Specimen Unit Certificate

EXHIBIT 4.1

CUSIP ###-###-####

UNITS CONSISTING OF ONE SHARE OF COMMON STOCK,

ONE WARRANT AND ONE RIGHT

THIS CERTIFIES THAT ______________________________________________________________

is the owner of _____________________________________________________________________ Units.

Each Unit (“Unit”) consists of one (1) share of common stock, par value $0.0001 per share (“Common Stock”), of Bellevue Life Sciences Acquisition Corporation, a Delaware corporation (the “Company”), one (1) warrant (“Warrant”) and one (1) right (“Right”). Each Warrant entitles the holder to purchase one share of Common Stock for $11.50 per share (subject to adjustment). Each whole Warrant will become exercisable on the date that is 30 days after the Company’s completion of an initial merger, share exchange, asset acquisition, stock purchase, recapitalization, reorganization or similar business combination with one or more businesses or entities (a “Business Combination”), and will expire unless exercised before 5:00 p.m., New York City Time, on the fifth anniversary of the completion of an initial Business Combination, or earlier upon redemption or liquidation. Each right entitles the holder thereof to receive one-tenth (1/10) of a share of Common Stock upon the consummation of a Business Combination. Each ten rights entitle the holder thereof to receive one share of Common Stock at the closing of a Business Combination. Fractional shares will not be issued. As a result, a holder must hold rights in multiples of 10 in order to receive shares for all rights held upon the closing of a Business Combination. The Common Stock, Warrant(s) and Rights(s) comprising the Unit(s) represented by this certificate are not transferable separately prior to _____________, 2022, unless Chardan Capital Markets LLC informs the Company of their decision to allow earlier separate trading, except that in no event will the Common Stock, Warrants and Rights be separately tradeable until the Company has filed an audited balance sheet reflecting the Company’s receipt of the gross proceeds of its initial public offering and issued a press release announcing when such separate trading will begin. The terms of the Warrants are governed by a Warrant Agreement, dated as of ___________, 2022 (the “Warrant Agreement”), between the Company and Continental Stock Transfer & Trust Company, as Warrant Agent (the “Warrant Agent”), and are subject to the terms and provisions contained therein, all of which terms and provisions the holder of this certificate consents to by acceptance hereof. The terms of the Rights are governed by a Rights Agreement, dated as of ____________. 2022 (the “Rights Agreement”), between the Company and Continental Stock Transfer & Trust Company, as Rights Agent (the “Rights Agent”), and are subject to the terms and provisions contained therein, all of which terms and provisions the holder of this certificate consents to by acceptance hereof. Copies of the Warrant Agreement and the Rights Agreement are on file at the office of the Warrant Agent and the Rights Agent, respectively, at 1 State Street, 30^th Floor, New York, New York 10004, and are available to any Warrant holder and Rights holder on written request and without cost.

This certificate is not valid unless countersigned by the Transfer Agent and Registrar of the Company. This certificate shall be governed by and construed in accordance with the internal laws of the State of New York. Witness the facsimile seal of the Company and the facsimile signatures of its duly authorized officers.

Bellevue Life Sciences Acquisition Corporation

The Company will furnish without charge to each unitholder who so requests, a statement of the powers, designations, preferences, and relative, participating, optional, or other special rights of each class of stock or series thereof of the Company and the qualifications, limitations, or restrictions of such preferences and/or rights.

The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations:

Additional abbreviations may also be used though not in the above list.

For value received, ___________________________ hereby sell, assign, and transfer unto

                                                                                                                                                                                                                     Units

represented by the within Certificate, and do hereby irrevocably constitute and appoint

to transfer the said Units on the books of the within named Company with full power of substitution in the premises.

Dated ____________________

Signature(s) Guaranteed:

In each case, as more fully described in the Company’s final prospectus dated _________, 2022, the holder(s) of this certificate shall be entitled to receive a pro-rata portion of the funds from the trust account with respect to the common stock underlying this certificate only in the event that (i) the Corporation is forced to liquidate because it does not consummate an initial business combination within the period of time set forth in the Corporation’s Amended and Restated Certificate of Incorporation, as the same may be amended from time to time (the “Charter”) or (ii) if the holder seeks to convert his shares upon consummation of, or sell his shares in a tender offer in connection with, an initial business combination or in connection with certain amendments to the Charter. In no other circumstances shall the holder(s) have any right or interest of any kind in or to the trust account.