelaide, SA 5000

Australia

ATTN: Shaun Berg

If to BioMarin:

BMRN Bears Ltd.

60 Montrose St.

Nassau, NP

The Bahamas

ATTN: Managing Director

With a copy to:

BioMarin Pharmaceutical Inc.

105 Digital Drive

Novato, California 94949

ATTN: General Counsel

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(Signature Page Follow)

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IN WITNESS WHEREOF, the Parties have executed this Agreement effective as of the date first above written.

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Exhibit A

TRANSFERRED PATENTS

Exhibit B

Patent Assignment

ASSIGNMENT AGREEMENT

This assignment agreement (“Assignment”) is entered into the 30th day of November, 2011 (“Effective Date”) by and between SA Pathology, a unit of Central Adelaide Local Health Network Inc., incorporated under the Health Care Act of 2008, having its principal place of business at Frome Road, Adelaide, South Australia, Australia (“Assignor”), and BMRN Bears Ltd., an Irish corporation resident in The Bahamas having its principle place of business at 60 Montrose Ave, Nassau, Bahamas (“Assignee”).

For good and valuable consideration, the receipt and sufficiency of which are agreed, Assignor hereby irrevocably sells, assigns and transfers to Assignee and its successors, assigns and legal representatives, Assignor’s entire right, title and interest, both legal and equitable, throughout the world, in the patents and patent applications listed in the attached Schedule A, and to the inventions described therein and improvements thereof, all related U.S., PCT and foreign patent applications including those claiming priority thereto anywhere in the world, all continuations, divisionals and continuations-in-part of any of the foregoing, patents issuing from any of the foregoing, and reissues, reexaminations, extensions and foreign equivalents thereof and supplementary protection certificates allowed on any of the foregoing (collectively the “Patent Rights”) for Assignee’s own use and enjoyment, and for the use and enjoyment of its successors, assigns or other legal representatives, as fully and entirely as the same would have been held and enjoyed by Assignor if this Assignment and sale had not been made; together with all income, royalties, damages or payments due or payable as of the Effective Date or thereafter, including, without limitation, all claims for damages by reason of past, present or future infringement or other unauthorized use of the Patent Rights, with the right to sue for, and collect the same for its own use and enjoyment, and for the use and enjoyment of its successors, assigns, or other legal representatives.

Upon the request of Assignee, the undersigned agrees to execute any and all documents and take actions reasonably requested to effectuate this assignment and Assignee’s rights in the Patent Rights, including any oath or affidavit relating thereto, to cooperate to the best of the ability of the undersigned with Assignee in preparing and executing statements and giving and producing evidence in support of the Patent Rights, and to perform any and all acts reasonably requested by Assignee to obtain, enforce and defend the Patent Rights and vest all rights therein to Assignee as fully and entirely as the same would have been held and enjoyed by the undersigned if this Assignment had not been executed.

The parties execute and deliver this Assignment by their respective signatories below.

Exhibit C

BPI Acknowledgement

BioMarin Pharmaceutical Inc., a Delaware corporation (“BPI”) hereby acknowledges that it affiliate, BMRN Bears Ltd., an Irish corporation resident in The Bahamas (“BBL”), is purchasing certain intellectual property under lying that certain License Agreement by and between BPI and SA Pathology, a unit of Central Adelaide Local Health Network Inc, incorporated under the Health Care Act of 2008 (“SA Pathology”) dated February 7, 2007 (“License Agreement”) pursuant to an Asset Purchase Agreement dated November 30, 2011 (the “APA”). BPI further acknowledges that SA Pathology is entering into the APA in reliance on this acknowledgement and the commitments made by BPI herein. On such basis, BPI commits that:

Executed on behalf of BioMarin Pharmaceutical Inc.

Exhibit D

Wire Transfer Instructions

[Account Information Redacted.]