Request Letter for SEC Filing of Director Resignation by Applied Molecular Evolution, Inc.

Summary

This letter, dated September 19, 2002, is from Stanley T. Crooke, Peter K. Hilal, and Clive Meanwell to William Huse, President and CEO of Applied Molecular Evolution, Inc. The authors request that the company file a Form 8-K with the SEC to disclose their resignation from the board of directors and to include the full text of their resignation letter. The letter formalizes the request for public disclosure of their departure from the board.

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EX-4.2 4 a84554exv4w2.txt EXHIBIT 4.2 EXHIBIT 4.2 September 19, 2002 William Huse, M.D., Ph.D. President, Chief Executive Officer, and Chairman Applied Molecular Evolution, Inc. 3520 Dunhill Street San Diego, CA 92121 VIA FACSIMILE: 853 ###-###-#### Dear Bill: In conjunction with our September 13, 2002 resignation from AME's board of directors, we request that you file electronically with the Securities and Exchange Commission a Form 8-K, and that you include with the 8-K the full text of our September 13, 2002 letter of resignation. Sincerely, /s/ STANLEY T. CROOKE /s/ PETER K. HILAL /s/ CLIVE MEANWELL Stanley T. Crooke, M.D., Ph.D. Peter K. Hilal, M.D. Clive Meanwell, M.D.